Slc38a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc38a2
Entrez Gene ID	67760
Full Name	solute carrier family 38, member 2
Synonyms	5033402L14Rik,AI316867,ATA2,SAT2,mKIAA1382
General protein information	Preferred Names solute carrier family 38, member 2 Names sodium-coupled neutral amino acid transporter 2 amino acid system A transporter amino acid transporter A2 system A amino acid transporter 2 system A transporter 1 system N amino acid transporter 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001355633.1	NP_001342562.1	sodium-coupled neutral amino acid transporter 2 isoform 2
XM_006521300.3	XP_006521363.1	sodium-coupled neutral amino acid transporter 2 isoform X1
NM_175121.3	NP_780330.2	sodium-coupled neutral amino acid transporter 2
NM_175121.4	NP_780330.2	sodium-coupled neutral amino acid transporter 2 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc38a2	NP_851604.1
Danio rerio (zebrafish)	slc38a2	NP_001038569.1
Homo sapiens (human)	SLC38A2	NP_061849.2
Pan troglodytes (chimpanzee)	SLC38A2	XP_001164321.1
	SLC38A2	XP_002798588.1
Canis lupus familiaris (dog)	SLC38A2	XP_005637001.1
Bos taurus (cattle)	SLC38A2	NP_001075893.1
Mus musculus (house mouse)	Slc38a2	NP_780330.2
Xenopus tropicalis (tropical clawed frog)	slc38a2	NP_001011056.1
Gallus gallus (chicken)	SLC38A2	NP_001025912.1

Gene Ontology
Bibliography

Related articles in PubMed

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Kurogi S, Sekimoto T, Funamoto T, Ota T, Nakamura S, Nagai T, Nakahara M, Yoshinobu K, Araki K, Araki M, Chosa E
Scientific reports740692(2017 Jan)

Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport.
Moen MN, Fj?r R, Hamdani EH, Laerdahl JK, Menchini RJ, Vigeland MD, Sheng Y, Undlien DE, Hassel B, Salih MA, El Khashab HY, Selmer KK, Chaudhry FA
Brain : a journal of neurology139(Pt 12)3109-3120(2016 Dec)

Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.
Tan BS, Rathjen PD, Harvey AJ, Gardner DK, Rathjen J
Mechanisms of development14132-9(2016 08)

A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.
Uno K, Yamada T, Ishigaki Y, Imai J, Hasegawa Y, Sawada S, Kaneko K, Ono H, Asano T, Oka Y, Katagiri H
Nature communications67940(2015 Aug)

Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity.
Krokowski D, Jobava R, Guan BJ, Farabaugh K, Wu J, Majumder M, Bianchi MG, Snider MD, Bussolati O, Hatzoglou M
The Journal of biological chemistry290(29)17822-37(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Changes in transporter expression likely reflect different amino acid requirements during development. Findings include the differential expression of SNAT1 in the inner and outer cells of the compacted morula and nuclear localisation of SNAT2 in the trophectoderm and placental lineages.
Title: Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.

The neuronal mechanism uncovered here serves to coordinate amino acid and lipid levels and contributes to the development of obesity-related hypertriglyceridemia.
Title: A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.

GADD34 promotes cell survival and adaptation to increased extracellular osmolarity by increasing the uptake of small neutral amino acids via the amino acid transporter ATA2.
Title: Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity.

These data reveal an unexpected role for amino acid uptake and the amino acid transporter SNAT2 in regulation of pluripotent cells in culture.
Title: The amino acid transporter SNAT2 mediates L-proline-induced differentiation of ES cells.

The inward current of Na(+) associated with the function of SNAT2 leads to membrane depolarization and activation of voltage-sensitive Ca(2+) channels that mediate Ca(2+) influx, thereby leading to an increase in the [Ca(2+)](i) in enteroendocrine cells.
Title: Amino acid sensing by enteroendocrine STC-1 cells: role of the Na+-coupled neutral amino acid transporter 2.

The following Slc38a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc38a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu51532	NM_001355633.1 Latest version!	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu51532	XM_006521300.3 Latest version!	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu04878	NM_175121.4 Latest version!	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
View Old Accession Versions >>
OMu04878	NM_175121.3	Mus musculus solute carrier family 38, member 2 (Slc38a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc38a2 ( NM_001355633.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342562.1 Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu51532
Clone ID Related Accession (Same CDS sequence)	NM_001355633.1 , XM_006521300.3
Accession Version	NM_001355633.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	sodium-coupled neutral amino acid transporter 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109201.12. On Sep 22, 2017 this sequence version replaced XM_006521300.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.29302.1, SRR1660813.14052.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGCCGACGT GGATCCCGAA AACCAGAACT TTTTACTTGA ATCAAATTTG GGGAAGAAGA 
AGTACGAAAC AGACTTTAAT TCTCTTGACG TTCGTGTCAA TTTTTTCGCT ATACTCCGTC 
CATCTCCTCC TCAAGACTGC CAACGAAGGA GGATCTTTAT TGTACGAACA GTTGGGACAT 
AAGGCGTATG GTCTGGCTGG AAAGCTAGCA GCCTCCGGAT CGATAACCAT GCAGAACATT 
GGGGCTATGT CAAGCTACCT CTTCATAGTG AAATATGAGT TACCTTTGGT GATCAAGGCA 
TTAATGAACA TTGAAGATAC AAATGGGTTG TGGTATCTGA ACGGTGACTA TCTGGTCCTT 
CTGGTGTCCC TTGTCCTCAT TCTTCCATTG TCACTGCTGA GAAATCTAGG ATACTTGGGG 
TACACCAGCG GCCTCTCTCT GCTCTGTATG ATATTTTTCC TGATCGTGGT GATTTGCAAG 
AAGTTTCAGA TCCCTTGCCC CGTGGAAGCT GCTTTGGTGG CCAACGAAAC TGTGAACGGC 
ACCTTTACCC AGGCAGCGTT GGCGTTGGCA TTCAATAGCA CCGCAGACGA TGCTTGCAGG 
CCACGCTATT TCATCTTCAA CTCGCAGACT GTGTATGCAG TACCCATCCT GACGTTTTCC 
TTTGTCTGCC ATCCCGCTGT TCTTCCCATC TACGAAGAGC TAAAGAGCCG CAGCCGGAGA 
CGGATGATGA ACGTGTCCAA GATTTCCTTC TTCGCCATGT TTCTGATGTA CTTGCTCGCT 
GCTCTCTTTG GATACCTGAC CTTTTACGGA CACGTGGAAT CGGAATTGCT GCATACCTAC 
TCCGAGATCG TGGGGACTGA CATTCTTCTC CTTGTTGTCC GATTGGCTGT GCTGGTGGCT 
GTCACCCTCA CGGTCCCAGT AGTTATTTTC CCTATCCGGA GTTCCGTCAC TCACTTACTG 
TGTCCCACAA AAGAGTTCAG CTGGCTCCGG CACAGCATCA TCACCGTGAC CATCTTGTCC 
TTCACCAATT TGCTCGTCAT CTTTGTCCCC ACTATTAGGG ACATCTTCGG GTTCATTGGG 
GCGTCGGCGG CTGCCATGCT GATCTTTATC CTCCCGTCTG CCTTCTACAT CAAGTTAGTG 
AAGAAGGAAC CAATGAGATC CGTGCAAAAG ATTGGGGCTC TGTGTTTTCT CCTGAGTGGC 
ATAGTGGTGA TGATTGGAAG CATGGGCTTG ATTGTGCTGG ATTGGGTCCA CGATGCCTCC 
GCTGCAGGTG GGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342562.1
CDS	530..1807
Translation	MPTWIPKTRTFYLNQIWGRRSTKQTLILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEAALVANETVNGTFTQAALALAFNSTADDACRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWLRHSIITVTILSFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGIVVMIGSMGLIVLDWVHDASAAGGH

Target ORF information:

RefSeq Version	NM_001355633.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355633.1

ORF Insert Sequence:

ATGCCGACGT GGATCCCGAA AACCAGAACT TTTTACTTGA ATCAAATTTG GGGAAGAAGA 
AGTACGAAAC AGACTTTAAT TCTCTTGACG TTCGTGTCAA TTTTTTCGCT ATACTCCGTC 
CATCTCCTCC TCAAGACTGC CAACGAAGGA GGATCTTTAT TGTACGAACA GTTGGGACAT 
AAGGCGTATG GTCTGGCTGG AAAGCTAGCA GCCTCCGGAT CGATAACCAT GCAGAACATT 
GGGGCTATGT CAAGCTACCT CTTCATAGTG AAATATGAGT TACCTTTGGT GATCAAGGCA 
TTAATGAACA TTGAAGATAC AAATGGGTTG TGGTATCTGA ACGGTGACTA TCTGGTCCTT 
CTGGTGTCCC TTGTCCTCAT TCTTCCATTG TCACTGCTGA GAAATCTAGG ATACTTGGGG 
TACACCAGCG GCCTCTCTCT GCTCTGTATG ATATTTTTCC TGATCGTGGT GATTTGCAAG 
AAGTTTCAGA TCCCTTGCCC CGTGGAAGCT GCTTTGGTGG CCAACGAAAC TGTGAACGGC 
ACCTTTACCC AGGCAGCGTT GGCGTTGGCA TTCAATAGCA CCGCAGACGA TGCTTGCAGG 
CCACGCTATT TCATCTTCAA CTCGCAGACT GTGTATGCAG TACCCATCCT GACGTTTTCC 
TTTGTCTGCC ATCCCGCTGT TCTTCCCATC TACGAAGAGC TAAAGAGCCG CAGCCGGAGA 
CGGATGATGA ACGTGTCCAA GATTTCCTTC TTCGCCATGT TTCTGATGTA CTTGCTCGCT 
GCTCTCTTTG GATACCTGAC CTTTTACGGA CACGTGGAAT CGGAATTGCT GCATACCTAC 
TCCGAGATCG TGGGGACTGA CATTCTTCTC CTTGTTGTCC GATTGGCTGT GCTGGTGGCT 
GTCACCCTCA CGGTCCCAGT AGTTATTTTC CCTATCCGGA GTTCCGTCAC TCACTTACTG 
TGTCCCACAA AAGAGTTCAG CTGGCTCCGG CACAGCATCA TCACCGTGAC CATCTTGTCC 
TTCACCAATT TGCTCGTCAT CTTTGTCCCC ACTATTAGGG ACATCTTCGG GTTCATTGGG 
GCGTCGGCGG CTGCCATGCT GATCTTTATC CTCCCGTCTG CCTTCTACAT CAAGTTAGTG 
AAGAAGGAAC CAATGAGATC CGTGCAAAAG ATTGGGGCTC TGTGTTTTCT CCTGAGTGGC 
ATAGTGGTGA TGATTGGAAG CATGGGCTTG ATTGTGCTGG ATTGGGTCCA CGATGCCTCC 
GCTGCAGGTG GGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc38a2 ( XM_006521300.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521363.1 Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51532
Clone ID Related Accession (Same CDS sequence)	NM_001355633.1 , XM_006521300.3
Accession Version	XM_006521300.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	sodium-coupled neutral amino acid transporter 2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521300.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGACGT GGATCCCGAA AACCAGAACT TTTTACTTGA ATCAAATTTG GGGAAGAAGA 
AGTACGAAAC AGACTTTAAT TCTCTTGACG TTCGTGTCAA TTTTTTCGCT ATACTCCGTC 
CATCTCCTCC TCAAGACTGC CAACGAAGGA GGATCTTTAT TGTACGAACA GTTGGGACAT 
AAGGCGTATG GTCTGGCTGG AAAGCTAGCA GCCTCCGGAT CGATAACCAT GCAGAACATT 
GGGGCTATGT CAAGCTACCT CTTCATAGTG AAATATGAGT TACCTTTGGT GATCAAGGCA 
TTAATGAACA TTGAAGATAC AAATGGGTTG TGGTATCTGA ACGGTGACTA TCTGGTCCTT 
CTGGTGTCCC TTGTCCTCAT TCTTCCATTG TCACTGCTGA GAAATCTAGG ATACTTGGGG 
TACACCAGCG GCCTCTCTCT GCTCTGTATG ATATTTTTCC TGATCGTGGT GATTTGCAAG 
AAGTTTCAGA TCCCTTGCCC CGTGGAAGCT GCTTTGGTGG CCAACGAAAC TGTGAACGGC 
ACCTTTACCC AGGCAGCGTT GGCGTTGGCA TTCAATAGCA CCGCAGACGA TGCTTGCAGG 
CCACGCTATT TCATCTTCAA CTCGCAGACT GTGTATGCAG TACCCATCCT GACGTTTTCC 
TTTGTCTGCC ATCCCGCTGT TCTTCCCATC TACGAAGAGC TAAAGAGCCG CAGCCGGAGA 
CGGATGATGA ACGTGTCCAA GATTTCCTTC TTCGCCATGT TTCTGATGTA CTTGCTCGCT 
GCTCTCTTTG GATACCTGAC CTTTTACGGA CACGTGGAAT CGGAATTGCT GCATACCTAC 
TCCGAGATCG TGGGGACTGA CATTCTTCTC CTTGTTGTCC GATTGGCTGT GCTGGTGGCT 
GTCACCCTCA CGGTCCCAGT AGTTATTTTC CCTATCCGGA GTTCCGTCAC TCACTTACTG 
TGTCCCACAA AAGAGTTCAG CTGGCTCCGG CACAGCATCA TCACCGTGAC CATCTTGTCC 
TTCACCAATT TGCTCGTCAT CTTTGTCCCC ACTATTAGGG ACATCTTCGG GTTCATTGGG 
GCGTCGGCGG CTGCCATGCT GATCTTTATC CTCCCGTCTG CCTTCTACAT CAAGTTAGTG 
AAGAAGGAAC CAATGAGATC CGTGCAAAAG ATTGGGGCTC TGTGTTTTCT CCTGAGTGGC 
ATAGTGGTGA TGATTGGAAG CATGGGCTTG ATTGTGCTGG ATTGGGTCCA CGATGCCTCC 
GCTGCAGGTG GGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521363.1
CDS	526..1803
Translation	MPTWIPKTRTFYLNQIWGRRSTKQTLILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEAALVANETVNGTFTQAALALAFNSTADDACRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWLRHSIITVTILSFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGIVVMIGSMGLIVLDWVHDASAAGGH

Target ORF information:

RefSeq Version	XM_006521300.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521300.3

ORF Insert Sequence:

ATGCCGACGT GGATCCCGAA AACCAGAACT TTTTACTTGA ATCAAATTTG GGGAAGAAGA 
AGTACGAAAC AGACTTTAAT TCTCTTGACG TTCGTGTCAA TTTTTTCGCT ATACTCCGTC 
CATCTCCTCC TCAAGACTGC CAACGAAGGA GGATCTTTAT TGTACGAACA GTTGGGACAT 
AAGGCGTATG GTCTGGCTGG AAAGCTAGCA GCCTCCGGAT CGATAACCAT GCAGAACATT 
GGGGCTATGT CAAGCTACCT CTTCATAGTG AAATATGAGT TACCTTTGGT GATCAAGGCA 
TTAATGAACA TTGAAGATAC AAATGGGTTG TGGTATCTGA ACGGTGACTA TCTGGTCCTT 
CTGGTGTCCC TTGTCCTCAT TCTTCCATTG TCACTGCTGA GAAATCTAGG ATACTTGGGG 
TACACCAGCG GCCTCTCTCT GCTCTGTATG ATATTTTTCC TGATCGTGGT GATTTGCAAG 
AAGTTTCAGA TCCCTTGCCC CGTGGAAGCT GCTTTGGTGG CCAACGAAAC TGTGAACGGC 
ACCTTTACCC AGGCAGCGTT GGCGTTGGCA TTCAATAGCA CCGCAGACGA TGCTTGCAGG 
CCACGCTATT TCATCTTCAA CTCGCAGACT GTGTATGCAG TACCCATCCT GACGTTTTCC 
TTTGTCTGCC ATCCCGCTGT TCTTCCCATC TACGAAGAGC TAAAGAGCCG CAGCCGGAGA 
CGGATGATGA ACGTGTCCAA GATTTCCTTC TTCGCCATGT TTCTGATGTA CTTGCTCGCT 
GCTCTCTTTG GATACCTGAC CTTTTACGGA CACGTGGAAT CGGAATTGCT GCATACCTAC 
TCCGAGATCG TGGGGACTGA CATTCTTCTC CTTGTTGTCC GATTGGCTGT GCTGGTGGCT 
GTCACCCTCA CGGTCCCAGT AGTTATTTTC CCTATCCGGA GTTCCGTCAC TCACTTACTG 
TGTCCCACAA AAGAGTTCAG CTGGCTCCGG CACAGCATCA TCACCGTGAC CATCTTGTCC 
TTCACCAATT TGCTCGTCAT CTTTGTCCCC ACTATTAGGG ACATCTTCGG GTTCATTGGG 
GCGTCGGCGG CTGCCATGCT GATCTTTATC CTCCCGTCTG CCTTCTACAT CAAGTTAGTG 
AAGAAGGAAC CAATGAGATC CGTGCAAAAG ATTGGGGCTC TGTGTTTTCT CCTGAGTGGC 
ATAGTGGTGA TGATTGGAAG CATGGGCTTG ATTGTGCTGG ATTGGGTCCA CGATGCCTCC 
GCTGCAGGTG GGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc38a2 ( NM_175121.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780330.2 Mus musculus solute carrier family 38, member 2 (Slc38a2), mRNA.

Price & Availability↑

CloneID	OMu04878
Clone ID Related Accession (Same CDS sequence)	NM_175121.3 , NM_175121.4
Accession Version	NM_175121.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-24
Organism	Mus musculus(House mouse)
Product	sodium-coupled neutral amino acid transporter 2
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC048178.1. On Jun 9, 2003 this sequence version replaced NM_175121.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048178.1, SRR1660821.9254.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGAAGAAGA CCGAAATGGG AAGGTTCAAC ATCTCCCCGG ATGAGGACAG CAGCAGTTAC 
AGCTCCAACA GTGACTTCAA CTACTCATAC CCCACCAAGC AGGCTGCTCT GAAAAGCCAT 
TATGCCGACG TGGATCCCGA AAACCAGAAC TTTTTACTTG AATCAAATTT GGGGAAGAAG 
AAGTACGAAA CAGACTTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACGTTC GTGTCAATTT TTTCGCTATA CTCCGTCCAT 
CTCCTCCTCA AGACTGCCAA CGAAGGAGGA TCTTTATTGT ACGAACAGTT GGGACATAAG 
GCGTATGGTC TGGCTGGAAA GCTAGCAGCC TCCGGATCGA TAACCATGCA GAACATTGGG 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTAC CTTTGGTGAT CAAGGCATTA 
ATGAACATTG AAGATACAAA TGGGTTGTGG TATCTGAACG GTGACTATCT GGTCCTTCTG 
GTGTCCCTTG TCCTCATTCT TCCATTGTCA CTGCTGAGAA ATCTAGGATA CTTGGGGTAC 
ACCAGCGGCC TCTCTCTGCT CTGTATGATA TTTTTCCTGA TCGTGGTGAT TTGCAAGAAG 
TTTCAGATCC CTTGCCCCGT GGAAGCTGCT TTGGTGGCCA ACGAAACTGT GAACGGCACC 
TTTACCCAGG CAGCGTTGGC GTTGGCATTC AATAGCACCG CAGACGATGC TTGCAGGCCA 
CGCTATTTCA TCTTCAACTC GCAGACTGTG TATGCAGTAC CCATCCTGAC GTTTTCCTTT 
GTCTGCCATC CCGCTGTTCT TCCCATCTAC GAAGAGCTAA AGAGCCGCAG CCGGAGACGG 
ATGATGAACG TGTCCAAGAT TTCCTTCTTC GCCATGTTTC TGATGTACTT GCTCGCTGCT 
CTCTTTGGAT ACCTGACCTT TTACGGACAC GTGGAATCGG AATTGCTGCA TACCTACTCC 
GAGATCGTGG GGACTGACAT TCTTCTCCTT GTTGTCCGAT TGGCTGTGCT GGTGGCTGTC 
ACCCTCACGG TCCCAGTAGT TATTTTCCCT ATCCGGAGTT CCGTCACTCA CTTACTGTGT 
CCCACAAAAG AGTTCAGCTG GCTCCGGCAC AGCATCATCA CCGTGACCAT CTTGTCCTTC 
ACCAATTTGC TCGTCATCTT TGTCCCCACT ATTAGGGACA TCTTCGGGTT CATTGGGGCG 
TCGGCGGCTG CCATGCTGAT CTTTATCCTC CCGTCTGCCT TCTACATCAA GTTAGTGAAG 
AAGGAACCAA TGAGATCCGT GCAAAAGATT GGGGCTCTGT GTTTTCTCCT GAGTGGCATA 
GTGGTGATGA TTGGAAGCAT GGGCTTGATT GTGCTGGATT GGGTCCACGA TGCCTCCGCT 
GCAGGTGGGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780330.2
CDS	379..1893
Translation	MKKTEMGRFNISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEAALVANETVNGTFTQAALALAFNSTADDACRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWLRHSIITVTILSFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGIVVMIGSMGLIVLDWVHDASAAGGH

Target ORF information:

RefSeq Version	NM_175121.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus solute carrier family 38, member 2 (Slc38a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175121.3

ORF Insert Sequence:

ATGAAGAAGA CCGAAATGGG AAGGTTCAAC ATCTCCCCGG ATGAGGACAG CAGCAGTTAC 
AGCTCCAACA GTGACTTCAA CTACTCATAC CCCACCAAGC AGGCTGCTCT GAAAAGCCAT 
TATGCCGACG TGGATCCCGA AAACCAGAAC TTTTTACTTG AATCAAATTT GGGGAAGAAG 
AAGTACGAAA CAGACTTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACGTTC GTGTCAATTT TTTCGCTATA CTCCGTCCAT 
CTCCTCCTCA AGACTGCCAA CGAAGGAGGA TCTTTATTGT ACGAACAGTT GGGACATAAG 
GCGTATGGTC TGGCTGGAAA GCTAGCAGCC TCCGGATCGA TAACCATGCA GAACATTGGG 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTAC CTTTGGTGAT CAAGGCATTA 
ATGAACATTG AAGATACAAA TGGGTTGTGG TATCTGAACG GTGACTATCT GGTCCTTCTG 
GTGTCCCTTG TCCTCATTCT TCCATTGTCA CTGCTGAGAA ATCTAGGATA CTTGGGGTAC 
ACCAGCGGCC TCTCTCTGCT CTGTATGATA TTTTTCCTGA TCGTGGTGAT TTGCAAGAAG 
TTTCAGATCC CTTGCCCCGT GGAAGCTGCT TTGGTGGCCA ACGAAACTGT GAACGGCACC 
TTTACCCAGG CAGCGTTGGC GTTGGCATTC AATAGCACCG CAGACGATGC TTGCAGGCCA 
CGCTATTTCA TCTTCAACTC GCAGACTGTG TATGCAGTAC CCATCCTGAC GTTTTCCTTT 
GTCTGCCATC CCGCTGTTCT TCCCATCTAC GAAGAGCTAA AGAGCCGCAG CCGGAGACGG 
ATGATGAACG TGTCCAAGAT TTCCTTCTTC GCCATGTTTC TGATGTACTT GCTCGCTGCT 
CTCTTTGGAT ACCTGACCTT TTACGGACAC GTGGAATCGG AATTGCTGCA TACCTACTCC 
GAGATCGTGG GGACTGACAT TCTTCTCCTT GTTGTCCGAT TGGCTGTGCT GGTGGCTGTC 
ACCCTCACGG TCCCAGTAGT TATTTTCCCT ATCCGGAGTT CCGTCACTCA CTTACTGTGT 
CCCACAAAAG AGTTCAGCTG GCTCCGGCAC AGCATCATCA CCGTGACCAT CTTGTCCTTC 
ACCAATTTGC TCGTCATCTT TGTCCCCACT ATTAGGGACA TCTTCGGGTT CATTGGGGCG 
TCGGCGGCTG CCATGCTGAT CTTTATCCTC CCGTCTGCCT TCTACATCAA GTTAGTGAAG 
AAGGAACCAA TGAGATCCGT GCAAAAGATT GGGGCTCTGT GTTTTCTCCT GAGTGGCATA 
GTGGTGATGA TTGGAAGCAT GGGCTTGATT GTGCTGGATT GGGTCCACGA TGCCTCCGCT 
GCAGGTGGGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc38a2 ( NM_175121.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780330.2 Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 1, mRNA.

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CloneID	OMu04878
Clone ID Related Accession (Same CDS sequence)	NM_175121.3 , NM_175121.4
Accession Version	NM_175121.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	sodium-coupled neutral amino acid transporter 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109201.12. On Sep 22, 2017 this sequence version replaced NM_175121.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048178.1, SRR1660821.9254.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGAAGAAGA CCGAAATGGG AAGGTTCAAC ATCTCCCCGG ATGAGGACAG CAGCAGTTAC 
AGCTCCAACA GTGACTTCAA CTACTCATAC CCCACCAAGC AGGCTGCTCT GAAAAGCCAT 
TATGCCGACG TGGATCCCGA AAACCAGAAC TTTTTACTTG AATCAAATTT GGGGAAGAAG 
AAGTACGAAA CAGACTTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACGTTC GTGTCAATTT TTTCGCTATA CTCCGTCCAT 
CTCCTCCTCA AGACTGCCAA CGAAGGAGGA TCTTTATTGT ACGAACAGTT GGGACATAAG 
GCGTATGGTC TGGCTGGAAA GCTAGCAGCC TCCGGATCGA TAACCATGCA GAACATTGGG 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTAC CTTTGGTGAT CAAGGCATTA 
ATGAACATTG AAGATACAAA TGGGTTGTGG TATCTGAACG GTGACTATCT GGTCCTTCTG 
GTGTCCCTTG TCCTCATTCT TCCATTGTCA CTGCTGAGAA ATCTAGGATA CTTGGGGTAC 
ACCAGCGGCC TCTCTCTGCT CTGTATGATA TTTTTCCTGA TCGTGGTGAT TTGCAAGAAG 
TTTCAGATCC CTTGCCCCGT GGAAGCTGCT TTGGTGGCCA ACGAAACTGT GAACGGCACC 
TTTACCCAGG CAGCGTTGGC GTTGGCATTC AATAGCACCG CAGACGATGC TTGCAGGCCA 
CGCTATTTCA TCTTCAACTC GCAGACTGTG TATGCAGTAC CCATCCTGAC GTTTTCCTTT 
GTCTGCCATC CCGCTGTTCT TCCCATCTAC GAAGAGCTAA AGAGCCGCAG CCGGAGACGG 
ATGATGAACG TGTCCAAGAT TTCCTTCTTC GCCATGTTTC TGATGTACTT GCTCGCTGCT 
CTCTTTGGAT ACCTGACCTT TTACGGACAC GTGGAATCGG AATTGCTGCA TACCTACTCC 
GAGATCGTGG GGACTGACAT TCTTCTCCTT GTTGTCCGAT TGGCTGTGCT GGTGGCTGTC 
ACCCTCACGG TCCCAGTAGT TATTTTCCCT ATCCGGAGTT CCGTCACTCA CTTACTGTGT 
CCCACAAAAG AGTTCAGCTG GCTCCGGCAC AGCATCATCA CCGTGACCAT CTTGTCCTTC 
ACCAATTTGC TCGTCATCTT TGTCCCCACT ATTAGGGACA TCTTCGGGTT CATTGGGGCG 
TCGGCGGCTG CCATGCTGAT CTTTATCCTC CCGTCTGCCT TCTACATCAA GTTAGTGAAG 
AAGGAACCAA TGAGATCCGT GCAAAAGATT GGGGCTCTGT GTTTTCTCCT GAGTGGCATA 
GTGGTGATGA TTGGAAGCAT GGGCTTGATT GTGCTGGATT GGGTCCACGA TGCCTCCGCT 
GCAGGTGGGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780330.2
CDS	409..1923
Translation	MKKTEMGRFNISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEAALVANETVNGTFTQAALALAFNSTADDACRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWLRHSIITVTILSFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGIVVMIGSMGLIVLDWVHDASAAGGH

Target ORF information:

RefSeq Version	NM_175121.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 38, member 2 (Slc38a2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175121.4

ORF Insert Sequence:

ATGAAGAAGA CCGAAATGGG AAGGTTCAAC ATCTCCCCGG ATGAGGACAG CAGCAGTTAC 
AGCTCCAACA GTGACTTCAA CTACTCATAC CCCACCAAGC AGGCTGCTCT GAAAAGCCAT 
TATGCCGACG TGGATCCCGA AAACCAGAAC TTTTTACTTG AATCAAATTT GGGGAAGAAG 
AAGTACGAAA CAGACTTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACGTTC GTGTCAATTT TTTCGCTATA CTCCGTCCAT 
CTCCTCCTCA AGACTGCCAA CGAAGGAGGA TCTTTATTGT ACGAACAGTT GGGACATAAG 
GCGTATGGTC TGGCTGGAAA GCTAGCAGCC TCCGGATCGA TAACCATGCA GAACATTGGG 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTAC CTTTGGTGAT CAAGGCATTA 
ATGAACATTG AAGATACAAA TGGGTTGTGG TATCTGAACG GTGACTATCT GGTCCTTCTG 
GTGTCCCTTG TCCTCATTCT TCCATTGTCA CTGCTGAGAA ATCTAGGATA CTTGGGGTAC 
ACCAGCGGCC TCTCTCTGCT CTGTATGATA TTTTTCCTGA TCGTGGTGAT TTGCAAGAAG 
TTTCAGATCC CTTGCCCCGT GGAAGCTGCT TTGGTGGCCA ACGAAACTGT GAACGGCACC 
TTTACCCAGG CAGCGTTGGC GTTGGCATTC AATAGCACCG CAGACGATGC TTGCAGGCCA 
CGCTATTTCA TCTTCAACTC GCAGACTGTG TATGCAGTAC CCATCCTGAC GTTTTCCTTT 
GTCTGCCATC CCGCTGTTCT TCCCATCTAC GAAGAGCTAA AGAGCCGCAG CCGGAGACGG 
ATGATGAACG TGTCCAAGAT TTCCTTCTTC GCCATGTTTC TGATGTACTT GCTCGCTGCT 
CTCTTTGGAT ACCTGACCTT TTACGGACAC GTGGAATCGG AATTGCTGCA TACCTACTCC 
GAGATCGTGG GGACTGACAT TCTTCTCCTT GTTGTCCGAT TGGCTGTGCT GGTGGCTGTC 
ACCCTCACGG TCCCAGTAGT TATTTTCCCT ATCCGGAGTT CCGTCACTCA CTTACTGTGT 
CCCACAAAAG AGTTCAGCTG GCTCCGGCAC AGCATCATCA CCGTGACCAT CTTGTCCTTC 
ACCAATTTGC TCGTCATCTT TGTCCCCACT ATTAGGGACA TCTTCGGGTT CATTGGGGCG 
TCGGCGGCTG CCATGCTGAT CTTTATCCTC CCGTCTGCCT TCTACATCAA GTTAGTGAAG 
AAGGAACCAA TGAGATCCGT GCAAAAGATT GGGGCTCTGT GTTTTCTCCT GAGTGGCATA 
GTGGTGATGA TTGGAAGCAT GGGCTTGATT GTGCTGGATT GGGTCCACGA TGCCTCCGCT 
GCAGGTGGGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Scientific reports740692(2017 Jan)
Kurogi S,Sekimoto T,Funamoto T,Ota T,Nakamura S,Nagai T,Nakahara M,Yoshinobu K,Araki K,Araki M,Chosa E

Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport.
Brain : a journal of neurology139(Pt 12)3109-3120(2016 Dec)
Moen MN,Fj?r R,Hamdani EH,Laerdahl JK,Menchini RJ,Vigeland MD,Sheng Y,Undlien DE,Hassel B,Salih MA,El Khashab HY,Selmer KK,Chaudhry FA

Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.
Mechanisms of development14132-9(2016 08)
Tan BS,Rathjen PD,Harvey AJ,Gardner DK,Rathjen J

A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.
Nature communications67940(2015 Aug)
Uno K,Yamada T,Ishigaki Y,Imai J,Hasegawa Y,Sawada S,Kaneko K,Ono H,Asano T,Oka Y,Katagiri H

Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity.
The Journal of biological chemistry290(29)17822-37(2015 Jul)
Krokowski D,Jobava R,Guan BJ,Farabaugh K,Wu J,Majumder M,Bianchi MG,Snider MD,Bussolati O,Hatzoglou M

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Slc38a2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム