Riok3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Riok3
Entrez Gene ID	66878
Full Name	RIO kinase 3
Synonyms	1200013N13Rik,D18Ertd331e,E130306C24Rik,Sudd
General protein information	Preferred Names RIO kinase 3 Names serine/threonine-protein kinase RIO3 sudD, suppressor of bimD6 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18 A1\|18 6.15 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_017317969.1	XP_017173458.1	serine/threonine-protein kinase RIO3 isoform X1
NM_024182.4	NP_077144.2	serine/threonine-protein kinase RIO3

Pathways from BioSystems

Homologies

Homo sapiens (human)	RIOK3	NP_003822.2
Drosophila melanogaster (fruit fly)	CG3008	NP_608871.1
Mus musculus (house mouse)	Riok3	NP_077144.2
Gallus gallus (chicken)	RIOK3	XP_419160.2
Xenopus tropicalis (tropical clawed frog)	riok3	NP_001004996.1
Pan troglodytes (chimpanzee)	RIOK3	XP_523888.2
Bos taurus (cattle)	RIOK3	NP_001069304.1
Rattus norvegicus (Norway rat)	Riok3	NP_001101893.1
Caenorhabditis elegans (roundworm)	riok-3	NP_499173.1
Canis lupus familiaris (dog)	RIOK3	XP_003639235.1
Danio rerio (zebrafish)	riok3	NP_001003614.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009993	XP_319133.4

Gene Ontology
Bibliography

Related articles in PubMed

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
Zhang L, Flygare J, Wong P, Lim B, Lodish HF
Genes & development25(2)119-24(2011 Jan)

Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.
Darakhshan F, Badie C, Moody J, Coster M, Finnon R, Finnon P, Edwards AA, Szluinska M, Skidmore CJ, Yoshida K, Ullrich R, Cox R, Bouffler SD
Carcinogenesis27(2)311-8(2006 Feb)

The RIO kinases: an atypical protein kinase family required for ribosome biogenesis and cell cycle progression.
LaRonde-LeBlanc N, Wlodawer A
Biochimica et biophysica acta1754(1-2)14-24(2005 Dec)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

down-regulation of miR-191 is essential for erythroid chromatin condensation and enucleation by allowing up-regulation of Riok3 and Mxi1
Title: miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.

The following Riok3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Riok3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01082	NM_024182.4 Latest version!	Mus musculus RIO kinase 3 (Riok3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu79830	XM_017317969.1 Latest version!	Mus musculus RIO kinase 3 (Riok3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Riok3 ( NM_024182.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077144.2 Mus musculus RIO kinase 3 (Riok3), mRNA.

Price & Availability↑

CloneID	OMu01082
Clone ID Related Accession (Same CDS sequence)	NM_024182.4
Accession Version	NM_024182.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase RIO3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK147074.1. On Apr 6, 2007 this sequence version replaced NM_024182.3. ##Evidence-Data-START## Transcript exon combination :: AK147074.1, AK004748.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGATCTGG TCGGAGTGTC TTCGCCTGAG CCAGGGCCCG CAGCAGCTTG GGGACCCAGT 
AAGTGCCCAT GGGCTACCCC TCAAAACACA GTATCCTGTT CACTGACCGA GGTGATGAGT 
GAGGAGCTGG CTAAAGAGCT GCAGTTGGAA GAAGAAGCGG CTGCTTTCCC TGAAGTTGTT 
GTTGCTGAAG GACCATTCAT TTCTGGAGAA AACATTGACA CTTCCAGTGA CCTAATGCTG 
GCTCAGATGC TACAGATGGA ATTTGACAGA GAATATGATG CACAGCTTAG GCGTGAGGAA 
AAGAAGTTCA ATGGTGATAG CAAAGTTTCC ATTTCGTTTG AAAACTATCG CAAAGTTCAT 
CCTTTTGAAG ACAGTGACAG CTCTGAAGAC GAGGTTGACT GGCAGGACAC TCGAGACGAT 
CCCTACAGAC CAGCAAAGCC AATTCCTACT CCCAAAAAGG GTTTTATTGG AAAAGGAAAA 
GACATCACCA CCAAGCATGA TGAAGTAGTA TGTGGAAGGA AGAACACAGC AAGAATGGAA 
AATTTTGCCC CTGGCTTTCA GGTAGGGGAT GGAATTGGAA TGGATTTGAA ACTATCCAAC 
CACGTTTTTA ATGCCTTAAA ACAACACGCC TACTCAGAAG AGCGTCGGAG TGCCCGTCTA 
CACGAGAAGA AGGAACATTC TACCGCTGAA AAAGCAGTTG ATCCTAAGAC ACGCTTACTT 
ATGTATAAAA TGGTCAACTC TGGAATGTTG GAGACAATCA CTGGCTGTAT TAGTACAGGA 
AAGGAATCTG TTGTCTTTCA TGCATATGGA GGGAGCCTGG AGGATGAAAA GGAAGATGGT 
AAAGCTATAC CAACAGAATG TGCCATCAAG GTATTTAAAA CAACCCTTAA TGAGTTTAAG 
AATCGTGACA AGTACATTAA AGATGATTTC AGGTTTAAAG ATCGCTTCAG TAAACTAAAT 
CCACGTAAGA TCATCCGCAT GTGGGCAGAG AAAGAAATGC ACAATCTTAC AAGAATGCAG 
AAGGCTGGAA TTCCTTGTCC AACAGTTGTA CTGCTTAAGA AGCACATTTT AGTTATGTCT 
TTCATTGGCC ATGATCAAGT TCCAGCCCCT AAATTAAAAG AAGTAAAGCT TAGTAATGAA 
GAAATGAAAG ATGCCTACTA TCAGACTCTT CATTTGATGC AGCAATTATA TAACGAATGT 
ACCCTTGTGC ATGCTGACCT CAGCGAGTAT AACATGTTGT GGCATGCTGG GAAGGTCTGG 
TTGATTGACG TCAGTCAGTC GGTAGAGCCA ACCCATCCTC ATGGCCTGGA GTTCTTATTC 
CGTGACTGTA GGAATGTTTC ACAGTTCTTC CAGAAAGGAG GAGTAACGGA AGCCCTCAAT 
GAACGGGAGC TGTTCAATGC TGTTTCTGGC CTGAACATCT CGGCAGACAA TGAAGCTGAT 
TTCTTAGCTG AGATAGAAGC TTTGGAGAAG ATGAATGAAG ATCACATTCA GAAGAACGGG 
AGGAAAGCAG CCTCGTTTCT GAAAGATGAT GGAAGCCCAC CTGTGCTGTC TGCCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077144.2
CDS	62..1621
Translation	MDLVGVSSPEPGPAAAWGPSKCPWATPQNTVSCSLTEVMSEELAKELQLEEEAAAFPEVVVAEGPFISGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFEDSDSSEDEVDWQDTRDDPYRPAKPIPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMKDAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAVSGLNISADNEADFLAEIEALEKMNEDHIQKNGRKAASFLKDDGSPPVLSAD

Target ORF information:

RefSeq Version	NM_024182.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus RIO kinase 3 (Riok3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024182.4

ORF Insert Sequence:

ATGGATCTGG TCGGAGTGTC TTCGCCTGAG CCAGGGCCCG CAGCAGCTTG GGGACCCAGT 
AAGTGCCCAT GGGCTACCCC TCAAAACACA GTATCCTGTT CACTGACCGA GGTGATGAGT 
GAGGAGCTGG CTAAAGAGCT GCAGTTGGAA GAAGAAGCGG CTGCTTTCCC TGAAGTTGTT 
GTTGCTGAAG GACCATTCAT TTCTGGAGAA AACATTGACA CTTCCAGTGA CCTAATGCTG 
GCTCAGATGC TACAGATGGA ATTTGACAGA GAATATGATG CACAGCTTAG GCGTGAGGAA 
AAGAAGTTCA ATGGTGATAG CAAAGTTTCC ATTTCGTTTG AAAACTATCG CAAAGTTCAT 
CCTTTTGAAG ACAGTGACAG CTCTGAAGAC GAGGTTGACT GGCAGGACAC TCGAGACGAT 
CCCTACAGAC CAGCAAAGCC AATTCCTACT CCCAAAAAGG GTTTTATTGG AAAAGGAAAA 
GACATCACCA CCAAGCATGA TGAAGTAGTA TGTGGAAGGA AGAACACAGC AAGAATGGAA 
AATTTTGCCC CTGGCTTTCA GGTAGGGGAT GGAATTGGAA TGGATTTGAA ACTATCCAAC 
CACGTTTTTA ATGCCTTAAA ACAACACGCC TACTCAGAAG AGCGTCGGAG TGCCCGTCTA 
CACGAGAAGA AGGAACATTC TACCGCTGAA AAAGCAGTTG ATCCTAAGAC ACGCTTACTT 
ATGTATAAAA TGGTCAACTC TGGAATGTTG GAGACAATCA CTGGCTGTAT TAGTACAGGA 
AAGGAATCTG TTGTCTTTCA TGCATATGGA GGGAGCCTGG AGGATGAAAA GGAAGATGGT 
AAAGCTATAC CAACAGAATG TGCCATCAAG GTATTTAAAA CAACCCTTAA TGAGTTTAAG 
AATCGTGACA AGTACATTAA AGATGATTTC AGGTTTAAAG ATCGCTTCAG TAAACTAAAT 
CCACGTAAGA TCATCCGCAT GTGGGCAGAG AAAGAAATGC ACAATCTTAC AAGAATGCAG 
AAGGCTGGAA TTCCTTGTCC AACAGTTGTA CTGCTTAAGA AGCACATTTT AGTTATGTCT 
TTCATTGGCC ATGATCAAGT TCCAGCCCCT AAATTAAAAG AAGTAAAGCT TAGTAATGAA 
GAAATGAAAG ATGCCTACTA TCAGACTCTT CATTTGATGC AGCAATTATA TAACGAATGT 
ACCCTTGTGC ATGCTGACCT CAGCGAGTAT AACATGTTGT GGCATGCTGG GAAGGTCTGG 
TTGATTGACG TCAGTCAGTC GGTAGAGCCA ACCCATCCTC ATGGCCTGGA GTTCTTATTC 
CGTGACTGTA GGAATGTTTC ACAGTTCTTC CAGAAAGGAG GAGTAACGGA AGCCCTCAAT 
GAACGGGAGC TGTTCAATGC TGTTTCTGGC CTGAACATCT CGGCAGACAA TGAAGCTGAT 
TTCTTAGCTG AGATAGAAGC TTTGGAGAAG ATGAATGAAG ATCACATTCA GAAGAACGGG 
AGGAAAGCAG CCTCGTTTCT GAAAGATGAT GGAAGCCCAC CTGTGCTGTC TGCCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Riok3 ( XM_017317969.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173458.1 Mus musculus RIO kinase 3 (Riok3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OMu79830
Clone ID Related Accession (Same CDS sequence)	XM_017317969.1
Accession Version	XM_017317969.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase RIO3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAGCC AATCAGAAGT GAGATCCTTA GTATACAGGG CGGAAAAGAA GTGGTCCAGT 
TCCGGCCGCG GCCGCCGCCG CCGCCGCCGC CATCTGTCAC CTCACCTCCG GCACCGGCAG 
CGGGTTGCCC GTGCCCCGCC CGTGTCCTCG GCGGAGCCCT TTCTTCCTCT TGTCACCTCT 
CGACTCTGTT CTCGTCTCTG CCTTCTTCCC GGAATGGATC TGGTCGGAGT GTCTTCGCCT 
GAGCCAGGGC CCGCAGCAGC TTGGGGACCC AGTAAGTGCC CATGGGCTAC CCCTCAAAAC 
ACAGTATCCT GTTCACTGAC CGAGGTGATG AGTGAGGAGC TGGCTAAAGA GCTGCAGTTG 
GAAGAAGAAG CGGCTGCTTT CCCTGAAGTT GTTGTTGCTG AAGGACCATT CATTTCTGGA 
GAAAACATTG ACACTTCCAG TGACCTAATG CTGGCTCAGA TGCTACAGAT GGAATTTGAC 
AGAGAATATG ATGCACAGCT TAGGCGTGAG GAAAAGAAGT TCAATGGTGA TAGCAAAGTT 
TCCATTTCGT TTGAAAACTA TCGCAAAGTT CATCCTTTTG AAGACAGTGA CAGCTCTGAA 
GACGAGGTTG ACTGGCAGGA CACTCGAGAC GATCCCTACA GACCAGCAAA GCCAATTCCT 
ACTCCCAAAA AGGGTTTTAT TGGAAAAGGA AAAGACATCA CCACCAAGCA TGATGAAGTA 
GTATGTGGAA GGAAGAACAC AGCAAGAATG GAAAATTTTG CCCCTGGCTT TCAGGTAGGG 
GATGGAATTG GAATGGATTT GAAACTATCC AACCACGTTT TTAATGCCTT AAAACAACAC 
GCCTACTCAG AAGAGCGTCG GAGTGCCCGT CTACACGAGA AGAAGGAACA TTCTACCGCT 
CCTGGAGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173458.1
CDS	2474..3385
Translation	MNSQSEVRSLVYRAEKKWSSSGRGRRRRRRHLSPHLRHRQRVARAPPVSSAEPFLPLVTSRLCSRLCLLPGMDLVGVSSPEPGPAAAWGPSKCPWATPQNTVSCSLTEVMSEELAKELQLEEEAAAFPEVVVAEGPFISGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFEDSDSSEDEVDWQDTRDDPYRPAKPIPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAPGG

Target ORF information:

RefSeq Version	XM_017317969.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RIO kinase 3 (Riok3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017317969.1

ORF Insert Sequence:

ATGAACAGCC AATCAGAAGT GAGATCCTTA GTATACAGGG CGGAAAAGAA GTGGTCCAGT 
TCCGGCCGCG GCCGCCGCCG CCGCCGCCGC CATCTGTCAC CTCACCTCCG GCACCGGCAG 
CGGGTTGCCC GTGCCCCGCC CGTGTCCTCG GCGGAGCCCT TTCTTCCTCT TGTCACCTCT 
CGACTCTGTT CTCGTCTCTG CCTTCTTCCC GGAATGGATC TGGTCGGAGT GTCTTCGCCT 
GAGCCAGGGC CCGCAGCAGC TTGGGGACCC AGTAAGTGCC CATGGGCTAC CCCTCAAAAC 
ACAGTATCCT GTTCACTGAC CGAGGTGATG AGTGAGGAGC TGGCTAAAGA GCTGCAGTTG 
GAAGAAGAAG CGGCTGCTTT CCCTGAAGTT GTTGTTGCTG AAGGACCATT CATTTCTGGA 
GAAAACATTG ACACTTCCAG TGACCTAATG CTGGCTCAGA TGCTACAGAT GGAATTTGAC 
AGAGAATATG ATGCACAGCT TAGGCGTGAG GAAAAGAAGT TCAATGGTGA TAGCAAAGTT 
TCCATTTCGT TTGAAAACTA TCGCAAAGTT CATCCTTTTG AAGACAGTGA CAGCTCTGAA 
GACGAGGTTG ACTGGCAGGA CACTCGAGAC GATCCCTACA GACCAGCAAA GCCAATTCCT 
ACTCCCAAAA AGGGTTTTAT TGGAAAAGGA AAAGACATCA CCACCAAGCA TGATGAAGTA 
GTATGTGGAA GGAAGAACAC AGCAAGAATG GAAAATTTTG CCCCTGGCTT TCAGGTAGGG 
GATGGAATTG GAATGGATTT GAAACTATCC AACCACGTTT TTAATGCCTT AAAACAACAC 
GCCTACTCAG AAGAGCGTCG GAGTGCCCGT CTACACGAGA AGAAGGAACA TTCTACCGCT 
CCTGGAGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
Genes & development25(2)119-24(2011 Jan)
Zhang L,Flygare J,Wong P,Lim B,Lodish HF

Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.
Carcinogenesis27(2)311-8(2006 Feb)
Darakhshan F,Badie C,Moody J,Coster M,Finnon R,Finnon P,Edwards AA,Szluinska M,Skidmore CJ,Yoshida K,Ullrich R,Cox R,Bouffler SD

The RIO kinases: an atypical protein kinase family required for ribosome biogenesis and cell cycle progression.
Biochimica et biophysica acta1754(1-2)14-24(2005 Dec)
LaRonde-LeBlanc N,Wlodawer A

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Riok3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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