Atg4b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atg4b
Entrez Gene ID	66615
Full Name	autophagy related 4B, cysteine peptidase
Synonyms	2510009N07Rik,AW048066,Apg4b,Atg4bl,Autl1
General protein information	Preferred Names autophagy related 4B, cysteine peptidase Names cysteine protease ATG4B APG4 (ATG4) autophagy-related homolog B AUT-like 1, cysteine endopeptidase autophagin 1 autophagy-related 4B autophagy-related cysteine endopeptidase 1 autophagy-related protein 4 homolog B cysteine protease involved in autophagy APG4-B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 D

mRNA and Protein(s)

mRNA	Protein	Name
XM_006529793.3	XP_006529856.1	cysteine protease ATG4B isoform X1
XM_006529793.2	XP_006529856.1	cysteine protease ATG4B isoform X1
NM_174874.4	NP_777363.1	cysteine protease ATG4B isoform 1
NM_174874.3	NP_777363.1	cysteine protease ATG4B
NM_001368266.1	NP_001355195.1	cysteine protease ATG4B isoform 2

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	atg4	NP_594771.1
Rattus norvegicus (Norway rat)	Atg4b	NP_001020882.1
Magnaporthe oryzae (rice blast fungus)	MGG_03580	XP_003716330.1
Homo sapiens (human)	ATG4B	NP_037457.3
Danio rerio (zebrafish)	atg4b	NP_001082821.1
Xenopus tropicalis (tropical clawed frog)	atg4b	NP_001072464.1
	LOC717813	XP_002799164.1
Gallus gallus (chicken)	ATG4B	NP_998738.1
Pan troglodytes (chimpanzee)	ATG4B	XP_003950065.1
Canis lupus familiaris (dog)	ATG4B	XP_005636054.1
Bos taurus (cattle)	ATG4B	NP_001001170.1
Mus musculus (house mouse)	Atg4b	NP_777363.1
Neurospora crassa	NCU02433	XP_959438.1

Gene Ontology
Bibliography

Related articles in PubMed

Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.
Ramkumar A, Murthy D, Raja DA, Singh A, Krishnan A, Khanna S, Vats A, Thukral L, Sharma P, Sivasubbu S, Rani R, Natarajan VT, Gokhale RS
Autophagy13(8)1331-1347(2017 Aug)

ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Skytte Rasmussen M, Mouilleron S, Kumar Shrestha B, Wirth M, Lee R, Bowitz Larsen K, Abudu Princely Y, O'Reilly N, Sj?ttem E, Tooze SA, Lamark T, Johansen T
Autophagy13(5)834-853(2017 May)

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.
Lu Q, Yokoyama CC, Williams JW, Baldridge MT, Jin X, DesRochers B, Bricker T, Wilen CB, Bagaitkar J, Loginicheva E, Sergushichev A, Kreamalmeyer D, Keller BC, Zhao Y, Kambal A, Green DR, Martinez J, Dinauer MC, Holtzman MJ, Crouch EC, Beatty W, Boon AC, Zhang H, Randolph GJ, Artyomov MN, Virgin HW
Cell host & microbe19(1)102-13(2016 Jan)

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.
Kimmey JM, Huynh JP, Weiss LA, Park S, Kambal A, Debnath J, Virgin HW, Stallings CL
Nature528(7583)565-9(2015 Dec)

MicroRNA-34a Suppresses Autophagy in Tubular Epithelial Cells in Acute Kidney Injury.
Liu XJ, Hong Q, Wang Z, Yu YY, Zou X, Xu LH
American journal of nephrology42(2)168-75(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these findings demonstrate a role for Ser-383 and Ser-392 phosphorylation of ATG4B in control of autophagy.
Title: ATG4B (Autophagin-1) phosphorylation modulates autophagy.

the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis
Title: Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis.

REDD1/TXNIP complex expression is sufficient to induce reactive oxygen species, suppress ATG4B activity and activate autophagy.
Title: A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.

miR-34a might regulate the autophagic activity and can cause injury in ischemia reperfusion injured renal tubular epithelial cells (RTEC) via targeting Atg4B. Atg4B knockdown inhibited autophagy in RTECs.
Title: MicroRNA-34a Suppresses Autophagy in Tubular Epithelial Cells in Acute Kidney Injury.

mTOR inhibition alleviates Huntington's disease progression by inducing Atg4b-dependent autophagic flux.
Title: Atg4b-dependent autophagic flux alleviates Huntington's disease progression.

The following Atg4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atg4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04709	NM_174874.4 Latest version!	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu84633	NM_001368266.1 Latest version!	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu28374	XM_006529793.3 Latest version!	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu28374	XM_006529793.2	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu04709	NM_174874.3	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atg4b ( NM_174874.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_777363.1 Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04709
Clone ID Related Accession (Same CDS sequence)	NM_174874.4 , NM_174874.3
Accession Version	NM_174874.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Mus musculus(house mouse)
Product	cysteine protease ATG4B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC162891.6 and AK031570.1. On Feb 1, 2019 this sequence version replaced NM_174874.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK031570.1, AK144239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGGGGGAA CTGGCCCTAC TTCAGACACA GGCTGGGGTT GCATGCTTCG GTGTGGACAG 
ATGATCTTTG CCCAGGCCCT GGTATGCCGG CACTTAGGTC GAGATTGGAG GTGGACTCAG 
CGGAAGAGGC AGCCTGACAG CTACTTTAAT GTCCTCAATG CTTTCCTCGA CAGGAAGGAC 
AGCTACTATT CCATCCATCA GATAGCGCAA ATGGGAGTTG GCGAAGGCAA GTCTATAGGC 
CAGTGGTACG GGCCGAACAC TGTTGCCCAG GTCCTCAAGA AACTTGCTGT ATTCGACACA 
TGGAGTTCCT TGGCTGTTCA CATAGCAATG GACAACACTG TGGTGATGGA GGAAATCAGA 
AGGTTATGCA GGGCCAACCT TCCCTGTGTT GGGGCGGCTG CACTTCCTAC TGATTCAGAG 
AGGCACTGTA ATGGGTTCCC TGCTGGAGCT GAAGTCACCA ACAGGCCATC GGCTTGGAGA 
CCACTAGTGC TTCTCATCCC TCTCCGCCTG GGACTGACAG ACATCAATGA GGCCTATGTG 
GAGACGCTGA AGCACTGTTT CATGATGCCC CAGTCCCTGG GTGTTATTGG AGGGAAGCCC 
AACAGTGCCC ACTACTTTAT TGGCTATGTT GGGGAGGAGC TCATCTATCT GGACCCCCAC 
ACTACACAGC CTGCAGTGGA GCTGACTGAC AGCTGCTTCA TCCCCGACGA GAGCTTCCAC 
TGCCAGCACC CTCCCTCTAG GATGGGCATT GGAGAGCTTG ACCCGTCCAT TGCTGTGGGG 
TTTTTCTGTA AGACGGAGGA AGACTTTAAC GACTGGTGTC AGCAAGTCAA AAAGCTATCC 
CAGCTTGGAG GTGCCCTGCC CATGTTTGAG CTGGTGGAAC AGCAGCCTTC CCATCTGGCC 
TGCCAGGATG TCCTGAACCT GTCCCTAGAC TCTTCTGATG TAGAGAGACT GGAGAGGTTT 
TTTGACTCTG AGGATGAAGA CTTTGAAATC TTATCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777363.1
CDS	141..1322
Translation	MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRRNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL

Target ORF information:

RefSeq Version	NM_174874.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174874.4

ORF Insert Sequence:

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGGGGGAA CTGGCCCTAC TTCAGACACA GGCTGGGGTT GCATGCTTCG GTGTGGACAG 
ATGATCTTTG CCCAGGCCCT GGTATGCCGG CACTTAGGTC GAGATTGGAG GTGGACTCAG 
CGGAAGAGGC AGCCTGACAG CTACTTTAAT GTCCTCAATG CTTTCCTCGA CAGGAAGGAC 
AGCTACTATT CCATCCATCA GATAGCGCAA ATGGGAGTTG GCGAAGGCAA GTCTATAGGC 
CAGTGGTACG GGCCGAACAC TGTTGCCCAG GTCCTCAAGA AACTTGCTGT ATTCGACACA 
TGGAGTTCCT TGGCTGTTCA CATAGCAATG GACAACACTG TGGTGATGGA GGAAATCAGA 
AGGTTATGCA GGGCCAACCT TCCCTGTGTT GGGGCGGCTG CACTTCCTAC TGATTCAGAG 
AGGCACTGTA ATGGGTTCCC TGCTGGAGCT GAAGTCACCA ACAGGCCATC GGCTTGGAGA 
CCACTAGTGC TTCTCATCCC TCTCCGCCTG GGACTGACAG ACATCAATGA GGCCTATGTG 
GAGACGCTGA AGCACTGTTT CATGATGCCC CAGTCCCTGG GTGTTATTGG AGGGAAGCCC 
AACAGTGCCC ACTACTTTAT TGGCTATGTT GGGGAGGAGC TCATCTATCT GGACCCCCAC 
ACTACACAGC CTGCAGTGGA GCTGACTGAC AGCTGCTTCA TCCCCGACGA GAGCTTCCAC 
TGCCAGCACC CTCCCTCTAG GATGGGCATT GGAGAGCTTG ACCCGTCCAT TGCTGTGGGG 
TTTTTCTGTA AGACGGAGGA AGACTTTAAC GACTGGTGTC AGCAAGTCAA AAAGCTATCC 
CAGCTTGGAG GTGCCCTGCC CATGTTTGAG CTGGTGGAAC AGCAGCCTTC CCATCTGGCC 
TGCCAGGATG TCCTGAACCT GTCCCTAGAC TCTTCTGATG TAGAGAGACT GGAGAGGTTT 
TTTGACTCTG AGGATGAAGA CTTTGAAATC TTATCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atg4b ( NM_174874.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_777363.1 Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), mRNA.

Price & Availability↑

CloneID	OMu04709
Clone ID Related Accession (Same CDS sequence)	NM_174874.4 , NM_174874.3
Accession Version	NM_174874.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-10
Organism	Mus musculus(house mouse)
Product	cysteine protease ATG4B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC162891.6. On May 2, 2007 this sequence version replaced NM_174874.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK031570.1, SRR1660823.156747.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGGGGGAA CTGGCCCTAC TTCAGACACA GGCTGGGGTT GCATGCTTCG GTGTGGACAG 
ATGATCTTTG CCCAGGCCCT GGTATGCCGG CACTTAGGTC GAGATTGGAG GTGGACTCAG 
CGGAAGAGGC AGCCTGACAG CTACTTTAAT GTCCTCAATG CTTTCCTCGA CAGGAAGGAC 
AGCTACTATT CCATCCATCA GATAGCGCAA ATGGGAGTTG GCGAAGGCAA GTCTATAGGC 
CAGTGGTACG GGCCGAACAC TGTTGCCCAG GTCCTCAAGA AACTTGCTGT ATTCGACACA 
TGGAGTTCCT TGGCTGTTCA CATAGCAATG GACAACACTG TGGTGATGGA GGAAATCAGA 
AGGTTATGCA GGGCCAACCT TCCCTGTGTT GGGGCGGCTG CACTTCCTAC TGATTCAGAG 
AGGCACTGTA ATGGGTTCCC TGCTGGAGCT GAAGTCACCA ACAGGCCATC GGCTTGGAGA 
CCACTAGTGC TTCTCATCCC TCTCCGCCTG GGACTGACAG ACATCAATGA GGCCTATGTG 
GAGACGCTGA AGCACTGTTT CATGATGCCC CAGTCCCTGG GTGTTATTGG AGGGAAGCCC 
AACAGTGCCC ACTACTTTAT TGGCTATGTT GGGGAGGAGC TCATCTATCT GGACCCCCAC 
ACTACACAGC CTGCAGTGGA GCTGACTGAC AGCTGCTTCA TCCCCGACGA GAGCTTCCAC 
TGCCAGCACC CTCCCTCTAG GATGGGCATT GGAGAGCTTG ACCCGTCCAT TGCTGTGGGG 
TTTTTCTGTA AGACGGAGGA AGACTTTAAC GACTGGTGTC AGCAAGTCAA AAAGCTATCC 
CAGCTTGGAG GTGCCCTGCC CATGTTTGAG CTGGTGGAAC AGCAGCCTTC CCATCTGGCC 
TGCCAGGATG TCCTGAACCT GTCCCTAGAC TCTTCTGATG TAGAGAGACT GGAGAGGTTT 
TTTGACTCTG AGGATGAAGA CTTTGAAATC TTATCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777363.1
CDS	13..1194
Translation	MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRRNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL

Target ORF information:

RefSeq Version	NM_174874.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174874.3

ORF Insert Sequence:

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGGGGGAA CTGGCCCTAC TTCAGACACA GGCTGGGGTT GCATGCTTCG GTGTGGACAG 
ATGATCTTTG CCCAGGCCCT GGTATGCCGG CACTTAGGTC GAGATTGGAG GTGGACTCAG 
CGGAAGAGGC AGCCTGACAG CTACTTTAAT GTCCTCAATG CTTTCCTCGA CAGGAAGGAC 
AGCTACTATT CCATCCATCA GATAGCGCAA ATGGGAGTTG GCGAAGGCAA GTCTATAGGC 
CAGTGGTACG GGCCGAACAC TGTTGCCCAG GTCCTCAAGA AACTTGCTGT ATTCGACACA 
TGGAGTTCCT TGGCTGTTCA CATAGCAATG GACAACACTG TGGTGATGGA GGAAATCAGA 
AGGTTATGCA GGGCCAACCT TCCCTGTGTT GGGGCGGCTG CACTTCCTAC TGATTCAGAG 
AGGCACTGTA ATGGGTTCCC TGCTGGAGCT GAAGTCACCA ACAGGCCATC GGCTTGGAGA 
CCACTAGTGC TTCTCATCCC TCTCCGCCTG GGACTGACAG ACATCAATGA GGCCTATGTG 
GAGACGCTGA AGCACTGTTT CATGATGCCC CAGTCCCTGG GTGTTATTGG AGGGAAGCCC 
AACAGTGCCC ACTACTTTAT TGGCTATGTT GGGGAGGAGC TCATCTATCT GGACCCCCAC 
ACTACACAGC CTGCAGTGGA GCTGACTGAC AGCTGCTTCA TCCCCGACGA GAGCTTCCAC 
TGCCAGCACC CTCCCTCTAG GATGGGCATT GGAGAGCTTG ACCCGTCCAT TGCTGTGGGG 
TTTTTCTGTA AGACGGAGGA AGACTTTAAC GACTGGTGTC AGCAAGTCAA AAAGCTATCC 
CAGCTTGGAG GTGCCCTGCC CATGTTTGAG CTGGTGGAAC AGCAGCCTTC CCATCTGGCC 
TGCCAGGATG TCCTGAACCT GTCCCTAGAC TCTTCTGATG TAGAGAGACT GGAGAGGTTT 
TTTGACTCTG AGGATGAAGA CTTTGAAATC TTATCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atg4b ( XM_006529793.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529856.1 Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu28374
Clone ID Related Accession (Same CDS sequence)	XM_006529793.3 , XM_006529793.2
Accession Version	XM_006529793.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	cysteine protease ATG4B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006529793.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCGGT GTGGACAGAT GATCTTTGCC CAGGCCCTGG TATGCCGGCA CTTAGGTCGA 
GATTGGAGGT GGACTCAGCG GAAGAGGCAG CCTGACAGCT ACTTTAATGT CCTCAATGCT 
TTCCTCGACA GGAAGGACAG CTACTATTCC ATCCATCAGA TAGCGCAAAT GGGAGTTGGC 
GAAGGCAAGT CTATAGGCCA GTGGTACGGG CCGAACACTG TTGCCCAGGT CCTCAAGAAA 
CTTGCTGTAT TCGACACATG GAGTTCCTTG GCTGTTCACA TAGCAATGGA CAACACTGTG 
GTGATGGAGG AAATCAGAAG GTTATGCAGG GCCAACCTTC CCTGTGTTGG GGCGGCTGCA 
CTTCCTACTG ATTCAGAGAG GCACTGTAAT GGGTTCCCTG CTGGAGCTGA AGTCACCAAC 
AGGCCATCGG CTTGGAGACC ACTAGTGCTT CTCATCCCTC TCCGCCTGGG ACTGACAGAC 
ATCAATGAGG CCTATGTGGA GACGCTGAAG CACTGTTTCA TGATGCCCCA GTCCCTGGGT 
GTTATTGGAG GGAAGCCCAA CAGTGCCCAC TACTTTATTG GCTATGTTGG GGAGGAGCTC 
ATCTATCTGG ACCCCCACAC TACACAGCCT GCAGTGGAGC TGACTGACAG CTGCTTCATC 
CCCGACGAGA GCTTCCACTG CCAGCACCCT CCCTCTAGGA TGGGCATTGG AGAGCTTGAC 
CCGTCCATTG CTGTGGGGTT TTTCTGTAAG ACGGAGGAAG ACTTTAACGA CTGGTGTCAG 
CAAGTCAAAA AGCTATCCCA GCTTGGAGGT GCCCTGCCCA TGTTTGAGCT GGTGGAACAG 
CAGCCTTCCC ATCTGGCCTG CCAGGATGTC CTGAACCTGT CCCTAGACTC TTCTGATGTA 
GAGAGACTGG AGAGGTTTTT TGACTCTGAG GATGAAGACT TTGAAATCTT ATCCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529856.1
CDS	508..1467
Translation	MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL

Target ORF information:

RefSeq Version	XM_006529793.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529793.2

ORF Insert Sequence:

ATGCTTCGGT GTGGACAGAT GATCTTTGCC CAGGCCCTGG TATGCCGGCA CTTAGGTCGA 
GATTGGAGGT GGACTCAGCG GAAGAGGCAG CCTGACAGCT ACTTTAATGT CCTCAATGCT 
TTCCTCGACA GGAAGGACAG CTACTATTCC ATCCATCAGA TAGCGCAAAT GGGAGTTGGC 
GAAGGCAAGT CTATAGGCCA GTGGTACGGG CCGAACACTG TTGCCCAGGT CCTCAAGAAA 
CTTGCTGTAT TCGACACATG GAGTTCCTTG GCTGTTCACA TAGCAATGGA CAACACTGTG 
GTGATGGAGG AAATCAGAAG GTTATGCAGG GCCAACCTTC CCTGTGTTGG GGCGGCTGCA 
CTTCCTACTG ATTCAGAGAG GCACTGTAAT GGGTTCCCTG CTGGAGCTGA AGTCACCAAC 
AGGCCATCGG CTTGGAGACC ACTAGTGCTT CTCATCCCTC TCCGCCTGGG ACTGACAGAC 
ATCAATGAGG CCTATGTGGA GACGCTGAAG CACTGTTTCA TGATGCCCCA GTCCCTGGGT 
GTTATTGGAG GGAAGCCCAA CAGTGCCCAC TACTTTATTG GCTATGTTGG GGAGGAGCTC 
ATCTATCTGG ACCCCCACAC TACACAGCCT GCAGTGGAGC TGACTGACAG CTGCTTCATC 
CCCGACGAGA GCTTCCACTG CCAGCACCCT CCCTCTAGGA TGGGCATTGG AGAGCTTGAC 
CCGTCCATTG CTGTGGGGTT TTTCTGTAAG ACGGAGGAAG ACTTTAACGA CTGGTGTCAG 
CAAGTCAAAA AGCTATCCCA GCTTGGAGGT GCCCTGCCCA TGTTTGAGCT GGTGGAACAG 
CAGCCTTCCC ATCTGGCCTG CCAGGATGTC CTGAACCTGT CCCTAGACTC TTCTGATGTA 
GAGAGACTGG AGAGGTTTTT TGACTCTGAG GATGAAGACT TTGAAATCTT ATCCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atg4b ( NM_001368266.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001355195.1 Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 2, mRNA.

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CloneID	OMu84633
Clone ID Related Accession (Same CDS sequence)	NM_001368266.1
Accession Version	NM_001368266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Mus musculus(house mouse)
Product	cysteine protease ATG4B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC162891.6 and CJ155817.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGATTGGA GGTGGACTCA GCGGAAGAGG CAGCCTGACA GCTACTTTAA TGTCCTCAAT 
GCTTTCCTCG ACAGGAAGGA CAGCTACTAT TCCATCCATC AGATAGCGCA AATGGGAGTT 
GGCGAAGGCA AGTCTATAGG CCAGTGGTAC GGGCCGAACA CTGTTGCCCA GGTCCTCAAG 
AAACTTGCTG TATTCGACAC ATGGAGTTCC TTGGCTGTTC ACATAGCAAT GGACAACACT 
GTGGTGATGG AGGAAATCAG AAGGTTATGC AGGGCCAACC TTCCCTGTGT TGGGGCGGCT 
GCACTTCCTA CTGATTCAGA GAGGCACTGT AATGGGTTCC CTGCTGGAGC TGAAGTCACC 
AACAGGCCAT CGGCTTGGAG ACCACTAGTG CTTCTCATCC CTCTCCGCCT GGGACTGACA 
GACATCAATG AGGCCTATGT GGAGACGCTG AAGCACTGTT TCATGATGCC CCAGTCCCTG 
GGTGTTATTG GAGGGAAGCC CAACAGTGCC CACTACTTTA TTGGCTATGT TGGGGAGGAG 
CTCATCTATC TGGACCCCCA CACTACACAG CCTGCAGTGG AGCTGACTGA CAGCTGCTTC 
ATCCCCGACG AGAGCTTCCA CTGCCAGCAC CCTCCCTCTA GGATGGGCAT TGGAGAGCTT 
GACCCGTCCA TTGCTGTGGG GTTTTTCTGT AAGACGGAGG AAGACTTTAA CGACTGGTGT 
CAGCAAGTCA AAAAGCTATC CCAGCTTGGA GGTGCCCTGC CCATGTTTGA GCTGGTGGAA 
CAGCAGCCTT CCCATCTGGC CTGCCAGGAT GTCCTGAACC TGTCCCTAGA CTCTTCTGAT 
GTAGAGAGAC TGGAGAGGTT TTTTGACTCT GAGGATGAAG ACTTTGAAAT CTTATCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355195.1
CDS	141..1223
Translation	MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRRNFPAIDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL

Target ORF information:

RefSeq Version	NM_001368266.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368266.1

ORF Insert Sequence:

ATGGACGCAG CCACTTTGAC ATATGATACT CTCCGGTTTG CTGAATTTGA AGATTTCCCT 
GAGACCTCAG AGCCTGTTTG GATTCTGGGC AGAAAATACA GCATTTTCAC AGAGAAGGAC 
GAAATCTTGT CTGATGTTGC ATCCAGACTT TGGTTTACAT ACAGGAGAAA CTTTCCAGCT 
ATTGATTGGA GGTGGACTCA GCGGAAGAGG CAGCCTGACA GCTACTTTAA TGTCCTCAAT 
GCTTTCCTCG ACAGGAAGGA CAGCTACTAT TCCATCCATC AGATAGCGCA AATGGGAGTT 
GGCGAAGGCA AGTCTATAGG CCAGTGGTAC GGGCCGAACA CTGTTGCCCA GGTCCTCAAG 
AAACTTGCTG TATTCGACAC ATGGAGTTCC TTGGCTGTTC ACATAGCAAT GGACAACACT 
GTGGTGATGG AGGAAATCAG AAGGTTATGC AGGGCCAACC TTCCCTGTGT TGGGGCGGCT 
GCACTTCCTA CTGATTCAGA GAGGCACTGT AATGGGTTCC CTGCTGGAGC TGAAGTCACC 
AACAGGCCAT CGGCTTGGAG ACCACTAGTG CTTCTCATCC CTCTCCGCCT GGGACTGACA 
GACATCAATG AGGCCTATGT GGAGACGCTG AAGCACTGTT TCATGATGCC CCAGTCCCTG 
GGTGTTATTG GAGGGAAGCC CAACAGTGCC CACTACTTTA TTGGCTATGT TGGGGAGGAG 
CTCATCTATC TGGACCCCCA CACTACACAG CCTGCAGTGG AGCTGACTGA CAGCTGCTTC 
ATCCCCGACG AGAGCTTCCA CTGCCAGCAC CCTCCCTCTA GGATGGGCAT TGGAGAGCTT 
GACCCGTCCA TTGCTGTGGG GTTTTTCTGT AAGACGGAGG AAGACTTTAA CGACTGGTGT 
CAGCAAGTCA AAAAGCTATC CCAGCTTGGA GGTGCCCTGC CCATGTTTGA GCTGGTGGAA 
CAGCAGCCTT CCCATCTGGC CTGCCAGGAT GTCCTGAACC TGTCCCTAGA CTCTTCTGAT 
GTAGAGAGAC TGGAGAGGTT TTTTGACTCT GAGGATGAAG ACTTTGAAAT CTTATCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atg4b ( XM_006529793.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529856.1 Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.

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CloneID	OMu28374
Clone ID Related Accession (Same CDS sequence)	XM_006529793.3 , XM_006529793.2
Accession Version	XM_006529793.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	cysteine protease ATG4B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529793.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCGGT GTGGACAGAT GATCTTTGCC CAGGCCCTGG TATGCCGGCA CTTAGGTCGA 
GATTGGAGGT GGACTCAGCG GAAGAGGCAG CCTGACAGCT ACTTTAATGT CCTCAATGCT 
TTCCTCGACA GGAAGGACAG CTACTATTCC ATCCATCAGA TAGCGCAAAT GGGAGTTGGC 
GAAGGCAAGT CTATAGGCCA GTGGTACGGG CCGAACACTG TTGCCCAGGT CCTCAAGAAA 
CTTGCTGTAT TCGACACATG GAGTTCCTTG GCTGTTCACA TAGCAATGGA CAACACTGTG 
GTGATGGAGG AAATCAGAAG GTTATGCAGG GCCAACCTTC CCTGTGTTGG GGCGGCTGCA 
CTTCCTACTG ATTCAGAGAG GCACTGTAAT GGGTTCCCTG CTGGAGCTGA AGTCACCAAC 
AGGCCATCGG CTTGGAGACC ACTAGTGCTT CTCATCCCTC TCCGCCTGGG ACTGACAGAC 
ATCAATGAGG CCTATGTGGA GACGCTGAAG CACTGTTTCA TGATGCCCCA GTCCCTGGGT 
GTTATTGGAG GGAAGCCCAA CAGTGCCCAC TACTTTATTG GCTATGTTGG GGAGGAGCTC 
ATCTATCTGG ACCCCCACAC TACACAGCCT GCAGTGGAGC TGACTGACAG CTGCTTCATC 
CCCGACGAGA GCTTCCACTG CCAGCACCCT CCCTCTAGGA TGGGCATTGG AGAGCTTGAC 
CCGTCCATTG CTGTGGGGTT TTTCTGTAAG ACGGAGGAAG ACTTTAACGA CTGGTGTCAG 
CAAGTCAAAA AGCTATCCCA GCTTGGAGGT GCCCTGCCCA TGTTTGAGCT GGTGGAACAG 
CAGCCTTCCC ATCTGGCCTG CCAGGATGTC CTGAACCTGT CCCTAGACTC TTCTGATGTA 
GAGAGACTGG AGAGGTTTTT TGACTCTGAG GATGAAGACT TTGAAATCTT ATCCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529856.1
CDS	520..1479
Translation	MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL

Target ORF information:

RefSeq Version	XM_006529793.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus autophagy related 4B, cysteine peptidase (Atg4b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529793.3

ORF Insert Sequence:

ATGCTTCGGT GTGGACAGAT GATCTTTGCC CAGGCCCTGG TATGCCGGCA CTTAGGTCGA 
GATTGGAGGT GGACTCAGCG GAAGAGGCAG CCTGACAGCT ACTTTAATGT CCTCAATGCT 
TTCCTCGACA GGAAGGACAG CTACTATTCC ATCCATCAGA TAGCGCAAAT GGGAGTTGGC 
GAAGGCAAGT CTATAGGCCA GTGGTACGGG CCGAACACTG TTGCCCAGGT CCTCAAGAAA 
CTTGCTGTAT TCGACACATG GAGTTCCTTG GCTGTTCACA TAGCAATGGA CAACACTGTG 
GTGATGGAGG AAATCAGAAG GTTATGCAGG GCCAACCTTC CCTGTGTTGG GGCGGCTGCA 
CTTCCTACTG ATTCAGAGAG GCACTGTAAT GGGTTCCCTG CTGGAGCTGA AGTCACCAAC 
AGGCCATCGG CTTGGAGACC ACTAGTGCTT CTCATCCCTC TCCGCCTGGG ACTGACAGAC 
ATCAATGAGG CCTATGTGGA GACGCTGAAG CACTGTTTCA TGATGCCCCA GTCCCTGGGT 
GTTATTGGAG GGAAGCCCAA CAGTGCCCAC TACTTTATTG GCTATGTTGG GGAGGAGCTC 
ATCTATCTGG ACCCCCACAC TACACAGCCT GCAGTGGAGC TGACTGACAG CTGCTTCATC 
CCCGACGAGA GCTTCCACTG CCAGCACCCT CCCTCTAGGA TGGGCATTGG AGAGCTTGAC 
CCGTCCATTG CTGTGGGGTT TTTCTGTAAG ACGGAGGAAG ACTTTAACGA CTGGTGTCAG 
CAAGTCAAAA AGCTATCCCA GCTTGGAGGT GCCCTGCCCA TGTTTGAGCT GGTGGAACAG 
CAGCCTTCCC ATCTGGCCTG CCAGGATGTC CTGAACCTGT CCCTAGACTC TTCTGATGTA 
GAGAGACTGG AGAGGTTTTT TGACTCTGAG GATGAAGACT TTGAAATCTT ATCCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.
Autophagy13(8)1331-1347(2017 Aug)
Ramkumar A,Murthy D,Raja DA,Singh A,Krishnan A,Khanna S,Vats A,Thukral L,Sharma P,Sivasubbu S,Rani R,Natarajan VT,Gokhale RS

ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy13(5)834-853(2017 May)
Skytte Rasmussen M,Mouilleron S,Kumar Shrestha B,Wirth M,Lee R,Bowitz Larsen K,Abudu Princely Y,O'Reilly N,Sj?ttem E,Tooze SA,Lamark T,Johansen T

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.
Cell host & microbe19(1)102-13(2016 Jan)
Lu Q,Yokoyama CC,Williams JW,Baldridge MT,Jin X,DesRochers B,Bricker T,Wilen CB,Bagaitkar J,Loginicheva E,Sergushichev A,Kreamalmeyer D,Keller BC,Zhao Y,Kambal A,Green DR,Martinez J,Dinauer MC,Holtzman MJ,Crouch EC,Beatty W,Boon AC,Zhang H,Randolph GJ,Artyomov MN,Virgin HW

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.
Nature528(7583)565-9(2015 Dec)
Kimmey JM,Huynh JP,Weiss LA,Park S,Kambal A,Debnath J,Virgin HW,Stallings CL

MicroRNA-34a Suppresses Autophagy in Tubular Epithelial Cells in Acute Kidney Injury.
American journal of nephrology42(2)168-75(2015)
Liu XJ,Hong Q,Wang Z,Yu YY,Zou X,Xu LH

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Atg4b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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電話

FAX

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