Uqcr11 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uqcr11
Entrez Gene ID	66594
Full Name	ubiquinol-cytochrome c reductase, complex III subunit XI
Synonyms	0710008D09Rik,AL022707,Uqcr
General protein information	Preferred Names ubiquinol-cytochrome c reductase, complex III subunit XI Names cytochrome b-c1 complex subunit 10 complex III subunit 10 complex III subunit XI ubiquinol-cytochrome c reductase (6.4kD) subunit ubiquinol-cytochrome c reductase complex 6.4 kDa protein ubiquinol-cytochrome c reductase subunit
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_025650.2	NP_079926.1	cytochrome b-c1 complex subunit 10

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	UQCR11	XP_001148727.1
Mus musculus (house mouse)	Uqcr11	NP_079926.1
Canis lupus familiaris (dog)	UQCR11	XP_854591.1
Bos taurus (cattle)	UQCR11	NP_776640.1
Rattus norvegicus (Norway rat)	Uqcr11	NP_001119569.1
	UQCR	XP_001096084.1
Homo sapiens (human)	UQCR11	NP_006821.1

Gene Ontology
Bibliography

Related articles in PubMed

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Doucet-Beaupr? H, Gilbert C, Profes MS, Chabrat A, Pacelli C, Gigu?re N, Rioux V, Charest J, Deng Q, Laguna A, Ericson J, Perlmann T, Ang SL, Cicchetti F, Parent M, Trudeau LE, L?vesque M
Proceedings of the National Academy of Sciences of the United States of America113(30)E4387-96(2016 07)

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Dai N, Zhao L, Wrighting D, Kr?mer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
Cell metabolism21(4)609-21(2015 Apr)

Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochrome b expression and a marked reduction in ubiquinol-cytochrome c reductase activity in mouse heart mitochondria.
Xu F, Ackerley C, Maj MC, Addis JB, Levandovskiy V, Lee J, Mackay N, Cameron JM, Robinson BH
The Biochemical journal416(1)15-26(2008 Nov)

Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria.
Schilling B, Murray J, Yoo CB, Row RH, Cusack MP, Capaldi RA, Gibson BW
Biochimica et biophysica acta1762(2)213-22(2006 Feb)

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Uqcr11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uqcr11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18833	NM_025650.2 Latest version!	Mus musculus ubiquinol-cytochrome c reductase, complex III subunit XI (Uqcr11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uqcr11 ( NM_025650.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079926.1 Mus musculus ubiquinol-cytochrome c reductase, complex III subunit XI (Uqcr11), mRNA.

Price & Availability↑

CloneID	OMu18833
Clone ID Related Accession (Same CDS sequence)	NM_025650.2
Accession Version	NM_025650.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 171bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	cytochrome b-c1 complex subunit 10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003033.1 and BU529273.1. On Sep 6, 2006 this sequence version replaced NM_025650.1. ##Evidence-Data-START## Transcript exon combination :: BU529273.1, AK003033.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGCTGAGCA GGTTTCTAGG CCCGCGCTAC CGGGAACTGG CCAGAAACTG GATTCCCACA 
GCCGGCATGT GGGGCACTGT GGGTGCCGTG GGACTGGTGT GGGCCACGGA CTGGCGGCTG 
ATCCTGGACT GGGTGCCTTA CATCAACGGC AAGTTTAAGA AGGACGATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079926.1
CDS	77..247
Translation	MLSRFLGPRYRELARNWIPTAGMWGTVGAVGLVWATDWRLILDWVPYINGKFKKDD

Target ORF information:

RefSeq Version	NM_025650.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquinol-cytochrome c reductase, complex III subunit XI (Uqcr11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025650.2

ORF Insert Sequence:

1
61
121

ATGCTGAGCA GGTTTCTAGG CCCGCGCTAC CGGGAACTGG CCAGAAACTG GATTCCCACA 
GCCGGCATGT GGGGCACTGT GGGTGCCGTG GGACTGGTGT GGGCCACGGA CTGGCGGCTG 
ATCCTGGACT GGGTGCCTTA CATCAACGGC AAGTTTAAGA AGGACGATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America113(30)E4387-96(2016 07)
Doucet-Beaupr? H,Gilbert C,Profes MS,Chabrat A,Pacelli C,Gigu?re N,Rioux V,Charest J,Deng Q,Laguna A,Ericson J,Perlmann T,Ang SL,Cicchetti F,Parent M,Trudeau LE,L?vesque M

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Cell metabolism21(4)609-21(2015 Apr)
Dai N,Zhao L,Wrighting D,Kr?mer D,Majithia A,Wang Y,Cracan V,Borges-Rivera D,Mootha VK,Nahrendorf M,Thorburn DR,Minichiello L,Altshuler D,Avruch J

Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochrome b expression and a marked reduction in ubiquinol-cytochrome c reductase activity in mouse heart mitochondria.
The Biochemical journal416(1)15-26(2008 Nov)
Xu F,Ackerley C,Maj MC,Addis JB,Levandovskiy V,Lee J,Mackay N,Cameron JM,Robinson BH

Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria.
Biochimica et biophysica acta1762(2)213-22(2006 Feb)
Schilling B,Murray J,Yoo CB,Row RH,Cusack MP,Capaldi RA,Gibson BW

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Cell115(5)629-40(2003 Nov)
Mootha VK,Bunkenborg J,Olsen JV,Hjerrild M,Wisniewski JR,Stahl E,Bolouri MS,Ray HN,Sihag S,Kamal M,Patterson N,Lander ES,Mann M