Polr1e cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Polr1e
Entrez Gene ID	64424
Full Name	polymerase (RNA) I polypeptide E
Synonyms	53kDa,AU042259,D030019D19Rik,Paf53,Praf1
General protein information	Preferred Names polymerase (RNA) I polypeptide E Names DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerase I subunit E RNA polymerase I associated factor (Paf53) RNA polymerase I subunit A49 RNA polymerase I-associated factor 53 polymerase (RNA) I associated factor 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001285800.1	NP_001272729.1	DNA-directed RNA polymerase I subunit RPA49 isoform a
NM_022811.3	NP_073722.1	DNA-directed RNA polymerase I subunit RPA49 isoform b

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Polr1e	NP_001101408.1
Xenopus tropicalis (tropical clawed frog)	polr1e	NP_001120306.1
Gallus gallus (chicken)	POLR1E	XP_424416.3
Danio rerio (zebrafish)	polr1e	NP_001018540.1
Mus musculus (house mouse)	Polr1e	NP_073722.1
Homo sapiens (human)	POLR1E	NP_071935.1
Pan troglodytes (chimpanzee)	POLR1E	XP_001169824.1
Canis lupus familiaris (dog)	POLR1E	XP_531998.2
Bos taurus (cattle)	POLR1E	NP_001029580.1

Gene Ontology
Bibliography

Related articles in PubMed

PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression.
Rothblum LI, Rothblum K, Chang E
Gene61255-60(2017 May)

Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.
Penrod Y, Rothblum K, Rothblum LI
Biochemistry51(33)6519-26(2012 Aug)

TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Ou YH, Torres M, Ram R, Formstecher E, Roland C, Cheng T, Brekken R, Wurz R, Tasker A, Polverino T, Tan SL, White MA
Molecular cell41(4)458-70(2011 Feb)

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.
Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M
Molecular and cellular biology24(14)6338-49(2004 Jul)

PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I.
Seither P, Iben S, Thiry M, Grummt I
Biological chemistry382(8)1163-70(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DNA sequencing demonstrated that in the absence of ectopic PAF53 expression, cells demonstrated unique means of surviving; including recombination or the utilization of alternative reading frames. We never observed a clone in which one PAF53 gene is expressed, unless there was also ectopic expression In the absence of ectopic gene expression, the gene products of both endogenous genes were expressed, irrespective of wheth
Title: PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression.

yeast A34.5/A49 and mammalian PAF49/PAF53 heterodimeric complexes interact through species-specific sequence elements that appear to assume similar structural motifs.
Title: Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.

The following Polr1e gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Polr1e cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12626	NM_022811.3 Latest version!	Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$251.30 $359.00
OMu17110	NM_001285800.1 Latest version!	Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Polr1e ( NM_022811.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_073722.1 Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu12626
Clone ID Related Accession (Same CDS sequence)	NM_022811.3
Accession Version	NM_022811.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1305bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL824706.8, AK132556.1 and AK083948.1. On Oct 23, 2013 this sequence version replaced NM_022811.2. Transcript Variant: This variant (2) lacks two alternate exons that result in the loss of an in-frame segment in the central coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: AK132556.1, AK083948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACTC TGGAGTCTCC TGGGATGGAT GACCAGGCTG GAGACACGGA GACAGAGGCG 
CTACAGAGTG CAAGGTGGCT GTACTGTGGA GAGCCCGACG ACAGGCAGAA AGCTGTGCTG 
GTCCAGTTCT CCAATGGGAA GCTGCAGAAT CCGGGCGACA TGCGCTTCAC CTTGTACAAC 
AGCACCGACT TAGTAAACCC CAGGCAGAGG AGTCACCGGA TCGTGGCAGC TGAAACAGAT 
AGGCTCTCCT ATGTCGGAAA CAATTTTGGG ACCGGTGCCC TCAAATGCAA TGCTCTTTGC 
AGACACTTTG TGGGAATTCT GAATAAGACC TCTGGCCAGA TGGAAGTCTA TGATGCCGAA 
CTGTTCAACA TGCAGCCGCT GTTTGCTGAC GATGCTATTG AGCGAGAGCC TCCTCTGGAG 
AATCAGAACA AGACTTTCAG GGACAAGTTG GATTCTTGCA TTGAAGCCTT TGGAAGCACC 
AAGCAGAAGC GGTCCCTAAA CTCCAGGCGG ATGAACAAAG TTGGCAGCGA GTCTCTGAAT 
CTCAGTGTGG CGAAAGCCGC GGAGAGTATT ATTGATACAA AGGGTGTGAA TGCGCTGGTC 
AGCGATGCCA TGCAGGATGA CTTACAAGAT GGCGTCCTCT ACCTTCCTCC CTGCTACGCT 
GACGCAGCCA AGCCGGAAGA CGTGTATAGA TTTGAAGACA TTCTGTCCCC GGCCGAGTAT 
GATGCTCTTG AGAGCCCATC CGAAGCCTTC AGAAAGGTCA CATCGGAAGA CATACTGAAG 
ATGATTGAAG AGAACAGCCA CTGCTCCTAC GTCATAGAAA TGCTGAAGTC TCTGCCCATA 
GATGAGGTCC ACCGGAACCG GCAAGCCCGG AGCATCTGGT TCCTAGACGC CCTCATCAGA 
TTCCGAGCTC AGAAAGTGAT AAAGGGGAAA AGAGCCTTAG GGCCTGGAAT CCCGCACATT 
ATCAACACCA AGCTGCTGAA ACAGTTCACC TGCTTGACCT ACAACAACGG CAGGTTACAG 
AACCTCATTT CAAGTTCTAT GAGGGCCAAG ATCACTTCGT ATGCGATTAT ACTTGCCCTG 
CACATAAATA ACTTCCAGGT TGACCTGACA GCGTTGCAGA AGGACTTGAA GCTGAGTGAG 
AAAAGGATGA TTGAGATAGC GAAAGCCATG AGGCTGAAGA TCTCCAAACA AAAGGTGTCC 
CTGGCAGATG GCAGGGAAGA GAGTCACAGA CTGGGCACTC TGTCTGTCCC ACTGCCTCCA 
GCCCAGAACT CTGATCGACA GTCAAAGCGG AGGAAAATGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073722.1
CDS	64..1368
Translation	MATLESPGMDDQAGDTETEALQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGDMRFTLYNSTDLVNPRQRSHRIVAAETDRLSYVGNNFGTGALKCNALCRHFVGILNKTSGQMEVYDAELFNMQPLFADDAIEREPPLENQNKTFRDKLDSCIEAFGSTKQKRSLNSRRMNKVGSESLNLSVAKAAESIIDTKGVNALVSDAMQDDLQDGVLYLPPCYADAAKPEDVYRFEDILSPAEYDALESPSEAFRKVTSEDILKMIEENSHCSYVIEMLKSLPIDEVHRNRQARSIWFLDALIRFRAQKVIKGKRALGPGIPHIINTKLLKQFTCLTYNNGRLQNLISSSMRAKITSYAIILALHINNFQVDLTALQKDLKLSEKRMIEIAKAMRLKISKQKVSLADGREESHRLGTLSVPLPPAQNSDRQSKRRKMN

Target ORF information:

RefSeq Version	NM_022811.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022811.3

ORF Insert Sequence:

ATGGCTACTC TGGAGTCTCC TGGGATGGAT GACCAGGCTG GAGACACGGA GACAGAGGCG 
CTACAGAGTG CAAGGTGGCT GTACTGTGGA GAGCCCGACG ACAGGCAGAA AGCTGTGCTG 
GTCCAGTTCT CCAATGGGAA GCTGCAGAAT CCGGGCGACA TGCGCTTCAC CTTGTACAAC 
AGCACCGACT TAGTAAACCC CAGGCAGAGG AGTCACCGGA TCGTGGCAGC TGAAACAGAT 
AGGCTCTCCT ATGTCGGAAA CAATTTTGGG ACCGGTGCCC TCAAATGCAA TGCTCTTTGC 
AGACACTTTG TGGGAATTCT GAATAAGACC TCTGGCCAGA TGGAAGTCTA TGATGCCGAA 
CTGTTCAACA TGCAGCCGCT GTTTGCTGAC GATGCTATTG AGCGAGAGCC TCCTCTGGAG 
AATCAGAACA AGACTTTCAG GGACAAGTTG GATTCTTGCA TTGAAGCCTT TGGAAGCACC 
AAGCAGAAGC GGTCCCTAAA CTCCAGGCGG ATGAACAAAG TTGGCAGCGA GTCTCTGAAT 
CTCAGTGTGG CGAAAGCCGC GGAGAGTATT ATTGATACAA AGGGTGTGAA TGCGCTGGTC 
AGCGATGCCA TGCAGGATGA CTTACAAGAT GGCGTCCTCT ACCTTCCTCC CTGCTACGCT 
GACGCAGCCA AGCCGGAAGA CGTGTATAGA TTTGAAGACA TTCTGTCCCC GGCCGAGTAT 
GATGCTCTTG AGAGCCCATC CGAAGCCTTC AGAAAGGTCA CATCGGAAGA CATACTGAAG 
ATGATTGAAG AGAACAGCCA CTGCTCCTAC GTCATAGAAA TGCTGAAGTC TCTGCCCATA 
GATGAGGTCC ACCGGAACCG GCAAGCCCGG AGCATCTGGT TCCTAGACGC CCTCATCAGA 
TTCCGAGCTC AGAAAGTGAT AAAGGGGAAA AGAGCCTTAG GGCCTGGAAT CCCGCACATT 
ATCAACACCA AGCTGCTGAA ACAGTTCACC TGCTTGACCT ACAACAACGG CAGGTTACAG 
AACCTCATTT CAAGTTCTAT GAGGGCCAAG ATCACTTCGT ATGCGATTAT ACTTGCCCTG 
CACATAAATA ACTTCCAGGT TGACCTGACA GCGTTGCAGA AGGACTTGAA GCTGAGTGAG 
AAAAGGATGA TTGAGATAGC GAAAGCCATG AGGCTGAAGA TCTCCAAACA AAAGGTGTCC 
CTGGCAGATG GCAGGGAAGA GAGTCACAGA CTGGGCACTC TGTCTGTCCC ACTGCCTCCA 
GCCCAGAACT CTGATCGACA GTCAAAGCGG AGGAAAATGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Polr1e ( NM_001285800.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272729.1 Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu17110
Clone ID Related Accession (Same CDS sequence)	NM_001285800.1
Accession Version	NM_001285800.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL824706.8, AK132556.1 and AK083948.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC034783.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133, SAMN01164143 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACTC TGGAGTCTCC TGGGATGGAT GACCAGGCTG GAGACACGGA GACAGAGGCG 
CTACAGAGTG CAAGGTGGCT GTACTGTGGA GAGCCCGACG ACAGGCAGAA AGCTGTGCTG 
GTCCAGTTCT CCAATGGGAA GCTGCAGAAT CCGGGCGACA TGCGCTTCAC CTTGTACAAC 
AGCACCGACT TAGTAAACCC CAGGCAGAGG AGTCACCGGA TCGTGGCAGC TGAAACAGAT 
AGGCTCTCCT ATGTCGGAAA CAATTTTGGG ACCGGTGCCC TCAAATGCAA TGCTCTTTGC 
AGACACTTTG TGGGAATTCT GAATAAGACC TCTGGCCAGA TGGAAGTCTA TGATGCCGAA 
CTGTTCAACA TGCAGCCGCT GTTTGCTGGA ATGGGAACTG AAGTCATCAA ACTTGGTGGC 
CAACACCTTT ACCTGCTGGC CTTCTGCCAA CCCTCCAAGA ACCTGGCTGA GGCAGGTGAC 
CTGCTGCTGA GCCGACACCG GCAAGGCCAT TGCATTGCAG TCCTGCTGGA TGACGATGCT 
ATTGAGCGAG AGCCTCCTCT GGAGAATCAG AACAAGACTT TCAGGGACAA GTTGGATTCT 
TGCATTGAAG CCTTTGGAAG CACCAAGCAG AAGCGGTCCC TAAACTCCAG GCGGATGAAC 
AAAGTTGGCA GCGAGTCTCT GAATCTCAGT GTGGCGAAAG CCGCGGAGAG TATTATTGAT 
ACAAAGGGTG TGAATGCGCT GGTCAGCGAT GCCATGCAGG ATGACTTACA AGATGGCGTC 
CTCTACCTTC CTCCCTGCTA CGCTGACGCA GCCAAGCCGG AAGACGTGTA TAGATTTGAA 
GACATTCTGT CCCCGGCCGA GTATGATGCT CTTGAGAGCC CATCCGAAGC CTTCAGAAAG 
GTCACATCGG AAGACATACT GAAGATGATT GAAGAGAACA GCCACTGCTC CTACGTCATA 
GAAATGCTGA AGTCTCTGCC CATAGATGAG GTCCACCGGA ACCGGCAAGC CCGGAGCATC 
TGGTTCCTAG ACGCCCTCAT CAGATTCCGA GCTCAGAAAG TGATAAAGGG GAAAAGAGCC 
TTAGGGCCTG GAATCCCGCA CATTATCAAC ACCAAGCTGC TGAAACAGTT CACCTGCTTG 
ACCTACAACA ACGGCAGGTT ACAGAACCTC ATTTCAAGTT CTATGAGGGC CAAGATCACT 
TCGTATGCGA TTATACTTGC CCTGCACATA AATAACTTCC AGGTTGACCT GACAGCGTTG 
CAGAAGGACT TGAAGCTGAG TGAGAAAAGG ATGATTGAGA TAGCGAAAGC CATGAGGCTG 
AAGATCTCCA AACAAAAGGT GTCCCTGGCA GATGGCAGGG AAGAGAGTCA CAGACTGGGC 
ACTCTGTCTG TCCCACTGCC TCCAGCCCAG AACTCTGATC GACAGTCAAA GCGGAGGAAA 
ATGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272729.1
CDS	64..1512
Translation	MATLESPGMDDQAGDTETEALQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGDMRFTLYNSTDLVNPRQRSHRIVAAETDRLSYVGNNFGTGALKCNALCRHFVGILNKTSGQMEVYDAELFNMQPLFAGMGTEVIKLGGQHLYLLAFCQPSKNLAEAGDLLLSRHRQGHCIAVLLDDDAIEREPPLENQNKTFRDKLDSCIEAFGSTKQKRSLNSRRMNKVGSESLNLSVAKAAESIIDTKGVNALVSDAMQDDLQDGVLYLPPCYADAAKPEDVYRFEDILSPAEYDALESPSEAFRKVTSEDILKMIEENSHCSYVIEMLKSLPIDEVHRNRQARSIWFLDALIRFRAQKVIKGKRALGPGIPHIINTKLLKQFTCLTYNNGRLQNLISSSMRAKITSYAIILALHINNFQVDLTALQKDLKLSEKRMIEIAKAMRLKISKQKVSLADGREESHRLGTLSVPLPPAQNSDRQSKRRKMN

Target ORF information:

RefSeq Version	NM_001285800.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus polymerase (RNA) I polypeptide E (Polr1e), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285800.1

ORF Insert Sequence:

ATGGCTACTC TGGAGTCTCC TGGGATGGAT GACCAGGCTG GAGACACGGA GACAGAGGCG 
CTACAGAGTG CAAGGTGGCT GTACTGTGGA GAGCCCGACG ACAGGCAGAA AGCTGTGCTG 
GTCCAGTTCT CCAATGGGAA GCTGCAGAAT CCGGGCGACA TGCGCTTCAC CTTGTACAAC 
AGCACCGACT TAGTAAACCC CAGGCAGAGG AGTCACCGGA TCGTGGCAGC TGAAACAGAT 
AGGCTCTCCT ATGTCGGAAA CAATTTTGGG ACCGGTGCCC TCAAATGCAA TGCTCTTTGC 
AGACACTTTG TGGGAATTCT GAATAAGACC TCTGGCCAGA TGGAAGTCTA TGATGCCGAA 
CTGTTCAACA TGCAGCCGCT GTTTGCTGGA ATGGGAACTG AAGTCATCAA ACTTGGTGGC 
CAACACCTTT ACCTGCTGGC CTTCTGCCAA CCCTCCAAGA ACCTGGCTGA GGCAGGTGAC 
CTGCTGCTGA GCCGACACCG GCAAGGCCAT TGCATTGCAG TCCTGCTGGA TGACGATGCT 
ATTGAGCGAG AGCCTCCTCT GGAGAATCAG AACAAGACTT TCAGGGACAA GTTGGATTCT 
TGCATTGAAG CCTTTGGAAG CACCAAGCAG AAGCGGTCCC TAAACTCCAG GCGGATGAAC 
AAAGTTGGCA GCGAGTCTCT GAATCTCAGT GTGGCGAAAG CCGCGGAGAG TATTATTGAT 
ACAAAGGGTG TGAATGCGCT GGTCAGCGAT GCCATGCAGG ATGACTTACA AGATGGCGTC 
CTCTACCTTC CTCCCTGCTA CGCTGACGCA GCCAAGCCGG AAGACGTGTA TAGATTTGAA 
GACATTCTGT CCCCGGCCGA GTATGATGCT CTTGAGAGCC CATCCGAAGC CTTCAGAAAG 
GTCACATCGG AAGACATACT GAAGATGATT GAAGAGAACA GCCACTGCTC CTACGTCATA 
GAAATGCTGA AGTCTCTGCC CATAGATGAG GTCCACCGGA ACCGGCAAGC CCGGAGCATC 
TGGTTCCTAG ACGCCCTCAT CAGATTCCGA GCTCAGAAAG TGATAAAGGG GAAAAGAGCC 
TTAGGGCCTG GAATCCCGCA CATTATCAAC ACCAAGCTGC TGAAACAGTT CACCTGCTTG 
ACCTACAACA ACGGCAGGTT ACAGAACCTC ATTTCAAGTT CTATGAGGGC CAAGATCACT 
TCGTATGCGA TTATACTTGC CCTGCACATA AATAACTTCC AGGTTGACCT GACAGCGTTG 
CAGAAGGACT TGAAGCTGAG TGAGAAAAGG ATGATTGAGA TAGCGAAAGC CATGAGGCTG 
AAGATCTCCA AACAAAAGGT GTCCCTGGCA GATGGCAGGG AAGAGAGTCA CAGACTGGGC 
ACTCTGTCTG TCCCACTGCC TCCAGCCCAG AACTCTGATC GACAGTCAAA GCGGAGGAAA 
ATGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression.
Gene61255-60(2017 May)
Rothblum LI,Rothblum K,Chang E

Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.
Biochemistry51(33)6519-26(2012 Aug)
Penrod Y,Rothblum K,Rothblum LI

TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Molecular cell41(4)458-70(2011 Feb)
Ou YH,Torres M,Ram R,Formstecher E,Roland C,Cheng T,Brekken R,Wurz R,Tasker A,Polverino T,Tan SL,White MA

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.
Molecular and cellular biology24(14)6338-49(2004 Jul)
Yamamoto K,Yamamoto M,Hanada K,Nogi Y,Matsuyama T,Muramatsu M

PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I.
Biological chemistry382(8)1163-70(2001 Aug)
Seither P,Iben S,Thiry M,Grummt I