Akr1c12 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Akr1c12
Entrez Gene ID	622402
Full Name	aldo-keto reductase family 1, member C12
Synonyms	AI266976,Akra
General protein information	Preferred Names aldo-keto reductase family 1, member C12 Names aldo-keto reductase family 1, member C12 aldo-keto reductase a
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_013777.2	NP_038805.2	aldo-keto reductase family 1, member C12

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Akr1c13	NP_038806.2
Mus musculus (house mouse)	Akr1c12	NP_038805.2
Rattus norvegicus (Norway rat)	Akr1c12l1	NP_001129216.1
Rattus norvegicus (Norway rat)	Akr1c12	NP_001163813.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH
PloS one6(2)e17286(2011 Feb)

Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD
Genome biology9(6)R99(2008)

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.
Vergnes L, Phan J, Stolz A, Reue K
Journal of lipid research44(3)503-11(2003 Mar)

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.
Du Y, Tsai S, Keller JR, Williams SC
The Journal of biological chemistry275(10)6724-32(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Akr1c12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akr1c12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09949	NM_013777.2 Latest version!	Mus musculus aldo-keto reductase family 1, member C12 (Akr1c12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Akr1c12 ( NM_013777.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038805.2 Mus musculus aldo-keto reductase family 1, member C12 (Akr1c12), mRNA.

Price & Availability↑

CloneID	OMu09949
Clone ID Related Accession (Same CDS sequence)	NM_013777.2
Accession Version	NM_013777.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	aldo-keto reductase family 1, member C12
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY148924.1, AK007716.1 and BY583815.1. On Jan 26, 2006 this sequence version replaced NM_013777.1. ##Evidence-Data-START## Transcript exon combination :: AK007716.1, BC063780.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTCCA AACAGCACTA TGTCAAACTA AACGATGGCC ACTTAATTCC TGCCCTGGGC 
TTTGGCACCT ATAAACCCAA GGAGGTTCCC AAGAGTAAGT CACTGGAGGC TGCATGCCTA 
GCTCTAGATG TTGGGTACCG CCATGTTGAT ACTGCTTATG CATACCAAGT AGAAGAGGAG 
ATAGGACAGG CCATTCAAAG CAAGATTAAA GCTGGGGTTG TAAAGAGAGA AGACCTGTTC 
ATCACTACAA AGCTTTGGTG CGGTTGCTTT CGACCAGAGC TGGTCAAGCC TGCTTTGGAA 
AAATCACTGA AAAGCCTTCA GCTGGATTAT GTTGATCTTT ACCTTATACA TTACCCAGTG 
CCAATGAAGC CAGGGGATAA TGAATCTCCA TTAGATGAGA ACGGGAAATT TCTATTGGAC 
ACTGTGGATT TCTGTGACAC ATGGGAGAGG TTGGAGGAGT GTAAGGATGC AGGATTGGTC 
AAGTCCATTG GGGTGTCCAA CTTTAACCAC AGGCAGCTAG AGAGAATCCT CAACAAGCCA 
GGACTGAAGT ACAAACCTGT CTGCAACCAG GTTGAATGTC ATCTCTATTT GAACCAGAGT 
AAGCTATTGG ATTACTGCAA GTCAAAAGAC ATTGTTCTCG TTGCTTACGG TGCTCTGGGG 
ACCCAGCGAT ATAAAGAATG GGTGGACCAG AACTCCCCAG TTCTCTTGAA CGATCCAGTT 
CTTTGTGATG TGGCCAAAAG GAACAAGCGA AGCCCTGCCC TAATTGCACT TCGATACCTG 
TTTCAACGTG GGATTGTGCC CCTGGCCCAG AGTTTCAAAG AGAATGAGAT GAGAGAGAAT 
TTGCAGGTTT TTGAATTTCA GTTGTCCCCT GAGGACATGA AAACACTAGA TGGCCTGAAC 
AAAAACTTTC GATACCTTCC AGCAGAGTTC CTTGCTGACC ACCCAGAGTA TCCATTTTCA 
GAGGAATATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038805.2
CDS	44..1015
Translation	MSSKQHYVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDLFITTKLWCGCFRPELVKPALEKSLKSLQLDYVDLYLIHYPVPMKPGDNESPLDENGKFLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQSKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKRNKRSPALIALRYLFQRGIVPLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLPAEFLADHPEYPFSEEY

Target ORF information:

RefSeq Version	NM_013777.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus aldo-keto reductase family 1, member C12 (Akr1c12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013777.2

ORF Insert Sequence:

ATGAGCTCCA AACAGCACTA TGTCAAACTA AACGATGGCC ACTTAATTCC TGCCCTGGGC 
TTTGGCACCT ATAAACCCAA GGAGGTTCCC AAGAGTAAGT CACTGGAGGC TGCATGCCTA 
GCTCTAGATG TTGGGTACCG CCATGTTGAT ACTGCTTATG CATACCAAGT AGAAGAGGAG 
ATAGGACAGG CCATTCAAAG CAAGATTAAA GCTGGGGTTG TAAAGAGAGA AGACCTGTTC 
ATCACTACAA AGCTTTGGTG CGGTTGCTTT CGACCAGAGC TGGTCAAGCC TGCTTTGGAA 
AAATCACTGA AAAGCCTTCA GCTGGATTAT GTTGATCTTT ACCTTATACA TTACCCAGTG 
CCAATGAAGC CAGGGGATAA TGAATCTCCA TTAGATGAGA ACGGGAAATT TCTATTGGAC 
ACTGTGGATT TCTGTGACAC ATGGGAGAGG TTGGAGGAGT GTAAGGATGC AGGATTGGTC 
AAGTCCATTG GGGTGTCCAA CTTTAACCAC AGGCAGCTAG AGAGAATCCT CAACAAGCCA 
GGACTGAAGT ACAAACCTGT CTGCAACCAG GTTGAATGTC ATCTCTATTT GAACCAGAGT 
AAGCTATTGG ATTACTGCAA GTCAAAAGAC ATTGTTCTCG TTGCTTACGG TGCTCTGGGG 
ACCCAGCGAT ATAAAGAATG GGTGGACCAG AACTCCCCAG TTCTCTTGAA CGATCCAGTT 
CTTTGTGATG TGGCCAAAAG GAACAAGCGA AGCCCTGCCC TAATTGCACT TCGATACCTG 
TTTCAACGTG GGATTGTGCC CCTGGCCCAG AGTTTCAAAG AGAATGAGAT GAGAGAGAAT 
TTGCAGGTTT TTGAATTTCA GTTGTCCCCT GAGGACATGA AAACACTAGA TGGCCTGAAC 
AAAAACTTTC GATACCTTCC AGCAGAGTTC CTTGCTGACC ACCCAGAGTA TCCATTTTCA 
GAGGAATATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
PloS one6(2)e17286(2011 Feb)
Thiagarajan RD,Georgas KM,Rumballe BA,Lesieur E,Chiu HS,Taylor D,Tang DT,Grimmond SM,Little MH

Identification of transcripts with enriched expression in the developing and adult pancreas.
Genome biology9(6)R99(2008)
Hoffman BG,Zavaglia B,Witzsche J,Ruiz de Algara T,Beach M,Hoodless PA,Jones SJ,Marra MA,Helgason CD

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.
Journal of lipid research44(3)503-11(2003 Mar)
Vergnes L,Phan J,Stolz A,Reue K

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.
The Journal of biological chemistry275(10)6724-32(2000 Mar)
Du Y,Tsai S,Keller JR,Williams SC