Eid1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eid1
Entrez Gene ID	58521
Full Name	EP300 interacting inhibitor of differentiation 1
Synonyms	2610002K20Rik,Cri1,EID-1,ORF12,PNAS-22,PTD014
General protein information	Preferred Names EP300 interacting inhibitor of differentiation 1 Names EP300-interacting inhibitor of differentiation 1 CREBBP/EP300 inhibitory protein 1 E1A-like inhibitor of differentiation 1 eid1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_025613.3	NP_079889.2	EP300-interacting inhibitor of differentiation 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC100299757	XP_005205613.1
	EID1	XP_001113389.1
Bos taurus (cattle)	EID1	NP_001091847.1
Mus musculus (house mouse)	Eid1	NP_079889.2
Rattus norvegicus (Norway rat)	Eid1	NP_001102675.1
Canis lupus familiaris (dog)	EID1	XP_850599.1
Homo sapiens (human)	EID1	NP_055150.1
Pan troglodytes (chimpanzee)	EID1	NP_001233427.1

Gene Ontology
Bibliography

Related articles in PubMed

Protein Palmitoylation Regulates Neural Stem Cell Differentiation by Modulation of EID1 Activity.
Chen X, Du Z, Li X, Wang L, Wang F, Shi W, Hao A
Molecular neurobiology53(8)5722-36(2016 Oct)

Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.
Ye B, Dai Z, Liu B, Wang R, Li C, Huang G, Wang S, Xia P, Yang X, Kuwahara K, Sakaguchi N, Fan Z
Stem cells (Dayton, Ohio)32(3)623-35(2014 Mar)

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Wajapeyee N, Malonia SK, Palakurthy RK, Green MR
Genes & development27(20)2221-6(2013 Oct)

The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains.
Teatero SA, Thomassin JL, Zhu L, Diez E, Malo D, Gruenheid S
Gut microbes2(3)173-7(2011 May-Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pcid2 is present in the CBP/p300-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation.
Title: Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.

Cri1 does not control C. rodentium colonic hyperplasia
Title: Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice.

This study supports Cri1 as the major locus controlling susceptibility following murine infection with C. rodentium, and suggests a cause of mortality common to the susceptible C3, C3Ou and FVB strains of mice.
Title: The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains.

EID-1 is expressed in the mouse testis, and its expression decreases during testis development. The results of the present study suggest that EID-1 can act as a repressor, regulating the function of SF-1.
Title: EID-1 interacts with orphan nuclear receptor SF-1 and represses its transactivation.

isolation of mouse E1A-like inhibitor of differentiation 1 (EID1) as a candidate coinhibitor for SHP
Title: A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.

The following Eid1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eid1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58395	NM_025613.3 Latest version!	Mus musculus EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eid1 ( NM_025613.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079889.2 Mus musculus EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA.

Price & Availability↑

CloneID	OMu58395
Clone ID Related Accession (Same CDS sequence)	NM_025613.3
Accession Version	NM_025613.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Mus musculus(house mouse)
Product	EP300-interacting inhibitor of differentiation 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY703074.1, AK011293.1, AL357453.1, DV050753.1, AA016688.1, BU610167.1 and BU700648.1. On Jun 2, 2007 this sequence version replaced NM_025613.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGCGGAGA TGGCAGAGCT TTGCGAGCTG TACGAAGAAA GCAACGAGTT GCAGATGGAC 
GTGCTGCCCG GCGAGGGCTA TATGGAGGTA GGCCGCGGGG CCCGCGGGCC GGCCCCGGAG 
GAGGGCCCCA TGGAGGAGGA GGCCGGGCCG GCCGCCGCCC GCGCCCAGCG CGGTCTGTTC 
CCCGAGGCTG GCGCGGACCT GGAAGGCGAC GAGTTTGATG ACTGGGAGGA CGACTACGAG 
TTCCCTGAAG AGGAGCGCTG GAGCGGCGCG ATGCACAGGG TGTCCGCCGC CCTGGAGGAA 
GCCAACAAGG TGTTCCTGCG AACCGCGCGA GCCGGAGATG CCCTGGATGG CGGCTTTCAG 
GCGCGGTGTG AGAAGAGCCC TTTCGACCAG CTAGCTTTTA TCGAAGAGCT GTTTTCGCTG 
ATGGTTGTCA ATCGACTGAC CGAAGAGCTC GGTTGTGATG AGATCATTGA TCGAGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079889.2
CDS	93..572
Translation	MAEMAELCELYEESNELQMDVLPGEGYMEVGRGARGPAPEEGPMEEEAGPAAARAQRGLFPEAGADLEGDEFDDWEDDYEFPEEERWSGAMHRVSAALEEANKVFLRTARAGDALDGGFQARCEKSPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE

Target ORF information:

RefSeq Version	NM_025613.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025613.3

ORF Insert Sequence:

ATGGCGGAGA TGGCAGAGCT TTGCGAGCTG TACGAAGAAA GCAACGAGTT GCAGATGGAC 
GTGCTGCCCG GCGAGGGCTA TATGGAGGTA GGCCGCGGGG CCCGCGGGCC GGCCCCGGAG 
GAGGGCCCCA TGGAGGAGGA GGCCGGGCCG GCCGCCGCCC GCGCCCAGCG CGGTCTGTTC 
CCCGAGGCTG GCGCGGACCT GGAAGGCGAC GAGTTTGATG ACTGGGAGGA CGACTACGAG 
TTCCCTGAAG AGGAGCGCTG GAGCGGCGCG ATGCACAGGG TGTCCGCCGC CCTGGAGGAA 
GCCAACAAGG TGTTCCTGCG AACCGCGCGA GCCGGAGATG CCCTGGATGG CGGCTTTCAG 
GCGCGGTGTG AGAAGAGCCC TTTCGACCAG CTAGCTTTTA TCGAAGAGCT GTTTTCGCTG 
ATGGTTGTCA ATCGACTGAC CGAAGAGCTC GGTTGTGATG AGATCATTGA TCGAGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protein Palmitoylation Regulates Neural Stem Cell Differentiation by Modulation of EID1 Activity.
Molecular neurobiology53(8)5722-36(2016 Oct)
Chen X,Du Z,Li X,Wang L,Wang F,Shi W,Hao A

Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.
Stem cells (Dayton, Ohio)32(3)623-35(2014 Mar)
Ye B,Dai Z,Liu B,Wang R,Li C,Huang G,Wang S,Xia P,Yang X,Kuwahara K,Sakaguchi N,Fan Z

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Genes & development27(20)2221-6(2013 Oct)
Wajapeyee N,Malonia SK,Palakurthy RK,Green MR

The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains.
Gut microbes2(3)173-7(2011 May-Jun)
Teatero SA,Thomassin JL,Zhu L,Diez E,Malo D,Gruenheid S