Klrc3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klrc3
Entrez Gene ID	58179
Full Name	killer cell lectin-like receptor subfamily C, member 3
Synonyms	Klrc2,Nkg2e
General protein information	Preferred Names killer cell lectin-like receptor subfamily C, member 3 Names killer cell lectin-like receptor subfamily C, member 3 killer cell lectin-like receptor subfamily C, member 2 natural killer cell group 2E cell receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 F3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006506430.2	XP_006506493.1	killer cell lectin-like receptor subfamily C, member 3 isoform X1
NM_021378.1	NP_067353.1	killer cell lectin-like receptor subfamily C, member 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Klrc3	NP_067353.1
Mus musculus (house mouse)	Klrc2	NP_034783.3
Rattus norvegicus (Norway rat)	Klrc3	NP_001025079.1

Gene Ontology
Bibliography

Related articles in PubMed

Development and function of CD94-deficient natural killer cells.
Orr MT, Wu J, Fang M, Sigal LJ, Spee P, Egebjerg T, Dissen E, Fossum S, Phillips JH, Lanier LL
PloS one5(12)e15184(2010 Dec)

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I.
Koike J, Wakao H, Ishizuka Y, Sato TA, Hamaoki M, Seino K, Koseki H, Nakayama T, Taniguchi M
The Journal of experimental medicine199(1)137-44(2004 Jan)

Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells.
Vance RE, Jamieson AM, Raulet DH
The Journal of experimental medicine190(12)1801-12(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

expression of CD94 and its associated NKG2A, NKG2C, and NKG2E subunits is dispensable for NK cell development, education, and many NK cell functions
Title: Development and function of CD94-deficient natural killer cells.

The following Klrc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klrc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12265	NM_021378.1 Latest version!	Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu37475	XM_006506430.2 Latest version!	Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klrc3 ( NM_021378.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067353.1 Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), mRNA.

Price & Availability↑

CloneID	OMu12265
Clone ID Related Accession (Same CDS sequence)	NM_021378.1
Accession Version	NM_021378.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	killer cell lectin-like receptor subfamily C, member 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF195779.1. ##Evidence-Data-START## Transcript exon combination :: AF195779.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGAGTCACC TGCTTGGAAC TGAACAGGCC TCAGAACCCA GGAAAGCCAC AAAGAAAACC 
CAGGCGCAGC TCCGTTTCAG TAATGCAGCA GGAGATCGCC TGCTGGAGTT TAGCCTTCAA 
CATGCTTCCC AGAAGCATCT GAAGGCCAGC AGGCATGGCT ACTGCAAAAA TTTTGCATCA 
CCTCCAGAGA AGCTCATCGC TGGAATCCTG GGCACCATCT GGTTTACCTT ATTGATTGCT 
CTAGTAATCT CAACCAGAAT TGTTTCTCCA TATATAAACC ACAGTCTATC TTCAGCACAA 
ACTTATGCTC TTTGTCCAAA GGAATGGATC TTATATTCTC ACAATTGTTA TTACATTGGC 
ATGGAAAGAA AATCTTGGAA TGACAGTTTG GTGTCCTGCA TTTCCAAAAA CTGTAGTCTG 
CTTTATATAG ACAGTGAAGA GGAGCAGGAC TTTCTGCAAT CCCTTTCACT GGTCTCATGG 
ACTGGAATCC TTCGGAAGGG CAGAGGTCAG CCCTGGGTCT GGAAAAAAGA CTCAACTTTC 
AAACCAAAGA TAGCAGAGAT TCTCCATGAT GAATGTAACT GTGCCATGAT GTCAGCTTCT 
GGTCTCACAG CAGACAGCTG TACAACTTTA CATCCATATC TTTGTAAGTG TAAATTCCCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067353.1
CDS	1..666
Translation	MSHLLGTEQASEPRKATKKTQAQLRFSNAAGDRLLEFSLQHASQKHLKASRHGYCKNFASPPEKLIAGILGTIWFTLLIALVISTRIVSPYINHSLSSAQTYALCPKEWILYSHNCYYIGMERKSWNDSLVSCISKNCSLLYIDSEEEQDFLQSLSLVSWTGILRKGRGQPWVWKKDSTFKPKIAEILHDECNCAMMSASGLTADSCTTLHPYLCKCKFPI

Target ORF information:

RefSeq Version	NM_021378.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021378.1

ORF Insert Sequence:

ATGAGTCACC TGCTTGGAAC TGAACAGGCC TCAGAACCCA GGAAAGCCAC AAAGAAAACC 
CAGGCGCAGC TCCGTTTCAG TAATGCAGCA GGAGATCGCC TGCTGGAGTT TAGCCTTCAA 
CATGCTTCCC AGAAGCATCT GAAGGCCAGC AGGCATGGCT ACTGCAAAAA TTTTGCATCA 
CCTCCAGAGA AGCTCATCGC TGGAATCCTG GGCACCATCT GGTTTACCTT ATTGATTGCT 
CTAGTAATCT CAACCAGAAT TGTTTCTCCA TATATAAACC ACAGTCTATC TTCAGCACAA 
ACTTATGCTC TTTGTCCAAA GGAATGGATC TTATATTCTC ACAATTGTTA TTACATTGGC 
ATGGAAAGAA AATCTTGGAA TGACAGTTTG GTGTCCTGCA TTTCCAAAAA CTGTAGTCTG 
CTTTATATAG ACAGTGAAGA GGAGCAGGAC TTTCTGCAAT CCCTTTCACT GGTCTCATGG 
ACTGGAATCC TTCGGAAGGG CAGAGGTCAG CCCTGGGTCT GGAAAAAAGA CTCAACTTTC 
AAACCAAAGA TAGCAGAGAT TCTCCATGAT GAATGTAACT GTGCCATGAT GTCAGCTTCT 
GGTCTCACAG CAGACAGCTG TACAACTTTA CATCCATATC TTTGTAAGTG TAAATTCCCC 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Klrc3 ( XM_006506430.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506493.1 Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37475
Clone ID Related Accession (Same CDS sequence)	XM_006506430.2
Accession Version	XM_006506430.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	killer cell lectin-like receptor subfamily C, member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006506430.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTCACC TGCTTGGAAC TGAACAGGCC TCAGAACCCA GGAAAGCCAC AAAGAAAACC 
CAGGCGCAGC TCCGTTTCAG TAATGCAGCA GGAGATCGCC TGCTGGAGTT TAGCCTTCAA 
CATGCTTCCC AGAAGCATCT GAAGGCCAGC AGGCATGGCT ACTGCAAAAA TTTTGCATCA 
CCTCCAGAGA AGCTCATCGC TGGAATCCTG GGCACCATCT GGTTTACCTT ATTGATTGCT 
CTAGTAATCT CAACCAGAAT TGTTTCTCCA TATGCTGAAC TGAAGAAGCA GATCCACCCC 
TTCTTGGTTA GAACCCAGAA AGGCTCACAC GTCTTGCTCT CCAAAGATAT AAACCACAGT 
CTATCTTCAG CACAAACTTA TGCTCTTTGT CCAAAGGAAT GGATCTTATA TTCTCACAAT 
TGTTATTACA TTGGCATGGA AAGAAAATCT TGGAATGACA GTTTGGTGTC CTGCATTTCC 
AAAAACTGTA GTCTGCTTTA TATAGACAGT GAAGAGGAGC AGGACTTTCT GCAATCCCTT 
TCACTGGTCT CATGGACTGG AATCCTTCGG AAGGGCAGAG GTCAGCCCTG GGTCTGGAAA 
AAAGACTCAA CTTTCAAACC AAAGATAGCA GAGATTCTCC ATGATGAATG TAACTGTGCC 
ATGATGTCAG CTTCTGGTCT CACAGCAGAC AGCTGTACAA CTTTACATCC ATATCTTTGT 
AAGTGTAAAT TCCCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506493.1
CDS	224..964
Translation	MSHLLGTEQASEPRKATKKTQAQLRFSNAAGDRLLEFSLQHASQKHLKASRHGYCKNFASPPEKLIAGILGTIWFTLLIALVISTRIVSPYAELKKQIHPFLVRTQKGSHVLLSKDINHSLSSAQTYALCPKEWILYSHNCYYIGMERKSWNDSLVSCISKNCSLLYIDSEEEQDFLQSLSLVSWTGILRKGRGQPWVWKKDSTFKPKIAEILHDECNCAMMSASGLTADSCTTLHPYLCKCKFPI

Target ORF information:

RefSeq Version	XM_006506430.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus killer cell lectin-like receptor subfamily C, member 3 (Klrc3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506430.2

ORF Insert Sequence:

ATGAGTCACC TGCTTGGAAC TGAACAGGCC TCAGAACCCA GGAAAGCCAC AAAGAAAACC 
CAGGCGCAGC TCCGTTTCAG TAATGCAGCA GGAGATCGCC TGCTGGAGTT TAGCCTTCAA 
CATGCTTCCC AGAAGCATCT GAAGGCCAGC AGGCATGGCT ACTGCAAAAA TTTTGCATCA 
CCTCCAGAGA AGCTCATCGC TGGAATCCTG GGCACCATCT GGTTTACCTT ATTGATTGCT 
CTAGTAATCT CAACCAGAAT TGTTTCTCCA TATGCTGAAC TGAAGAAGCA GATCCACCCC 
TTCTTGGTTA GAACCCAGAA AGGCTCACAC GTCTTGCTCT CCAAAGATAT AAACCACAGT 
CTATCTTCAG CACAAACTTA TGCTCTTTGT CCAAAGGAAT GGATCTTATA TTCTCACAAT 
TGTTATTACA TTGGCATGGA AAGAAAATCT TGGAATGACA GTTTGGTGTC CTGCATTTCC 
AAAAACTGTA GTCTGCTTTA TATAGACAGT GAAGAGGAGC AGGACTTTCT GCAATCCCTT 
TCACTGGTCT CATGGACTGG AATCCTTCGG AAGGGCAGAG GTCAGCCCTG GGTCTGGAAA 
AAAGACTCAA CTTTCAAACC AAAGATAGCA GAGATTCTCC ATGATGAATG TAACTGTGCC 
ATGATGTCAG CTTCTGGTCT CACAGCAGAC AGCTGTACAA CTTTACATCC ATATCTTTGT 
AAGTGTAAAT TCCCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Development and function of CD94-deficient natural killer cells.
PloS one5(12)e15184(2010 Dec)
Orr MT,Wu J,Fang M,Sigal LJ,Spee P,Egebjerg T,Dissen E,Fossum S,Phillips JH,Lanier LL

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I.
The Journal of experimental medicine199(1)137-44(2004 Jan)
Koike J,Wakao H,Ishizuka Y,Sato TA,Hamaoki M,Seino K,Koseki H,Nakayama T,Taniguchi M

Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells.
The Journal of experimental medicine190(12)1801-12(1999 Dec)
Vance RE,Jamieson AM,Raulet DH