Sfrp5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sfrp5
Entrez Gene ID	54612
Full Name	secreted frizzled-related sequence protein 5
Synonyms	AI605071,SARP3
General protein information	Preferred Names secreted frizzled-related sequence protein 5 Names secreted frizzled-related protein 5 sFRP-5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_018780.3	NP_061250.2	secreted frizzled-related protein 5 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sfrp5	NP_061250.2
Gallus gallus (chicken)	SFRP5	XP_421707.1
Danio rerio (zebrafish)	sfrp5	NP_571933.1
Homo sapiens (human)	SFRP5	NP_003006.2
Canis lupus familiaris (dog)	SFRP5	XP_543955.3
Xenopus tropicalis (tropical clawed frog)	sfrp5	NP_001004846.1
	LOC707738	XP_001096160.2
Rattus norvegicus (Norway rat)	Sfrp5	NP_001101061.1
Bos taurus (cattle)	SFRP5	NP_776886.1

Gene Ontology
Bibliography

Related articles in PubMed

Plasticity within the niche ensures the maintenance of a
Sanz-Navarro M, Seidel K, Sun Z, Bertonnier-Brouty L, Amendt BA, Klein OD, Michon F
Development (Cambridge, England)145(1)(2018 Jan)

SFRP5 is a target gene transcriptionally regulated by PPAR? in 3T3-L1 adipocytes.
Zeng J, Hu J, Lian Y, Jiang Y, Chen B
Gene641190-195(2018 Jan)

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.
Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H
Developmental cell40(5)439-452.e4(2017 03)

Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle.
Fujii M, Sakaguchi A, Kamata R, Nagao M, Kikuchi Y, Evans SM, Yoshizumi M, Shimono A, Saga Y, Kokubo H
Nature communications814664(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SFRP5 be a target gene of PPARgamma.
Title: SFRP5 is a target gene transcriptionally regulated by PPAR? in 3T3-L1 adipocytes.

the expression of Mest and Sfrp5 were tightly associated across the 5 mouse strains with the highest and lowest expression occurring in DBA/2J and C57BL/6J (B6) respectively suggesting a common mechanism for their regulation.
Title: Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet.

The balance of factors controlling fat deposition can be evaluated in part by the differential expression profiles of Mest and Sfrp5 genes with functions linked to fat deposition as long as there is an active accumulation of fat mass.
Title: Mest and Sfrp5 are biomarkers for healthy adipose tissue.

MicroRNA-124 regulates cell specification in the cochlea through modulation of Sfrp4 and Sfrp5.
Title: MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5.

although high sFRP5 expression inhibits B-lymphopoiesis in vivo, physiologically, it contributes to the preservation of very primitive lymphopoietic progenitors, including hematopoietic stem cells, under high estrogen levels
Title: Estrogen-inducible sFRP5 inhibits early B-lymphopoiesis in vivo, but not during pregnancy.

The following Sfrp5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sfrp5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu13481	NM_018780.3 Latest version!	Mus musculus secreted frizzled-related sequence protein 5 (Sfrp5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$216.30 $309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sfrp5 ( NM_018780.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_061250.2 Mus musculus secreted frizzled-related sequence protein 5 (Sfrp5), mRNA.

Price & Availability↑

CloneID	OMu13481
Clone ID Related Accession (Same CDS sequence)	NM_018780.3
Accession Version	NM_018780.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	secreted frizzled-related protein 5 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL603804.18. On Oct 31, 2009 this sequence version replaced NM_018780.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032921.1, CK626659.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTGGGTGG CCTGGAGCGC ACGGACGGCC GCACTGGCGT TGCTGCTCGG GGCGCTGCAT 
GGGGCGCCAA CACGCGGCCA GGAGTACGAC TACTACGGTT GGCAGGCCGA GCCGCTGCAC 
GGCCGCTCCT ACTCCAAGCC ACCGCAGTGC CTCGACATCC CCGCCGATCT GCCGCTCTGT 
CACACGGTGG GCTACAAGCG CATGCGGCTG CCCAACCTGC TGGAGCACGA GAGCCTGGCC 
GAGGTGAAGC AGCAGGCAAG CAGCTGGCTG CCACTGCTGG CCAAGCGCTG CCACTCAGAC 
ACCCAGGTCT TCCTCTGCTC GCTCTTCGCT CCCGTCTGCC TGGACCGACC CATCTACCCC 
TGCCGCTCGC TGTGCGAAGC CGTGCGCGCC GGCTGCGCTC CGCTCATGGA GGCCTACGGT 
TTCCCTTGGC CCGAGATGCT GCACTGCCAC AAGTTCCCCC TGGACAACGA CCTCTGCATC 
GCGGTGCAGT TCGGGCACCT GCCTGCCACC GCGCCTCCAG TGACCAAGAT CTGTGCCCAG 
TGTGAGATGG AGCACAGCGC TGATGGCCTC ATGGAACAGA TGTGCTCCAG TGACTTTGTG 
GTCAAGATGC GCATTAAGGA GATCAAGATA GACAACGGGG ACCGAAAGTT GATTGGAGCC 
CAGAAGAAGA AGAAGCTGCT CAAGGCAGGC CCCTTAAAGC GCAAGGACAC CAAGAAGCTG 
GTCCTGCATA TGAAGAACGG GGCAAGCTGC CCTTGCCCAC AGTTAGACAA CCTGACGGGC 
AGCTTCCTGG TCATGGGCCG CAAAGTAGAG GGACAGCTGC TGCTCACGGC CGTCTACCGC 
TGGGACAAGA AGAATAAGGA GATGAAGTTT GCAGTCAAAT TCATGTTCTC CTATCCCTGT 
TCCCTCTACT ACCCTTTTTT CTATGGGGCA GCTGAACCCC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061250.2
CDS	242..1186
Translation	MWVAWSARTAALALLLGALHGAPTRGQEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH

Target ORF information:

RefSeq Version	NM_018780.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus secreted frizzled-related sequence protein 5 (Sfrp5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018780.3

ORF Insert Sequence:

ATGTGGGTGG CCTGGAGCGC ACGGACGGCC GCACTGGCGT TGCTGCTCGG GGCGCTGCAT 
GGGGCGCCAA CACGCGGCCA GGAGTACGAC TACTACGGTT GGCAGGCCGA GCCGCTGCAC 
GGCCGCTCCT ACTCCAAGCC ACCGCAGTGC CTCGACATCC CCGCCGATCT GCCGCTCTGT 
CACACGGTGG GCTACAAGCG CATGCGGCTG CCCAACCTGC TGGAGCACGA GAGCCTGGCC 
GAGGTGAAGC AGCAGGCAAG CAGCTGGCTG CCACTGCTGG CCAAGCGCTG CCACTCAGAC 
ACCCAGGTCT TCCTCTGCTC GCTCTTCGCT CCCGTCTGCC TGGACCGACC CATCTACCCC 
TGCCGCTCGC TGTGCGAAGC CGTGCGCGCC GGCTGCGCTC CGCTCATGGA GGCCTACGGT 
TTCCCTTGGC CCGAGATGCT GCACTGCCAC AAGTTCCCCC TGGACAACGA CCTCTGCATC 
GCGGTGCAGT TCGGGCACCT GCCTGCCACC GCGCCTCCAG TGACCAAGAT CTGTGCCCAG 
TGTGAGATGG AGCACAGCGC TGATGGCCTC ATGGAACAGA TGTGCTCCAG TGACTTTGTG 
GTCAAGATGC GCATTAAGGA GATCAAGATA GACAACGGGG ACCGAAAGTT GATTGGAGCC 
CAGAAGAAGA AGAAGCTGCT CAAGGCAGGC CCCTTAAAGC GCAAGGACAC CAAGAAGCTG 
GTCCTGCATA TGAAGAACGG GGCAAGCTGC CCTTGCCCAC AGTTAGACAA CCTGACGGGC 
AGCTTCCTGG TCATGGGCCG CAAAGTAGAG GGACAGCTGC TGCTCACGGC CGTCTACCGC 
TGGGACAAGA AGAATAAGGA GATGAAGTTT GCAGTCAAAT TCATGTTCTC CTATCCCTGT 
TCCCTCTACT ACCCTTTTTT CTATGGGGCA GCTGAACCCC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Plasticity within the niche ensures the maintenance of a
Development (Cambridge, England)145(1)(2018 Jan)
Sanz-Navarro M,Seidel K,Sun Z,Bertonnier-Brouty L,Amendt BA,Klein OD,Michon F

SFRP5 is a target gene transcriptionally regulated by PPAR? in 3T3-L1 adipocytes.
Gene641190-195(2018 Jan)
Zeng J,Hu J,Lian Y,Jiang Y,Chen B

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.
Developmental cell40(5)439-452.e4(2017 03)
Minegishi K,Hashimoto M,Ajima R,Takaoka K,Shinohara K,Ikawa Y,Nishimura H,McMahon AP,Willert K,Okada Y,Sasaki H,Shi D,Fujimori T,Ohtsuka T,Igarashi Y,Yamaguchi TP,Shimono A,Shiratori H,Hamada H

Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle.
Nature communications814664(2017 Mar)
Fujii M,Sakaguchi A,Kamata R,Nagao M,Kikuchi Y,Evans SM,Yoshizumi M,Shimono A,Saga Y,Kokubo H

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Sfrp5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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FAX

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