Exosc9 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exosc9
Entrez Gene ID	50911
Full Name	exosome component 9
Synonyms	PM/Scl-75,Pmscl1,RRP45,p5,p6
General protein information	Preferred Names exosome component 9 Names exosome complex component RRP45 P75 polymyositis-scleroderma overlap syndrome-associated autoantigen autoantigen PM/Scl 1 exosome complex exonuclease RRP45 polymyositis/scleroderma autoantigen 1 polymyositis/scleroderma autoantigen 75 kDa
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_019393.2	NP_062266.1	exosome complex component RRP45

Pathways from BioSystems

Homologies

	EXOSC9	XP_001101063.2
Gallus gallus (chicken)	EXOSC9	NP_001030000.1
Danio rerio (zebrafish)	exosc9	NP_001006077.1
Caenorhabditis elegans (roundworm)	exos-9	NP_741217.1
Saccharomyces cerevisiae (baker's yeast)	RRP45	NP_010566.1
Arabidopsis thaliana (thale cress)	CER7	NP_191609.1
Homo sapiens (human)	EXOSC9	NP_001029366.1
Bos taurus (cattle)	EXOSC9	NP_001030225.1
Mus musculus (house mouse)	Exosc9	NP_062266.1
Magnaporthe oryzae (rice blast fungus)	MGG_08860	XP_003713883.1
Xenopus tropicalis (tropical clawed frog)	exosc9	NP_001120226.1
Canis lupus familiaris (dog)	EXOSC9	XP_533302.2
Rattus norvegicus (Norway rat)	Exosc9	NP_001020577.1
Kluyveromyces lactis	KLLA0C11099g	XP_452695.1
Neurospora crassa	NCU00334	XP_957805.1
Pan troglodytes (chimpanzee)	EXOSC9	XP_001154031.1
Oryza sativa (rice)	Os02g0550700	NP_001047096.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002348	XP_312616.5
Eremothecium gossypii	AGOS_AAL124W	NP_982418.1
Schizosaccharomyces pombe (fission yeast)	SPCC757.08	NP_587683.1
Arabidopsis thaliana (thale cress)	RRP45a	NP_001030684.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome.
Hao L, Vassena R, Wu G, Han Z, Cheng Y, Latham KE, Sapienza C
Biology of reproduction80(5)944-53(2009 May)

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H
BMC genomics9511(2008 Oct)

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Bliskovsky V, Ramsay ES, Scott J, DuBois W, Shi W, Zhang S, Qian X, Lowy DR, Mock BA
Proceedings of the National Academy of Sciences of the United States of America100(25)14982-7(2003 Dec)

Structure and localization of mouse Pmscl1 and Pmscl2 genes.
Bliskovski V, Liddell R, Ramsay ES, Miller MJ, Mock BA
Genomics64(1)106-10(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Exosc9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exosc9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10693	NM_019393.2 Latest version!	Mus musculus exosome component 9 (Exosc9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exosc9 ( NM_019393.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062266.1 Mus musculus exosome component 9 (Exosc9), mRNA.

Price & Availability↑

CloneID	OMu10693
Clone ID Related Accession (Same CDS sequence)	NM_019393.2
Accession Version	NM_019393.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	exosome complex component RRP45
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY078098.1, AK011636.1 and BE634487.1. On Mar 24, 2007 this sequence version replaced NM_019393.1. ##Evidence-Data-START## Transcript exon combination :: BC005622.1, AK010253.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGAGA CGCCGCTTTC CAACTGTGAG CGCCGCTTCC TGCTCCGCGC AATTGAGGAG 
AAGAAGCGCC TGGACGGCAG ACAGACCTAT GATTACAGGA ACATCAGGAT CTCATTCGGA 
ACGGATTATG GATGCTGTAT TGTGGAACTG GGAAAAACAA GAGTCCTTGG ACAGGTTTCC 
TGTGAACTTG TTTCTCCGAA ACTCAATAGG GCAACGGAAG GTATCCTCTT TTTTAACCTT 
GAGCTTTCTC AGATGGCTGC TCCAGCTTTT GAGCCTGGCA GGCAGTCAGA TCTCTTGGTG 
AAGCTGAATC GACTCTTAGA AAGGTGTCTA CGAAATTCAA AGTGTATAGA CACTGAATCT 
CTCTGTGTTG TCGCTGGTGA AAAGGTTTGG CAGATCCGTG TAGACCTACA TTTATTAAAT 
CATGATGGGA ATATTATTGA TGCTGCTAGC ATTGCTGCAA TTGTAGCCTT GTGTCACTTC 
CGAAGACCTG ATGTCTCTGT CCAAGGAGAG GAAGTAACAC TGTATACCCC TGAAGAGCGT 
GATCCCGTGC CATTGAGCAT CCACCATATG CCCATTTGTG TCAGTTTTGC TTTCTTTCAG 
CAAGGAACAT ACTTATTGGT GGACCCCAAT GAACGTGAAG AACGAGTAAT GGATGGCTTG 
CTGGTGATTG CCATGAATAA GCATCGAGAA ATTTGTACTA TTCAGTCTAG TGGTGGGATA 
ATGCTGCTTA AAGACCAGGT TTTCAGATGC AGTAAAATAG CTGGTGTGAA AGTAGCAGAA 
ATCACAGAGC TAATACAGAA AGCTTTGGAA AATGACCAGA GAGTCAGGAA AGAAGGTGGA 
AAATTTGGCT TTGCAGAGTC TATAGCAAAC CAAAGAATCA CAGCGTTTAA AATGGAGACG 
GCCCCTATTG ATACCTCCAA CATAGAGGAG AGAGCAGAAG AAATTATTGC TGAAGCTGAA 
CCTCCCCCAG AAGTTGTTTC TCAACCTGTG CTGTGGACTC CTGGAACTGC CCAGATTGGA 
GACGGAATAG AAAACTCCTG GGGTGACCTT GAAGATTCTG AGAAGGAAGA GGAAGAGGAG 
GAAGGTGGCA TTGATGAAGC TGTCATTCTT GATGATACAA AGATGGACAC TGGAGAAGTT 
TCTGATATTG GGAGTCAAGG TGCCCCTATA GTGCTATCAG ATAGTGAAGA AGAAGAAATG 
ATTATTTTGG AGCCAGAGAA GAACCCAAAG AAAATAAGAG CTCAGACCAG TGCAAACCAG 
AAGGCACCAA GTAAAGGCCA AGGGAAAAGG AAGAAGAAGA AGAGAACTGC TAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062266.1
CDS	81..1397
Translation	MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMETAPIDTSNIEERAEEIIAEAEPPPEVVSQPVLWTPGTAQIGDGIENSWGDLEDSEKEEEEEEGGIDEAVILDDTKMDTGEVSDIGSQGAPIVLSDSEEEEMIILEPEKNPKKIRAQTSANQKAPSKGQGKRKKKKRTAN

Target ORF information:

RefSeq Version	NM_019393.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus exosome component 9 (Exosc9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019393.2

ORF Insert Sequence:

ATGAAGGAGA CGCCGCTTTC CAACTGTGAG CGCCGCTTCC TGCTCCGCGC AATTGAGGAG 
AAGAAGCGCC TGGACGGCAG ACAGACCTAT GATTACAGGA ACATCAGGAT CTCATTCGGA 
ACGGATTATG GATGCTGTAT TGTGGAACTG GGAAAAACAA GAGTCCTTGG ACAGGTTTCC 
TGTGAACTTG TTTCTCCGAA ACTCAATAGG GCAACGGAAG GTATCCTCTT TTTTAACCTT 
GAGCTTTCTC AGATGGCTGC TCCAGCTTTT GAGCCTGGCA GGCAGTCAGA TCTCTTGGTG 
AAGCTGAATC GACTCTTAGA AAGGTGTCTA CGAAATTCAA AGTGTATAGA CACTGAATCT 
CTCTGTGTTG TCGCTGGTGA AAAGGTTTGG CAGATCCGTG TAGACCTACA TTTATTAAAT 
CATGATGGGA ATATTATTGA TGCTGCTAGC ATTGCTGCAA TTGTAGCCTT GTGTCACTTC 
CGAAGACCTG ATGTCTCTGT CCAAGGAGAG GAAGTAACAC TGTATACCCC TGAAGAGCGT 
GATCCCGTGC CATTGAGCAT CCACCATATG CCCATTTGTG TCAGTTTTGC TTTCTTTCAG 
CAAGGAACAT ACTTATTGGT GGACCCCAAT GAACGTGAAG AACGAGTAAT GGATGGCTTG 
CTGGTGATTG CCATGAATAA GCATCGAGAA ATTTGTACTA TTCAGTCTAG TGGTGGGATA 
ATGCTGCTTA AAGACCAGGT TTTCAGATGC AGTAAAATAG CTGGTGTGAA AGTAGCAGAA 
ATCACAGAGC TAATACAGAA AGCTTTGGAA AATGACCAGA GAGTCAGGAA AGAAGGTGGA 
AAATTTGGCT TTGCAGAGTC TATAGCAAAC CAAAGAATCA CAGCGTTTAA AATGGAGACG 
GCCCCTATTG ATACCTCCAA CATAGAGGAG AGAGCAGAAG AAATTATTGC TGAAGCTGAA 
CCTCCCCCAG AAGTTGTTTC TCAACCTGTG CTGTGGACTC CTGGAACTGC CCAGATTGGA 
GACGGAATAG AAAACTCCTG GGGTGACCTT GAAGATTCTG AGAAGGAAGA GGAAGAGGAG 
GAAGGTGGCA TTGATGAAGC TGTCATTCTT GATGATACAA AGATGGACAC TGGAGAAGTT 
TCTGATATTG GGAGTCAAGG TGCCCCTATA GTGCTATCAG ATAGTGAAGA AGAAGAAATG 
ATTATTTTGG AGCCAGAGAA GAACCCAAAG AAAATAAGAG CTCAGACCAG TGCAAACCAG 
AAGGCACCAA GTAAAGGCCA AGGGAAAAGG AAGAAGAAGA AGAGAACTGC TAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome.
Biology of reproduction80(5)944-53(2009 May)
Hao L,Vassena R,Wu G,Han Z,Cheng Y,Latham KE,Sapienza C

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
BMC genomics9511(2008 Oct)
Tamplin OJ,Kinzel D,Cox BJ,Bell CE,Rossant J,Lickert H

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Proceedings of the National Academy of Sciences of the United States of America100(25)14982-7(2003 Dec)
Bliskovsky V,Ramsay ES,Scott J,DuBois W,Shi W,Zhang S,Qian X,Lowy DR,Mock BA

Structure and localization of mouse Pmscl1 and Pmscl2 genes.
Genomics64(1)106-10(2000 Feb)
Bliskovski V,Liddell R,Ramsay ES,Miller MJ,Mock BA