Ldoc1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ldoc1
Entrez Gene ID	434784
Full Name	regulator of NFKB signaling
Synonyms	Gm366,Mar7,Mart7,Rtl7,Sirh7
General protein information	Preferred Names regulator of NFKB signaling Names protein LDOC1 breast cancer, up-regulated 1 leucine zipper, down-regulated in cancer 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A6

mRNA and Protein(s)

mRNA	Protein	Name
NM_001018087.1	NP_001018097.1	protein LDOC1
NM_001018087.2	NP_001018097.1	protein LDOC1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC100855971	XP_003640282.1
Bos taurus (cattle)	LDOC1	NP_001075013.1
Homo sapiens (human)	LDOC1	NP_036449.1
Pan troglodytes (chimpanzee)	LOC100614906	XP_003317782.1
	LDOC1	XP_001085397.1
Mus musculus (house mouse)	Ldoc1	NP_001018097.1
Rattus norvegicus (Norway rat)	Ldoc1	XP_006257679.1

Gene Ontology
Bibliography

Related articles in PubMed

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Walentin K, Hinze C, Werth M, Haase N, Varma S, Morell R, Aue A, P?tschke E, Warburton D, Qiu A, Barasch J, Purf?rst B, Dieterich C, Popova E, Bader M, Dechend R, Staff AC, Yurtdas ZY, Kilic E, Schmidt-Ott KM
Development (Cambridge, England)142(6)1125-36(2015 Mar)

Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition.
Naruse M, Ono R, Irie M, Nakamura K, Furuse T, Hino T, Oda K, Kashimura M, Yamada I, Wakana S, Yokoyama M, Ishino F, Kaneko-Ishino T
Development (Cambridge, England)141(24)4763-71(2014 Dec)

Matrix metalloproteinase-8 regulates transforming growth factor-?1 levels in mouse tongue wounds and fibroblasts in vitro.
Astr?m P, Piril? E, Lithovius R, Heikkola H, Korpi JT, Hern?ndez M, Sorsa T, Salo T
Experimental cell research328(1)217-27(2014 Oct)

A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.
Brandt J, Veith AM, Volff JN
Cytogenetic and genome research110(1-4)307-17(2005)

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.
Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, Volff JN
Gene345(1)101-11(2005 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ldoc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ldoc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu58118	NM_001018087.2 Latest version!	Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu58118	NM_001018087.1	Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ldoc1 ( NM_001018087.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001018097.1 Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.

Price & Availability↑

CloneID	OMu58118
Clone ID Related Accession (Same CDS sequence)	NM_001018087.1 , NM_001018087.2
Accession Version	NM_001018087.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-28
Organism	Mus musculus(house mouse)
Product	protein LDOC1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC052689.1. On Jul 14, 2005 this sequence version replaced XM_486688.2. ##Evidence-Data-START## Transcript is intronless :: BC052689.1 [ECO:0000345] ##Evidence-Data-END##

ATGGTGGAAG AGCTGCTGTC GCTTCTGCAC GCGCTTCTGG ATAGGCACCA AGCCCTGTGC 
ATGGAGAACC ACCAGCTCCT GAAGCAGCTG CGACTGTTGG TGTGTGAGCG GGCCAGGCTG 
CTGCGCCAGG TATGTCCACC GAGCTGTCCG GTGCCCTACC CCTCACGGTT TAGCGGCGAG 
AGTGGTCGGC TCCCTGAGTT TATCATGCAG ACCATGTCTT ACATGCTTGC GAATGAGGAG 
CACTTCTGCA ATGATGCCAT GAAAGTGGCA TTCTTGATCA GCCTCCTCTC CGGGGAAGCT 
GAGGAGTGGG TGATGCCTTA CATCGAGTCA AATAGCTACG TCCTCGGTGA TTATCAGGCC 
TTTGTTGATG AGATGAAGCA GTATTTTGGC TGGGGTACCG ACGACGAAGA TGATGGTGAT 
GATGATGAAG AGGAAGAAAT GGAGGAAGAT CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018097.1
CDS	105..560
Translation	MVEELLSLLHALLDRHQALCMENHQLLKQLRLLVCERARLLRQVCPPSCPVPYPSRFSGESGRLPEFIMQTMSYMLANEEHFCNDAMKVAFLISLLSGEAEEWVMPYIESNSYVLGDYQAFVDEMKQYFGWGTDDEDDGDDDEEEEMEEDH

Target ORF information:

RefSeq Version	NM_001018087.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018087.1

ORF Insert Sequence:

ATGGTGGAAG AGCTGCTGTC GCTTCTGCAC GCGCTTCTGG ATAGGCACCA AGCCCTGTGC 
ATGGAGAACC ACCAGCTCCT GAAGCAGCTG CGACTGTTGG TGTGTGAGCG GGCCAGGCTG 
CTGCGCCAGG TATGTCCACC GAGCTGTCCG GTGCCCTACC CCTCACGGTT TAGCGGCGAG 
AGTGGTCGGC TCCCTGAGTT TATCATGCAG ACCATGTCTT ACATGCTTGC GAATGAGGAG 
CACTTCTGCA ATGATGCCAT GAAAGTGGCA TTCTTGATCA GCCTCCTCTC CGGGGAAGCT 
GAGGAGTGGG TGATGCCTTA CATCGAGTCA AATAGCTACG TCCTCGGTGA TTATCAGGCC 
TTTGTTGATG AGATGAAGCA GTATTTTGGC TGGGGTACCG ACGACGAAGA TGATGGTGAT 
GATGATGAAG AGGAAGAAAT GGAGGAAGAT CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ldoc1 ( NM_001018087.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001018097.1 Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.

Price & Availability↑

CloneID	OMu58118
Clone ID Related Accession (Same CDS sequence)	NM_001018087.1 , NM_001018087.2
Accession Version	NM_001018087.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	protein LDOC1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672025.8 and BC052689.1. On Aug 14, 2018 this sequence version replaced NM_001018087.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: BC052689.1, SRR5189670.43559.1 [ECO:0000345] ##Evidence-Data-END##

ATGGTGGAAG AGCTGCTGTC GCTTCTGCAC GCGCTTCTGG ATAGGCACCA AGCCCTGTGC 
ATGGAGAACC ACCAGCTCCT GAAGCAGCTG CGACTGTTGG TGTGTGAGCG GGCCAGGCTG 
CTGCGCCAGG TATGTCCACC GAGCTGTCCG GTGCCCTACC CCTCACGGTT TAGCGGCGAG 
AGTGGTCGGC TCCCTGAGTT TATCATGCAG ACCATGTCTT ACATGCTTGC GAATGAGGAG 
CACTTCTGCA ATGATGCCAT GAAAGTGGCA TTCTTGATCA GCCTCCTCTC CGGGGAAGCT 
GAGGAGTGGG TGATGCCTTA CATCGAGTCA AATAGCTACG TCCTCGGTGA TTATCAGGCC 
TTTGTTGATG AGATGAAGCA GTATTTTGGC TGGGGTACCG ACGACGAAGA TGATGGTGAT 
GATGATGAAG AGGAAGAAAT GGAGGAAGAT CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018097.1
CDS	100..555
Translation	MVEELLSLLHALLDRHQALCMENHQLLKQLRLLVCERARLLRQVCPPSCPVPYPSRFSGESGRLPEFIMQTMSYMLANEEHFCNDAMKVAFLISLLSGEAEEWVMPYIESNSYVLGDYQAFVDEMKQYFGWGTDDEDDGDDDEEEEMEEDH

Target ORF information:

RefSeq Version	NM_001018087.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus regulator of NFKB signaling (Ldoc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018087.2

ORF Insert Sequence:

ATGGTGGAAG AGCTGCTGTC GCTTCTGCAC GCGCTTCTGG ATAGGCACCA AGCCCTGTGC 
ATGGAGAACC ACCAGCTCCT GAAGCAGCTG CGACTGTTGG TGTGTGAGCG GGCCAGGCTG 
CTGCGCCAGG TATGTCCACC GAGCTGTCCG GTGCCCTACC CCTCACGGTT TAGCGGCGAG 
AGTGGTCGGC TCCCTGAGTT TATCATGCAG ACCATGTCTT ACATGCTTGC GAATGAGGAG 
CACTTCTGCA ATGATGCCAT GAAAGTGGCA TTCTTGATCA GCCTCCTCTC CGGGGAAGCT 
GAGGAGTGGG TGATGCCTTA CATCGAGTCA AATAGCTACG TCCTCGGTGA TTATCAGGCC 
TTTGTTGATG AGATGAAGCA GTATTTTGGC TGGGGTACCG ACGACGAAGA TGATGGTGAT 
GATGATGAAG AGGAAGAAAT GGAGGAAGAT CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Development (Cambridge, England)142(6)1125-36(2015 Mar)
Walentin K,Hinze C,Werth M,Haase N,Varma S,Morell R,Aue A,P?tschke E,Warburton D,Qiu A,Barasch J,Purf?rst B,Dieterich C,Popova E,Bader M,Dechend R,Staff AC,Yurtdas ZY,Kilic E,Schmidt-Ott KM

Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition.
Development (Cambridge, England)141(24)4763-71(2014 Dec)
Naruse M,Ono R,Irie M,Nakamura K,Furuse T,Hino T,Oda K,Kashimura M,Yamada I,Wakana S,Yokoyama M,Ishino F,Kaneko-Ishino T

Matrix metalloproteinase-8 regulates transforming growth factor-?1 levels in mouse tongue wounds and fibroblasts in vitro.
Experimental cell research328(1)217-27(2014 Oct)
Astr?m P,Piril? E,Lithovius R,Heikkola H,Korpi JT,Hern?ndez M,Sorsa T,Salo T

A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.
Cytogenetic and genome research110(1-4)307-17(2005)
Brandt J,Veith AM,Volff JN

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.
Gene345(1)101-11(2005 Jan)
Brandt J,Schrauth S,Veith AM,Froschauer A,Haneke T,Schultheis C,Gessler M,Leimeister C,Volff JN