Grxcr2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grxcr2
Entrez Gene ID	332309
Full Name	glutaredoxin, cysteine rich 2
Synonyms	Gm851
General protein information	Preferred Names glutaredoxin, cysteine rich 2 Names glutaredoxin domain-containing cysteine-rich protein 2 GRXCR1-like protein glutaredoxin domain-containing cysteine-rich protein 1-like protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033426.3	NP_001028598.1	glutaredoxin domain-containing cysteine-rich protein 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GRXCR2	XP_001142483.1
	GRXCR2	XP_001094836.1
Danio rerio (zebrafish)	LOC100535155	XP_003200947.1
Homo sapiens (human)	GRXCR2	NP_001073985.1
Mus musculus (house mouse)	Grxcr2	NP_001028598.1
Canis lupus familiaris (dog)	GRXCR2	XP_003433827.1
Rattus norvegicus (Norway rat)	Grxcr2	NP_001178007.1
Xenopus tropicalis (tropical clawed frog)	grxcr2	XP_002935322.1
Bos taurus (cattle)	GRXCR2	NP_001192387.1
Gallus gallus (chicken)	GRXCR2	XP_004945097.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Expression by Mouse Inner Ear Hair Cells during Development.
Scheffer DI, Shen J, Corey DP, Chen ZY
The Journal of neuroscience : the official journal of the Society for Neuroscience35(16)6366-80(2015 Apr)

A frameshift mutation in GRXCR2 causes recessively inherited hearing loss.
Imtiaz A, Kohrman DC, Naz S
Human mutation35(5)618-24(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grxcr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grxcr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu83520	NM_001033426.3 Latest version!	Mus musculus glutaredoxin, cysteine rich 2 (Grxcr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grxcr2 ( NM_001033426.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028598.1 Mus musculus glutaredoxin, cysteine rich 2 (Grxcr2), mRNA.

Price & Availability↑

CloneID	OMu83520
Clone ID Related Accession (Same CDS sequence)	NM_001033426.3
Accession Version	NM_001033426.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	glutaredoxin domain-containing cysteine-rich protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158418.1, AC132427.4 and AK158432.1. On Nov 19, 2015 this sequence version replaced NM_001033426.2. ##Evidence-Data-START## Transcript exon combination :: AK158432.1, AK158418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGACT CCGAGAAGAA ACTGAATCAG AAGAGCGACG ACAAACCCAG AAAAGTCCGG 
TTTAAAATCT CCTCTTCCTA CAGTGGCCGA GTGTTGAAGC AGGTTTTTGA GGATGGGCAA 
GAATTAGAGT CGCCCAAAGA AGAATATCCT CACAGTTTTC TCCAGGAGGC CCTTGAACCA 
ATGGATGGCG TTTATGGGTC TGGGGAAGTC CCCAAGCCCC AGCCGTACTC CCCCAAGCTG 
ACTGCTCAGA GAATCAGCGT ATTCAGAGAC AGCGGCGCCT ACACTCTGGC GGGCAGCCAG 
CCTCTGTTCA ATGACTACAA GGCGAATGAC CATAAGCCTC CACCCATTAT AGACTTTGGG 
AAGATAATTA TCTATACCAA CAACCTGAAA ATCATCCGAA CCCCGATGGA CAAAAGGGAC 
TTCATGAGGA AAATCCTCCA AAAGGAAGAT GTGGCTGAGG AAGCGTCCCT GATGATCACA 
GGGGAGAATG ATGGAGACAG GGAGCAAGGC TGCCCCCTGC CGGAGCGGAA CGGCAGCCCC 
CTGCCGGAGT CGGAGCGCAC ATTTCTTCAT AGTCAGCACA CACAGGATGG GTTGGTCCCT 
GAGGACTGCC TCCACTGCCA GGGGTCTGGC ATTGCCACCT GTTCTCTGTG CCACGGCAGC 
AAGTTCTCCA TGCTGGCTAA CAGATTCAAG GAGTCCTACC GAGCCCTCAG GTGCCCTGCC 
TGCAACGAGA ATGGCCTGCA ACCTTGCCGA ATTTGCAGCC CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028598.1
CDS	48..812
Translation	MEDSEKKLNQKSDDKPRKVRFKISSSYSGRVLKQVFEDGQELESPKEEYPHSFLQEALEPMDGVYGSGEVPKPQPYSPKLTAQRISVFRDSGAYTLAGSQPLFNDYKANDHKPPPIIDFGKIIIYTNNLKIIRTPMDKRDFMRKILQKEDVAEEASLMITGENDGDREQGCPLPERNGSPLPESERTFLHSQHTQDGLVPEDCLHCQGSGIATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCRICSP

Target ORF information:

RefSeq Version	NM_001033426.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus glutaredoxin, cysteine rich 2 (Grxcr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033426.3

ORF Insert Sequence:

ATGGAGGACT CCGAGAAGAA ACTGAATCAG AAGAGCGACG ACAAACCCAG AAAAGTCCGG 
TTTAAAATCT CCTCTTCCTA CAGTGGCCGA GTGTTGAAGC AGGTTTTTGA GGATGGGCAA 
GAATTAGAGT CGCCCAAAGA AGAATATCCT CACAGTTTTC TCCAGGAGGC CCTTGAACCA 
ATGGATGGCG TTTATGGGTC TGGGGAAGTC CCCAAGCCCC AGCCGTACTC CCCCAAGCTG 
ACTGCTCAGA GAATCAGCGT ATTCAGAGAC AGCGGCGCCT ACACTCTGGC GGGCAGCCAG 
CCTCTGTTCA ATGACTACAA GGCGAATGAC CATAAGCCTC CACCCATTAT AGACTTTGGG 
AAGATAATTA TCTATACCAA CAACCTGAAA ATCATCCGAA CCCCGATGGA CAAAAGGGAC 
TTCATGAGGA AAATCCTCCA AAAGGAAGAT GTGGCTGAGG AAGCGTCCCT GATGATCACA 
GGGGAGAATG ATGGAGACAG GGAGCAAGGC TGCCCCCTGC CGGAGCGGAA CGGCAGCCCC 
CTGCCGGAGT CGGAGCGCAC ATTTCTTCAT AGTCAGCACA CACAGGATGG GTTGGTCCCT 
GAGGACTGCC TCCACTGCCA GGGGTCTGGC ATTGCCACCT GTTCTCTGTG CCACGGCAGC 
AAGTTCTCCA TGCTGGCTAA CAGATTCAAG GAGTCCTACC GAGCCCTCAG GTGCCCTGCC 
TGCAACGAGA ATGGCCTGCA ACCTTGCCGA ATTTGCAGCC CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Expression by Mouse Inner Ear Hair Cells during Development.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(16)6366-80(2015 Apr)
Scheffer DI,Shen J,Corey DP,Chen ZY

A frameshift mutation in GRXCR2 causes recessively inherited hearing loss.
Human mutation35(5)618-24(2014 May)
Imtiaz A,Kohrman DC,Naz S