Arl4c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl4c
Entrez Gene ID	320982
Full Name	ADP-ribosylation factor-like 4C
Synonyms	A630084M22Rik,Arl7,LAK
General protein information	Preferred Names ADP-ribosylation factor-like 4C Names ADP-ribosylation factor-like protein 4C ADP-ribosylation factor-like 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_177305.4	NP_796279.2	ADP-ribosylation factor-like protein 4C

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ARL4C	NP_001095818.1
Mus musculus (house mouse)	Arl4c	NP_796279.2
Danio rerio (zebrafish)	arl4ca	NP_001017749.1
Pan troglodytes (chimpanzee)	ARL4C	XP_001151934.1
Danio rerio (zebrafish)	arl4cb	NP_998413.1
	ARL4C	XP_001115089.1
Canis lupus familiaris (dog)	ARL4C	XP_005635939.1
Homo sapiens (human)	ARL4C	NP_001269360.1
Gallus gallus (chicken)	ARL4C	XP_001237035.2
Xenopus tropicalis (tropical clawed frog)	arl4c	NP_001016707.1

Gene Ontology
Bibliography

Related articles in PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)

A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures.
Matsumoto S, Fujii S, Sato A, Ibuka S, Kagawa Y, Ishii M, Kikuchi A
The EMBO journal33(7)702-18(2014 Apr)

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.
Sun D, Zhang J, Xie J, Wei W, Chen M, Zhao X
FEBS letters586(10)1472-9(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

describe that miR-26, an LXR-suppressed miRNA, inhibits the expression of the ATP-binding cassette transporter A1 (ABCA1) and ADP-ribosylation factor-like 7 (ARL7), two LXR target genes which play critical roles in cholesterol efflux
Title: MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.

an important role of LXRs in the coordinated regulation of lipid metabolic and inflammatory gene programs in macrophages
Title: Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.

The following Arl4c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl4c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58545	NM_177305.4 Latest version!	Mus musculus ADP-ribosylation factor-like 4C (Arl4c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl4c ( NM_177305.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796279.2 Mus musculus ADP-ribosylation factor-like 4C (Arl4c), mRNA.

Price & Availability↑

CloneID	OMu58545
Clone ID Related Accession (Same CDS sequence)	NM_177305.4
Accession Version	NM_177305.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 4C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU709624.1, BC055769.1 and AC115303.6. On May 21, 2009 this sequence version replaced NM_177305.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. COMPLETENESS: complete on the 3' end.

ATGGGCAACA TCTCCTCCAA CATCTCGGCC TTCCAGTCTC TGCACATCGT TATGCTGGGC 
TTGGACTCGG CCGGCAAGAC TACGGTGCTC TACCGGCTCA AGTTCAACGA ATTCGTGAAC 
ACTGTGCCCA CTATCGGCTT CAACACCGAG AAGATCAAAC TGAGCAACGG CACTGCCAAG 
GGCATCAGCT GCCACTTCTG GGACGTGGGC GGCCAGGAGA AGCTACGGCC GCTGTGGAAG 
TCCTACAGCC GCTGCACGGA CGGCATCATC TACGTGGTGG ATTCGGTGGA CGTGGACCGG 
CTGGAGGAGG CCAAGACGGA GCTGCACAAG GTGACCAAGT TTGCGGAGAA CCAGGGCACA 
CCGCTCCTGG TTATCGCCAA CAAGCAGGAT CTGCCTAAGT CGCTGCCGGT GGCCGAGATT 
GAGAAGCAAC TGGCGCTGCA CGAGCTCATC CCGGCCACCA CCTACCATGT CCAGCCGGCG 
TGCGCCATCA TCGGCGAGGG CCTCACCGAG GGCATGGACA AGCTCTATGA GATGATCCTG 
AAACGCAGGA AGTCTCTCAA GCAGAAGAAG AAGCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796279.2
CDS	528..1106
Translation	MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR

Target ORF information:

RefSeq Version	NM_177305.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 4C (Arl4c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177305.4

ORF Insert Sequence:

ATGGGCAACA TCTCCTCCAA CATCTCGGCC TTCCAGTCTC TGCACATCGT TATGCTGGGC 
TTGGACTCGG CCGGCAAGAC TACGGTGCTC TACCGGCTCA AGTTCAACGA ATTCGTGAAC 
ACTGTGCCCA CTATCGGCTT CAACACCGAG AAGATCAAAC TGAGCAACGG CACTGCCAAG 
GGCATCAGCT GCCACTTCTG GGACGTGGGC GGCCAGGAGA AGCTACGGCC GCTGTGGAAG 
TCCTACAGCC GCTGCACGGA CGGCATCATC TACGTGGTGG ATTCGGTGGA CGTGGACCGG 
CTGGAGGAGG CCAAGACGGA GCTGCACAAG GTGACCAAGT TTGCGGAGAA CCAGGGCACA 
CCGCTCCTGG TTATCGCCAA CAAGCAGGAT CTGCCTAAGT CGCTGCCGGT GGCCGAGATT 
GAGAAGCAAC TGGCGCTGCA CGAGCTCATC CCGGCCACCA CCTACCATGT CCAGCCGGCG 
TGCGCCATCA TCGGCGAGGG CCTCACCGAG GGCATGGACA AGCTCTATGA GATGATCCTG 
AAACGCAGGA AGTCTCTCAA GCAGAAGAAG AAGCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Immunity43(4)690-702(2015 Oct)
Ray JP,Staron MM,Shyer JA,Ho PC,Marshall HD,Gray SM,Laidlaw BJ,Araki K,Ahmed R,Kaech SM,Craft J

A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures.
The EMBO journal33(7)702-18(2014 Apr)
Matsumoto S,Fujii S,Sato A,Ibuka S,Kagawa Y,Ishii M,Kikuchi A

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES

MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.
FEBS letters586(10)1472-9(2012 May)
Sun D,Zhang J,Xie J,Wei W,Chen M,Zhao X