Foxi2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Foxi2
Entrez Gene ID	270004
Full Name	forkhead box I2
Synonyms	B130055A05Rik
General protein information	Preferred Names forkhead box I2 Names forkhead box protein I2 foxi2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F3

mRNA and Protein(s)

mRNA	Protein	Name
NM_183193.2	NP_899016.1	forkhead box protein I2
NM_183193.3	NP_899016.2	forkhead box protein I2

Pathways from BioSystems

Homologies

Homo sapiens (human)	FOXI2	NP_997309.2
	FOXI2	XP_001091576.1
Mus musculus (house mouse)	Foxi2	NP_899016.1
Pan troglodytes (chimpanzee)	FOXI2	XP_003312872.1
Bos taurus (cattle)	FOXI2	NP_001179878.1
Rattus norvegicus (Norway rat)	Foxi2	XP_341950.2
Canis lupus familiaris (dog)	FOXI2	XP_854369.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.
Birol O, Ohyama T, Edlund RK, Drakou K, Georgiades P, Groves AK
Developmental biology409(1)139-51(2016 Jan)

Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure.
Kimura-Yoshida C, Mochida K, Ellwanger K, Niehrs C, Matsuo I
EBioMedicine2(6)513-27(2015 Jun)

TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.
Shibata M, Blauvelt KE, Liem KF Jr, Garc?a-Garc?a MJ
Development (Cambridge, England)138(24)5333-43(2011 Dec)

Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling.
Mahoney Rogers AA, Zhang J, Shim K
Developmental biology353(1)94-104(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we describe the cloning and analysis of the murine Foxi2 gene, coding for a putative 311 amino acid protein
Title: Cloning and analysis of the murine Foxi2 transcription factor.

examined the expression patterns of the Foxi class genes from embryonic day 6.5 to 10.5; Foxi2 is expressed throughout the cranial ectoderm adjacent to the neural plate from the 4-somite stage, later becoming excluded from the otic placode
Title: Expression of mouse Foxi class genes in early craniofacial development.

The following Foxi2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxi2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08465	NM_183193.2 Latest version!	Mus musculus forkhead box I2 (Foxi2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu84490	NM_183193.3 Latest version!	Mus musculus forkhead box I2 (Foxi2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Foxi2 ( NM_183193.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_899016.1 Mus musculus forkhead box I2 (Foxi2), mRNA.

Price & Availability↑

CloneID	OMu08465
Clone ID Related Accession (Same CDS sequence)	NM_183193.2
Accession Version	NM_183193.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-09
Organism	Mus musculus(house mouse)
Product	forkhead box protein I2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK045276.1. On Apr 6, 2007 this sequence version replaced NM_183193.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK045276.1, BC096623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164137 [ECO:0000348] ##Evidence-Data-END##

ATGAGCTTCA GCACGGAGCC ACCTGCACCG GCCCAGGCCG GGGGAGAGCT GGACATGGCT 
GGGTTCTGCG ACAGCCTGGG TTCCTGCTCA GTCCCGCACG GCCTGACCCG GGCCATCGCG 
CATCCCCCGA GCTACGGCCG AACGGATCTG AGCTCTGGCC GGCGCCTGTG GGTGAACTCG 
GCCGCGCTCA GCCCGGCGCC CTACGCGACG GGACCAGGGC CGGCTCCATC CTACGCTGCA 
GCGACTCTCG CCGTCCCGGG TTCGCTTCTT GGCGCTTCAG GCGGTCTGGC AGGCGCTGAT 
CTCGCTTGGC TGAGCCTGTC CGGACAGCAG GAGCTGCTGA GGCTGGTACG GCCGCCCTAC 
TCCTACTCAG CACTGATCGC CATGGCCATC CAAAGCGCGC CGCTACGCAG GTTGACGCTC 
AGCCAGATCT ACCAGTATGT GGCGGGCAAC TTCCCCTTCT ACAAGCGCAG CAAGGCGGGC 
TGGCAGAACT CCATCCGCCA CAACCTGTCG CTCAATGATT GCTTCAAGAA GGTGCCCCGA 
GATGAGAACG ATCCAGGAAA AGGCAATTAT TGGACGCTGG ATCCAAACTG TGAGAAGATG 
TTTGACAATG GGAACTTCCG AAGGAAGAGG AGACGGAGAG GAGAGACTAG CGAGGCCGCT 
GTGCCTGGAG CCAGCAGCCC AGAGGGAACT GCACTGGAGC CCCGTGGCTC CACTCCCCAG 
GACCCACAGA CCTCACCATC CCCGTCTGAG GCCACCACTA CTTGCCTCTC GGGCTTCTCC 
ACGGCCATGG GAGCCCTGGC CGGCGGCTTT GGCGCCCTCC CTGATGGTCT GGCCCATGAC 
TTTTCTTTGC GAAGGCCACC ACCAACCGCG GCTGCCCACA GCCCTCAGAT TCCTAACACC 
GCGCCAGGCT TCGCTCCGGG CCATCAGACA GGGGCTACAG GCTTTAGGAT GGGGCACCTC 
ATCTACAGCC GGGATGGGAC TGAAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899016.1
CDS	19..1008
Translation	MSFSTEPPAPAQAGGELDMAGFCDSLGSCSVPHGLTRAIAHPPSYGRTDLSSGRRLWVNSAALSPAPYATGPGPAPSYAAATLAVPGSLLGASGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNFRRKRRRRGETSEAAVPGASSPEGTALEPRGSTPQDPQTSPSPSEATTTCLSGFSTAMGALAGGFGALPDGLAHDFSLRRPPPTAAAHSPQIPNTAPGFAPGHQTGATGFRMGHLIYSRDGTEV

Target ORF information:

RefSeq Version	NM_183193.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus forkhead box I2 (Foxi2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183193.2

ORF Insert Sequence:

ATGAGCTTCA GCACGGAGCC ACCTGCACCG GCCCAGGCCG GGGGAGAGCT GGACATGGCT 
GGGTTCTGCG ACAGCCTGGG TTCCTGCTCA GTCCCGCACG GCCTGACCCG GGCCATCGCG 
CATCCCCCGA GCTACGGCCG AACGGATCTG AGCTCTGGCC GGCGCCTGTG GGTGAACTCG 
GCCGCGCTCA GCCCGGCGCC CTACGCGACG GGACCAGGGC CGGCTCCATC CTACGCTGCA 
GCGACTCTCG CCGTCCCGGG TTCGCTTCTT GGCGCTTCAG GCGGTCTGGC AGGCGCTGAT 
CTCGCTTGGC TGAGCCTGTC CGGACAGCAG GAGCTGCTGA GGCTGGTACG GCCGCCCTAC 
TCCTACTCAG CACTGATCGC CATGGCCATC CAAAGCGCGC CGCTACGCAG GTTGACGCTC 
AGCCAGATCT ACCAGTATGT GGCGGGCAAC TTCCCCTTCT ACAAGCGCAG CAAGGCGGGC 
TGGCAGAACT CCATCCGCCA CAACCTGTCG CTCAATGATT GCTTCAAGAA GGTGCCCCGA 
GATGAGAACG ATCCAGGAAA AGGCAATTAT TGGACGCTGG ATCCAAACTG TGAGAAGATG 
TTTGACAATG GGAACTTCCG AAGGAAGAGG AGACGGAGAG GAGAGACTAG CGAGGCCGCT 
GTGCCTGGAG CCAGCAGCCC AGAGGGAACT GCACTGGAGC CCCGTGGCTC CACTCCCCAG 
GACCCACAGA CCTCACCATC CCCGTCTGAG GCCACCACTA CTTGCCTCTC GGGCTTCTCC 
ACGGCCATGG GAGCCCTGGC CGGCGGCTTT GGCGCCCTCC CTGATGGTCT GGCCCATGAC 
TTTTCTTTGC GAAGGCCACC ACCAACCGCG GCTGCCCACA GCCCTCAGAT TCCTAACACC 
GCGCCAGGCT TCGCTCCGGG CCATCAGACA GGGGCTACAG GCTTTAGGAT GGGGCACCTC 
ATCTACAGCC GGGATGGGAC TGAAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Foxi2 ( NM_183193.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_899016.2 Mus musculus forkhead box I2 (Foxi2), mRNA.

Price & Availability↑

CloneID	OMu84490
Clone ID Related Accession (Same CDS sequence)	NM_183193.3
Accession Version	NM_183193.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	forkhead box protein I2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC151838.6. On Feb 12, 2019 this sequence version replaced NM_183193.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK045276.1, BC096623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END##

ATGGCTGGGT TCTGCGACAG CCTGGGTTCC TGCTCAGTCC CGCACGGCCT GACCCGGGCC 
ATCGCGCATC CCCCGAGCTA CGGCCGAACG GATCTGAGCT CTGGCCGGCG CCTGTGGGTG 
AACTCGGCCG CGCTCAGCCC GGCGCCCTAC GCGACGGGAC CAGGGCCGGC TCCATCCTAC 
GCTGCAGCGA CTCTCGCCGT CCCGGGTTCG CTTCTTGGCG CTTCAGGCGG TCTGGCAGGC 
GCTGATCTCG CTTGGCTGAG CCTGTCCGGA CAGCAGGAGC TGCTGAGGCT GGTACGGCCG 
CCCTACTCCT ACTCAGCACT GATCGCCATG GCCATCCAAA GCGCGCCGCT ACGCAGGTTG 
ACGCTCAGCC AGATCTACCA GTATGTGGCG GGCAACTTCC CCTTCTACAA GCGCAGCAAG 
GCGGGCTGGC AGAACTCCAT CCGCCACAAC CTGTCGCTCA ATGATTGCTT CAAGAAGGTG 
CCCCGAGATG AGAACGATCC AGGAAAAGGC AATTATTGGA CGCTGGATCC AAACTGTGAG 
AAGATGTTTG ACAATGGGAA CTTCCGAAGG AAGAGGAGAC GGAGAGGAGA GACTAGCGAG 
GCCGCTGTGC CTGGAGCCAG CAGCCCAGAG GGAACTGCAC TGGAGCCCCG TGGCTCCACT 
CCCCAGGACC CACAGACCTC ACCATCCCCG TCTGAGGCCA CCACTACTTG CCTCTCGGGC 
TTCTCCACGG CCATGGGAGC CCTGGCCGGC GGCTTTGGCG CCCTCCCTGA TGGTCTGGCC 
CATGACTTTT CTTTGCGAAG GCCACCACCA ACCGCGGCTG CCCACAGCCC TCAGATTCCT 
AACACCGCGC CAGGCTTCGC TCCGGGCCAT CAGACAGGGG CTACAGGCTT TAGGATGGGG 
CACCTCATCT ACAGCCGGGA TGGGACTGAA GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899016.2
CDS	73..1008
Translation	MAGFCDSLGSCSVPHGLTRAIAHPPSYGRTDLSSGRRLWVNSAALSPAPYATGPGPAPSYAAATLAVPGSLLGASGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNFRRKRRRRGETSEAAVPGASSPEGTALEPRGSTPQDPQTSPSPSEATTTCLSGFSTAMGALAGGFGALPDGLAHDFSLRRPPPTAAAHSPQIPNTAPGFAPGHQTGATGFRMGHLIYSRDGTEV

Target ORF information:

RefSeq Version	NM_183193.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus forkhead box I2 (Foxi2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183193.3

ORF Insert Sequence:

ATGGCTGGGT TCTGCGACAG CCTGGGTTCC TGCTCAGTCC CGCACGGCCT GACCCGGGCC 
ATCGCGCATC CCCCGAGCTA CGGCCGAACG GATCTGAGCT CTGGCCGGCG CCTGTGGGTG 
AACTCGGCCG CGCTCAGCCC GGCGCCCTAC GCGACGGGAC CAGGGCCGGC TCCATCCTAC 
GCTGCAGCGA CTCTCGCCGT CCCGGGTTCG CTTCTTGGCG CTTCAGGCGG TCTGGCAGGC 
GCTGATCTCG CTTGGCTGAG CCTGTCCGGA CAGCAGGAGC TGCTGAGGCT GGTACGGCCG 
CCCTACTCCT ACTCAGCACT GATCGCCATG GCCATCCAAA GCGCGCCGCT ACGCAGGTTG 
ACGCTCAGCC AGATCTACCA GTATGTGGCG GGCAACTTCC CCTTCTACAA GCGCAGCAAG 
GCGGGCTGGC AGAACTCCAT CCGCCACAAC CTGTCGCTCA ATGATTGCTT CAAGAAGGTG 
CCCCGAGATG AGAACGATCC AGGAAAAGGC AATTATTGGA CGCTGGATCC AAACTGTGAG 
AAGATGTTTG ACAATGGGAA CTTCCGAAGG AAGAGGAGAC GGAGAGGAGA GACTAGCGAG 
GCCGCTGTGC CTGGAGCCAG CAGCCCAGAG GGAACTGCAC TGGAGCCCCG TGGCTCCACT 
CCCCAGGACC CACAGACCTC ACCATCCCCG TCTGAGGCCA CCACTACTTG CCTCTCGGGC 
TTCTCCACGG CCATGGGAGC CCTGGCCGGC GGCTTTGGCG CCCTCCCTGA TGGTCTGGCC 
CATGACTTTT CTTTGCGAAG GCCACCACCA ACCGCGGCTG CCCACAGCCC TCAGATTCCT 
AACACCGCGC CAGGCTTCGC TCCGGGCCAT CAGACAGGGG CTACAGGCTT TAGGATGGGG 
CACCTCATCT ACAGCCGGGA TGGGACTGAA GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.
Developmental biology409(1)139-51(2016 Jan)
Birol O,Ohyama T,Edlund RK,Drakou K,Georgiades P,Groves AK

Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure.
EBioMedicine2(6)513-27(2015 Jun)
Kimura-Yoshida C,Mochida K,Ellwanger K,Niehrs C,Matsuo I

TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.
Development (Cambridge, England)138(24)5333-43(2011 Dec)
Shibata M,Blauvelt KE,Liem KF Jr,Garc?a-Garc?a MJ

Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling.
Developmental biology353(1)94-104(2011 May)
Mahoney Rogers AA,Zhang J,Shim K