Lrrc8a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc8a
Entrez Gene ID	241296
Full Name	leucine rich repeat containing 8A
Synonyms	Lrrc8,mKIAA1437
General protein information	Preferred Names leucine rich repeat containing 8A Names volume-regulated anion channel subunit LRRC8A leucine-rich repeat-containing 8 leucine-rich repeat-containing protein 8A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_177725.4	NP_808393.1	volume-regulated anion channel subunit LRRC8A

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRRC8A	NP_001120717.1
Bos taurus (cattle)	LRRC8A	NP_001070275.1
Danio rerio (zebrafish)	lrrc8a	NP_001025120.1
Danio rerio (zebrafish)	si:ch211-236k19.7	XP_005165659.1
Xenopus tropicalis (tropical clawed frog)	lrrc8a	XP_004916747.1
	LRRC8A	XP_001109698.1
Mus musculus (house mouse)	Lrrc8a	NP_808393.1
Gallus gallus (chicken)	LOC100858917	XP_003642331.1
Gallus gallus (chicken)	LRRC8A	XP_415484.1
Pan troglodytes (chimpanzee)	LRRC8A	XP_520301.1
Canis lupus familiaris (dog)	LRRC8A	XP_005625321.1
Rattus norvegicus (Norway rat)	Lrrc8a	NP_001019953.1

Gene Ontology

The following Lrrc8a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc8a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06720	NM_177725.4 Latest version!	Mus musculus leucine rich repeat containing 8A VRAC subunit A (Lrrc8a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc8a ( NM_177725.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808393.1 Mus musculus leucine rich repeat containing 8A VRAC subunit A (Lrrc8a), mRNA.

Price & Availability↑

CloneID	OMu06720
Clone ID Related Accession (Same CDS sequence)	NM_177725.4
Accession Version	NM_177725.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	volume-regulated anion channel subunit LRRC8A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ444045.1 and AL845258.5. On Apr 28, 2009 this sequence version replaced NM_177725.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.4054321.1, SRR7345562.4108083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATTCCGG TGACAGAGCT CCGCTACTTT GCGGACACAC AGCCAGCATA CCGGATCCTG 
AAGCCTTGGT GGGATGTGTT CACTGATTAC ATCTCCATCG TCATGCTGAT GATTGCTGTC 
TTTGGAGGGA CGCTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGCAG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCGACGCCT GACACAGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGAC ACCAGTACAA CTACGTGGAT GCGGTGTGCT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTT CTGCACACCC TCATCTTCCT GGCCTGTAGC 
AACTTCTGGT TCAAGTTTCC ACGCACCAGT TCGAAGCTGG AACACTTTGT GTCTATCCTG 
CTCAAGTGCT TCGACTCACC GTGGACCACA CGGGCCCTGT CGGAGACAGT GGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AACGGGTCCA TGGACAAGAA GTCATCTACA 
GTCAGCGAGG ATGTGGAGGC CACCGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGATC GGAGACGGGC GTACTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCCCTGT TTGAGAAGGT GAAGAAGTTC CGGACTCACG TGGAGGAGGG GGACATTGTG 
TACCGCCTGT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCGCCCT CATCATCTGC 
TACACCGTCT ACTATGTGCA CAACATCAAG TTCGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCCC TGGCCACGCT CTTCAAGATC 
TTGGCATCCT TCTACATCAG CTTGGTCATC TTCTATGGCC TCATCTGCAT GTACACACTG 
TGGTGGATGC TGCGGCGCTC CCTCAAGAAG TACTCGTTCG AGTCGATCCG AGAGGAGAGC 
AGCTACAGTG ACATCCCCGA CGTCAAGAAC GACTTTGCCT TCATGTTGCA CCTCATCGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAAAAC 
AAGCTGCGCC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGCCTC 
ACCAAGAACG CCCAGGACAA GCTGGAGCTG CACCTGTTCA TGCTCAGCGG CATCCCGGAC 
ACTGTGTTTG ACCTGGTTGA GCTCGAGGTC CTGAAGCTGG AGCTGATACC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TGTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCTGC CCTGGCCTTC CTGCGGGAGA ACCTGCGGGC CCTGCACATC 
AAGTTCACGG ACATCAAGGA GATCCCGCTG TGGATCTACA GCCTGAAGAC GCTGGAGGAG 
CTGCACCTGA CGGGCAACCT GAGTGCAGAG AACAACCGCT ACATCGTCAT TGACGGGCTG 
CGGGAGCTCA AACGCCTCAA GGTGCTGCGA CTCAAGAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ATGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATTGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CGGAGCTAGA GCTGATCCGC 
TGTGACCTGG AGCGCATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATTGAC 
CTGAAGGACA ACAACCTCAA GACCATTGAG GAGATCATCA GCTTCCAGCA CCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATTGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TCGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT CCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTCCTC 
CCCGCCGACA TTGGCCTCCT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATT 
GAAGCGCTCC CCCCAGAGCT CTTCCAGTGT CGGAAGCTAC GGGCTCTACA CCTGGGCAAC 
AATGTACTGC AGTCGCTGCC CTCGAGAGTG GGCGAGCTGA CCAACCTGAC GCAGATCGAG 
CTTCGGGGCA ACCGGCTGGA ATGCCTGCCC GTGGAGCTGG GAGAGTGCCC CCTACTCAAG 
CGCAGCGGCC TGGTGGTGGA AGAGGACTTG TTCAGCACAC TGCCACCTGA GGTGAAGGAG 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808393.1
CDS	155..2587
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWAASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFALIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	NM_177725.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat containing 8A VRAC subunit A (Lrrc8a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177725.4

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTT GCGGACACAC AGCCAGCATA CCGGATCCTG 
AAGCCTTGGT GGGATGTGTT CACTGATTAC ATCTCCATCG TCATGCTGAT GATTGCTGTC 
TTTGGAGGGA CGCTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGCAG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCGACGCCT GACACAGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGAC ACCAGTACAA CTACGTGGAT GCGGTGTGCT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTT CTGCACACCC TCATCTTCCT GGCCTGTAGC 
AACTTCTGGT TCAAGTTTCC ACGCACCAGT TCGAAGCTGG AACACTTTGT GTCTATCCTG 
CTCAAGTGCT TCGACTCACC GTGGACCACA CGGGCCCTGT CGGAGACAGT GGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AACGGGTCCA TGGACAAGAA GTCATCTACA 
GTCAGCGAGG ATGTGGAGGC CACCGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGATC GGAGACGGGC GTACTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCCCTGT TTGAGAAGGT GAAGAAGTTC CGGACTCACG TGGAGGAGGG GGACATTGTG 
TACCGCCTGT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCGCCCT CATCATCTGC 
TACACCGTCT ACTATGTGCA CAACATCAAG TTCGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCCC TGGCCACGCT CTTCAAGATC 
TTGGCATCCT TCTACATCAG CTTGGTCATC TTCTATGGCC TCATCTGCAT GTACACACTG 
TGGTGGATGC TGCGGCGCTC CCTCAAGAAG TACTCGTTCG AGTCGATCCG AGAGGAGAGC 
AGCTACAGTG ACATCCCCGA CGTCAAGAAC GACTTTGCCT TCATGTTGCA CCTCATCGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAAAAC 
AAGCTGCGCC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGCCTC 
ACCAAGAACG CCCAGGACAA GCTGGAGCTG CACCTGTTCA TGCTCAGCGG CATCCCGGAC 
ACTGTGTTTG ACCTGGTTGA GCTCGAGGTC CTGAAGCTGG AGCTGATACC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TGTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCTGC CCTGGCCTTC CTGCGGGAGA ACCTGCGGGC CCTGCACATC 
AAGTTCACGG ACATCAAGGA GATCCCGCTG TGGATCTACA GCCTGAAGAC GCTGGAGGAG 
CTGCACCTGA CGGGCAACCT GAGTGCAGAG AACAACCGCT ACATCGTCAT TGACGGGCTG 
CGGGAGCTCA AACGCCTCAA GGTGCTGCGA CTCAAGAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ATGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATTGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CGGAGCTAGA GCTGATCCGC 
TGTGACCTGG AGCGCATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATTGAC 
CTGAAGGACA ACAACCTCAA GACCATTGAG GAGATCATCA GCTTCCAGCA CCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATTGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TCGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT CCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTCCTC 
CCCGCCGACA TTGGCCTCCT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATT 
GAAGCGCTCC CCCCAGAGCT CTTCCAGTGT CGGAAGCTAC GGGCTCTACA CCTGGGCAAC 
AATGTACTGC AGTCGCTGCC CTCGAGAGTG GGCGAGCTGA CCAACCTGAC GCAGATCGAG 
CTTCGGGGCA ACCGGCTGGA ATGCCTGCCC GTGGAGCTGG GAGAGTGCCC CCTACTCAAG 
CGCAGCGGCC TGGTGGTGGA AGAGGACTTG TTCAGCACAC TGCCACCTGA GGTGAAGGAG 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA