Itpkc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itpkc
Entrez Gene ID	233011
Full Name	inositol 1,4,5-trisphosphate 3-kinase C
Synonyms	9130023N17Rik
General protein information	Preferred Names inositol 1,4,5-trisphosphate 3-kinase C Names inositol-trisphosphate 3-kinase C IP3 3-kinase C IP3K C insP 3-kinase C
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_181593.3	NP_853624.1	inositol-trisphosphate 3-kinase C
NM_181593.2	NP_853624.1	inositol-trisphosphate 3-kinase C

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ITPKC	NP_001069479.1
	LOC703722	XP_001092036.1
Mus musculus (house mouse)	Itpkc	NP_853624.1
Xenopus tropicalis (tropical clawed frog)	itpkc	NP_001072256.1
Homo sapiens (human)	ITPKC	NP_079470.1
Canis lupus familiaris (dog)	ITPKC	XP_855312.2
Rattus norvegicus (Norway rat)	Itpkc	NP_835195.1
Pan troglodytes (chimpanzee)	ITPKC	XP_524271.2

Gene Ontology
Bibliography

Related articles in PubMed

Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice.
Scoumanne A, Molina-Ortiz P, Monteyne D, Perez-Morga D, Erneux C, Schurmans S
Advances in biological regulation621-10(2016 09)

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.
Dietrich JE, Panavaite L, Gunther S, Wennekamp S, Groner AC, Pigge A, Salvenmoser S, Trono D, Hufnagel L, Hiiragi T
EMBO reports16(8)1005-21(2015 Aug)

The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts.
Leyman A, Pouillon V, Bostan A, Schurmans S, Erneux C, Pesesse X
Cellular signalling19(7)1497-504(2007 Jul)

Bioinformatics and cellular signaling.
Papin J, Subramaniam S
Current opinion in biotechnology15(1)78-81(2004 Feb)

Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development.
Pouillon V, Hascakova-Bartova R, Pajak B, Adam E, Bex F, Dewaste V, Van Lint C, Leo O, Erneux C, Schurmans S
Nature immunology4(11)1136-43(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The expression of ITPKC in various ciliated tissues suggest a role for the enzyme either in the development or in the function of these specialized cellular structures.
Title: Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice.

These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6, at least in mouse embryonic fibroblasts.[Itpka, Itpkb, Itpkc]
Title: The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts.

The following Itpkc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itpkc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu08115	NM_181593.3 Latest version!	Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$398.30 $569.00
View Old Accession Versions >>
OMu08115	NM_181593.2	Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$398.30 $569.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itpkc ( NM_181593.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_853624.1 Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.

Price & Availability↑

CloneID	OMu08115
Clone ID Related Accession (Same CDS sequence)	NM_181593.3 , NM_181593.2
Accession Version	NM_181593.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-27
Organism	Mus musculus(house mouse)
Product	inositol-trisphosphate 3-kinase C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY275976.1 and BC053450.1. On Jun 9, 2018 this sequence version replaced NM_181593.2. ##Evidence-Data-START## Transcript exon combination :: BC053450.1, BC013227.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCGCT GCCCGTGCCG GGGGAGCCTG AGCGAGGCGG AGGCCGGCGC ACTGCCAGCC 
GAGGCCCGCA TGGGGCTGGA GGCGCTGCGA GGTGGGCGGC GGCGACAGCC TGGACTACAA 
CGACCTGGAC CGGGAGCAGG TGGCCCGACG GGACGGCCGG AGGGGGGCGG TCCCCGGGCC 
TGGATCGAGG AGTCCAGCCT CCACTCCGAG GCGGAGAGGA CCGACCTCGA GCCTGCGCCG 
TGTCCGAACG GTCCACAGGC AGAATCCTGT GGAGATGGAC ACGCGGAGTG CGAAGCAGCT 
GGCCTAGTAG TTGCGTCGGA GAAGCCCAGG CAAAATAAGG AGCTAGACGG GTCCAACCTC 
CAGACACATC CAAGAAGGAA CAGCCCCCTG GTTGAGATGG AGATGGCCGG TTCCTGGACA 
GATGGCTTTC GAACTGATCT TCACAGATCT GACCTCCAGT CTCGGCCAAA GAGAGCCAGC 
CTCTGTACCC AACCAGGGTT TGATGAGTCC TGGACCGAAC TGGACAGATC CGATATGTGG 
CAGACTCTGC CAGAGAGGGA CAACAAGCCC AGGGTTGATA ACCTTAGGAC CCACCATGGC 
GTGTCCAAAC TCCAAACTCA CCCAGTCTGC CTCTCACCAG AATCAAGTGC TGATAACTCC 
GGCAAAGAAT TGTCCGCGGA TGCTTCCAGG ACTCCACATG ACACCGACGG CTTCTGGATA 
GAGTCCCAAA CTGATGACTC TCTCAAAGGA CCTAGTACTC AGACAGCCTG CAGACAACCT 
GGGAGTGATG GTTTTTCCTC AAAAGACACT GAGAGTGCCT TGACTCAACC TGGCACTGAT 
GGCCTCCGGG ATGACAGCGT TTTGGGGGAG TCCAATGGAA ATGATCCATT AGATTTATCA 
GAGCCTGGAG AGTTGGTGAC TAACCTGTGC TCCCACCTGG AGTGCAGCTC CCTGTGTCCT 
GTGCCCCGCC TTATCATCAC CCCAGAGACT CCTGAACCTG AGGCCCAGCC GGTGGGACCC 
CAATCCCGGA TTGAGGGGGG CACTGGCGGC TTCTCTTCTG CCTCCTCTTT TGATGAATCT 
GAGGATGACT TGGTAGCCGG GGGCGGAGGT ACCAGCGATC CTGAGGACAG AGCTGGAAGC 
AAGCCCTGGA AGAAGCTGAA GACAGTTCTG AAGTACTCGC CCTTCGTGGT CTCCTTCCAT 
AAGCACTACT ATCCCTGGGT CCAGCTTTCC GGACACGCTG GGAACTTCCA GGCCGGTGAG 
GATGGTCGGA TTCTGAAACG TTTCTGTCAG TGTGAGCAGC GCAGCCTGGA GCTGCTGATG 
GGAGACCCCC TGCGGCCTTT TGTGCCTGCT TATTATGGCA TGGTGCAGCG GGATGGCCAG 
GCCTTCAACC AGATGGAAGA TCTCCTGGCA GACTTTGAGG GCCCCTCTAT CATGGACTGC 
AAGATGGGCA GCAGGACCTA CCTGGAAGAG GAGCTGGTGA AGGCCAGGGA ACGACCCAAG 
CCCCGGAAGG ATATGTATGA GAAGATGGTG GCAGTGGACC CCGGGGCTCC CACCCCAGAA 
GAGCATGCTC AGGGTGCCAT CACGAAGCCC CGATACATGC AGTGGAGGGA GACCCTGAGT 
TCAACTTCCA CGCTGGGCTT CCGGATTGAA GGCATCAAGA AGGCTGATGG GACCTGCAAC 
ACCAACTTCA AGAAGACACA GGCTCTGGAG CAGGTGACAA AGGTGTTAGA AGACTTTGTG 
AATGGGGACC TTGGAATCCT AAGAAAGTAC GTGGCGCGAC TGGAAGACCT CCGAGAGACT 
CTGGAAAATT CTCCCTTCTT CAAGACCCAC GAGGTAGTGG GCAGTTCCCT TCTCTTTGTG 
CATGACCACA CTGGCCTGGC CAAGGTCTGG ATGATTGACT TCGGCAAGAC AGTGGCCCTG 
CCTGACCACC AGATGCTCAG TCACAGGCTG CCTTGGACAG AGGGCAACCG TGAGGACGGC 
TACCTCTGGG GTCTGGACAA TTTGATCTGC CTCCTTCAGG GGCTGGCCCA GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_853624.1
CDS	131..2167
Translation	MRRCPCRGSLSEAEAGALPAEARMGLEALRGGRRRQPGLQRPGPGAGGPTGRPEGGGPRAWIEESSLHSEAERTDLEPAPCPNGPQAESCGDGHAECEAAGLVVASEKPRQNKELDGSNLQTHPRRNSPLVEMEMAGSWTDGFRTDLHRSDLQSRPKRASLCTQPGFDESWTELDRSDMWQTLPERDNKPRVDNLRTHHGVSKLQTHPVCLSPESSADNSGKELSADASRTPHDTDGFWIESQTDDSLKGPSTQTACRQPGSDGFSSKDTESALTQPGTDGLRDDSVLGESNGNDPLDLSEPGELVTNLCSHLECSSLCPVPRLIITPETPEPEAQPVGPQSRIEGGTGGFSSASSFDESEDDLVAGGGGTSDPEDRAGSKPWKKLKTVLKYSPFVVSFHKHYYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLELLMGDPLRPFVPAYYGMVQRDGQAFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPKPRKDMYEKMVAVDPGAPTPEEHAQGAITKPRYMQWRETLSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVNGDLGILRKYVARLEDLRETLENSPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQMLSHRLPWTEGNREDGYLWGLDNLICLLQGLAQS

Target ORF information:

RefSeq Version	NM_181593.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181593.3

ORF Insert Sequence:

ATGAGGCGCT GCCCGTGCCG GGGGAGCCTG AGCGAGGCGG AGGCCGGCGC ACTGCCAGCC 
GAGGCCCGCA TGGGGCTGGA GGCGCTGCGA GGTGGGCGGC GGCGACAGCC TGGACTACAA 
CGACCTGGAC CGGGAGCAGG TGGCCCGACG GGACGGCCGG AGGGGGGCGG TCCCCGGGCC 
TGGATCGAGG AGTCCAGCCT CCACTCCGAG GCGGAGAGGA CCGACCTCGA GCCTGCGCCG 
TGTCCGAACG GTCCACAGGC AGAATCCTGT GGAGATGGAC ACGCGGAGTG CGAAGCAGCT 
GGCCTAGTAG TTGCGTCGGA GAAGCCCAGG CAAAATAAGG AGCTAGACGG GTCCAACCTC 
CAGACACATC CAAGAAGGAA CAGCCCCCTG GTTGAGATGG AGATGGCCGG TTCCTGGACA 
GATGGCTTTC GAACTGATCT TCACAGATCT GACCTCCAGT CTCGGCCAAA GAGAGCCAGC 
CTCTGTACCC AACCAGGGTT TGATGAGTCC TGGACCGAAC TGGACAGATC CGATATGTGG 
CAGACTCTGC CAGAGAGGGA CAACAAGCCC AGGGTTGATA ACCTTAGGAC CCACCATGGC 
GTGTCCAAAC TCCAAACTCA CCCAGTCTGC CTCTCACCAG AATCAAGTGC TGATAACTCC 
GGCAAAGAAT TGTCCGCGGA TGCTTCCAGG ACTCCACATG ACACCGACGG CTTCTGGATA 
GAGTCCCAAA CTGATGACTC TCTCAAAGGA CCTAGTACTC AGACAGCCTG CAGACAACCT 
GGGAGTGATG GTTTTTCCTC AAAAGACACT GAGAGTGCCT TGACTCAACC TGGCACTGAT 
GGCCTCCGGG ATGACAGCGT TTTGGGGGAG TCCAATGGAA ATGATCCATT AGATTTATCA 
GAGCCTGGAG AGTTGGTGAC TAACCTGTGC TCCCACCTGG AGTGCAGCTC CCTGTGTCCT 
GTGCCCCGCC TTATCATCAC CCCAGAGACT CCTGAACCTG AGGCCCAGCC GGTGGGACCC 
CAATCCCGGA TTGAGGGGGG CACTGGCGGC TTCTCTTCTG CCTCCTCTTT TGATGAATCT 
GAGGATGACT TGGTAGCCGG GGGCGGAGGT ACCAGCGATC CTGAGGACAG AGCTGGAAGC 
AAGCCCTGGA AGAAGCTGAA GACAGTTCTG AAGTACTCGC CCTTCGTGGT CTCCTTCCAT 
AAGCACTACT ATCCCTGGGT CCAGCTTTCC GGACACGCTG GGAACTTCCA GGCCGGTGAG 
GATGGTCGGA TTCTGAAACG TTTCTGTCAG TGTGAGCAGC GCAGCCTGGA GCTGCTGATG 
GGAGACCCCC TGCGGCCTTT TGTGCCTGCT TATTATGGCA TGGTGCAGCG GGATGGCCAG 
GCCTTCAACC AGATGGAAGA TCTCCTGGCA GACTTTGAGG GCCCCTCTAT CATGGACTGC 
AAGATGGGCA GCAGGACCTA CCTGGAAGAG GAGCTGGTGA AGGCCAGGGA ACGACCCAAG 
CCCCGGAAGG ATATGTATGA GAAGATGGTG GCAGTGGACC CCGGGGCTCC CACCCCAGAA 
GAGCATGCTC AGGGTGCCAT CACGAAGCCC CGATACATGC AGTGGAGGGA GACCCTGAGT 
TCAACTTCCA CGCTGGGCTT CCGGATTGAA GGCATCAAGA AGGCTGATGG GACCTGCAAC 
ACCAACTTCA AGAAGACACA GGCTCTGGAG CAGGTGACAA AGGTGTTAGA AGACTTTGTG 
AATGGGGACC TTGGAATCCT AAGAAAGTAC GTGGCGCGAC TGGAAGACCT CCGAGAGACT 
CTGGAAAATT CTCCCTTCTT CAAGACCCAC GAGGTAGTGG GCAGTTCCCT TCTCTTTGTG 
CATGACCACA CTGGCCTGGC CAAGGTCTGG ATGATTGACT TCGGCAAGAC AGTGGCCCTG 
CCTGACCACC AGATGCTCAG TCACAGGCTG CCTTGGACAG AGGGCAACCG TGAGGACGGC 
TACCTCTGGG GTCTGGACAA TTTGATCTGC CTCCTTCAGG GGCTGGCCCA GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itpkc ( NM_181593.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_853624.1 Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.

Price & Availability↑

CloneID	OMu08115
Clone ID Related Accession (Same CDS sequence)	NM_181593.3 , NM_181593.2
Accession Version	NM_181593.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-12
Organism	Mus musculus(house mouse)
Product	inositol-trisphosphate 3-kinase C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC053450.1. On Jun 17, 2003 this sequence version replaced NM_181593.1. ##Evidence-Data-START## Transcript exon combination :: BC053450.1, BC013227.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGGCGCT GCCCGTGCCG GGGGAGCCTG AGCGAGGCGG AGGCCGGCGC ACTGCCAGCC 
GAGGCCCGCA TGGGGCTGGA GGCGCTGCGA GGTGGGCGGC GGCGACAGCC TGGACTACAA 
CGACCTGGAC CGGGAGCAGG TGGCCCGACG GGACGGCCGG AGGGGGGCGG TCCCCGGGCC 
TGGATCGAGG AGTCCAGCCT CCACTCCGAG GCGGAGAGGA CCGACCTCGA GCCTGCGCCG 
TGTCCGAACG GTCCACAGGC AGAATCCTGT GGAGATGGAC ACGCGGAGTG CGAAGCAGCT 
GGCCTAGTAG TTGCGTCGGA GAAGCCCAGG CAAAATAAGG AGCTAGACGG GTCCAACCTC 
CAGACACATC CAAGAAGGAA CAGCCCCCTG GTTGAGATGG AGATGGCCGG TTCCTGGACA 
GATGGCTTTC GAACTGATCT TCACAGATCT GACCTCCAGT CTCGGCCAAA GAGAGCCAGC 
CTCTGTACCC AACCAGGGTT TGATGAGTCC TGGACCGAAC TGGACAGATC CGATATGTGG 
CAGACTCTGC CAGAGAGGGA CAACAAGCCC AGGGTTGATA ACCTTAGGAC CCACCATGGC 
GTGTCCAAAC TCCAAACTCA CCCAGTCTGC CTCTCACCAG AATCAAGTGC TGATAACTCC 
GGCAAAGAAT TGTCCGCGGA TGCTTCCAGG ACTCCACATG ACACCGACGG CTTCTGGATA 
GAGTCCCAAA CTGATGACTC TCTCAAAGGA CCTAGTACTC AGACAGCCTG CAGACAACCT 
GGGAGTGATG GTTTTTCCTC AAAAGACACT GAGAGTGCCT TGACTCAACC TGGCACTGAT 
GGCCTCCGGG ATGACAGCGT TTTGGGGGAG TCCAATGGAA ATGATCCATT AGATTTATCA 
GAGCCTGGAG AGTTGGTGAC TAACCTGTGC TCCCACCTGG AGTGCAGCTC CCTGTGTCCT 
GTGCCCCGCC TTATCATCAC CCCAGAGACT CCTGAACCTG AGGCCCAGCC GGTGGGACCC 
CAATCCCGGA TTGAGGGGGG CACTGGCGGC TTCTCTTCTG CCTCCTCTTT TGATGAATCT 
GAGGATGACT TGGTAGCCGG GGGCGGAGGT ACCAGCGATC CTGAGGACAG AGCTGGAAGC 
AAGCCCTGGA AGAAGCTGAA GACAGTTCTG AAGTACTCGC CCTTCGTGGT CTCCTTCCAT 
AAGCACTACT ATCCCTGGGT CCAGCTTTCC GGACACGCTG GGAACTTCCA GGCCGGTGAG 
GATGGTCGGA TTCTGAAACG TTTCTGTCAG TGTGAGCAGC GCAGCCTGGA GCTGCTGATG 
GGAGACCCCC TGCGGCCTTT TGTGCCTGCT TATTATGGCA TGGTGCAGCG GGATGGCCAG 
GCCTTCAACC AGATGGAAGA TCTCCTGGCA GACTTTGAGG GCCCCTCTAT CATGGACTGC 
AAGATGGGCA GCAGGACCTA CCTGGAAGAG GAGCTGGTGA AGGCCAGGGA ACGACCCAAG 
CCCCGGAAGG ATATGTATGA GAAGATGGTG GCAGTGGACC CCGGGGCTCC CACCCCAGAA 
GAGCATGCTC AGGGTGCCAT CACGAAGCCC CGATACATGC AGTGGAGGGA GACCCTGAGT 
TCAACTTCCA CGCTGGGCTT CCGGATTGAA GGCATCAAGA AGGCTGATGG GACCTGCAAC 
ACCAACTTCA AGAAGACACA GGCTCTGGAG CAGGTGACAA AGGTGTTAGA AGACTTTGTG 
AATGGGGACC TTGGAATCCT AAGAAAGTAC GTGGCGCGAC TGGAAGACCT CCGAGAGACT 
CTGGAAAATT CTCCCTTCTT CAAGACCCAC GAGGTAGTGG GCAGTTCCCT TCTCTTTGTG 
CATGACCACA CTGGCCTGGC CAAGGTCTGG ATGATTGACT TCGGCAAGAC AGTGGCCCTG 
CCTGACCACC AGATGCTCAG TCACAGGCTG CCTTGGACAG AGGGCAACCG TGAGGACGGC 
TACCTCTGGG GTCTGGACAA TTTGATCTGC CTCCTTCAGG GGCTGGCCCA GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_853624.1
CDS	111..2147
Translation	MRRCPCRGSLSEAEAGALPAEARMGLEALRGGRRRQPGLQRPGPGAGGPTGRPEGGGPRAWIEESSLHSEAERTDLEPAPCPNGPQAESCGDGHAECEAAGLVVASEKPRQNKELDGSNLQTHPRRNSPLVEMEMAGSWTDGFRTDLHRSDLQSRPKRASLCTQPGFDESWTELDRSDMWQTLPERDNKPRVDNLRTHHGVSKLQTHPVCLSPESSADNSGKELSADASRTPHDTDGFWIESQTDDSLKGPSTQTACRQPGSDGFSSKDTESALTQPGTDGLRDDSVLGESNGNDPLDLSEPGELVTNLCSHLECSSLCPVPRLIITPETPEPEAQPVGPQSRIEGGTGGFSSASSFDESEDDLVAGGGGTSDPEDRAGSKPWKKLKTVLKYSPFVVSFHKHYYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLELLMGDPLRPFVPAYYGMVQRDGQAFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPKPRKDMYEKMVAVDPGAPTPEEHAQGAITKPRYMQWRETLSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVNGDLGILRKYVARLEDLRETLENSPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQMLSHRLPWTEGNREDGYLWGLDNLICLLQGLAQS

Target ORF information:

RefSeq Version	NM_181593.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol 1,4,5-trisphosphate 3-kinase C (Itpkc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181593.2

ORF Insert Sequence:

ATGAGGCGCT GCCCGTGCCG GGGGAGCCTG AGCGAGGCGG AGGCCGGCGC ACTGCCAGCC 
GAGGCCCGCA TGGGGCTGGA GGCGCTGCGA GGTGGGCGGC GGCGACAGCC TGGACTACAA 
CGACCTGGAC CGGGAGCAGG TGGCCCGACG GGACGGCCGG AGGGGGGCGG TCCCCGGGCC 
TGGATCGAGG AGTCCAGCCT CCACTCCGAG GCGGAGAGGA CCGACCTCGA GCCTGCGCCG 
TGTCCGAACG GTCCACAGGC AGAATCCTGT GGAGATGGAC ACGCGGAGTG CGAAGCAGCT 
GGCCTAGTAG TTGCGTCGGA GAAGCCCAGG CAAAATAAGG AGCTAGACGG GTCCAACCTC 
CAGACACATC CAAGAAGGAA CAGCCCCCTG GTTGAGATGG AGATGGCCGG TTCCTGGACA 
GATGGCTTTC GAACTGATCT TCACAGATCT GACCTCCAGT CTCGGCCAAA GAGAGCCAGC 
CTCTGTACCC AACCAGGGTT TGATGAGTCC TGGACCGAAC TGGACAGATC CGATATGTGG 
CAGACTCTGC CAGAGAGGGA CAACAAGCCC AGGGTTGATA ACCTTAGGAC CCACCATGGC 
GTGTCCAAAC TCCAAACTCA CCCAGTCTGC CTCTCACCAG AATCAAGTGC TGATAACTCC 
GGCAAAGAAT TGTCCGCGGA TGCTTCCAGG ACTCCACATG ACACCGACGG CTTCTGGATA 
GAGTCCCAAA CTGATGACTC TCTCAAAGGA CCTAGTACTC AGACAGCCTG CAGACAACCT 
GGGAGTGATG GTTTTTCCTC AAAAGACACT GAGAGTGCCT TGACTCAACC TGGCACTGAT 
GGCCTCCGGG ATGACAGCGT TTTGGGGGAG TCCAATGGAA ATGATCCATT AGATTTATCA 
GAGCCTGGAG AGTTGGTGAC TAACCTGTGC TCCCACCTGG AGTGCAGCTC CCTGTGTCCT 
GTGCCCCGCC TTATCATCAC CCCAGAGACT CCTGAACCTG AGGCCCAGCC GGTGGGACCC 
CAATCCCGGA TTGAGGGGGG CACTGGCGGC TTCTCTTCTG CCTCCTCTTT TGATGAATCT 
GAGGATGACT TGGTAGCCGG GGGCGGAGGT ACCAGCGATC CTGAGGACAG AGCTGGAAGC 
AAGCCCTGGA AGAAGCTGAA GACAGTTCTG AAGTACTCGC CCTTCGTGGT CTCCTTCCAT 
AAGCACTACT ATCCCTGGGT CCAGCTTTCC GGACACGCTG GGAACTTCCA GGCCGGTGAG 
GATGGTCGGA TTCTGAAACG TTTCTGTCAG TGTGAGCAGC GCAGCCTGGA GCTGCTGATG 
GGAGACCCCC TGCGGCCTTT TGTGCCTGCT TATTATGGCA TGGTGCAGCG GGATGGCCAG 
GCCTTCAACC AGATGGAAGA TCTCCTGGCA GACTTTGAGG GCCCCTCTAT CATGGACTGC 
AAGATGGGCA GCAGGACCTA CCTGGAAGAG GAGCTGGTGA AGGCCAGGGA ACGACCCAAG 
CCCCGGAAGG ATATGTATGA GAAGATGGTG GCAGTGGACC CCGGGGCTCC CACCCCAGAA 
GAGCATGCTC AGGGTGCCAT CACGAAGCCC CGATACATGC AGTGGAGGGA GACCCTGAGT 
TCAACTTCCA CGCTGGGCTT CCGGATTGAA GGCATCAAGA AGGCTGATGG GACCTGCAAC 
ACCAACTTCA AGAAGACACA GGCTCTGGAG CAGGTGACAA AGGTGTTAGA AGACTTTGTG 
AATGGGGACC TTGGAATCCT AAGAAAGTAC GTGGCGCGAC TGGAAGACCT CCGAGAGACT 
CTGGAAAATT CTCCCTTCTT CAAGACCCAC GAGGTAGTGG GCAGTTCCCT TCTCTTTGTG 
CATGACCACA CTGGCCTGGC CAAGGTCTGG ATGATTGACT TCGGCAAGAC AGTGGCCCTG 
CCTGACCACC AGATGCTCAG TCACAGGCTG CCTTGGACAG AGGGCAACCG TGAGGACGGC 
TACCTCTGGG GTCTGGACAA TTTGATCTGC CTCCTTCAGG GGCTGGCCCA GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice.
Advances in biological regulation621-10(2016 09)
Scoumanne A,Molina-Ortiz P,Monteyne D,Perez-Morga D,Erneux C,Schurmans S

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.
EMBO reports16(8)1005-21(2015 Aug)
Dietrich JE,Panavaite L,Gunther S,Wennekamp S,Groner AC,Pigge A,Salvenmoser S,Trono D,Hufnagel L,Hiiragi T

The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts.
Cellular signalling19(7)1497-504(2007 Jul)
Leyman A,Pouillon V,Bostan A,Schurmans S,Erneux C,Pesesse X

Bioinformatics and cellular signaling.
Current opinion in biotechnology15(1)78-81(2004 Feb)
Papin J,Subramaniam S

Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development.
Nature immunology4(11)1136-43(2003 Nov)
Pouillon V,Hascakova-Bartova R,Pajak B,Adam E,Bex F,Dewaste V,Van Lint C,Leo O,Erneux C,Schurmans S

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Itpkc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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