Uts2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uts2b
Entrez Gene ID	224065
Full Name	urotensin 2B
Synonyms	Gm538,U2B,Urp,Uts2d
General protein information	Preferred Names urotensin 2B Names urotensin-2B U-IIB UIIB urotensin II-related peptide urotensin IIB urotensin-2 domain-containing protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B2

mRNA and Protein(s)

mRNA	Protein	Name
NM_198166.3	NP_937809.1	urotensin-2B precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	UTS2B	NP_937795.2
Bos taurus (cattle)	UTS2B	XP_002684880.1
	UTS2D	XP_001094399.1
Pan troglodytes (chimpanzee)	UTS2D	XP_001161501.1
Mus musculus (house mouse)	Uts2b	NP_937809.1
Gallus gallus (chicken)	UTS2D	NP_996872.1
Rattus norvegicus (Norway rat)	Uts2b	NP_937766.1
Canis lupus familiaris (dog)	UTS2B	XP_850358.2
Xenopus tropicalis (tropical clawed frog)	uts2b	NP_001120467.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.
Dykes IM, van Bueren KL, Ashmore RJ, Floss T, Wurst W, Szumska D, Bhattacharya S, Scambler PJ
Circulation research115(1)23-31(2014 Jun)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Transcriptional profiling of the megabladder mouse: a unique model of bladder dysmorphogenesis.
Singh S, Robinson M, Ismail I, Saha M, Auer H, Kornacker K, Robinson ML, Bates CM, McHugh KM
Developmental dynamics : an official publication of the American Association of Anatomists237(1)170-86(2008 Jan)

A novel hypothalamic neuroendocrine peptide: URP (urotensin-II-related peptide)?
Egginger JG, Calas A
Comptes rendus biologies328(8)724-31(2005 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

novel hypothalamic neuroendocrine peptide co-localized and possible co-released with gonadotropin releasing hormone
Title: A novel hypothalamic neuroendocrine peptide: URP (urotensin-II-related peptide)?

URP is the endogenous and functional ligand for UII receptor in the mouse
Title: Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain.

The following Uts2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uts2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08868	NM_198166.3 Latest version!	Mus musculus urotensin 2B (Uts2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uts2b ( NM_198166.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_937809.1 Mus musculus urotensin 2B (Uts2b), mRNA.

Price & Availability↑

CloneID	OMu08868
Clone ID Related Accession (Same CDS sequence)	NM_198166.3
Accession Version	NM_198166.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	urotensin-2B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB611261.1, AB116020.1, AV144685.2 and AW490879.1. On Mar 24, 2005 this sequence version replaced NM_198166.2. ##Evidence-Data-START## Transcript exon combination :: CO039816.1, BB611261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTCT TTTCAACCTC TCTCTGGTGT GGACTCCTGA CTTTGTTGTC TGTAATGAAC 
CTTTTCAAAT CTGTGCGTGG ACGGCCACAT CTGAGCTCAG GACATGAGTT GTTTCCAGCT 
AAAGAACATG CAGCTCAAGA GAAGTTGACC CGAAATCCTG GTTTACAGAG GCCCTTCCAC 
GCTGGTGGAG ATCTTCCCAG CAAACTGGAA GAACTTAGAC AGGTAAAGAA GTTGAGAGAC 
TGGATTATGG AAGCAAAGAA CACTGGGCTG TCCAATGCTT TAGACAATTT ATCTTCTTCT 
CACACTAAAA AACGAGCTTG TTTTTGGAAG TACTGTGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937809.1
CDS	104..445
Translation	MKVFSTSLWCGLLTLLSVMNLFKSVRGRPHLSSGHELFPAKEHAAQEKLTRNPGLQRPFHAGGDLPSKLEELRQVKKLRDWIMEAKNTGLSNALDNLSSSHTKKRACFWKYCV

Target ORF information:

RefSeq Version	NM_198166.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus urotensin 2B (Uts2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198166.3

ORF Insert Sequence:

ATGAAGGTCT TTTCAACCTC TCTCTGGTGT GGACTCCTGA CTTTGTTGTC TGTAATGAAC 
CTTTTCAAAT CTGTGCGTGG ACGGCCACAT CTGAGCTCAG GACATGAGTT GTTTCCAGCT 
AAAGAACATG CAGCTCAAGA GAAGTTGACC CGAAATCCTG GTTTACAGAG GCCCTTCCAC 
GCTGGTGGAG ATCTTCCCAG CAAACTGGAA GAACTTAGAC AGGTAAAGAA GTTGAGAGAC 
TGGATTATGG AAGCAAAGAA CACTGGGCTG TCCAATGCTT TAGACAATTT ATCTTCTTCT 
CACACTAAAA AACGAGCTTG TTTTTGGAAG TACTGTGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.
Circulation research115(1)23-31(2014 Jun)
Dykes IM,van Bueren KL,Ashmore RJ,Floss T,Wurst W,Szumska D,Bhattacharya S,Scambler PJ

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Transcriptional profiling of the megabladder mouse: a unique model of bladder dysmorphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists237(1)170-86(2008 Jan)
Singh S,Robinson M,Ismail I,Saha M,Auer H,Kornacker K,Robinson ML,Bates CM,McHugh KM

A novel hypothalamic neuroendocrine peptide: URP (urotensin-II-related peptide)?
Comptes rendus biologies328(8)724-31(2005 Aug)
Egginger JG,Calas A