Tgoln1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tgoln1
Entrez Gene ID	22134
Full Name	trans-golgi network protein
Synonyms	AU015504,D6Ertd384e,TGN38,TGN38A,Ttgn1
General protein information	Preferred Names trans-golgi network protein Names trans-Golgi network integral membrane protein 1 trans-golgi network protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 C1\|6 32.27 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009443.3	NP_033469.1	trans-Golgi network integral membrane protein 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tgoln1	NP_033469.1
Rattus norvegicus (Norway rat)	Tgoln2	NP_620195.1

Gene Ontology
Bibliography

Related articles in PubMed

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.
Zhang D, Marlin MC, Liang Z, Ahmad M, Ashpole NM, Sonntag WE, Zhao ZJ, Li G
The Journal of biological chemistry291(46)23895-23905(2016 Nov)

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
Urresti J, Ruiz-Meana M, Coccia E, Ar?valo JC, Castellano J, Fern?ndez-Sanz C, Galenkamp KM, Planells-Ferrer L, Moubarak RS, Llecha-Cano N, Reix S, Garc?a-Dorado D, Barneda-Zahonero B, Comella JX
The Journal of biological chemistry291(3)1221-34(2016 Jan)

TGN38 is required for the metaphase I/anaphase I transition and asymmetric cell division during mouse oocyte meiotic maturation.
Chen L, Ge ZJ, Wang ZB, Sun T, Ouyang YC, Sun QY, Sun YP
Cell cycle (Georgetown, Tex.)13(17)2723-32(2014)

Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.
Tamaki H, Sanda M, Katsumata O, Hara Y, Fukaya M, Sakagami H
FEBS letters586(19)3064-70(2012 Sep)

Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.
Valkova C, Albrizio M, R?der IV, Schwake M, Betto R, Rudolf R, Kaether C
Proceedings of the National Academy of Sciences of the United States of America108(2)621-5(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGN38 may regulate the metaphase I/anaphase I transition and asymmetric cell division in mouse oocytes.
Title: TGN38 is required for the metaphase I/anaphase I transition and asymmetric cell division during mouse oocyte meiotic maturation.

The following Tgoln1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tgoln1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04162	NM_009443.3 Latest version!	Mus musculus trans-golgi network protein (Tgoln1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tgoln1 ( NM_009443.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033469.1 Mus musculus trans-golgi network protein (Tgoln1), mRNA.

Price & Availability↑

CloneID	OMu04162
Clone ID Related Accession (Same CDS sequence)	NM_009443.3
Accession Version	NM_009443.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	trans-Golgi network integral membrane protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK076586.1 and AC125039.4. On or before Nov 25, 2008 this sequence version replaced XM_001471627.1, XM_001471628.1, NM_009443.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK161242.1, SRR1660813.34145.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGTTCC AGGTTGCGTT GCTCCTGCTG AGTGTCGCGG TGGCGAGAGC TCTGCCGTCC 
GTTTATAAGA GAGACGCCGA CTCAGGTGAC TCTCAGAATC CTCCGAATCA GCCTTCCAAA 
CAGTCCTCCA CTCCCCTGCC TTCTTCTAAC CAGGTAAAGA CTACAAGGCC GACCGACGGT 
CAGGGGCAGA AGTCAGATAA AAAAGACCAG GACAAGACGA CTTTGGCAGC AGTTTCCAGT 
AAGGCGGAAT CTGGGCCGCG GACCGCCGCG ACCGATCACA GTTTGGGTGA TTCCAGAAGG 
CAGCCCGAGA AAACGGATGC CGAGTTGAAC GAAACTGCGC GGCCCCTCTC ACCAGTCAAC 
CCCAAACTGG AAAAGTCTGA TCAGAGCTCC ACAGAAGATT CAGGCAAGCC CACAGGAGGT 
AATTCTGGCA AGCCCACAGG AGGTGATTCT GGCAAGCCCA CAGAAGCTGG TTCGAATAAG 
GCCACAGAAG ATGATTCTGG CAAGTCCACG AAAGTTGATT TGGACAAGCC CACCTCCAAA 
ATCTCCCCAG ATACGGAGAC TTCGAAGACT GACAAAGTCC AGCCAACTGA AAAAGGACAA 
AAACCAACAC TTACTTCCAA AACTGAATCT GGGGAAACAC TGGCAGGGGA CTCTGACTTC 
TCTTTAAAGC CAGAGAAAGG AGATAAGTCT TCAGAGCCTA CTGAAGACGT GGAAACCAAG 
GAGATTGAAG AGGGTGACAC AGAGCCGGAA GAAGGCTCAC CACTTGAAGA AGAGAATGAA 
AAGGTGCCGG GCCCTTCCTC CAGTGAGAAC CAAGAGGGGA CACTTACAGA CTCTATGAAG 
AATGAGAAGG ATGATCTTTA TAAGGACAGT TCTGGAAACA CCAGTGCAGA GAGCAGCCAC 
TTCTTTGCAT ATCTAGTGAC CGCTGCTGTT CTTGTTGCTG TCCTCTATAT TGCTTACCAC 
AACAAACGAA AGATTATTGC TTTTGCTCTG GAAGGGAAAA GATCCAAAGT CACTCGGAGG 
CCAAAGGCCA GTGACTACCA ACGTTTGAAC CTAAAGCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033469.1
CDS	279..1340
Translation	MRFQVALLLLSVAVARALPSVYKRDADSGDSQNPPNQPSKQSSTPLPSSNQVKTTRPTDGQGQKSDKKDQDKTTLAAVSSKAESGPRTAATDHSLGDSRRQPEKTDAELNETARPLSPVNPKLEKSDQSSTEDSGKPTGGNSGKPTGGDSGKPTEAGSNKATEDDSGKSTKVDLDKPTSKISPDTETSKTDKVQPTEKGQKPTLTSKTESGETLAGDSDFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVPGPSSSENQEGTLTDSMKNEKDDLYKDSSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKRSKVTRRPKASDYQRLNLKL

Target ORF information:

RefSeq Version	NM_009443.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus trans-golgi network protein (Tgoln1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009443.3

ORF Insert Sequence:

ATGCGGTTCC AGGTTGCGTT GCTCCTGCTG AGTGTCGCGG TGGCGAGAGC TCTGCCGTCC 
GTTTATAAGA GAGACGCCGA CTCAGGTGAC TCTCAGAATC CTCCGAATCA GCCTTCCAAA 
CAGTCCTCCA CTCCCCTGCC TTCTTCTAAC CAGGTAAAGA CTACAAGGCC GACCGACGGT 
CAGGGGCAGA AGTCAGATAA AAAAGACCAG GACAAGACGA CTTTGGCAGC AGTTTCCAGT 
AAGGCGGAAT CTGGGCCGCG GACCGCCGCG ACCGATCACA GTTTGGGTGA TTCCAGAAGG 
CAGCCCGAGA AAACGGATGC CGAGTTGAAC GAAACTGCGC GGCCCCTCTC ACCAGTCAAC 
CCCAAACTGG AAAAGTCTGA TCAGAGCTCC ACAGAAGATT CAGGCAAGCC CACAGGAGGT 
AATTCTGGCA AGCCCACAGG AGGTGATTCT GGCAAGCCCA CAGAAGCTGG TTCGAATAAG 
GCCACAGAAG ATGATTCTGG CAAGTCCACG AAAGTTGATT TGGACAAGCC CACCTCCAAA 
ATCTCCCCAG ATACGGAGAC TTCGAAGACT GACAAAGTCC AGCCAACTGA AAAAGGACAA 
AAACCAACAC TTACTTCCAA AACTGAATCT GGGGAAACAC TGGCAGGGGA CTCTGACTTC 
TCTTTAAAGC CAGAGAAAGG AGATAAGTCT TCAGAGCCTA CTGAAGACGT GGAAACCAAG 
GAGATTGAAG AGGGTGACAC AGAGCCGGAA GAAGGCTCAC CACTTGAAGA AGAGAATGAA 
AAGGTGCCGG GCCCTTCCTC CAGTGAGAAC CAAGAGGGGA CACTTACAGA CTCTATGAAG 
AATGAGAAGG ATGATCTTTA TAAGGACAGT TCTGGAAACA CCAGTGCAGA GAGCAGCCAC 
TTCTTTGCAT ATCTAGTGAC CGCTGCTGTT CTTGTTGCTG TCCTCTATAT TGCTTACCAC 
AACAAACGAA AGATTATTGC TTTTGCTCTG GAAGGGAAAA GATCCAAAGT CACTCGGAGG 
CCAAAGGCCA GTGACTACCA ACGTTTGAAC CTAAAGCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.
The Journal of biological chemistry291(46)23895-23905(2016 Nov)
Zhang D,Marlin MC,Liang Z,Ahmad M,Ashpole NM,Sonntag WE,Zhao ZJ,Li G

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
The Journal of biological chemistry291(3)1221-34(2016 Jan)
Urresti J,Ruiz-Meana M,Coccia E,Ar?valo JC,Castellano J,Fern?ndez-Sanz C,Galenkamp KM,Planells-Ferrer L,Moubarak RS,Llecha-Cano N,Reix S,Garc?a-Dorado D,Barneda-Zahonero B,Comella JX

TGN38 is required for the metaphase I/anaphase I transition and asymmetric cell division during mouse oocyte meiotic maturation.
Cell cycle (Georgetown, Tex.)13(17)2723-32(2014)
Chen L,Ge ZJ,Wang ZB,Sun T,Ouyang YC,Sun QY,Sun YP

Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.
FEBS letters586(19)3064-70(2012 Sep)
Tamaki H,Sanda M,Katsumata O,Hara Y,Fukaya M,Sakagami H

Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.
Proceedings of the National Academy of Sciences of the United States of America108(2)621-5(2011 Jan)
Valkova C,Albrizio M,R?der IV,Schwake M,Betto R,Rudolf R,Kaether C