| Gene Symbol | Tgfbr1 |
| Entrez Gene ID | 21812 |
| Full Name | transforming growth factor, beta receptor I |
| Synonyms | ALK5,AU017191,Alk-5,ESK2,TGFR-1,TbetaR-I,TbetaRI |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome | |
| Summary | This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]. |







































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