Cdc73 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdc73
Entrez Gene ID	214498
Full Name	cell division cycle 73, Paf1/RNA polymerase II complex component
Synonyms	8430414L16Rik,C130030P16Rik,C81219,Hrpt2
General protein information	Preferred Names cell division cycle 73, Paf1/RNA polymerase II complex component Names parafibromin cell division cycle protein 73 homolog hyperparathyroidism 2 protein homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 F\|1 62.52 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_145991.1	NP_666103.1	parafibromin
NM_145991.2	NP_666103.1	parafibromin
XM_006529365.1	XP_006529428.1	parafibromin isoform X1
XM_006529365.2	XP_006529428.1	parafibromin isoform X1
XM_006529366.3	XP_006529429.1	parafibromin isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CDC73	NP_001178201.1
Oryza sativa (rice)	Os03g0664700	NP_001050838.1
Pan troglodytes (chimpanzee)	CDC73	XP_001167188.1
Mus musculus (house mouse)	Cdc73	NP_666103.1
Rattus norvegicus (Norway rat)	Cdc73	NP_001019940.1
Danio rerio (zebrafish)	cdc73	NP_956642.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008885	XP_552757.1
Drosophila melanogaster (fruit fly)	hyx	NP_649863.1
Caenorhabditis elegans (roundworm)	F35F11.1	NP_500465.3
Xenopus tropicalis (tropical clawed frog)	cdc73	NP_001016031.2
	CDC73	XP_001112553.1
Gallus gallus (chicken)	CDC73	NP_001026436.1
Homo sapiens (human)	CDC73	NP_078805.3
Canis lupus familiaris (dog)	CDC73	NP_001074976.1
Arabidopsis thaliana (thale cress)	PHP	NP_188898.1

Gene Ontology
Bibliography

Related articles in PubMed

Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome.
Walls GV, Stevenson M, Lines KE, Newey PJ, Reed AAC, Bowl MR, Jeyabalan J, Harding B, Bradley KJ, Manek S, Chen J, Wang P, Williams BO, Teh BT, Thakker RV
Oncogene36(28)4025-4036(2017 Jul)

Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover.
Droscha CJ, Diegel CR, Ethen NJ, Burgers TA, McDonald MJ, Maupin KA, Naidu AS, Wang P, Teh BT, Williams BO
Bone9868-78(2017 05)

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Osipovich AB, Gangula R, Vianna PG, Magnuson MA
Development (Cambridge, England)143(24)4595-4607(2016 12)

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I
Nature cell biology18(11)1127-1138(2016 Nov)

MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
Muntean AG, Chen W, Jones M, Granowicz EM, Maillard I, Hess JL
Blood122(11)1914-22(2013 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Uterine neoplasms, myometria and jaw bones of Cdc73(+/-) mice had increased proliferation rates that were 2-fold higher than in Cdc73(+/+) mice.
Title: Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome.

These results aid in our understanding of the role parafibromin plays within transcriptional regulation, terminal differentiation, and bone homeostasis
Title: Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover.

Data indicate that isruption of the MLL-PAFc subunit, Cdc73 (Hrpt2) interaction selectively inhibits the proliferation of MLL leukemic cells.
Title: MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.

Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation
Title: Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics.

Expression of Hrpt2 and parafibromin is pivotal in mammalian development and survival in adults and that these functions are likely mediated by the transcriptional regulation of growth factors.
Title: Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.

The following Cdc73 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc73 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu28078	XM_006529366.3 Latest version!	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu28077	XM_006529365.2 Latest version!	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu17630	NM_145991.2 Latest version!	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
View Old Accession Versions >>
OMu17630	NM_145991.1	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu28077	XM_006529365.1	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdc73 ( XM_006529365.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529428.1 Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu28077
Clone ID Related Accession (Same CDS sequence)	XM_006529365.1 , XM_006529365.2
Accession Version	XM_006529365.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	parafibromin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGTCTTTTT CTTGATGGAT GTTTCTTTTA GTGTTGTTCT TCTTGTCTTT 
CCTGCTTCTC ATTTCCTCTG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529428.1
CDS	265..1311
Translation	MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTVFFLMDVSFSVVLLVFPASHFLCE

Target ORF information:

RefSeq Version	XM_006529365.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529365.1

ORF Insert Sequence:

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGTCTTTTT CTTGATGGAT GTTTCTTTTA GTGTTGTTCT TCTTGTCTTT 
CCTGCTTCTC ATTTCCTCTG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc73 ( XM_006529366.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529429.1 Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu28078
Clone ID Related Accession (Same CDS sequence)	XM_006529366.3
Accession Version	XM_006529366.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	parafibromin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006529366.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGAGTTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529429.1
CDS	265..1245
Translation	MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTSF

Target ORF information:

RefSeq Version	XM_006529366.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529366.3

ORF Insert Sequence:

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGAGTTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc73 ( XM_006529365.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529428.1 Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu28077
Clone ID Related Accession (Same CDS sequence)	XM_006529365.1 , XM_006529365.2
Accession Version	XM_006529365.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	parafibromin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529365.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGTCTTTTT CTTGATGGAT GTTTCTTTTA GTGTTGTTCT TCTTGTCTTT 
CCTGCTTCTC ATTTCCTCTG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529428.1
CDS	265..1311
Translation	MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTVFFLMDVSFSVVLLVFPASHFLCE

Target ORF information:

RefSeq Version	XM_006529365.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529365.2

ORF Insert Sequence:

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGTCTTTTT CTTGATGGAT GTTTCTTTTA GTGTTGTTCT TCTTGTCTTT 
CCTGCTTCTC ATTTCCTCTG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc73 ( NM_145991.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666103.1 Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.

Price & Availability↑

CloneID	OMu17630
Clone ID Related Accession (Same CDS sequence)	NM_145991.1 , NM_145991.2
Accession Version	NM_145991.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	parafibromin
Comment

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGAAGGTGC ATCTGCTCGT AAGACTCAAA CTCCTGCAGC CCAGCCTGTA 
CCTAGACCAG TGTCTCAAGC CAGACCCCCC CCAAATCAGA AGAAAGGGTC ACGGACACCC 
ATTATTATTA TTCCTGCAGC TACCACTTCT TTAATAACTA TGCTTAATGC AAAAGACCTT 
CTACAGGATC TGAAATTTGT CCCATCAGAT GAGAAGAAGA AACAGGGTTG TCAACGAGAA 
AATGAAACAC TAATACAGAG AAGAAAAGAC CAGATGCAAC CAGGGGGCAC AGCAATTAGT 
GTCACAGTAC CTTACAGAGT AGTAGACCAG CCCCTGAAAC TTATGCCTCA AGACTGGGAT 
CGAGTTGTGG CTGTTTTTGT ACAAGGTCCT GCTTGGCAAT TCAAAGGTTG GCCATGGCTT 
CTCCCTGATG GATCACCAGT TGACATATTT GCGAAAATTA AAGCCTTCCA TCTCAAGTAT 
GATGAAGTTC GTCTAGATCC AAATGTTCAA AAGTGGGATG TAACAGTATT AGAACTCAGC 
TATCATAAAC GTCACTTGGA TAGACCAGTT TTCTTACGTT TCTGGGAAAC ATTGGATAGA 
TACATGGTAA AGCATAAATC CCACTTGAGA TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_666103.1

Translation

MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAISVTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKYDEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF

Target ORF information:

RefSeq Version	NM_145991.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145991.1

ORF Insert Sequence:

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGAAGGTGC ATCTGCTCGT AAGACTCAAA CTCCTGCAGC CCAGCCTGTA 
CCTAGACCAG TGTCTCAAGC CAGACCCCCC CCAAATCAGA AGAAAGGGTC ACGGACACCC 
ATTATTATTA TTCCTGCAGC TACCACTTCT TTAATAACTA TGCTTAATGC AAAAGACCTT 
CTACAGGATC TGAAATTTGT CCCATCAGAT GAGAAGAAGA AACAGGGTTG TCAACGAGAA 
AATGAAACAC TAATACAGAG AAGAAAAGAC CAGATGCAAC CAGGGGGCAC AGCAATTAGT 
GTCACAGTAC CTTACAGAGT AGTAGACCAG CCCCTGAAAC TTATGCCTCA AGACTGGGAT 
CGAGTTGTGG CTGTTTTTGT ACAAGGTCCT GCTTGGCAAT TCAAAGGTTG GCCATGGCTT 
CTCCCTGATG GATCACCAGT TGACATATTT GCGAAAATTA AAGCCTTCCA TCTCAAGTAT 
GATGAAGTTC GTCTAGATCC AAATGTTCAA AAGTGGGATG TAACAGTATT AGAACTCAGC 
TATCATAAAC GTCACTTGGA TAGACCAGTT TTCTTACGTT TCTGGGAAAC ATTGGATAGA 
TACATGGTAA AGCATAAATC CCACTTGAGA TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc73 ( NM_145991.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666103.1 Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.

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CloneID	OMu17630
Clone ID Related Accession (Same CDS sequence)	NM_145991.1 , NM_145991.2
Accession Version	NM_145991.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Mus musculus(house mouse)
Product	parafibromin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL592403.6, BB645172.1, AK080861.1, AK048027.1, AK153645.1 and AK134896.1. On Sep 1, 2015 this sequence version replaced NM_145991.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031127.1, SRR1660821.194081.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGAAGGTGC ATCTGCTCGT AAGACTCAAA CTCCTGCAGC CCAGCCTGTA 
CCTAGACCAG TGTCTCAAGC CAGACCCCCC CCAAATCAGA AGAAAGGGTC ACGGACACCC 
ATTATTATTA TTCCTGCAGC TACCACTTCT TTAATAACTA TGCTTAATGC AAAAGACCTT 
CTACAGGATC TGAAATTTGT CCCATCAGAT GAGAAGAAGA AACAGGGTTG TCAACGAGAA 
AATGAAACAC TAATACAGAG AAGAAAAGAC CAGATGCAAC CAGGGGGCAC AGCAATTAGT 
GTCACAGTAC CTTACAGAGT AGTAGACCAG CCCCTGAAAC TTATGCCTCA AGACTGGGAT 
CGAGTTGTGG CTGTTTTTGT ACAAGGTCCT GCTTGGCAAT TCAAAGGTTG GCCATGGCTT 
CTCCCTGATG GATCACCAGT TGACATATTT GCGAAAATTA AAGCCTTCCA TCTCAAGTAT 
GATGAAGTTC GTCTAGATCC AAATGTTCAA AAGTGGGATG TAACAGTATT AGAACTCAGC 
TATCATAAAC GTCACTTGGA TAGACCAGTT TTCTTACGTT TCTGGGAAAC ATTGGATAGA 
TACATGGTAA AGCATAAATC CCACTTGAGA TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666103.1
CDS	270..1865
Translation	MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAISVTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKYDEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF

Target ORF information:

RefSeq Version	NM_145991.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145991.2

ORF Insert Sequence:

ATGGCGGACG TGCTCAGCGT CCTGCGACAG TACAACATCC AGAAGAAGGA GATCGTGGTC 
AAGGGGGATG AAGTGATCTT CGGGGAGTTC TCCTGGCCCA AGAATGTGAA GACCAACTAT 
GTAGTTTGGG GGACCGGAAA GGAAGGCCAA CCCAGAGAGT ACTACACATT GGATTCTATC 
TTATTTCTCC TTAATAATGT GCACCTTTCG CATCCTGTTT ATGTCCGGCG TGCAGCTACT 
GAAAATATTC CTGTGGTTAG AAGACCCGAC CGAAAAGATC TACTTGGATA TCTCAATGGG 
GAAGCATCAA CATCAGCAAG CATAGACAGG AGTGCCCCCT TGGAAATAGG TCTTCAGCGG 
TCTACTCAAG TCAAAAGAGC TGCAGATGAA GTTTTAGCAG AAGCAAAGAA ACCACGGATT 
GAGGATGAAG AGTGTGTGCG CCTTGATAAA GAGAGATTGG CAGCTCGTTT GGAAGGCCAT 
AAAGAAGGGA TCGTGCAGAC TGAGCAGATT AGGTCTTTGT CTGAAGCCAT GTCAGTGGAA 
AAAATTGCTG CAATCAAAGC CAAAATTATG GCTAAGAAAA GATCTACTAT CAAGACTGAT 
CTAGATGATG ATATAACTGC CCTTAAACAG AGGAGTTTTG TGGATGCTGA GGTAGATGTG 
ACCAGAGATA TTGTCAGCAG AGAGAGAGTG TGGAGGACAA GAACAACTAT TTTACAGAGC 
ACAGGAAAGA ATTTTTCAAA GAATATTTTT GCAATTCTTC AATCTGTAAA AGCCAGAGAA 
GAAGGTCGTG CCCCTGAACA ACGGCCAGCT CCAAATGCAG CCCCCGTGGA TCCTACATTG 
CGTACAAAAC AGCCTATTCC AGCTGCTTAC AACAGATATG ACCAAGAAAG ATTCAAAGGC 
AAAGAAGAAA CGGAAGGCTT TAAGATCGAT ACTATGGGCA CCTACCATGG CATGACACTG 
AAATCTGTAA CGGAAGGTGC ATCTGCTCGT AAGACTCAAA CTCCTGCAGC CCAGCCTGTA 
CCTAGACCAG TGTCTCAAGC CAGACCCCCC CCAAATCAGA AGAAAGGGTC ACGGACACCC 
ATTATTATTA TTCCTGCAGC TACCACTTCT TTAATAACTA TGCTTAATGC AAAAGACCTT 
CTACAGGATC TGAAATTTGT CCCATCAGAT GAGAAGAAGA AACAGGGTTG TCAACGAGAA 
AATGAAACAC TAATACAGAG AAGAAAAGAC CAGATGCAAC CAGGGGGCAC AGCAATTAGT 
GTCACAGTAC CTTACAGAGT AGTAGACCAG CCCCTGAAAC TTATGCCTCA AGACTGGGAT 
CGAGTTGTGG CTGTTTTTGT ACAAGGTCCT GCTTGGCAAT TCAAAGGTTG GCCATGGCTT 
CTCCCTGATG GATCACCAGT TGACATATTT GCGAAAATTA AAGCCTTCCA TCTCAAGTAT 
GATGAAGTTC GTCTAGATCC AAATGTTCAA AAGTGGGATG TAACAGTATT AGAACTCAGC 
TATCATAAAC GTCACTTGGA TAGACCAGTT TTCTTACGTT TCTGGGAAAC ATTGGATAGA 
TACATGGTAA AGCATAAATC CCACTTGAGA TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome.
Oncogene36(28)4025-4036(2017 Jul)
Walls GV,Stevenson M,Lines KE,Newey PJ,Reed AAC,Bowl MR,Jeyabalan J,Harding B,Bradley KJ,Manek S,Chen J,Wang P,Williams BO,Teh BT,Thakker RV

Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover.
Bone9868-78(2017 05)
Droscha CJ,Diegel CR,Ethen NJ,Burgers TA,McDonald MJ,Maupin KA,Naidu AS,Wang P,Teh BT,Williams BO

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Development (Cambridge, England)143(24)4595-4607(2016 12)
Osipovich AB,Gangula R,Vianna PG,Magnuson MA

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Nature cell biology18(11)1127-1138(2016 Nov)
Strikoudis A,Lazaris C,Trimarchi T,Galvao Neto AL,Yang Y,Ntziachristos P,Rothbart S,Buckley S,Dolgalev I,Stadtfeld M,Strahl BD,Dynlacht BD,Tsirigos A,Aifantis I

MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
Blood122(11)1914-22(2013 Sep)
Muntean AG,Chen W,Jones M,Granowicz EM,Maillard I,Hess JL

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Cdc73 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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