Srprb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Srprb
Entrez Gene ID	20818
Full Name	signal recognition particle receptor, B subunit
Synonyms	AA409543
General protein information	Preferred Names signal recognition particle receptor, B subunit Names signal recognition particle receptor subunit beta SR-beta
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_009275.4	NP_033301.1	signal recognition particle receptor subunit beta

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SRPRB	XP_003310086.1
Drosophila melanogaster (fruit fly)	SrpRbeta	NP_788485.1
Caenorhabditis elegans (roundworm)	R186.3	NP_506245.1
Arabidopsis thaliana (thale cress)	AT5G05670	NP_974735.1
Oryza sativa (rice)	Os08g0524000	NP_001062284.1
Canis lupus familiaris (dog)	SRPRB	XP_005634507.1
Mus musculus (house mouse)	Srprb	NP_033301.1
Xenopus tropicalis (tropical clawed frog)	srprb	NP_989042.2
Bos taurus (cattle)	SRPRB	XP_003585749.2
Arabidopsis thaliana (thale cress)	AT2G18770	NP_179467.1
Homo sapiens (human)	SRPRB	NP_067026.3
Gallus gallus (chicken)	LOC101750392	XP_004937051.1
Danio rerio (zebrafish)	srprb	NP_001002572.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006688	XP_316726.2
Rattus norvegicus (Norway rat)	Srprb	NP_001013270.1

Gene Ontology
Bibliography

Related articles in PubMed

Different effects of Sec61?, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.
Lang S, Benedix J, Fedeles SV, Schorr S, Schirra C, Sch?uble N, Jalal C, Greiner M, Hassdenteufel S, Tatzelt J, Kreutzer B, Edelmann L, Krause E, Rettig J, Somlo S, Zimmermann R, Dudek J
Journal of cell science125(Pt 8)1958-69(2012 Apr)

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane.
Miller JD, Tajima S, Lauffer L, Walter P
The Journal of cell biology128(3)273-82(1995 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Srprb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srprb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03849	NM_009275.4 Latest version!	Mus musculus signal recognition particle receptor, B subunit (Srprb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Srprb ( NM_009275.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033301.1 Mus musculus signal recognition particle receptor, B subunit (Srprb), mRNA.

Price & Availability↑

CloneID	OMu03849
Clone ID Related Accession (Same CDS sequence)	NM_009275.4
Accession Version	NM_009275.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	signal recognition particle receptor subunit beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK030437.1. On Apr 6, 2007 this sequence version replaced NM_009275.3. ##Evidence-Data-START## Transcript exon combination :: AK030437.1, AK167039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164137 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCGG CGAACACCCG GCGAGTTGGC GATGGCGCCG GTGGCGCCTT CCAGCCTTAC 
CTCGACTCCT TACGACAGGA GCTGCAGCAG AGGGATCCGA CGCTGCTCTC CGTGGCGGTG 
GCTCTCCTGG CGGTGCTGCT GACGCTGGTG TTCTGGAAGT TCATCTGGAG CCGAAAGAGC 
AGTCAGAGAG CTGTTCTCTT CGTTGGTCTC TGTGACTCTG GGAAAACGTT GCTGTTTGTC 
AGGTTGCTAA CTGGCCAGTA CAGAGACACA CAGACTTCCA TTACCGATAG TTCTGCCATA 
TACAAAGTCA ACAATAACAG GGGTAACAGC CTGACTCTGA TCGACCTCCC CGGGCATGAG 
AGCTTGAGGT TTCAGCTCTT AGATCGCTTT AAGTCTTCAG CTAGGGCTGT GGTGTTTGTG 
GTGGACAGTG CGGCGTTCCA GCGGGAGGTG AAAGATGTGG CCGAATTTCT GTACCAGGTC 
CTCATCGACA GCATGGCTCT GAAGAACTCA CCGTCCTTAT TAATAGCCTG CAATAAGCAA 
GATATCGCAA TGGCAAAATC AGCGAAGTTG ATCCAGCAGC AGCTTGAGAA GGAGCTCAAC 
ACCTTACGAG TCACCCGGTC CGCGGCTCCC AGCACACTGG ACAGTTCCAG CACCGCACCT 
GCTCAGTTGG GGAAGAAAGG CAAAGAATTT GAATTTTCCC AGTTGCCACT CAAAGTGGAG 
TTCCTGGAGT GTAGTGCCAA GGGTGGACGA GGGGACACTG GCTCTGCTGA CATCCAGGAC 
TTGGAGAAGT GGCTGGCCAA GATTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033301.1
CDS	7..816
Translation	MASANTRRVGDGAGGAFQPYLDSLRQELQQRDPTLLSVAVALLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRFQLLDRFKSSARAVVFVVDSAAFQREVKDVAEFLYQVLIDSMALKNSPSLLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDTGSADIQDLEKWLAKIA

Target ORF information:

RefSeq Version	NM_009275.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus signal recognition particle receptor, B subunit (Srprb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009275.4

ORF Insert Sequence:

ATGGCTTCGG CGAACACCCG GCGAGTTGGC GATGGCGCCG GTGGCGCCTT CCAGCCTTAC 
CTCGACTCCT TACGACAGGA GCTGCAGCAG AGGGATCCGA CGCTGCTCTC CGTGGCGGTG 
GCTCTCCTGG CGGTGCTGCT GACGCTGGTG TTCTGGAAGT TCATCTGGAG CCGAAAGAGC 
AGTCAGAGAG CTGTTCTCTT CGTTGGTCTC TGTGACTCTG GGAAAACGTT GCTGTTTGTC 
AGGTTGCTAA CTGGCCAGTA CAGAGACACA CAGACTTCCA TTACCGATAG TTCTGCCATA 
TACAAAGTCA ACAATAACAG GGGTAACAGC CTGACTCTGA TCGACCTCCC CGGGCATGAG 
AGCTTGAGGT TTCAGCTCTT AGATCGCTTT AAGTCTTCAG CTAGGGCTGT GGTGTTTGTG 
GTGGACAGTG CGGCGTTCCA GCGGGAGGTG AAAGATGTGG CCGAATTTCT GTACCAGGTC 
CTCATCGACA GCATGGCTCT GAAGAACTCA CCGTCCTTAT TAATAGCCTG CAATAAGCAA 
GATATCGCAA TGGCAAAATC AGCGAAGTTG ATCCAGCAGC AGCTTGAGAA GGAGCTCAAC 
ACCTTACGAG TCACCCGGTC CGCGGCTCCC AGCACACTGG ACAGTTCCAG CACCGCACCT 
GCTCAGTTGG GGAAGAAAGG CAAAGAATTT GAATTTTCCC AGTTGCCACT CAAAGTGGAG 
TTCCTGGAGT GTAGTGCCAA GGGTGGACGA GGGGACACTG GCTCTGCTGA CATCCAGGAC 
TTGGAGAAGT GGCTGGCCAA GATTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Different effects of Sec61?, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.
Journal of cell science125(Pt 8)1958-69(2012 Apr)
Lang S,Benedix J,Fedeles SV,Schorr S,Schirra C,Sch?uble N,Jalal C,Greiner M,Hassdenteufel S,Tatzelt J,Kreutzer B,Edelmann L,Krause E,Rettig J,Somlo S,Zimmermann R,Dudek J

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane.
The Journal of cell biology128(3)273-82(1995 Feb)
Miller JD,Tajima S,Lauffer L,Walter P