Sprr2a1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sprr2a1
Entrez Gene ID	20755
Full Name	small proline-rich protein 2A1
Synonyms	Sprr2a,Sprr2a3
General protein information	Preferred Names small proline-rich protein 2A1 Names small proline-rich protein 2A sprr2a3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 F1\|3 40.14 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011468.4	NP_035598.2	small proline-rich protein 2A

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sprr2a2	NP_001158259.1
Mus musculus (house mouse)	Sprr2a1	NP_035598.2

Gene Ontology
Bibliography

Related articles in PubMed

The glossopharyngeal nerve controls epithelial expression of Sprr2a and Krt13 around taste buds in the circumvallate papilla.
Miura H, Kusakabe Y, Hashido K, Hino A, Ooki M, Harada S
Neuroscience letters580147-52(2014 Sep)

Immunolocalisation and oestrogen regulation of small proline-rich protein 2a protein in the mouse uterus.
Lee HA, Kim HR, Lee YJ, Lee SJ, Kim WJ, Han SS, Yang SR, Woo HM, Na S, Song H, Hong SH
Reproduction, fertility, and development26(5)682-9(2014 Jun)

Enhanced StefinA and Sprr2 expression during papilloma formation in HPV8 transgenic mice.
Lazi? D, Alborzi F, Marcuzzi GP, Angel P, Hess J, Pfister H, Akg?l B
Journal of dermatological science62(2)84-90(2011 May)

Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern.
Lee HJ, Pazin DE, Kahlon RS, Correa SM, Albrecht KH
Developmental dynamics : an official publication of the American Association of Anatomists238(4)812-25(2009 Apr)

Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.
Demetris AJ, Specht S, Nozaki I, Lunz JG 3rd, Stolz DB, Murase N, Wu T
Journal of hepatology48(2)276-88(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sprr2a is selectively expressed in the upper layer of the epithelium surrounding taste buds in the circumvallate papilla
Title: The glossopharyngeal nerve controls epithelial expression of Sprr2a and Krt13 around taste buds in the circumvallate papilla.

Immunohistochemical staining revealed that Sprr2a protein is detected only in the adult uterus, and not in the ovary, oviduct or testis.
Title: Immunolocalisation and oestrogen regulation of small proline-rich protein 2a protein in the mouse uterus.

In non-lesional HPV8-CER transgenic skin StefinA and Sprr2 are indirect/direct transcriptional targets of HPV8
Title: Enhanced StefinA and Sprr2 expression during papilloma formation in HPV8 transgenic mice.

Small proline-rich proteins (SPRR2A) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.
Title: Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.

Data show that SPRR2a and b are allergen- and IL-13-induced in experimental allergic responses that may be involved in disease pathophysiology.
Title: Expression and regulation of small proline-rich protein 2 in allergic inflammation.

The following Sprr2a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sprr2a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10081	NM_011468.4 Latest version!	Mus musculus small proline-rich protein 2A1 (Sprr2a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sprr2a1 ( NM_011468.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035598.2 Mus musculus small proline-rich protein 2A1 (Sprr2a1), mRNA.

Price & Availability↑

CloneID	OMu10081
Clone ID Related Accession (Same CDS sequence)	NM_011468.4
Accession Version	NM_011468.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	small proline-rich protein 2A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY062071.1, AK168529.1 and AC148095.6. On Jan 27, 2006 this sequence version replaced NM_011468.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AA466367.1, AK147183.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTTACT ACCAGCAGCA GTGCAATCAG CCGTGCCGGC CTCCTCCTGT GTGCCCACCC 
CCGAAGTGCC CTGAGCCTTG TCCTCCCCAA GTGTGGCCTG GGCCTTGTCG TCCTGTCATG 
TGCTTTGAGC CTTGTCTTCC TTCAGTGTGG CCTGGGCCGT GTCGTCCTGT AGTGTGCTAT 
GAGCAATGCC CACCTCAGCC ATGGCAGTCA ACATGCCCTC CTGTGCAATT TCCACCATGC 
CAGCAGAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035598.2
CDS	148..399
Translation	MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK

Target ORF information:

RefSeq Version	NM_011468.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus small proline-rich protein 2A1 (Sprr2a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011468.4

ORF Insert Sequence:

ATGTCTTACT ACCAGCAGCA GTGCAATCAG CCGTGCCGGC CTCCTCCTGT GTGCCCACCC 
CCGAAGTGCC CTGAGCCTTG TCCTCCCCAA GTGTGGCCTG GGCCTTGTCG TCCTGTCATG 
TGCTTTGAGC CTTGTCTTCC TTCAGTGTGG CCTGGGCCGT GTCGTCCTGT AGTGTGCTAT 
GAGCAATGCC CACCTCAGCC ATGGCAGTCA ACATGCCCTC CTGTGCAATT TCCACCATGC 
CAGCAGAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The glossopharyngeal nerve controls epithelial expression of Sprr2a and Krt13 around taste buds in the circumvallate papilla.
Neuroscience letters580147-52(2014 Sep)
Miura H,Kusakabe Y,Hashido K,Hino A,Ooki M,Harada S

Immunolocalisation and oestrogen regulation of small proline-rich protein 2a protein in the mouse uterus.
Reproduction, fertility, and development26(5)682-9(2014 Jun)
Lee HA,Kim HR,Lee YJ,Lee SJ,Kim WJ,Han SS,Yang SR,Woo HM,Na S,Song H,Hong SH

Enhanced StefinA and Sprr2 expression during papilloma formation in HPV8 transgenic mice.
Journal of dermatological science62(2)84-90(2011 May)
Lazi? D,Alborzi F,Marcuzzi GP,Angel P,Hess J,Pfister H,Akg?l B

Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern.
Developmental dynamics : an official publication of the American Association of Anatomists238(4)812-25(2009 Apr)
Lee HJ,Pazin DE,Kahlon RS,Correa SM,Albrecht KH

Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.
Journal of hepatology48(2)276-88(2008 Feb)
Demetris AJ,Specht S,Nozaki I,Lunz JG 3rd,Stolz DB,Murase N,Wu T