Rfpl4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rfpl4
Entrez Gene ID	192658
Full Name	ret finger protein-like 4
Synonyms	D7Ertd486e,Rfpl4a
General protein information	Preferred Names ret finger protein-like 4 Names ret finger protein-like 4A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 A1\|7 2.96 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001145013.1	NP_001138485.1	ret finger protein-like 4A
NM_138954.3	NP_620404.1	ret finger protein-like 4A

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC750720	XP_001175000.2
Pan troglodytes (chimpanzee)	LOC737834	XP_001138383.2
Pan troglodytes (chimpanzee)	LOC738294	XP_001139061.2
Mus musculus (house mouse)	Rfpl4	NP_001138485.1
Pan troglodytes (chimpanzee)	LOC737697	XP_001137750.2
	LOC703832	XP_001092158.1
Rattus norvegicus (Norway rat)	Rfpl4a	NP_001099692.1
Pan troglodytes (chimpanzee)	LOC737755	XP_001137829.1
Pan troglodytes (chimpanzee)	LOC738180	XP_001138910.2
Pan troglodytes (chimpanzee)	LOC737517	XP_001137504.1
Pan troglodytes (chimpanzee)	LOC738131	XP_001138823.2
Pan troglodytes (chimpanzee)	LOC737994	XP_001138645.2
Pan troglodytes (chimpanzee)	LOC738025	XP_001137930.1
Canis lupus familiaris (dog)	RFPL4A	XP_541404.2
Pan troglodytes (chimpanzee)	LOC737417	XP_001137417.1
Pan troglodytes (chimpanzee)	LOC738060	XP_001138730.2
Pan troglodytes (chimpanzee)	LOC737638	XP_001137583.1

Gene Ontology
Bibliography

Related articles in PubMed

Maternal microRNAs are essential for mouse zygotic development.
Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA
Genes & development21(6)644-8(2007 Mar)

NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM
Science (New York, N.Y.)305(5687)1157-9(2004 Aug)

RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.
Suzumori N, Burns KH, Yan W, Matzuk MM
Proceedings of the National Academy of Sciences of the United States of America100(2)550-5(2003 Jan)

The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.
Rajkovic A, Lee JH, Yan C, Matzuk MM
Mechanisms of development112(1-2)173-7(2002 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RFPL4 functions as an E3 ubiquitin protein ligase to regulate protein degradation and meiosis in mouse oocytes.
Title: RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.

The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.
Title: The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.

The following Rfpl4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rfpl4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06777	NM_001145013.1 Latest version!	Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu06777	NM_138954.3 Latest version!	Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rfpl4 ( NM_001145013.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001138485.1 Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu06777
Clone ID Related Accession (Same CDS sequence)	NM_001145013.1 , NM_138954.3
Accession Version	NM_001145013.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	ret finger protein-like 4A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK139569.1, BC069834.1 and AK136022.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK136022.1, BC069834.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCATC TCTTTAAAGA GAAAAGTAAC TGTTATTTCT GCTTCCGGTG TCTGGAAAGC 
CCTGTGTACT TGAACTGTGG ATACATCTGC TGCCTCAAGT GCCTTGACTC ACTAGAGAAA 
AGTCCTGAAG GGGACGGTGT ACTGTGCCCC ACTTGCTCTG TTGTCTCTTT GAAAGAAGAC 
ATCATACATG CTAAACAGTT AGGGGCCCTG GTTACCAAGA TCAAAAACCT AGAGCCACAG 
CTGAATTTTA TTCTGACAAT GGACCAAGGT ATGAAGATAT TTCAAGTAAC CATGACCTTG 
GATGTGGACA CAGCCCAGAA CCACCTCATC ATCTCTGATG ACCTGCTGAG TGTCTACTAT 
ACGCCTCAGA AGCAAGCCCG AAAGAAATGT GCAGAAAGAT TCCATCCCTC CCCTTGTGTC 
CTGGGCTCTT CCCGGTTCAC TTCAGGCCGC CATTACTGGG AGGTAGTGGT GGGAACCAGC 
AAAGAATGGG ATATAGGCAT TTGCAAAGAG TCCATTAATC GAAAAAAGGC TATTCATTTG 
TCTGAAAAAA ATGGCTTCTG GACCGTGGGT GTGAGGGCAA AAAAGGTCTA TTCTGCCAGC 
ACTGACCCCT TGACTGTGCT GCGTGTGAAC CCTCGGCTAC GTAGAGTGGG CATTTTCCTT 
GACATGCTAG AGAAAAGTGT TTCTTTCTGG GACCTTAGCG ATGGCTCCCA TATCTATACA 
TTCCTTGAAA TTCCTGACAC GGATCCATTT CGCCCATTCT TTTCTCCAGC AAGTTCCTAT 
CCAGATGGTG ATCAAGAACA AGTCCTGAGT ATCTGTCCTG TGACAAATCC AGGCATTTTC 
GGAATTCCAG TTAACCCCCA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138485.1
CDS	52..915
Translation	MAHLFKEKSNCYFCFRCLESPVYLNCGYICCLKCLDSLEKSPEGDGVLCPTCSVVSLKEDIIHAKQLGALVTKIKNLEPQLNFILTMDQGMKIFQVTMTLDVDTAQNHLIISDDLLSVYYTPQKQARKKCAERFHPSPCVLGSSRFTSGRHYWEVVVGTSKEWDIGICKESINRKKAIHLSEKNGFWTVGVRAKKVYSASTDPLTVLRVNPRLRRVGIFLDMLEKSVSFWDLSDGSHIYTFLEIPDTDPFRPFFSPASSYPDGDQEQVLSICPVTNPGIFGIPVNPQ

Target ORF information:

RefSeq Version	NM_001145013.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145013.1

ORF Insert Sequence:

ATGGCTCATC TCTTTAAAGA GAAAAGTAAC TGTTATTTCT GCTTCCGGTG TCTGGAAAGC 
CCTGTGTACT TGAACTGTGG ATACATCTGC TGCCTCAAGT GCCTTGACTC ACTAGAGAAA 
AGTCCTGAAG GGGACGGTGT ACTGTGCCCC ACTTGCTCTG TTGTCTCTTT GAAAGAAGAC 
ATCATACATG CTAAACAGTT AGGGGCCCTG GTTACCAAGA TCAAAAACCT AGAGCCACAG 
CTGAATTTTA TTCTGACAAT GGACCAAGGT ATGAAGATAT TTCAAGTAAC CATGACCTTG 
GATGTGGACA CAGCCCAGAA CCACCTCATC ATCTCTGATG ACCTGCTGAG TGTCTACTAT 
ACGCCTCAGA AGCAAGCCCG AAAGAAATGT GCAGAAAGAT TCCATCCCTC CCCTTGTGTC 
CTGGGCTCTT CCCGGTTCAC TTCAGGCCGC CATTACTGGG AGGTAGTGGT GGGAACCAGC 
AAAGAATGGG ATATAGGCAT TTGCAAAGAG TCCATTAATC GAAAAAAGGC TATTCATTTG 
TCTGAAAAAA ATGGCTTCTG GACCGTGGGT GTGAGGGCAA AAAAGGTCTA TTCTGCCAGC 
ACTGACCCCT TGACTGTGCT GCGTGTGAAC CCTCGGCTAC GTAGAGTGGG CATTTTCCTT 
GACATGCTAG AGAAAAGTGT TTCTTTCTGG GACCTTAGCG ATGGCTCCCA TATCTATACA 
TTCCTTGAAA TTCCTGACAC GGATCCATTT CGCCCATTCT TTTCTCCAGC AAGTTCCTAT 
CCAGATGGTG ATCAAGAACA AGTCCTGAGT ATCTGTCCTG TGACAAATCC AGGCATTTTC 
GGAATTCCAG TTAACCCCCA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rfpl4 ( NM_138954.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_620404.1 Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06777
Clone ID Related Accession (Same CDS sequence)	NM_001145013.1 , NM_138954.3
Accession Version	NM_138954.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	ret finger protein-like 4A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK139569.1, AY070253.1 and AK136022.1. On Feb 4, 2009 this sequence version replaced NM_138954.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK139569.1, AY070253.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCATC TCTTTAAAGA GAAAAGTAAC TGTTATTTCT GCTTCCGGTG TCTGGAAAGC 
CCTGTGTACT TGAACTGTGG ATACATCTGC TGCCTCAAGT GCCTTGACTC ACTAGAGAAA 
AGTCCTGAAG GGGACGGTGT ACTGTGCCCC ACTTGCTCTG TTGTCTCTTT GAAAGAAGAC 
ATCATACATG CTAAACAGTT AGGGGCCCTG GTTACCAAGA TCAAAAACCT AGAGCCACAG 
CTGAATTTTA TTCTGACAAT GGACCAAGGT ATGAAGATAT TTCAAGTAAC CATGACCTTG 
GATGTGGACA CAGCCCAGAA CCACCTCATC ATCTCTGATG ACCTGCTGAG TGTCTACTAT 
ACGCCTCAGA AGCAAGCCCG AAAGAAATGT GCAGAAAGAT TCCATCCCTC CCCTTGTGTC 
CTGGGCTCTT CCCGGTTCAC TTCAGGCCGC CATTACTGGG AGGTAGTGGT GGGAACCAGC 
AAAGAATGGG ATATAGGCAT TTGCAAAGAG TCCATTAATC GAAAAAAGGC TATTCATTTG 
TCTGAAAAAA ATGGCTTCTG GACCGTGGGT GTGAGGGCAA AAAAGGTCTA TTCTGCCAGC 
ACTGACCCCT TGACTGTGCT GCGTGTGAAC CCTCGGCTAC GTAGAGTGGG CATTTTCCTT 
GACATGCTAG AGAAAAGTGT TTCTTTCTGG GACCTTAGCG ATGGCTCCCA TATCTATACA 
TTCCTTGAAA TTCCTGACAC GGATCCATTT CGCCCATTCT TTTCTCCAGC AAGTTCCTAT 
CCAGATGGTG ATCAAGAACA AGTCCTGAGT ATCTGTCCTG TGACAAATCC AGGCATTTTC 
GGAATTCCAG TTAACCCCCA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620404.1
CDS	284..1147
Translation	MAHLFKEKSNCYFCFRCLESPVYLNCGYICCLKCLDSLEKSPEGDGVLCPTCSVVSLKEDIIHAKQLGALVTKIKNLEPQLNFILTMDQGMKIFQVTMTLDVDTAQNHLIISDDLLSVYYTPQKQARKKCAERFHPSPCVLGSSRFTSGRHYWEVVVGTSKEWDIGICKESINRKKAIHLSEKNGFWTVGVRAKKVYSASTDPLTVLRVNPRLRRVGIFLDMLEKSVSFWDLSDGSHIYTFLEIPDTDPFRPFFSPASSYPDGDQEQVLSICPVTNPGIFGIPVNPQ

Target ORF information:

RefSeq Version	NM_138954.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ret finger protein-like 4 (Rfpl4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138954.3

ORF Insert Sequence:

ATGGCTCATC TCTTTAAAGA GAAAAGTAAC TGTTATTTCT GCTTCCGGTG TCTGGAAAGC 
CCTGTGTACT TGAACTGTGG ATACATCTGC TGCCTCAAGT GCCTTGACTC ACTAGAGAAA 
AGTCCTGAAG GGGACGGTGT ACTGTGCCCC ACTTGCTCTG TTGTCTCTTT GAAAGAAGAC 
ATCATACATG CTAAACAGTT AGGGGCCCTG GTTACCAAGA TCAAAAACCT AGAGCCACAG 
CTGAATTTTA TTCTGACAAT GGACCAAGGT ATGAAGATAT TTCAAGTAAC CATGACCTTG 
GATGTGGACA CAGCCCAGAA CCACCTCATC ATCTCTGATG ACCTGCTGAG TGTCTACTAT 
ACGCCTCAGA AGCAAGCCCG AAAGAAATGT GCAGAAAGAT TCCATCCCTC CCCTTGTGTC 
CTGGGCTCTT CCCGGTTCAC TTCAGGCCGC CATTACTGGG AGGTAGTGGT GGGAACCAGC 
AAAGAATGGG ATATAGGCAT TTGCAAAGAG TCCATTAATC GAAAAAAGGC TATTCATTTG 
TCTGAAAAAA ATGGCTTCTG GACCGTGGGT GTGAGGGCAA AAAAGGTCTA TTCTGCCAGC 
ACTGACCCCT TGACTGTGCT GCGTGTGAAC CCTCGGCTAC GTAGAGTGGG CATTTTCCTT 
GACATGCTAG AGAAAAGTGT TTCTTTCTGG GACCTTAGCG ATGGCTCCCA TATCTATACA 
TTCCTTGAAA TTCCTGACAC GGATCCATTT CGCCCATTCT TTTCTCCAGC AAGTTCCTAT 
CCAGATGGTG ATCAAGAACA AGTCCTGAGT ATCTGTCCTG TGACAAATCC AGGCATTTTC 
GGAATTCCAG TTAACCCCCA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Maternal microRNAs are essential for mouse zygotic development.
Genes & development21(6)644-8(2007 Mar)
Tang F,Kaneda M,O'Carroll D,Hajkova P,Barton SC,Sun YA,Lee C,Tarakhovsky A,Lao K,Surani MA

NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Science (New York, N.Y.)305(5687)1157-9(2004 Aug)
Rajkovic A,Pangas SA,Ballow D,Suzumori N,Matzuk MM

RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.
Proceedings of the National Academy of Sciences of the United States of America100(2)550-5(2003 Jan)
Suzumori N,Burns KH,Yan W,Matzuk MM

The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.
Mechanisms of development112(1-2)173-7(2002 Mar)
Rajkovic A,Lee JH,Yan C,Matzuk MM