Naip2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Naip2
Entrez Gene ID	17948
Full Name	NLR family, apoptosis inhibitory protein 2
Synonyms	Birc1b,Naip-rs6
General protein information	Preferred Names NLR family, apoptosis inhibitory protein 2 Names baculoviral IAP repeat-containing protein 1b neuronal apoptosis inhibitory protein, related sequence 6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 D1\|13 53.01 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010872.3	NP_035002.2	baculoviral IAP repeat-containing protein 1b
NM_001126182.2	NP_001119654.1	baculoviral IAP repeat-containing protein 1b

Pathways from BioSystems

Homologies

Homo sapiens (human)	NAIP	NP_004527.2
	NAIP	XP_001093532.2
Bos taurus (cattle)	NAIP	XP_002696326.1
Pan troglodytes (chimpanzee)	NAIP	XP_001156951.1
Mus musculus (house mouse)	Naip2	NP_001119654.1
Xenopus tropicalis (tropical clawed frog)	LOC100490991	XP_002934878.2

Gene Ontology
Bibliography

Related articles in PubMed

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.
Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE
The Journal of experimental medicine213(5)657-65(2016 May)

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
Zhao Y, Shi J, Shi X, Wang Y, Wang F, Shao F
The Journal of experimental medicine213(5)647-56(2016 May)

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc?.
Suzuki S, Franchi L, He Y, Mu?oz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, N??ez G
PLoS pathogens10(2)e1003926(2014 Feb)

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F
Nature477(7366)596-600(2011 Sep)

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Kofoed EM, Vance RE
Nature477(7366)592-5(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Naip1 is uniquely required to detect T3SS needle protein and Naip2 is uniquely required to detect T3SS inner rod protein, but neither Naip1 nor Naip2 is required for detection of flagellin.
Title: NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.

These results provide definitive genetic evidence for the important physiological function of NAIPs in antibacterial defense and inflammatory damage-induced lethality in mice.
Title: Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.

activation of caspase-1 by Shigella is triggered by the rod protein MxiI that interacts with Naip2 to induce activation of the Nlrc4 inflammasome independently of the Pkcdelta kinase
Title: Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc?.

The following Naip2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Naip2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu05836	NM_010872.3 Latest version!	Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
OMu05836	NM_001126182.2 Latest version!	Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Naip2 ( NM_010872.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035002.2 Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05836
Clone ID Related Accession (Same CDS sequence)	NM_010872.3 , NM_001126182.2
Accession Version	NM_010872.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	baculoviral IAP repeat-containing protein 1b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY154503.1, AY147001.1 and CT030167.8. On Sep 24, 2013 this sequence version replaced NM_010872.2. Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135489.1, AF102871.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCAGCCC AGGGAGAAGC CGTTGAGGAG ATAATTTGTG AGTTTGATGA CGACTTGGTC 
TCTGAGCTCT CTACTCTTCT CAGAGTGGAT GCACTTTCAG TCTTGAAGAG ACAACAAGAA 
GAAGACCATA AAACACGAAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACTTT TGAGACCTAT GACAAGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTTCCAC CAGACTCAGG AAACTTCCCA TAGAGAACCA CAAGAAATTA 
CGACCAGAAT GTGAGTTCCT TCTGGGCAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTTAAGA GTCCAGAGAA GATGCTGAGA GGTGACAAAG CAAGGTACCA TGAAGAGGAG 
GCAAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTCTCCTGT 
GGTGGATGCT TGGGCAACTG GGAAGAAGGA GATGATCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAGTCCCCAG AGGAAATTAC CCAATATGTA 
CAAAGCTATG AAGGATTTCT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AATGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCCG GGGCTGTTGA AGCTCTGGTC 
AAAGCAGGCC TTTTCTACAC AGGCAAAAGG GACATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGGGCAGA AGGTGACAAC CCAATAGAAG ATCACACCAA GTTTTTTCCC 
AACTGTGTGT TTCTCCAAAC CCTGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCATGA TGATGCAGCA 
GCAGTTCATT CTACAGTGGT GGATGTTTCT CCAAGTGAAG CCCAGGAACT TGAACCTGCA 
TCCAGCTTGG TGTCTGTTCT CTGTAGAGAC CAGGACCACA GTGAAGCCCA AGGGCGTGGA 
TGTGCATCCA GTGGGACCTA TCTTCCCTCC ACAGACTTGG GTCAGAGTGA AGCCCAGTGG 
CTTCAAGAGG CCAGGAGTCT GAGTGAGCAG CTGAGAGACA CCTACACCAA AGCTACTTTC 
CGCCACATGA ACTTGCCAGA AGTGTACTCC AGCCTCGGCA CTGACCATTT GCTCAGCTGC 
GATGTGTCCA TCATTTCAAA GCACATCAGC CAGCCAGTGC AAGGGTCCCT GACGATCCCT 
GAGGTCTTCT CCAATCTCAA CTCTGTCATG TGTGTGGAGG GGGAAGCTGG CAGTGGAAAG 
ACAACCTTCC TGAAGAGGAT AGCTTTTCTC TGGGCATCAG GATGCTGCCC CCTGTTGTAC 
AGGTTCCAGC TGGTCTTCTA CCTCTCCCTT AGTTCCATCA CACCAGGCCA GGAACTGGCC 
AAAATCATCT GTGCCCAACT CCTAGGGGCA GGAGGCTGCA TTAGTGAAGT GTGTCTGAGC 
AGCATCATCC AGCAGTTACA ACACCAGGTG CTGTTCCTGT TGGATGACTA CAGTGGGCTG 
GCCTCACTCC CCCAAGCCCT ACACACACTG ATTACAAAAA ACTACTTGTC ACGGACCTGC 
TTATTGATCG CTGTGCATAC AAACAAGGTC AGGGGCATCC GCCCATACCT AGATACGAGT 
CTAGAGATCA AAGAGTTTCC CTTCTATAAT ACTGTCTCTG TGTTACGGAA GCTTTTTTCA 
CATGACATAA TGCGTGTACG AAAATTTATA AATTACTTTG GATTTCATGA AGAGTTGCAG 
GGAATTCACA AGACACCCCT CTTCGTGGCA GCAGTATGTA CTGACTGGTT TAAAAATCCA 
TCTGACCAGC CCTTTCAGGA TGTGGCACTT TTCAAGGCCT ATATGCAATA CTTGTCCTTA 
AAGCACAAAG GTGCAGCTAA GCCTCTCCAG GCCACAGTGT CCTCATGTGG GCAGCTGGCC 
TTGACAGGGC TTTTCTCATC GTGCTTTGAG TTCAATAGTG ATAACCTGGC AGAGGCAGGA 
GTTGATGAAG ATGAAGAGCT CACCACCTGC TTGATGAGCA AATTCACCGC CCAGAGACTG 
AGGCCAGTCT ACCGGTTTTT AGGTCCTCTG TTCCAGGAGT TTCTTGCTGC CGTGAGGTTG 
ACTGAACTCC TGAGTTCAGA TAGGCAGGAA GACCAAGATC TGGGACTTTA TTATTTGAGA 
CAAATTAACT CACCTCTAAA GGCTATGAGC ATCTACCACA CTTTTTTGAA ATATGTCTCC 
AGCCACCCTT CATCAAAGGC AGCGCCAACA GTTGTATCTC ATTTGCTTCA GTTGGTGGAT 
GAGAAAGAGT CACTGGAGAA CATGTCTGAA AATGAGGATT ACATGAAGCT CCATCCAGAA 
GCTTTGCTGT GGATTGAGTG TCTTAGAGGA TTGTGGCAGC TGTCTCCTGA ATCTTTTTCT 
TTGTTCATTT CAGAAAACTT ATTGCGCATT TGTCTAAACT TTGCTCATGA AAGCAACACA 
GTTGCTGCAT GTTCTCCAGT TATTTTGCAG TTCCTTCGAG GGAGAACACT GGATTTGAAA 
GTTTTGAGTT TACAGTACTT TTGGGACCAT CCAGAAACCT TGTTGTTATT GAAGAGTATT 
AAGATCTCAT TAAATGGAAA TAACTGGGTA CAGAGAATCG ATTTTTCACT CATAGAAAAA 
TCTTTTGAAA AAGTACAGCC ACCAACTATA GATCAGGACT ATGCCATTGC CTTTCAACCT 
ATAAATGAAG TCCAGAAAAA TTTATCTGAA AAGAAACACA TAATAAAGAA GTATGAGGAT 
ATGAAACACC AGATCCCACT AAATATTAGT ACTGGCTACT GGAAACTGTC CCCCAAGCCA 
TACAAGATCC CCAAGCTGGA AGTTCAAGTG ACCAACACAG GTCCAGCAGA TCAAGCACTG 
CTCCAGGTCC TCATGGAAGT CTTCTCAGCT TCACAGAGTA TTGAGTTCCG TTTATCCGAC 
AGCAGTGGCT TCCTTGAAAG CATCCGCCCA GCTCTGGAGC TGAGTAAGGC CTCTGTCACC 
AAGTGTTCCA TGTCCAGGCT GGAGCTCAGC AGAGAAGATC AGAAGCTGCT TCTCACCCTG 
CCTACCCTGC AGTCTCTCGA GGTCTCAGAG ACAAACCAGT TACCAGATCA GCTCTTCCAT 
AACTTGCACA AGTTCCTGGG CCTGAAAGAA CTGTGTGTGA GACTAGATAG CAAGCCGGAT 
GTGCTCTCAG TCCTTCCTGG AGAGTTCCCA AACCTCCATC ACATGGAGAA GTTATCCATC 
AGAACCTCCA CGGAGTCTGA CCTCTCCAAA CTAGTTAAGT TGATTCAGAA CTCTCCAAAT 
CTCCATGTTT TCCATCTGAA GTGTAATTTC CTTTCGAATT GTGAGCCTCT CATGACTGTG 
CTTGCTTCCT GCAAGAAACT CAGAGAGATT GAGTTTTCTG GACGATGCTT TGAAGCCATG 
ACCTTTGTCA ACATTTTGCC AAATTTTGTT TTTCTGAAGA TATTGAATCT TAGAGACCAA 
CAATTCCCAG ATAAAGAAAC ATCAGAAAAG TTTGCCCAGG CTCTGGGTTC TCTCAGGAAC 
CTGGAGAAAC TGTTCGTTCC CACTGGGGAC GGGATTCACC AAGTGGCCAA ACTGATTGTC 
CGGCAGTGTC TGCAGCTCCC ATGTCTCCGA GTTCTTGTCT TTGCAGAGAC TCTGGATGAC 
GACAGTGTAC TGGAAATTGC CAAGGGAGCA ACCAGGGGAG GCTTCCAAAA ACTTGAGAAC 
TTAGACCTTA CACTGAATCA CAAGATTACA GAGGAAGGAT ACAGAAATTT CTTTCAAGTC 
CTGGACAACC TGCCAAACCT GAAAAACCTG GACATTTCCA GGCATATCCC AGAATGCATT 
CAAATTCAGG CCATCACTGT CAAGGCTCTG GGTCAGTGTG TGTCCCGACT GCCCAGCCTC 
ACCAGGCTCG GGATGCTCAG TTGGCTCCTG GATGAAGAGG ACATAAAAGT GATTAATGAT 
GTGAAGGAAA GACACCCTCA GTCCAAACGC TTGACTGTTC ACTGGAGGTG GGTAGTGCCA 
TTCTCTCCTG TCATTCAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035002.2
CDS	214..4557
Translation	MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKKLRPECEFLLGKDVGNIGKYDIRVKSPEKMLRGDKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGCMEKWAEGDNPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCALPEAMETTSESNHDDAAAVHSTVVDVSPSEAQELEPASSLVSVLCRDQDHSEAQGRGCASSGTYLPSTDLGQSEAQWLQEARSLSEQLRDTYTKATFRHMNLPEVYSSLGTDHLLSCDVSIISKHISQPVQGSLTIPEVFSNLNSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPGQELAKIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNKVRGIRPYLDTSLEIKEFPFYNTVSVLRKLFSHDIMRVRKFINYFGFHEELQGIHKTPLFVAAVCTDWFKNPSDQPFQDVALFKAYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDNLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQINSPLKAMSIYHTFLKYVSSHPSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPEALLWIECLRGLWQLSPESFSLFISENLLRICLNFAHESNTVAACSPVILQFLRGRTLDLKVLSLQYFWDHPETLLLLKSIKISLNGNNWVQRIDFSLIEKSFEKVQPPTIDQDYAIAFQPINEVQKNLSEKKHIIKKYEDMKHQIPLNISTGYWKLSPKPYKIPKLEVQVTNTGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSREDQKLLLTLPTLQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDSKPDVLSVLPGEFPNLHHMEKLSIRTSTESDLSKLVKLIQNSPNLHVFHLKCNFLSNCEPLMTVLASCKKLREIEFSGRCFEAMTFVNILPNFVFLKILNLRDQQFPDKETSEKFAQALGSLRNLEKLFVPTGDGIHQVAKLIVRQCLQLPCLRVLVFAETLDDDSVLEIAKGATRGGFQKLENLDLTLNHKITEEGYRNFFQVLDNLPNLKNLDISRHIPECIQIQAITVKALGQCVSRLPSLTRLGMLSWLLDEEDIKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK

Target ORF information:

RefSeq Version	NM_010872.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010872.3

ORF Insert Sequence:

ATGGCAGCCC AGGGAGAAGC CGTTGAGGAG ATAATTTGTG AGTTTGATGA CGACTTGGTC 
TCTGAGCTCT CTACTCTTCT CAGAGTGGAT GCACTTTCAG TCTTGAAGAG ACAACAAGAA 
GAAGACCATA AAACACGAAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACTTT TGAGACCTAT GACAAGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTTCCAC CAGACTCAGG AAACTTCCCA TAGAGAACCA CAAGAAATTA 
CGACCAGAAT GTGAGTTCCT TCTGGGCAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTTAAGA GTCCAGAGAA GATGCTGAGA GGTGACAAAG CAAGGTACCA TGAAGAGGAG 
GCAAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTCTCCTGT 
GGTGGATGCT TGGGCAACTG GGAAGAAGGA GATGATCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAGTCCCCAG AGGAAATTAC CCAATATGTA 
CAAAGCTATG AAGGATTTCT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AATGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCCG GGGCTGTTGA AGCTCTGGTC 
AAAGCAGGCC TTTTCTACAC AGGCAAAAGG GACATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGGGCAGA AGGTGACAAC CCAATAGAAG ATCACACCAA GTTTTTTCCC 
AACTGTGTGT TTCTCCAAAC CCTGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCATGA TGATGCAGCA 
GCAGTTCATT CTACAGTGGT GGATGTTTCT CCAAGTGAAG CCCAGGAACT TGAACCTGCA 
TCCAGCTTGG TGTCTGTTCT CTGTAGAGAC CAGGACCACA GTGAAGCCCA AGGGCGTGGA 
TGTGCATCCA GTGGGACCTA TCTTCCCTCC ACAGACTTGG GTCAGAGTGA AGCCCAGTGG 
CTTCAAGAGG CCAGGAGTCT GAGTGAGCAG CTGAGAGACA CCTACACCAA AGCTACTTTC 
CGCCACATGA ACTTGCCAGA AGTGTACTCC AGCCTCGGCA CTGACCATTT GCTCAGCTGC 
GATGTGTCCA TCATTTCAAA GCACATCAGC CAGCCAGTGC AAGGGTCCCT GACGATCCCT 
GAGGTCTTCT CCAATCTCAA CTCTGTCATG TGTGTGGAGG GGGAAGCTGG CAGTGGAAAG 
ACAACCTTCC TGAAGAGGAT AGCTTTTCTC TGGGCATCAG GATGCTGCCC CCTGTTGTAC 
AGGTTCCAGC TGGTCTTCTA CCTCTCCCTT AGTTCCATCA CACCAGGCCA GGAACTGGCC 
AAAATCATCT GTGCCCAACT CCTAGGGGCA GGAGGCTGCA TTAGTGAAGT GTGTCTGAGC 
AGCATCATCC AGCAGTTACA ACACCAGGTG CTGTTCCTGT TGGATGACTA CAGTGGGCTG 
GCCTCACTCC CCCAAGCCCT ACACACACTG ATTACAAAAA ACTACTTGTC ACGGACCTGC 
TTATTGATCG CTGTGCATAC AAACAAGGTC AGGGGCATCC GCCCATACCT AGATACGAGT 
CTAGAGATCA AAGAGTTTCC CTTCTATAAT ACTGTCTCTG TGTTACGGAA GCTTTTTTCA 
CATGACATAA TGCGTGTACG AAAATTTATA AATTACTTTG GATTTCATGA AGAGTTGCAG 
GGAATTCACA AGACACCCCT CTTCGTGGCA GCAGTATGTA CTGACTGGTT TAAAAATCCA 
TCTGACCAGC CCTTTCAGGA TGTGGCACTT TTCAAGGCCT ATATGCAATA CTTGTCCTTA 
AAGCACAAAG GTGCAGCTAA GCCTCTCCAG GCCACAGTGT CCTCATGTGG GCAGCTGGCC 
TTGACAGGGC TTTTCTCATC GTGCTTTGAG TTCAATAGTG ATAACCTGGC AGAGGCAGGA 
GTTGATGAAG ATGAAGAGCT CACCACCTGC TTGATGAGCA AATTCACCGC CCAGAGACTG 
AGGCCAGTCT ACCGGTTTTT AGGTCCTCTG TTCCAGGAGT TTCTTGCTGC CGTGAGGTTG 
ACTGAACTCC TGAGTTCAGA TAGGCAGGAA GACCAAGATC TGGGACTTTA TTATTTGAGA 
CAAATTAACT CACCTCTAAA GGCTATGAGC ATCTACCACA CTTTTTTGAA ATATGTCTCC 
AGCCACCCTT CATCAAAGGC AGCGCCAACA GTTGTATCTC ATTTGCTTCA GTTGGTGGAT 
GAGAAAGAGT CACTGGAGAA CATGTCTGAA AATGAGGATT ACATGAAGCT CCATCCAGAA 
GCTTTGCTGT GGATTGAGTG TCTTAGAGGA TTGTGGCAGC TGTCTCCTGA ATCTTTTTCT 
TTGTTCATTT CAGAAAACTT ATTGCGCATT TGTCTAAACT TTGCTCATGA AAGCAACACA 
GTTGCTGCAT GTTCTCCAGT TATTTTGCAG TTCCTTCGAG GGAGAACACT GGATTTGAAA 
GTTTTGAGTT TACAGTACTT TTGGGACCAT CCAGAAACCT TGTTGTTATT GAAGAGTATT 
AAGATCTCAT TAAATGGAAA TAACTGGGTA CAGAGAATCG ATTTTTCACT CATAGAAAAA 
TCTTTTGAAA AAGTACAGCC ACCAACTATA GATCAGGACT ATGCCATTGC CTTTCAACCT 
ATAAATGAAG TCCAGAAAAA TTTATCTGAA AAGAAACACA TAATAAAGAA GTATGAGGAT 
ATGAAACACC AGATCCCACT AAATATTAGT ACTGGCTACT GGAAACTGTC CCCCAAGCCA 
TACAAGATCC CCAAGCTGGA AGTTCAAGTG ACCAACACAG GTCCAGCAGA TCAAGCACTG 
CTCCAGGTCC TCATGGAAGT CTTCTCAGCT TCACAGAGTA TTGAGTTCCG TTTATCCGAC 
AGCAGTGGCT TCCTTGAAAG CATCCGCCCA GCTCTGGAGC TGAGTAAGGC CTCTGTCACC 
AAGTGTTCCA TGTCCAGGCT GGAGCTCAGC AGAGAAGATC AGAAGCTGCT TCTCACCCTG 
CCTACCCTGC AGTCTCTCGA GGTCTCAGAG ACAAACCAGT TACCAGATCA GCTCTTCCAT 
AACTTGCACA AGTTCCTGGG CCTGAAAGAA CTGTGTGTGA GACTAGATAG CAAGCCGGAT 
GTGCTCTCAG TCCTTCCTGG AGAGTTCCCA AACCTCCATC ACATGGAGAA GTTATCCATC 
AGAACCTCCA CGGAGTCTGA CCTCTCCAAA CTAGTTAAGT TGATTCAGAA CTCTCCAAAT 
CTCCATGTTT TCCATCTGAA GTGTAATTTC CTTTCGAATT GTGAGCCTCT CATGACTGTG 
CTTGCTTCCT GCAAGAAACT CAGAGAGATT GAGTTTTCTG GACGATGCTT TGAAGCCATG 
ACCTTTGTCA ACATTTTGCC AAATTTTGTT TTTCTGAAGA TATTGAATCT TAGAGACCAA 
CAATTCCCAG ATAAAGAAAC ATCAGAAAAG TTTGCCCAGG CTCTGGGTTC TCTCAGGAAC 
CTGGAGAAAC TGTTCGTTCC CACTGGGGAC GGGATTCACC AAGTGGCCAA ACTGATTGTC 
CGGCAGTGTC TGCAGCTCCC ATGTCTCCGA GTTCTTGTCT TTGCAGAGAC TCTGGATGAC 
GACAGTGTAC TGGAAATTGC CAAGGGAGCA ACCAGGGGAG GCTTCCAAAA ACTTGAGAAC 
TTAGACCTTA CACTGAATCA CAAGATTACA GAGGAAGGAT ACAGAAATTT CTTTCAAGTC 
CTGGACAACC TGCCAAACCT GAAAAACCTG GACATTTCCA GGCATATCCC AGAATGCATT 
CAAATTCAGG CCATCACTGT CAAGGCTCTG GGTCAGTGTG TGTCCCGACT GCCCAGCCTC 
ACCAGGCTCG GGATGCTCAG TTGGCTCCTG GATGAAGAGG ACATAAAAGT GATTAATGAT 
GTGAAGGAAA GACACCCTCA GTCCAAACGC TTGACTGTTC ACTGGAGGTG GGTAGTGCCA 
TTCTCTCCTG TCATTCAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Naip2 ( NM_001126182.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001119654.1 Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu05836
Clone ID Related Accession (Same CDS sequence)	NM_010872.3 , NM_001126182.2
Accession Version	NM_001126182.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	baculoviral IAP repeat-containing protein 1b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY154503.1, AY147001.1 and CT030167.8. On Sep 24, 2013 this sequence version replaced NM_001126182.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135490.1, AF381770.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCAGCCC AGGGAGAAGC CGTTGAGGAG ATAATTTGTG AGTTTGATGA CGACTTGGTC 
TCTGAGCTCT CTACTCTTCT CAGAGTGGAT GCACTTTCAG TCTTGAAGAG ACAACAAGAA 
GAAGACCATA AAACACGAAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACTTT TGAGACCTAT GACAAGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTTCCAC CAGACTCAGG AAACTTCCCA TAGAGAACCA CAAGAAATTA 
CGACCAGAAT GTGAGTTCCT TCTGGGCAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTTAAGA GTCCAGAGAA GATGCTGAGA GGTGACAAAG CAAGGTACCA TGAAGAGGAG 
GCAAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTCTCCTGT 
GGTGGATGCT TGGGCAACTG GGAAGAAGGA GATGATCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAGTCCCCAG AGGAAATTAC CCAATATGTA 
CAAAGCTATG AAGGATTTCT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AATGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCCG GGGCTGTTGA AGCTCTGGTC 
AAAGCAGGCC TTTTCTACAC AGGCAAAAGG GACATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGGGCAGA AGGTGACAAC CCAATAGAAG ATCACACCAA GTTTTTTCCC 
AACTGTGTGT TTCTCCAAAC CCTGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCATGA TGATGCAGCA 
GCAGTTCATT CTACAGTGGT GGATGTTTCT CCAAGTGAAG CCCAGGAACT TGAACCTGCA 
TCCAGCTTGG TGTCTGTTCT CTGTAGAGAC CAGGACCACA GTGAAGCCCA AGGGCGTGGA 
TGTGCATCCA GTGGGACCTA TCTTCCCTCC ACAGACTTGG GTCAGAGTGA AGCCCAGTGG 
CTTCAAGAGG CCAGGAGTCT GAGTGAGCAG CTGAGAGACA CCTACACCAA AGCTACTTTC 
CGCCACATGA ACTTGCCAGA AGTGTACTCC AGCCTCGGCA CTGACCATTT GCTCAGCTGC 
GATGTGTCCA TCATTTCAAA GCACATCAGC CAGCCAGTGC AAGGGTCCCT GACGATCCCT 
GAGGTCTTCT CCAATCTCAA CTCTGTCATG TGTGTGGAGG GGGAAGCTGG CAGTGGAAAG 
ACAACCTTCC TGAAGAGGAT AGCTTTTCTC TGGGCATCAG GATGCTGCCC CCTGTTGTAC 
AGGTTCCAGC TGGTCTTCTA CCTCTCCCTT AGTTCCATCA CACCAGGCCA GGAACTGGCC 
AAAATCATCT GTGCCCAACT CCTAGGGGCA GGAGGCTGCA TTAGTGAAGT GTGTCTGAGC 
AGCATCATCC AGCAGTTACA ACACCAGGTG CTGTTCCTGT TGGATGACTA CAGTGGGCTG 
GCCTCACTCC CCCAAGCCCT ACACACACTG ATTACAAAAA ACTACTTGTC ACGGACCTGC 
TTATTGATCG CTGTGCATAC AAACAAGGTC AGGGGCATCC GCCCATACCT AGATACGAGT 
CTAGAGATCA AAGAGTTTCC CTTCTATAAT ACTGTCTCTG TGTTACGGAA GCTTTTTTCA 
CATGACATAA TGCGTGTACG AAAATTTATA AATTACTTTG GATTTCATGA AGAGTTGCAG 
GGAATTCACA AGACACCCCT CTTCGTGGCA GCAGTATGTA CTGACTGGTT TAAAAATCCA 
TCTGACCAGC CCTTTCAGGA TGTGGCACTT TTCAAGGCCT ATATGCAATA CTTGTCCTTA 
AAGCACAAAG GTGCAGCTAA GCCTCTCCAG GCCACAGTGT CCTCATGTGG GCAGCTGGCC 
TTGACAGGGC TTTTCTCATC GTGCTTTGAG TTCAATAGTG ATAACCTGGC AGAGGCAGGA 
GTTGATGAAG ATGAAGAGCT CACCACCTGC TTGATGAGCA AATTCACCGC CCAGAGACTG 
AGGCCAGTCT ACCGGTTTTT AGGTCCTCTG TTCCAGGAGT TTCTTGCTGC CGTGAGGTTG 
ACTGAACTCC TGAGTTCAGA TAGGCAGGAA GACCAAGATC TGGGACTTTA TTATTTGAGA 
CAAATTAACT CACCTCTAAA GGCTATGAGC ATCTACCACA CTTTTTTGAA ATATGTCTCC 
AGCCACCCTT CATCAAAGGC AGCGCCAACA GTTGTATCTC ATTTGCTTCA GTTGGTGGAT 
GAGAAAGAGT CACTGGAGAA CATGTCTGAA AATGAGGATT ACATGAAGCT CCATCCAGAA 
GCTTTGCTGT GGATTGAGTG TCTTAGAGGA TTGTGGCAGC TGTCTCCTGA ATCTTTTTCT 
TTGTTCATTT CAGAAAACTT ATTGCGCATT TGTCTAAACT TTGCTCATGA AAGCAACACA 
GTTGCTGCAT GTTCTCCAGT TATTTTGCAG TTCCTTCGAG GGAGAACACT GGATTTGAAA 
GTTTTGAGTT TACAGTACTT TTGGGACCAT CCAGAAACCT TGTTGTTATT GAAGAGTATT 
AAGATCTCAT TAAATGGAAA TAACTGGGTA CAGAGAATCG ATTTTTCACT CATAGAAAAA 
TCTTTTGAAA AAGTACAGCC ACCAACTATA GATCAGGACT ATGCCATTGC CTTTCAACCT 
ATAAATGAAG TCCAGAAAAA TTTATCTGAA AAGAAACACA TAATAAAGAA GTATGAGGAT 
ATGAAACACC AGATCCCACT AAATATTAGT ACTGGCTACT GGAAACTGTC CCCCAAGCCA 
TACAAGATCC CCAAGCTGGA AGTTCAAGTG ACCAACACAG GTCCAGCAGA TCAAGCACTG 
CTCCAGGTCC TCATGGAAGT CTTCTCAGCT TCACAGAGTA TTGAGTTCCG TTTATCCGAC 
AGCAGTGGCT TCCTTGAAAG CATCCGCCCA GCTCTGGAGC TGAGTAAGGC CTCTGTCACC 
AAGTGTTCCA TGTCCAGGCT GGAGCTCAGC AGAGAAGATC AGAAGCTGCT TCTCACCCTG 
CCTACCCTGC AGTCTCTCGA GGTCTCAGAG ACAAACCAGT TACCAGATCA GCTCTTCCAT 
AACTTGCACA AGTTCCTGGG CCTGAAAGAA CTGTGTGTGA GACTAGATAG CAAGCCGGAT 
GTGCTCTCAG TCCTTCCTGG AGAGTTCCCA AACCTCCATC ACATGGAGAA GTTATCCATC 
AGAACCTCCA CGGAGTCTGA CCTCTCCAAA CTAGTTAAGT TGATTCAGAA CTCTCCAAAT 
CTCCATGTTT TCCATCTGAA GTGTAATTTC CTTTCGAATT GTGAGCCTCT CATGACTGTG 
CTTGCTTCCT GCAAGAAACT CAGAGAGATT GAGTTTTCTG GACGATGCTT TGAAGCCATG 
ACCTTTGTCA ACATTTTGCC AAATTTTGTT TTTCTGAAGA TATTGAATCT TAGAGACCAA 
CAATTCCCAG ATAAAGAAAC ATCAGAAAAG TTTGCCCAGG CTCTGGGTTC TCTCAGGAAC 
CTGGAGAAAC TGTTCGTTCC CACTGGGGAC GGGATTCACC AAGTGGCCAA ACTGATTGTC 
CGGCAGTGTC TGCAGCTCCC ATGTCTCCGA GTTCTTGTCT TTGCAGAGAC TCTGGATGAC 
GACAGTGTAC TGGAAATTGC CAAGGGAGCA ACCAGGGGAG GCTTCCAAAA ACTTGAGAAC 
TTAGACCTTA CACTGAATCA CAAGATTACA GAGGAAGGAT ACAGAAATTT CTTTCAAGTC 
CTGGACAACC TGCCAAACCT GAAAAACCTG GACATTTCCA GGCATATCCC AGAATGCATT 
CAAATTCAGG CCATCACTGT CAAGGCTCTG GGTCAGTGTG TGTCCCGACT GCCCAGCCTC 
ACCAGGCTCG GGATGCTCAG TTGGCTCCTG GATGAAGAGG ACATAAAAGT GATTAATGAT 
GTGAAGGAAA GACACCCTCA GTCCAAACGC TTGACTGTTC ACTGGAGGTG GGTAGTGCCA 
TTCTCTCCTG TCATTCAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119654.1
CDS	143..4486
Translation	MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKKLRPECEFLLGKDVGNIGKYDIRVKSPEKMLRGDKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGCMEKWAEGDNPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCALPEAMETTSESNHDDAAAVHSTVVDVSPSEAQELEPASSLVSVLCRDQDHSEAQGRGCASSGTYLPSTDLGQSEAQWLQEARSLSEQLRDTYTKATFRHMNLPEVYSSLGTDHLLSCDVSIISKHISQPVQGSLTIPEVFSNLNSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPGQELAKIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNKVRGIRPYLDTSLEIKEFPFYNTVSVLRKLFSHDIMRVRKFINYFGFHEELQGIHKTPLFVAAVCTDWFKNPSDQPFQDVALFKAYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDNLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQINSPLKAMSIYHTFLKYVSSHPSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPEALLWIECLRGLWQLSPESFSLFISENLLRICLNFAHESNTVAACSPVILQFLRGRTLDLKVLSLQYFWDHPETLLLLKSIKISLNGNNWVQRIDFSLIEKSFEKVQPPTIDQDYAIAFQPINEVQKNLSEKKHIIKKYEDMKHQIPLNISTGYWKLSPKPYKIPKLEVQVTNTGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSREDQKLLLTLPTLQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDSKPDVLSVLPGEFPNLHHMEKLSIRTSTESDLSKLVKLIQNSPNLHVFHLKCNFLSNCEPLMTVLASCKKLREIEFSGRCFEAMTFVNILPNFVFLKILNLRDQQFPDKETSEKFAQALGSLRNLEKLFVPTGDGIHQVAKLIVRQCLQLPCLRVLVFAETLDDDSVLEIAKGATRGGFQKLENLDLTLNHKITEEGYRNFFQVLDNLPNLKNLDISRHIPECIQIQAITVKALGQCVSRLPSLTRLGMLSWLLDEEDIKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK

Target ORF information:

RefSeq Version	NM_001126182.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126182.2

ORF Insert Sequence:

ATGGCAGCCC AGGGAGAAGC CGTTGAGGAG ATAATTTGTG AGTTTGATGA CGACTTGGTC 
TCTGAGCTCT CTACTCTTCT CAGAGTGGAT GCACTTTCAG TCTTGAAGAG ACAACAAGAA 
GAAGACCATA AAACACGAAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACTTT TGAGACCTAT GACAAGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTTCCAC CAGACTCAGG AAACTTCCCA TAGAGAACCA CAAGAAATTA 
CGACCAGAAT GTGAGTTCCT TCTGGGCAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTTAAGA GTCCAGAGAA GATGCTGAGA GGTGACAAAG CAAGGTACCA TGAAGAGGAG 
GCAAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTCTCCTGT 
GGTGGATGCT TGGGCAACTG GGAAGAAGGA GATGATCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAGTCCCCAG AGGAAATTAC CCAATATGTA 
CAAAGCTATG AAGGATTTCT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AATGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCCG GGGCTGTTGA AGCTCTGGTC 
AAAGCAGGCC TTTTCTACAC AGGCAAAAGG GACATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGGGCAGA AGGTGACAAC CCAATAGAAG ATCACACCAA GTTTTTTCCC 
AACTGTGTGT TTCTCCAAAC CCTGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCATGA TGATGCAGCA 
GCAGTTCATT CTACAGTGGT GGATGTTTCT CCAAGTGAAG CCCAGGAACT TGAACCTGCA 
TCCAGCTTGG TGTCTGTTCT CTGTAGAGAC CAGGACCACA GTGAAGCCCA AGGGCGTGGA 
TGTGCATCCA GTGGGACCTA TCTTCCCTCC ACAGACTTGG GTCAGAGTGA AGCCCAGTGG 
CTTCAAGAGG CCAGGAGTCT GAGTGAGCAG CTGAGAGACA CCTACACCAA AGCTACTTTC 
CGCCACATGA ACTTGCCAGA AGTGTACTCC AGCCTCGGCA CTGACCATTT GCTCAGCTGC 
GATGTGTCCA TCATTTCAAA GCACATCAGC CAGCCAGTGC AAGGGTCCCT GACGATCCCT 
GAGGTCTTCT CCAATCTCAA CTCTGTCATG TGTGTGGAGG GGGAAGCTGG CAGTGGAAAG 
ACAACCTTCC TGAAGAGGAT AGCTTTTCTC TGGGCATCAG GATGCTGCCC CCTGTTGTAC 
AGGTTCCAGC TGGTCTTCTA CCTCTCCCTT AGTTCCATCA CACCAGGCCA GGAACTGGCC 
AAAATCATCT GTGCCCAACT CCTAGGGGCA GGAGGCTGCA TTAGTGAAGT GTGTCTGAGC 
AGCATCATCC AGCAGTTACA ACACCAGGTG CTGTTCCTGT TGGATGACTA CAGTGGGCTG 
GCCTCACTCC CCCAAGCCCT ACACACACTG ATTACAAAAA ACTACTTGTC ACGGACCTGC 
TTATTGATCG CTGTGCATAC AAACAAGGTC AGGGGCATCC GCCCATACCT AGATACGAGT 
CTAGAGATCA AAGAGTTTCC CTTCTATAAT ACTGTCTCTG TGTTACGGAA GCTTTTTTCA 
CATGACATAA TGCGTGTACG AAAATTTATA AATTACTTTG GATTTCATGA AGAGTTGCAG 
GGAATTCACA AGACACCCCT CTTCGTGGCA GCAGTATGTA CTGACTGGTT TAAAAATCCA 
TCTGACCAGC CCTTTCAGGA TGTGGCACTT TTCAAGGCCT ATATGCAATA CTTGTCCTTA 
AAGCACAAAG GTGCAGCTAA GCCTCTCCAG GCCACAGTGT CCTCATGTGG GCAGCTGGCC 
TTGACAGGGC TTTTCTCATC GTGCTTTGAG TTCAATAGTG ATAACCTGGC AGAGGCAGGA 
GTTGATGAAG ATGAAGAGCT CACCACCTGC TTGATGAGCA AATTCACCGC CCAGAGACTG 
AGGCCAGTCT ACCGGTTTTT AGGTCCTCTG TTCCAGGAGT TTCTTGCTGC CGTGAGGTTG 
ACTGAACTCC TGAGTTCAGA TAGGCAGGAA GACCAAGATC TGGGACTTTA TTATTTGAGA 
CAAATTAACT CACCTCTAAA GGCTATGAGC ATCTACCACA CTTTTTTGAA ATATGTCTCC 
AGCCACCCTT CATCAAAGGC AGCGCCAACA GTTGTATCTC ATTTGCTTCA GTTGGTGGAT 
GAGAAAGAGT CACTGGAGAA CATGTCTGAA AATGAGGATT ACATGAAGCT CCATCCAGAA 
GCTTTGCTGT GGATTGAGTG TCTTAGAGGA TTGTGGCAGC TGTCTCCTGA ATCTTTTTCT 
TTGTTCATTT CAGAAAACTT ATTGCGCATT TGTCTAAACT TTGCTCATGA AAGCAACACA 
GTTGCTGCAT GTTCTCCAGT TATTTTGCAG TTCCTTCGAG GGAGAACACT GGATTTGAAA 
GTTTTGAGTT TACAGTACTT TTGGGACCAT CCAGAAACCT TGTTGTTATT GAAGAGTATT 
AAGATCTCAT TAAATGGAAA TAACTGGGTA CAGAGAATCG ATTTTTCACT CATAGAAAAA 
TCTTTTGAAA AAGTACAGCC ACCAACTATA GATCAGGACT ATGCCATTGC CTTTCAACCT 
ATAAATGAAG TCCAGAAAAA TTTATCTGAA AAGAAACACA TAATAAAGAA GTATGAGGAT 
ATGAAACACC AGATCCCACT AAATATTAGT ACTGGCTACT GGAAACTGTC CCCCAAGCCA 
TACAAGATCC CCAAGCTGGA AGTTCAAGTG ACCAACACAG GTCCAGCAGA TCAAGCACTG 
CTCCAGGTCC TCATGGAAGT CTTCTCAGCT TCACAGAGTA TTGAGTTCCG TTTATCCGAC 
AGCAGTGGCT TCCTTGAAAG CATCCGCCCA GCTCTGGAGC TGAGTAAGGC CTCTGTCACC 
AAGTGTTCCA TGTCCAGGCT GGAGCTCAGC AGAGAAGATC AGAAGCTGCT TCTCACCCTG 
CCTACCCTGC AGTCTCTCGA GGTCTCAGAG ACAAACCAGT TACCAGATCA GCTCTTCCAT 
AACTTGCACA AGTTCCTGGG CCTGAAAGAA CTGTGTGTGA GACTAGATAG CAAGCCGGAT 
GTGCTCTCAG TCCTTCCTGG AGAGTTCCCA AACCTCCATC ACATGGAGAA GTTATCCATC 
AGAACCTCCA CGGAGTCTGA CCTCTCCAAA CTAGTTAAGT TGATTCAGAA CTCTCCAAAT 
CTCCATGTTT TCCATCTGAA GTGTAATTTC CTTTCGAATT GTGAGCCTCT CATGACTGTG 
CTTGCTTCCT GCAAGAAACT CAGAGAGATT GAGTTTTCTG GACGATGCTT TGAAGCCATG 
ACCTTTGTCA ACATTTTGCC AAATTTTGTT TTTCTGAAGA TATTGAATCT TAGAGACCAA 
CAATTCCCAG ATAAAGAAAC ATCAGAAAAG TTTGCCCAGG CTCTGGGTTC TCTCAGGAAC 
CTGGAGAAAC TGTTCGTTCC CACTGGGGAC GGGATTCACC AAGTGGCCAA ACTGATTGTC 
CGGCAGTGTC TGCAGCTCCC ATGTCTCCGA GTTCTTGTCT TTGCAGAGAC TCTGGATGAC 
GACAGTGTAC TGGAAATTGC CAAGGGAGCA ACCAGGGGAG GCTTCCAAAA ACTTGAGAAC 
TTAGACCTTA CACTGAATCA CAAGATTACA GAGGAAGGAT ACAGAAATTT CTTTCAAGTC 
CTGGACAACC TGCCAAACCT GAAAAACCTG GACATTTCCA GGCATATCCC AGAATGCATT 
CAAATTCAGG CCATCACTGT CAAGGCTCTG GGTCAGTGTG TGTCCCGACT GCCCAGCCTC 
ACCAGGCTCG GGATGCTCAG TTGGCTCCTG GATGAAGAGG ACATAAAAGT GATTAATGAT 
GTGAAGGAAA GACACCCTCA GTCCAAACGC TTGACTGTTC ACTGGAGGTG GGTAGTGCCA 
TTCTCTCCTG TCATTCAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.
The Journal of experimental medicine213(5)657-65(2016 May)
Rauch I,Tenthorey JL,Nichols RD,Al Moussawi K,Kang JJ,Kang C,Kazmierczak BI,Vance RE

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
The Journal of experimental medicine213(5)647-56(2016 May)
Zhao Y,Shi J,Shi X,Wang Y,Wang F,Shao F

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc?.
PLoS pathogens10(2)e1003926(2014 Feb)
Suzuki S,Franchi L,He Y,Mu?oz-Planillo R,Mimuro H,Suzuki T,Sasakawa C,N??ez G

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
Nature477(7366)596-600(2011 Sep)
Zhao Y,Yang J,Shi J,Gong YN,Lu Q,Xu H,Liu L,Shao F

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Nature477(7366)592-5(2011 Aug)
Kofoed EM,Vance RE