Naip1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Naip1
Entrez Gene ID	17940
Full Name	NLR family, apoptosis inhibitory protein 1
Synonyms	AV364616,Birc1a,D13Lsd1,Naip,Naip-rs1
General protein information	Preferred Names NLR family, apoptosis inhibitory protein 1 Names baculoviral IAP repeat-containing protein 1a baculoviral IAP repeat-containing 1a neuronal apoptosis inhibitory protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 D1\|13 53.18 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008670.2	NP_032696.2	baculoviral IAP repeat-containing protein 1a

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Naip1	NP_032696.2
Mus musculus (house mouse)	Naip5	NP_035000.2
Mus musculus (house mouse)	Naip6	NP_035001.2
Rattus norvegicus (Norway rat)	Naip5	XP_006231923.1
Rattus norvegicus (Norway rat)	Naip6	XP_006231924.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.
Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E
Histochemistry and cell biology147(4)497-510(2017 Apr)

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.
Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE
The Journal of experimental medicine213(5)657-65(2016 May)

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
Zhao Y, Shi J, Shi X, Wang Y, Wang F, Shao F
The Journal of experimental medicine213(5)647-56(2016 May)

Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa.
Sellin ME, M?ller AA, Felmy B, Dolowschiak T, Diard M, Tardivel A, Maslowski KM, Hardt WD
Cell host & microbe16(2)237-248(2014 Aug)

Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.
Tenthorey JL, Kofoed EM, Daugherty MD, Malik HS, Vance RE
Molecular cell54(1)17-29(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Naip1 is uniquely required to detect T3SS needle protein and Naip2 is uniquely required to detect T3SS inner rod protein, but neither Naip1 nor Naip2 is required for detection of flagellin.
Title: NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.

These results provide definitive genetic evidence for the important physiological function of NAIPs in antibacterial defense and inflammatory damage-induced lethality in mice.
Title: Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.

An epithelium-intrinsic defense axis recruits NAIP and the NLRC4 inflammasome to promote removal of epithelial cells compromised by pathogen invasion.
Title: Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa.

NAIP/NLRC4 oligomerize, assembling inflammasomes, in the presence of their cognate bacterial ligands.
Title: Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.

In this study, the the type III secretion system needle protein protein is identified as the agonist for the orphan murine NAIP1 receptor
Title: Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein.

The following Naip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Naip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15060	NM_008670.2 Latest version!	Mus musculus NLR family, apoptosis inhibitory protein 1 (Naip1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$825.30 $1179.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Naip1 ( NM_008670.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032696.2 Mus musculus NLR family, apoptosis inhibitory protein 1 (Naip1), mRNA.

Price & Availability↑

CloneID	OMu15060
Clone ID Related Accession (Same CDS sequence)	NM_008670.2
Accession Version	NM_008670.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	baculoviral IAP repeat-containing protein 1a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF135491.1 and AF007769.1. On Sep 15, 2006 this sequence version replaced NM_008670.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135491.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGAGC ATGGGGAGTC CTCCGAGGAT CGGATTTCTG AGATTGATTA TGAATTTCTC 
CCTGAGCTCT CTGCTCTTCT CGGGGTGGAT GCAGTTCAGC TGGCAAAGAG CCAAGAAGAA 
GAAGAGCATA AAGAACGGAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACCTT TGAGACCTAT GACACGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTGGCAA TAGCCTCAGG AAGCTTCCCA TAGAGAGACA CAAGAAATTA 
CGTCCAGAAT GTGAGTTCCT TCAGGGAAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTGAAGA GTCCAGAGAA GATGCTGAGA GGTGGCAAAG CCAGGTACCA TGAAGAGGAG 
GCCAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTTTCCTGT 
GGCGGAAGCT TGGGCAACTG GGAAGAAGGA GATGACCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAATCTTCAG AGGAAATTGC CCAGTATATC 
CAAGGCTATG AGGGATTTGT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AACGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCTG TGGCTGTTGA TGCTTTGGTC 
AGAGCTGGCC TTTTCTACAC AGGCAAAAAG GGCATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGCACAGA AGGTGACGAC CCAATACAAG AGCACAACAA GTTTTTTCCC 
AACTGTGTAT TTCTCCAAAC CCCGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCACGA TGATCCAGCA 
GCAGTTCATT CTACAGTGGT GGGCTTGGGT AGGAGTGAAG CCCAGTGGTT TCAAGAGGCC 
AGGAGTCTGA GTGAGCAGCT AAGAGACAAC TACACTAAAG CCACTTTTCG CCACATGAAC 
TTGCCAGAAG TGTGCTCCAG CCTTGGCACT GACCACTTGA TCGGCTGCGA TGTGTCCATC 
ATTTCAAAGC ACATCAGCCA GCCTGTGCAA GGGGCCCTGA CGATCCCTGA GGTCTTCTCC 
AATCTCAGCT CTGTCATGTG TGTGGAGGGG GAAACTGGCA GTGGAAAGAC AACCTTCCTG 
AAGAGGATAG CTTTTCTCTG GGCATCAGGA TGCTGCCCCT TGTTGTACAG GTTCCAGCTG 
GTCTTCTACC TCTCCCTTAG TTCCATCACA CCAGACCAGG GACTGGCCAA CATCATCTGT 
GCCCAACTCC TAGGGGCAGG AGGCTGCATT AGTGAAGTGT GTCTGAGCAG CATCATCCAG 
CAGTTACAAC ACCAGGTGCT GTTCCTGTTG GATGACTACA GTGGGCTGGC CTCACTCCCC 
CAAGCCCTAC ATACACTGAT TACAAAAAAC TACTTGTCAC GGACCTGCTT ATTGATCGCT 
GTGCATACAA ACAGGGTCAG GGGCATCCGC TCATACCTAG ATACGAGTCT AGAGATCAAA 
GAGTTTCCCT TGTCCAATAC TGTCTATATA TTAAAGAAGT TCTTCTCCCA TAATATAAAA 
CGTCTACTAG AGTTTATGGT TTATTTTGGA CAGAATGAAG ATTTACAGGG AATTCACAAG 
ACCCCCCTCT TCGTGGCAGC AGTATGTACT GACTGGTTTG AAAATCCATC TGACCAGCCC 
TTTCAGGATA TGGCACTTTT CAAGTCCTAC ATGCAATACC TGTCCTTAAA GCACAAAGGT 
GCAGCTAAGC CTCTCCAAGC CACCGTGTCC TCATGTGGGC AGCTGGCCTT GACAGGGCTT 
TTCTCATCAT GCTTTGAGTT CAATAGTGAT GACCTGGCAG AGGCAGGAGT TGATGAAGAT 
GAAGAGCTCA CCACCTGCTT GATGAGCAAA TTCACCGCCC AGAGACTGAG GCCAGTCTAC 
CGGTTTTTAG GTCCGCTGTT CCAGGAGTTT CTTGCTGCCA TGAGACTGAC TGAACTTCTG 
AGTTCAGATA GGCAGGAAGA CCAAGATCTG GGACTTTATT ATTTGAGACA AATTAACTCA 
CCCTTGAAGG CTTTGACCAC CTACAACAAT TTTTTGAAGT ATGTCTTTAG CCATCCGTCA 
TCAAAGGCAG GGCCAACAGT TGTATCTCAT TTGCTTCACT TGGTGGATGA GACAGAGTTG 
CTGGAGAATA CCTATAAAAA TGAGGATTAT GTAAATCACC CTCCAGGAAC TTCCCGAATA 
ATGAAGGGAC TTAAGGAACT GTGGCTGTTA TCTCCTGAAT ATTACTCTTC ATTTGTTTCA 
GAACATTTAT TGCGCATTGC TCTAAACTTT GCTTATGAAA GCAACACTGT TGCTGAATGT 
TCTCCATTTA TTTTGCAGTT CCTTAGAGGG AGAACACTGG CTTTGAAAGT ACTGAATTTA 
CAATACTTTA GGGACCACCC AGAAAGCCTG TTACTGGTGA AGAGTTTAGA AGTCTCGATA 
AATGGAAATA AAGTGCCAAA AGTTGTAGAT TATTCAGTCA TGGAAAAAAG TTTTGAAACA 
TTACAGCCAC CAACTATAGA TCAGGACTAT GCATCCGCCT TTGAACAAAT GAAGGAACAT 
GAAAAAAATT TATCTGAAAA TGAAGAGACC ATAAAGAGTA TTAAGAACAT CTTCCCCTTA 
CAGCCACCTA AAATAAGCTC TGGCTATTGG AAACTGTCCC CCAAGCCATG CAAGATCCCT 
AGGCTGGAAG TTGGAGTGAC CAACATGGGT CCAGCAGATC AAGCACTGCT CCAGGTCCTC 
ATGGAAGTCT TCTCAGCTTC ACAGAGTATT GAGTTCCGTT TATCCGACAG CAGTGGCTTC 
CTTGAAAGCA TCCGCCCAGC TCTGGAGCTG AGTAAGGCCT CTGTCACCAA GTGTTCCATG 
TCCAGGCTGG AGCTCAGCAG AGCAGAACAG GAGCTGCTTC TCACCCTGCC TGCCCTGCAG 
TCTCTCGAGG TCTCAGAGAC AAACCAGTTA CCAGATCAGC TCTTCCATAA CTTGCACAAG 
TTCCTGGGCC TGAAAGAACT GTGTGTGAGA CTAGATGGCA AACCGGATGT GCTCTCAGTC 
CTTCCTGGAG AGTTCCCAAA CCTCCTTCAC ATGGAGAAGT TATCCATCCG AACCTCCATG 
GAGTCTGACC TCTCCAAACT AGTTAAATTG ATTCAGAACT CTCCAAATCT CCATGTTTTC 
CATCTGAAAT GTGATTTCCT TTCGAATTGT GACTCTCTCA TGGCTGTGCT TGCTTCCTGC 
AAGAAACTCA GAGAGATTGA GTTTTCTGGA CGATGCTTTG AAGCCATGCC CTTTGTTAAC 
ATTTTGCCAA ATTTTATTTC TCTGAAGATA TTAAATCTTA TAAGCCAACA ATTCCCAGAT 
AAGGAAACAT CAGAAAAGTT TGCCCAGGCT CTGGGTTCTC TCAGGAACCT GGAGGAACTG 
CTCGTTCCCA CTGGAGACGG GATTCACCAA GTGGCCAAAT TGATTGTCCG GCAGTGTCTG 
CAGCTTCCGT GTCTCCGAGT TCTTGCCTTT CACTACATCT TGGACAATGA CAGTGTGATT 
GAAATTGCCA GGGTGGCAAC CAGTGGAGGT TTCCAGAAAC TCGAGAAGTT AGATCTTTCC 
ATGAATCACA AGATTACCGA GGAAGGATAT AGAAATTTCT TTCAAGCCCT GGACAACCTG 
CCAAACTTGC AGAATCTGAA CATCTGCAGA CATATCCCAG AATGCATTCA AGTTCAGGCC 
ACCACTGTCA AGGCTCTGGG TCAATGTGTG TCCCGACTGC CCAGCCTCAC TAGGCTGCAC 
ATGCTCAGTT GGCTCCTGGA TGAAGAGGAC ATGAAAGTGA TTAATGATGT GAAGGAAAGA 
CACCCCCAGT CCAAACGCTT GATTATCTTC TGGAAATGGA TAGTCCCGTT CTCTCCTGTT 
GTCCTGGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032696.2
CDS	113..4324
Translation	MAEHGESSEDRISEIDYEFLPELSALLGVDAVQLAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKSPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFSCGGCMEKCTEGDDPIQEHNKFFPNCVFLQTPKSSAEVIPALQSHCALPEAMETTSESNHDDPAAVHSTVVGLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLIGCDVSIISKHISQPVQGALTIPEVFSNLSSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRGIRSYLDTSLEIKEFPLSNTVYILKKFFSHNIKRLLEFMVYFGQNEDLQGIHKTPLFVAAVCTDWFENPSDQPFQDMALFKSYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAMRLTELLSSDRQEDQDLGLYYLRQINSPLKALTTYNNFLKYVFSHPSSKAGPTVVSHLLHLVDETELLENTYKNEDYVNHPPGTSRIMKGLKELWLLSPEYYSSFVSEHLLRIALNFAYESNTVAECSPFILQFLRGRTLALKVLNLQYFRDHPESLLLVKSLEVSINGNKVPKVVDYSVMEKSFETLQPPTIDQDYASAFEQMKEHEKNLSENEETIKSIKNIFPLQPPKISSGYWKLSPKPCKIPRLEVGVTNMGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDGKPDVLSVLPGEFPNLLHMEKLSIRTSMESDLSKLVKLIQNSPNLHVFHLKCDFLSNCDSLMAVLASCKKLREIEFSGRCFEAMPFVNILPNFISLKILNLISQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLAFHYILDNDSVIEIARVATSGGFQKLEKLDLSMNHKITEEGYRNFFQALDNLPNLQNLNICRHIPECIQVQATTVKALGQCVSRLPSLTRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKWIVPFSPVVLE

Target ORF information:

RefSeq Version	NM_008670.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, apoptosis inhibitory protein 1 (Naip1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008670.2

ORF Insert Sequence:

ATGGCTGAGC ATGGGGAGTC CTCCGAGGAT CGGATTTCTG AGATTGATTA TGAATTTCTC 
CCTGAGCTCT CTGCTCTTCT CGGGGTGGAT GCAGTTCAGC TGGCAAAGAG CCAAGAAGAA 
GAAGAGCATA AAGAACGGAT GAAAATGAAG AAAGGTTTTA ACTCACAGAT GCGCAGTGAA 
GCCAAACGAC TAAAGACCTT TGAGACCTAT GACACGTTCA GATCATGGAC GCCACAGGAG 
ATGGCAGCTG CTGGGTTTTA CCACACAGGG GTGAAACTTG GGGTTCAGTG CTTTTGCTGT 
AGCTTGATCC TCTTTGGCAA TAGCCTCAGG AAGCTTCCCA TAGAGAGACA CAAGAAATTA 
CGTCCAGAAT GTGAGTTCCT TCAGGGAAAA GATGTTGGTA ACATTGGCAA GTATGACATC 
CGGGTGAAGA GTCCAGAGAA GATGCTGAGA GGTGGCAAAG CCAGGTACCA TGAAGAGGAG 
GCCAGACTGG AGTCCTTTGA GGACTGGCCA TTTTATGCCC ATGGGACATC ACCACGTGTA 
CTCTCAGCAG CTGGCTTTGT CTTTACAGGT AAAAGGGACA CTGTGCAGTG TTTTTCCTGT 
GGCGGAAGCT TGGGCAACTG GGAAGAAGGA GATGACCCCT GGAAGGAGCA TGCCAAGTGG 
TTCCCCAAAT GTGAATTTCT TCAAAGTAAG AAATCTTCAG AGGAAATTGC CCAGTATATC 
CAAGGCTATG AGGGATTTGT TCATGTAACG GGAGAACATT TTGTGAATTC CTGGGTCAGA 
AGAGAATTAC CTATGGTATC AGCTTACTGC AACGACAGCG TCTTCGCTAA TGAAGAACTA 
AGGATGGACA CGTTTAAGGA CTGGCCCCAC GAATCACCTG TGGCTGTTGA TGCTTTGGTC 
AGAGCTGGCC TTTTCTACAC AGGCAAAAAG GGCATTGTCC AGTGTTTTTC CTGTGGAGGA 
TGTATGGAGA AGTGCACAGA AGGTGACGAC CCAATACAAG AGCACAACAA GTTTTTTCCC 
AACTGTGTAT TTCTCCAAAC CCCGAAGTCC TCTGCAGAAG TGATTCCAGC CCTTCAGAGC 
CACTGTGCAC TTCCAGAAGC CATGGAAACC ACAAGTGAAA GCAACCACGA TGATCCAGCA 
GCAGTTCATT CTACAGTGGT GGGCTTGGGT AGGAGTGAAG CCCAGTGGTT TCAAGAGGCC 
AGGAGTCTGA GTGAGCAGCT AAGAGACAAC TACACTAAAG CCACTTTTCG CCACATGAAC 
TTGCCAGAAG TGTGCTCCAG CCTTGGCACT GACCACTTGA TCGGCTGCGA TGTGTCCATC 
ATTTCAAAGC ACATCAGCCA GCCTGTGCAA GGGGCCCTGA CGATCCCTGA GGTCTTCTCC 
AATCTCAGCT CTGTCATGTG TGTGGAGGGG GAAACTGGCA GTGGAAAGAC AACCTTCCTG 
AAGAGGATAG CTTTTCTCTG GGCATCAGGA TGCTGCCCCT TGTTGTACAG GTTCCAGCTG 
GTCTTCTACC TCTCCCTTAG TTCCATCACA CCAGACCAGG GACTGGCCAA CATCATCTGT 
GCCCAACTCC TAGGGGCAGG AGGCTGCATT AGTGAAGTGT GTCTGAGCAG CATCATCCAG 
CAGTTACAAC ACCAGGTGCT GTTCCTGTTG GATGACTACA GTGGGCTGGC CTCACTCCCC 
CAAGCCCTAC ATACACTGAT TACAAAAAAC TACTTGTCAC GGACCTGCTT ATTGATCGCT 
GTGCATACAA ACAGGGTCAG GGGCATCCGC TCATACCTAG ATACGAGTCT AGAGATCAAA 
GAGTTTCCCT TGTCCAATAC TGTCTATATA TTAAAGAAGT TCTTCTCCCA TAATATAAAA 
CGTCTACTAG AGTTTATGGT TTATTTTGGA CAGAATGAAG ATTTACAGGG AATTCACAAG 
ACCCCCCTCT TCGTGGCAGC AGTATGTACT GACTGGTTTG AAAATCCATC TGACCAGCCC 
TTTCAGGATA TGGCACTTTT CAAGTCCTAC ATGCAATACC TGTCCTTAAA GCACAAAGGT 
GCAGCTAAGC CTCTCCAAGC CACCGTGTCC TCATGTGGGC AGCTGGCCTT GACAGGGCTT 
TTCTCATCAT GCTTTGAGTT CAATAGTGAT GACCTGGCAG AGGCAGGAGT TGATGAAGAT 
GAAGAGCTCA CCACCTGCTT GATGAGCAAA TTCACCGCCC AGAGACTGAG GCCAGTCTAC 
CGGTTTTTAG GTCCGCTGTT CCAGGAGTTT CTTGCTGCCA TGAGACTGAC TGAACTTCTG 
AGTTCAGATA GGCAGGAAGA CCAAGATCTG GGACTTTATT ATTTGAGACA AATTAACTCA 
CCCTTGAAGG CTTTGACCAC CTACAACAAT TTTTTGAAGT ATGTCTTTAG CCATCCGTCA 
TCAAAGGCAG GGCCAACAGT TGTATCTCAT TTGCTTCACT TGGTGGATGA GACAGAGTTG 
CTGGAGAATA CCTATAAAAA TGAGGATTAT GTAAATCACC CTCCAGGAAC TTCCCGAATA 
ATGAAGGGAC TTAAGGAACT GTGGCTGTTA TCTCCTGAAT ATTACTCTTC ATTTGTTTCA 
GAACATTTAT TGCGCATTGC TCTAAACTTT GCTTATGAAA GCAACACTGT TGCTGAATGT 
TCTCCATTTA TTTTGCAGTT CCTTAGAGGG AGAACACTGG CTTTGAAAGT ACTGAATTTA 
CAATACTTTA GGGACCACCC AGAAAGCCTG TTACTGGTGA AGAGTTTAGA AGTCTCGATA 
AATGGAAATA AAGTGCCAAA AGTTGTAGAT TATTCAGTCA TGGAAAAAAG TTTTGAAACA 
TTACAGCCAC CAACTATAGA TCAGGACTAT GCATCCGCCT TTGAACAAAT GAAGGAACAT 
GAAAAAAATT TATCTGAAAA TGAAGAGACC ATAAAGAGTA TTAAGAACAT CTTCCCCTTA 
CAGCCACCTA AAATAAGCTC TGGCTATTGG AAACTGTCCC CCAAGCCATG CAAGATCCCT 
AGGCTGGAAG TTGGAGTGAC CAACATGGGT CCAGCAGATC AAGCACTGCT CCAGGTCCTC 
ATGGAAGTCT TCTCAGCTTC ACAGAGTATT GAGTTCCGTT TATCCGACAG CAGTGGCTTC 
CTTGAAAGCA TCCGCCCAGC TCTGGAGCTG AGTAAGGCCT CTGTCACCAA GTGTTCCATG 
TCCAGGCTGG AGCTCAGCAG AGCAGAACAG GAGCTGCTTC TCACCCTGCC TGCCCTGCAG 
TCTCTCGAGG TCTCAGAGAC AAACCAGTTA CCAGATCAGC TCTTCCATAA CTTGCACAAG 
TTCCTGGGCC TGAAAGAACT GTGTGTGAGA CTAGATGGCA AACCGGATGT GCTCTCAGTC 
CTTCCTGGAG AGTTCCCAAA CCTCCTTCAC ATGGAGAAGT TATCCATCCG AACCTCCATG 
GAGTCTGACC TCTCCAAACT AGTTAAATTG ATTCAGAACT CTCCAAATCT CCATGTTTTC 
CATCTGAAAT GTGATTTCCT TTCGAATTGT GACTCTCTCA TGGCTGTGCT TGCTTCCTGC 
AAGAAACTCA GAGAGATTGA GTTTTCTGGA CGATGCTTTG AAGCCATGCC CTTTGTTAAC 
ATTTTGCCAA ATTTTATTTC TCTGAAGATA TTAAATCTTA TAAGCCAACA ATTCCCAGAT 
AAGGAAACAT CAGAAAAGTT TGCCCAGGCT CTGGGTTCTC TCAGGAACCT GGAGGAACTG 
CTCGTTCCCA CTGGAGACGG GATTCACCAA GTGGCCAAAT TGATTGTCCG GCAGTGTCTG 
CAGCTTCCGT GTCTCCGAGT TCTTGCCTTT CACTACATCT TGGACAATGA CAGTGTGATT 
GAAATTGCCA GGGTGGCAAC CAGTGGAGGT TTCCAGAAAC TCGAGAAGTT AGATCTTTCC 
ATGAATCACA AGATTACCGA GGAAGGATAT AGAAATTTCT TTCAAGCCCT GGACAACCTG 
CCAAACTTGC AGAATCTGAA CATCTGCAGA CATATCCCAG AATGCATTCA AGTTCAGGCC 
ACCACTGTCA AGGCTCTGGG TCAATGTGTG TCCCGACTGC CCAGCCTCAC TAGGCTGCAC 
ATGCTCAGTT GGCTCCTGGA TGAAGAGGAC ATGAAAGTGA TTAATGATGT GAAGGAAAGA 
CACCCCCAGT CCAAACGCTT GATTATCTTC TGGAAATGGA TAGTCCCGTT CTCTCCTGTT 
GTCCTGGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.
Histochemistry and cell biology147(4)497-510(2017 Apr)
Svandova EB,Vesela B,Lesot H,Poliard A,Matalova E

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.
The Journal of experimental medicine213(5)657-65(2016 May)
Rauch I,Tenthorey JL,Nichols RD,Al Moussawi K,Kang JJ,Kang C,Kazmierczak BI,Vance RE

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
The Journal of experimental medicine213(5)647-56(2016 May)
Zhao Y,Shi J,Shi X,Wang Y,Wang F,Shao F

Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa.
Cell host & microbe16(2)237-248(2014 Aug)
Sellin ME,M?ller AA,Felmy B,Dolowschiak T,Diard M,Tardivel A,Maslowski KM,Hardt WD

Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.
Molecular cell54(1)17-29(2014 Apr)
Tenthorey JL,Kofoed EM,Daugherty MD,Malik HS,Vance RE