Il11ra1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il11ra1
Entrez Gene ID	16157
Full Name	interleukin 11 receptor, alpha chain 1
Synonyms	AI314697,GP130,Il-11ra,Il11ra,Il11ra2,NR1
General protein information	Preferred Names interleukin 11 receptor, alpha chain 1 Names interleukin-11 receptor subunit alpha-1 IL-11 receptor subunit alpha-1 IL-11R subunit alpha-1 IL-11R-alpha-1 IL-11RA1 Il-11ra-alpha NR-1 enhancer trap locus homolog 2 etl-2 interleukin 11 receptor, alpha chain 2 locus 2 novel cytokine receptor 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 A5\|4 21.94 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010549.3	NP_034679.1	interleukin-11 receptor subunit alpha-1 precursor
NM_001163401.1	NP_001156873.1	interleukin-11 receptor subunit alpha-1 precursor
NM_001172054.1	NP_001165525.1	interleukin-11 receptor subunit alpha-1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IL11RA	XP_005626799.1
Mus musculus (house mouse)	Il11ra1	NP_034679.1
Mus musculus (house mouse)	Gm13305	NP_001092818.1
Mus musculus (house mouse)	Il11ra2	NP_034680.3
Gallus gallus (chicken)	IL11RA	NP_001038139.1
	IL11RA	XP_001093448.2
Xenopus tropicalis (tropical clawed frog)	il11ra	NP_001093752.1
Homo sapiens (human)	IL11RA	NP_001136256.1
Pan troglodytes (chimpanzee)	IL11RA	NP_001238787.1
Bos taurus (cattle)	IL11RA	NP_001029511.1
Rattus norvegicus (Norway rat)	Il11ra1	NP_620816.1
Mus musculus (house mouse)	LOC100861969	XP_006542822.1
Mus musculus (house mouse)	Gm2002	NP_001094066.1
Danio rerio (zebrafish)	il11ra	NP_001106971.1

Gene Ontology
Bibliography

Related articles in PubMed

IL-11 is a crucial determinant of cardiovascular fibrosis.
Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimar?es-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA
Nature552(7683)110-115(2017 Dec)

Interleukin-11 classic but not trans-signaling is essential for fertility in mice.
Agthe M, Garbers Y, Putoczki T, Garbers C
Placenta5713-16(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.
Title: Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.

In spite of clear changes in the temporal expression of both IL-11 and its receptor, no significant differences in motor function are found after spinal cord injury.
Title: Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury.

Signaling through the IL-35 receptor required the transcription factors STAT1 and STAT4.
Title: The composition and signaling of the IL-35 receptor are unconventional.

Demyelination and oligodendrocyte death are exacerbated in IL-11 receptor alpha-deficient mice, suggesting avenues to enhance oligodendrocyte viability and restrict central nervous system inflammation in multiple sclerosis.
Title: Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11.

These results provide, at least in part, an explanation for the defective small decidua of mice lacking the Il11ra gene, and reveal for the first time that cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) are targets of IL11 in the decidua.
Title: Involvement of cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in interleukin 11 stimulation of decidualization in mice.

The following Il11ra1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il11ra1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06340	NM_010549.3 Latest version!	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu06340	NM_001172054.1 Latest version!	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu06340	NM_001163401.1 Latest version!	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il11ra1 ( NM_010549.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034679.1 Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06340
Clone ID Related Accession (Same CDS sequence)	NM_010549.3 , NM_001163401.1 , NM_001172054.1
Accession Version	NM_010549.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	interleukin-11 receptor subunit alpha-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY149476.1, AK159559.1 and AK146742.1. On Jul 18, 2009 this sequence version replaced NM_010549.2. Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, compared to variant 3. Variants 1-3 all encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X74953.1, BC057664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034679.1
CDS	115..1413
Translation	MSSSCSGLTRVLVAVATALVSSSSPCPQAWGPPGVQYGQPGRPVMLCCPGVSAGTPVSWFRDGDSRLLQGPDSGLGHRLVLAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPEVSCQAVDYENFSCTWSPGQVSGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTCLLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEEVITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWGTPSTGPLQDEIPDWSQGHGQQLEAVVAQEDSPAPARPSLQPDPRPLDHRDPLEQVAVLASLGIFSCLGLAVGALALGLWLRLRRSGKDGPQKPGLLAPMIPVEKLPGIPNLQRTPENFS

Target ORF information:

RefSeq Version	NM_010549.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010549.3

ORF Insert Sequence:

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il11ra1 ( NM_001163401.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001156873.1 Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu06340
Clone ID Related Accession (Same CDS sequence)	NM_010549.3 , NM_001163401.1 , NM_001172054.1
Accession Version	NM_001163401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	interleukin-11 receptor subunit alpha-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY777524.1, AK159559.1 and AK146742.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 1-3 all encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK146742.1, AK159559.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156873.1
CDS	110..1408
Translation	MSSSCSGLTRVLVAVATALVSSSSPCPQAWGPPGVQYGQPGRPVMLCCPGVSAGTPVSWFRDGDSRLLQGPDSGLGHRLVLAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPEVSCQAVDYENFSCTWSPGQVSGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTCLLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEEVITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWGTPSTGPLQDEIPDWSQGHGQQLEAVVAQEDSPAPARPSLQPDPRPLDHRDPLEQVAVLASLGIFSCLGLAVGALALGLWLRLRRSGKDGPQKPGLLAPMIPVEKLPGIPNLQRTPENFS

Target ORF information:

RefSeq Version	NM_001163401.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163401.1

ORF Insert Sequence:

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il11ra1 ( NM_001172054.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001165525.1 Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu06340
Clone ID Related Accession (Same CDS sequence)	NM_010549.3 , NM_001163401.1 , NM_001172054.1
Accession Version	NM_001172054.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	interleukin-11 receptor subunit alpha-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807796.17. Transcript Variant: This variant (3) represents the longest transcript. Variants 1-3 all encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069984.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165525.1
CDS	196..1494
Translation	MSSSCSGLTRVLVAVATALVSSSSPCPQAWGPPGVQYGQPGRPVMLCCPGVSAGTPVSWFRDGDSRLLQGPDSGLGHRLVLAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPEVSCQAVDYENFSCTWSPGQVSGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTCLLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEEVITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWGTPSTGPLQDEIPDWSQGHGQQLEAVVAQEDSPAPARPSLQPDPRPLDHRDPLEQVAVLASLGIFSCLGLAVGALALGLWLRLRRSGKDGPQKPGLLAPMIPVEKLPGIPNLQRTPENFS

Target ORF information:

RefSeq Version	NM_001172054.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 11 receptor, alpha chain 1 (Il11ra1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172054.1

ORF Insert Sequence:

ATGAGCAGCA GCTGCTCAGG GCTGACCAGG GTCCTGGTGG CCGTGGCTAC AGCCCTGGTG 
TCTTCCTCCT CCCCCTGCCC CCAAGCTTGG GGTCCTCCAG GGGTCCAGTA TGGACAACCT 
GGCAGGCCCG TGATGCTGTG CTGCCCCGGA GTGAGTGCTG GGACTCCAGT GTCCTGGTTT 
CGGGATGGAG ATTCAAGGCT GCTCCAGGGA CCTGACTCTG GGTTAGGACA CAGACTGGTC 
TTGGCCCAGG TGGACAGCCC TGATGAAGGC ACTTATGTCT GCCAGACCCT GGATGGTGTA 
TCAGGGGGCA TGGTGACCCT GAAGCTGGGC TTTCCCCCAG CACGTCCTGA AGTCTCCTGC 
CAAGCGGTAG ACTATGAAAA CTTCTCCTGT ACTTGGAGTC CAGGCCAGGT CAGCGGTTTG 
CCCACCCGCT ACCTTACTTC CTACAGGAAG AAGACGCTGC CAGGAGCTGA GAGTCAGAGG 
GAAAGTCCAT CCACCGGGCC TTGGCCGTGT CCACAGGACC CTCTGGAGGC CTCCCGATGT 
GTGGTCCATG GGGCAGAGTT CTGGAGTGAG TACCGGATCA ATGTGACCGA GGTGAACCCA 
CTGGGTGCCA GCACGTGCCT ACTGGATGTG AGATTACAGA GCATCTTGCG TCCTGATCCA 
CCCCAAGGAC TGCGGGTGGA ATCCGTACCT GGTTACCCGA GACGCCTGCA TGCCAGCTGG 
ACATACCCTG CCTCCTGGCG TCGCCAACCC CACTTTCTGC TCAAGTTCCG GTTGCAATAC 
CGACCAGCAC AGCATCCAGC CTGGTCCACG GTGGAGCCCA TTGGCTTGGA GGAAGTGATA 
ACAGATGCTG TGGCTGGGCT GCCACACGCG GTACGAGTCA GTGCCAGGGA CTTTCTGGAT 
GCTGGCACCT GGAGCGCCTG GAGCCCAGAG GCCTGGGGTA CTCCTAGCAC TGGTCCCCTG 
CAGGATGAGA TACCTGATTG GAGCCAGGGA CACGGACAGC AGCTAGAGGC AGTAGTAGCT 
CAGGAGGACA GCCCGGCTCC TGCAAGGCCT TCCTTGCAGC CGGACCCAAG GCCACTTGAT 
CACAGGGACC CCTTGGAGCA AGTAGCTGTG TTAGCGTCTC TGGGAATCTT CTCTTGCCTT 
GGCCTGGCTG TTGGAGCTCT GGCACTGGGG CTCTGGCTGA GGCTGAGACG GAGTGGGAAG 
GATGGACCGC AAAAACCTGG GCTCTTGGCA CCCATGATCC CGGTGGAAAA GCTTCCAGGA 
ATTCCAAACC TGCAGAGGAC CCCAGAGAAC TTCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IL-11 is a crucial determinant of cardiovascular fibrosis.
Nature552(7683)110-115(2017 Dec)
Schafer S,Viswanathan S,Widjaja AA,Lim WW,Moreno-Moral A,DeLaughter DM,Ng B,Patone G,Chow K,Khin E,Tan J,Chothani SP,Ye L,Rackham OJL,Ko NSJ,Sahib NE,Pua CJ,Zhen NTG,Xie C,Wang M,Maatz H,Lim S,Saar K,Blachut S,Petretto E,Schmidt S,Putoczki T,Guimar?es-Camboa N,Wakimoto H,van Heesch S,Sigmundsson K,Lim SL,Soon JL,Chao VTT,Chua YL,Tan TE,Evans SM,Loh YJ,Jamal MH,Ong KK,Chua KC,Ong BH,Chakaramakkil MJ,Seidman JG,Seidman CE,Hubner N,Sin KYK,Cook SA

Interleukin-11 classic but not trans-signaling is essential for fertility in mice.
Placenta5713-16(2017 Sep)
Agthe M,Garbers Y,Putoczki T,Garbers C

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Il11ra1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム