Hao1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hao1
Entrez Gene ID	15112
Full Name	hydroxyacid oxidase 1, liver
Synonyms	GOX,Gox1,Hao-1
General protein information	Preferred Names hydroxyacid oxidase 1, liver Names hydroxyacid oxidase 1 HAOX1 glycolate oxidase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 F2\|2 65.65 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010403.2	NP_034533.1	hydroxyacid oxidase 1

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os03g0786100	NP_001051487.1
Homo sapiens (human)	HAO1	NP_060015.1
	HAO1	XP_001116000.1
Danio rerio (zebrafish)	hao1	NP_001077011.1
Arabidopsis thaliana (thale cress)	AT3G14420	NP_850584.1
Oryza sativa (rice)	Os07g0152900	NP_001058909.1
Pan troglodytes (chimpanzee)	HAO1	XP_001167611.1
Mus musculus (house mouse)	Hao1	NP_034533.1
Rattus norvegicus (Norway rat)	Hao1	NP_001101250.1
Arabidopsis thaliana (thale cress)	AT4G18360	NP_193570.1
Drosophila melanogaster (fruit fly)	CG18003	NP_001027402.1
Canis lupus familiaris (dog)	HAO1	XP_542897.2
Gallus gallus (chicken)	HAO1	NP_001186371.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010885	XP_309809.3
Caenorhabditis elegans (roundworm)	F41E6.5	NP_001122941.1
Arabidopsis thaliana (thale cress)	AT3G14415	NP_001189891.1

Gene Ontology
Bibliography

Related articles in PubMed

Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Li X, Knight J, Fargue S, Buchalski B, Guan Z, Inscho EW, Liebow A, Fitzgerald K, Querbes W, Todd Lowther W, Holmes RP
Biochimica et biophysica acta1862(2)233-9(2016 Feb)

The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation.
Labialle S, Marty V, Bortolin-Cavaill? ML, Hoareau-Osman M, Prad?re JP, Valet P, Martin PG, Cavaill? J
The EMBO journal33(19)2216-30(2014 Oct)

Incorporation of beta-sitosterol into the membrane increases resistance to oxidative stress and lipid peroxidation via estrogen receptor-mediated PI3K/GSK3beta signaling.
Shi C, Wu F, Zhu XC, Xu J
Biochimica et biophysica acta1830(3)2538-44(2013 Mar)

Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.
Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T, Taniguchi H
The Journal of biological chemistry279(1)421-8(2004 Jan)

Identification and expression of a cDNA for human glycolate oxidase.
Williams E, Cregeen D, Rumsby G
Biochimica et biophysica acta1493(1-2)246-8(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hao1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hao1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15936	NM_010403.2 Latest version!	Mus musculus hydroxyacid oxidase 1, liver (Hao1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hao1 ( NM_010403.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034533.1 Mus musculus hydroxyacid oxidase 1, liver (Hao1), mRNA.

Price & Availability↑

CloneID	OMu15936
Clone ID Related Accession (Same CDS sequence)	NM_010403.2
Accession Version	NM_010403.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	hydroxyacid oxidase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL845309.2. On Mar 21, 2007 this sequence version replaced NM_010403.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF104312.1, AK149565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGTTGCCTC GACTGGTCTG CATCAGTGAT TATGAACAGC ATGTCCGATC AGTGCTTCAG 
AAGTCAGTGT ATGACTATTA CAGGTCTGGG GCAAATGATC AGGAGACGTT AGCTGATAAC 
ATCCAAGCAT TTTCTAGATG GAAGCTCTAT CCACGGATGC TTCGCAACGT TGCTGATATC 
GATCTGTCAA CTTCTGTTTT AGGACAGAGA GTCAGCATGC CAATATGTGT TGGGGCTACT 
GCCATGCAGT GCATGGCTCA CGTGGACGGG GAGCTGGCCA CTGTGCGAGC CTGTCAGACC 
ATGGGAACTG GCATGATGCT GAGTTCTTGG GCTACCTCCT CAATAGAAGA AGTGGCAGAA 
GCTGGCCCAG AGGCACTTCG CTGGATGCAA CTGTACATCT ACAAAGACCG TGAGATCAGC 
AGACAGATAG TGAAGCGAGC TGAGAAGCAG GGTTACAAGG CCATATTTGT GACTGTGGAC 
ACCCCTTACC TGGGCAACCG CATTGATGAC GTGCGGAACA GGTTCAAGCT GCCACCACAA 
CTCAGGATGA AAAACTTTGA AACCAATGAT TTGGCATTTT CTCCTAAGGG AAATTTTGGA 
GACAACAGTG GACTTGCTGA ATATGTGGCA CAAGCTATAG ACCCATCTCT CAGCTGGGAT 
GATATTACAT GGCTCAGACG ATTGACATCA CTGCCTATTG TTGTAAAGGG CATTTTGAGA 
GGTGATGATG CCAAGGAAGC TGTTAAACAT GGTGTGGATG GGATCTTGGT GTCGAATCAT 
GGGGCGCGAC AACTGGATGG GGTGCCAGCT ACTATTGATG TCCTGCCAGA GATTGTTGAG 
GCTGTGGAAG GGAAGGTAGA AGTCTTCCTG GATGGGGGAG TAAGGAAAGG TACTGATGTT 
CTCAAAGCTC TGGCCCTAGG AGCCAAGGCC GTTTTTGTGG GAAGACCCAT CATCTGGGGC 
TTGGCTTTCC AGGGGGAGAA AGGTGTTCAA GATGTCCTCG AGATATTGAA GGAAGAATTC 
CGACTGGCCA TGGCTCTGAG TGGGTGCCAG AATGTGAAAG TCATCGACAA GACATTGGTG 
AGGAAAAATC CTTTGGCTGT TTCCAAGATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034533.1
CDS	21..1133
Translation	MLPRLVCISDYEQHVRSVLQKSVYDYYRSGANDQETLADNIQAFSRWKLYPRMLRNVADIDLSTSVLGQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALRWMQLYIYKDREISRQIVKRAEKQGYKAIFVTVDTPYLGNRIDDVRNRFKLPPQLRMKNFETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDITWLRRLTSLPIVVKGILRGDDAKEAVKHGVDGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI

Target ORF information:

RefSeq Version	NM_010403.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus hydroxyacid oxidase 1, liver (Hao1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010403.2

ORF Insert Sequence:

ATGTTGCCTC GACTGGTCTG CATCAGTGAT TATGAACAGC ATGTCCGATC AGTGCTTCAG 
AAGTCAGTGT ATGACTATTA CAGGTCTGGG GCAAATGATC AGGAGACGTT AGCTGATAAC 
ATCCAAGCAT TTTCTAGATG GAAGCTCTAT CCACGGATGC TTCGCAACGT TGCTGATATC 
GATCTGTCAA CTTCTGTTTT AGGACAGAGA GTCAGCATGC CAATATGTGT TGGGGCTACT 
GCCATGCAGT GCATGGCTCA CGTGGACGGG GAGCTGGCCA CTGTGCGAGC CTGTCAGACC 
ATGGGAACTG GCATGATGCT GAGTTCTTGG GCTACCTCCT CAATAGAAGA AGTGGCAGAA 
GCTGGCCCAG AGGCACTTCG CTGGATGCAA CTGTACATCT ACAAAGACCG TGAGATCAGC 
AGACAGATAG TGAAGCGAGC TGAGAAGCAG GGTTACAAGG CCATATTTGT GACTGTGGAC 
ACCCCTTACC TGGGCAACCG CATTGATGAC GTGCGGAACA GGTTCAAGCT GCCACCACAA 
CTCAGGATGA AAAACTTTGA AACCAATGAT TTGGCATTTT CTCCTAAGGG AAATTTTGGA 
GACAACAGTG GACTTGCTGA ATATGTGGCA CAAGCTATAG ACCCATCTCT CAGCTGGGAT 
GATATTACAT GGCTCAGACG ATTGACATCA CTGCCTATTG TTGTAAAGGG CATTTTGAGA 
GGTGATGATG CCAAGGAAGC TGTTAAACAT GGTGTGGATG GGATCTTGGT GTCGAATCAT 
GGGGCGCGAC AACTGGATGG GGTGCCAGCT ACTATTGATG TCCTGCCAGA GATTGTTGAG 
GCTGTGGAAG GGAAGGTAGA AGTCTTCCTG GATGGGGGAG TAAGGAAAGG TACTGATGTT 
CTCAAAGCTC TGGCCCTAGG AGCCAAGGCC GTTTTTGTGG GAAGACCCAT CATCTGGGGC 
TTGGCTTTCC AGGGGGAGAA AGGTGTTCAA GATGTCCTCG AGATATTGAA GGAAGAATTC 
CGACTGGCCA TGGCTCTGAG TGGGTGCCAG AATGTGAAAG TCATCGACAA GACATTGGTG 
AGGAAAAATC CTTTGGCTGT TTCCAAGATC TGA