Eif4g2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif4g2
Entrez Gene ID	13690
Full Name	eukaryotic translation initiation factor 4, gamma 2
Synonyms	DAP-5,E130105L11Rik,Nat1,Natm1,p97
General protein information	Preferred Names eukaryotic translation initiation factor 4, gamma 2 Names eukaryotic translation initiation factor 4 gamma 2 eIF-4-gamma 2 eIF-4G 2 eIF4G 2 eif4g2 novel APOBEC-1 target 1 translation repressor Nat1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 E3\|7 58.0 cM
Summary	Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G, that contains the binding sites for eIF4A and eIF3; eIF4G in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. Transgene expression of the apolipoprotein B mRNA-editing enzyme (APOBEC-1) causes extensive editing of this mRNA, which could contribute to the potent oncogenesis induced by overexpression of APOBEC-1. In vitro and in vivo studies in human indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. This also appears to be true for mouse. Two alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040131.2	NP_001035221.1	eukaryotic translation initiation factor 4 gamma 2 isoform 2
NM_013507.3	NP_038535.2	eukaryotic translation initiation factor 4 gamma 2 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	EIF4G2	XP_003951884.1
	EIF4G2	XP_001093873.2
Mus musculus (house mouse)	Eif4g2	NP_038535.2
Homo sapiens (human)	EIF4G2	NP_001409.3
Gallus gallus (chicken)	EIF4G2	NP_001093330.1
Xenopus tropicalis (tropical clawed frog)	eif4g2	NP_001004992.1
Bos taurus (cattle)	EIF4G2	NP_001093329.1
Rattus norvegicus (Norway rat)	Eif4g2	NP_001017374.2
Canis lupus familiaris (dog)	EIF4G2	XP_005633865.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Thyroid hormone increases bulk histones expression by enhancing translational efficiency.
Zambrano A, Garc?a-Carpizo V, Villamuera R, Aranda A
Molecular endocrinology (Baltimore, Md.)29(1)68-75(2015 Jan)

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Distler U, Schmeisser MJ, Pelosi A, Reim D, Kuharev J, Weiczner R, Baumgart J, Boeckers TM, Nitsch R, Vogt J, Tenzer S
Proteomics14(21-22)2607-13(2014 Nov)

Blastocyst implantation failure relates to impaired translational machinery gene expression.
Plaks V, Gershon E, Zeisel A, Jacob-Hirsch J, Neeman M, Winterhager E, Rechavi G, Domany E, Dekel N
Reproduction (Cambridge, England)148(1)87-98(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G
Title: Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.

in vitro and in vivo studies in human show that translation starts at a non-AUG (GUG) codon. Suggest the same in mouse based on sequence conservation.
Title: A new translational regulator with homology to eukaryotic translation initiation factor 4G.

translation starts at a non-AUG translation initiation codon (GUG).
Title: cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G.

The following Eif4g2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif4g2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14819	NM_001040131.2 Latest version!	Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu15166	NM_013507.3 Latest version!	Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif4g2 ( NM_001040131.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035221.1 Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu14819
Clone ID Related Accession (Same CDS sequence)	NM_001040131.2
Accession Version	NM_001040131.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2607bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 4 gamma 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI874618.1, BC043034.1, AC150312.2 and AC159206.2. On Jul 25, 2007 this sequence version replaced NM_001040131.1. Transcript Variant: This variant (2) lacks an alternate in-frame segment, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC057673.1, BC039274.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 9027506, 9049310 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

GTGGAGAGTG CGATTGCAGA AGGGGGTGCT TCTCGTTTCA GTGCTTCTTC GGGCGGAGGA 
GGAAGTAGGG GTGCACCTCA GCACTATCCC AAGACTGCTG GCAACAGCGA GTTCCTGGGG 
AAAACCCCAG GGCAAAACGC TCAGAAATGG ATTCCTGCAC GAAGCACTAG ACGAGATGAC 
AACTCCGCAG CAAACAACTC CGCAAATGAA AAAGAACGAC ATGATGCAAT CTTCAGGAAA 
GTAAGAGGCA TACTAAATAA GCTTACTCCT GAAAAGTTTG ACAAGCTATG CCTTGAGCTC 
CTCAATGTGG GTGTAGAGTC TAAACTCATC CTTAAAGGGG TCATACTGCT GATTGTGGAC 
AAAGCCTTAG AAGAGCCAAA GTATAGCTCG CTGTATGCTC AGCTATGTCT GCGATTGGCA 
GAAGATGCAC CAAACTTTGA TGGCCCAGCA GCAGAGGGTC AACCAGGACA GAAGCAAAGC 
ACAACATTCA GACGCCTCTT GATTTCCAAA TTGCAAGATG AATTTGAAAA CCGAACCAGA 
AATGTTGATG TCTATGATAA GCGTGAAAAT CCCCTCCTTC CTGAGGAGGA GGAACAGAGA 
GCCATTGCTA AGATCAAGAT GTTGGGGAAC ATCAAATTCA TTGGAGAACT TGGCAAGCTT 
GATCTTATTC ATGAATCTAT CCTTCATAAG TGCATCAAAA CACTTTTGGA AAAGAAGAAG 
AGAGTCCAAC TCAAAGATAT GGGAGAGGAT TTGGAGTGCC TCTGTCAGAT AATGAGGACA 
GTGGGACCTC GATTAGACCA TGAACGAGCC AAGTCCTTAA TGGATCAGTA CTTTGCCAGA 
ATGTGTTCCT TAATGTTAAG TAAGGAATTG CCAGCCAGGA TTCGTTTCCT ACTGCAGGAT 
ACTGTAGAGT TGCGAGAGCA CCATTGGGTT CCTCGCAAGG CTTTTCTTGA CAATGGACCA 
AAGACGATCA ATCAAATCCG TCAAGATGCA GTAAAAGATC TAGGAGTGTT TATTCCTGCT 
CCTATGGCTC AAGGGAGGAA TGACTTCTTC CTGGAGGGAC CGTTCATGCC GCCAAGGATG 
AAAATGGATA GGGACCCACT TGGGGGACTT GCTGATATGT TTGGACAAAT GCCAGGTAGT 
GGAATTGGTA CTGGTCCAGG AGTTATCCAG GATAGATTTT CACCCACAAT GGGACGTCAT 
CGTTCAAATC AGCTCTTCAA TGGCCATGGG GGGCACATCA TGCCTCCCAC GCAATCGCAG 
TTTGGAGAGA TGGGGGGCAA GTTTATGAAA AGCCAGATTA GTTTGAGGCC TGCTCAGTCG 
TTTCTAATGA ATAAAAATCA GGTGCCAAAG CTTCAGCCCC AGATAACTAT GATTCCTCCC 
AGTGCACAGC CACCACGCAC TCAAACACCG CCTCTGGGAC AGACACCTCA ACTTGGTCTC 
AAAACTAATC CACCACTTAT CCAGGAAAAG CCTGCCAAGA CTAGCAAAAA GCCACCACCA 
TCAAAGGAAG AACTACTTAA ACTGACCGAA GCCGTTGTGA CTGACTATCT GAACAGTGGA 
AATGCCAACG ACGCTGTCAG TGGTGTGAGA GAAATGAGAG CTCCAAAACA CTTTCTTCCT 
GAGATGCTAA GCAAAGTGAT CATCCTGTCA CTTGATAGAA GTGATGAAGA TAAAGAAAAA 
GCAAGCTCTT TAATCAGTTT ACTCAAACAG GAAGGGATAG CCACAAGTGA CAACTTCATG 
CAGGCTTTCC TGAATGTATT GGAGCAGTGC CCCAAACTGG AGGTTGACAT CCCCTTGGTG 
AAATCTTACT TGGCACAGTT TGCAGCTCGT GCTATAATTT CAGAGTTGGT GAGCATTTCC 
GAACTAGCTC AACCACTGGA GAGTGGCACC CACTTCCCTC TCTTCTTACT TTGTCTTCAA 
CAATTAGCTA AATTGCAAGA CCGAGAGTGG TTAACCGAAC TTTTTCAACA AAGCAAGGTC 
AATATGCAGA AAATGCTGCC AGAAATTGAT CAGAATAAGG ATCGAATGTT GGAGATTTTG 
GAAGGAAAGG GACTGAGTTT CTTATTCCCA CTCCTTAAAT TGGAGAAGGA ACTATTGAAG 
CAAATTAAGC TGGATCCATC CCCTCAAACT ATATATAAAT GGATTAAAGA TAACATCTCT 
CCCAAACTTC ATGTAGATAA AGGATTCGTG AACATCTTAA TGACCAGCTT CTTACAGTAC 
ATTTCTAGTG AAGTAAGCCC ACCCAGCGAT GAAACAGATT CTTCCTCTGC TCCTTCCAAA 
GAGCAGTTAG AGCAGGAAAA ACAGCTGCTG CTCTCTTTTA AGCCAGTGAT GCAGAAATTT 
CTTCATGATC ATGTGGATCT ACAGGTCAGT GCCCTGTATG CTTTGCAGGT GCACTGTTAC 
AACAGCAGCT TCCCAAAAGG CATGTTACTT CGATTTTTTG TTCACTTCTA TGACATGGAA 
ATTATTGAAG AGGAAGCTTT CTTAGCTTGG AAGGAAGACA TAACTCAAGA GTTTCCAGGA 
AAAGGCAAGG CTTTGTTCCA GGTGAATCAG TGGCTAACCT GGCTAGAAAC TGCTGAAGAA 
GAAGAATCAG AGGAAGAAGC TGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035221.1
CDS	333..2939
Translation	VESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGRNDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTEAVVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD

Target ORF information:

RefSeq Version	NM_001040131.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040131.2

ORF Insert Sequence:

GTGGAGAGTG CGATTGCAGA AGGGGGTGCT TCTCGTTTCA GTGCTTCTTC GGGCGGAGGA 
GGAAGTAGGG GTGCACCTCA GCACTATCCC AAGACTGCTG GCAACAGCGA GTTCCTGGGG 
AAAACCCCAG GGCAAAACGC TCAGAAATGG ATTCCTGCAC GAAGCACTAG ACGAGATGAC 
AACTCCGCAG CAAACAACTC CGCAAATGAA AAAGAACGAC ATGATGCAAT CTTCAGGAAA 
GTAAGAGGCA TACTAAATAA GCTTACTCCT GAAAAGTTTG ACAAGCTATG CCTTGAGCTC 
CTCAATGTGG GTGTAGAGTC TAAACTCATC CTTAAAGGGG TCATACTGCT GATTGTGGAC 
AAAGCCTTAG AAGAGCCAAA GTATAGCTCG CTGTATGCTC AGCTATGTCT GCGATTGGCA 
GAAGATGCAC CAAACTTTGA TGGCCCAGCA GCAGAGGGTC AACCAGGACA GAAGCAAAGC 
ACAACATTCA GACGCCTCTT GATTTCCAAA TTGCAAGATG AATTTGAAAA CCGAACCAGA 
AATGTTGATG TCTATGATAA GCGTGAAAAT CCCCTCCTTC CTGAGGAGGA GGAACAGAGA 
GCCATTGCTA AGATCAAGAT GTTGGGGAAC ATCAAATTCA TTGGAGAACT TGGCAAGCTT 
GATCTTATTC ATGAATCTAT CCTTCATAAG TGCATCAAAA CACTTTTGGA AAAGAAGAAG 
AGAGTCCAAC TCAAAGATAT GGGAGAGGAT TTGGAGTGCC TCTGTCAGAT AATGAGGACA 
GTGGGACCTC GATTAGACCA TGAACGAGCC AAGTCCTTAA TGGATCAGTA CTTTGCCAGA 
ATGTGTTCCT TAATGTTAAG TAAGGAATTG CCAGCCAGGA TTCGTTTCCT ACTGCAGGAT 
ACTGTAGAGT TGCGAGAGCA CCATTGGGTT CCTCGCAAGG CTTTTCTTGA CAATGGACCA 
AAGACGATCA ATCAAATCCG TCAAGATGCA GTAAAAGATC TAGGAGTGTT TATTCCTGCT 
CCTATGGCTC AAGGGAGGAA TGACTTCTTC CTGGAGGGAC CGTTCATGCC GCCAAGGATG 
AAAATGGATA GGGACCCACT TGGGGGACTT GCTGATATGT TTGGACAAAT GCCAGGTAGT 
GGAATTGGTA CTGGTCCAGG AGTTATCCAG GATAGATTTT CACCCACAAT GGGACGTCAT 
CGTTCAAATC AGCTCTTCAA TGGCCATGGG GGGCACATCA TGCCTCCCAC GCAATCGCAG 
TTTGGAGAGA TGGGGGGCAA GTTTATGAAA AGCCAGATTA GTTTGAGGCC TGCTCAGTCG 
TTTCTAATGA ATAAAAATCA GGTGCCAAAG CTTCAGCCCC AGATAACTAT GATTCCTCCC 
AGTGCACAGC CACCACGCAC TCAAACACCG CCTCTGGGAC AGACACCTCA ACTTGGTCTC 
AAAACTAATC CACCACTTAT CCAGGAAAAG CCTGCCAAGA CTAGCAAAAA GCCACCACCA 
TCAAAGGAAG AACTACTTAA ACTGACCGAA GCCGTTGTGA CTGACTATCT GAACAGTGGA 
AATGCCAACG ACGCTGTCAG TGGTGTGAGA GAAATGAGAG CTCCAAAACA CTTTCTTCCT 
GAGATGCTAA GCAAAGTGAT CATCCTGTCA CTTGATAGAA GTGATGAAGA TAAAGAAAAA 
GCAAGCTCTT TAATCAGTTT ACTCAAACAG GAAGGGATAG CCACAAGTGA CAACTTCATG 
CAGGCTTTCC TGAATGTATT GGAGCAGTGC CCCAAACTGG AGGTTGACAT CCCCTTGGTG 
AAATCTTACT TGGCACAGTT TGCAGCTCGT GCTATAATTT CAGAGTTGGT GAGCATTTCC 
GAACTAGCTC AACCACTGGA GAGTGGCACC CACTTCCCTC TCTTCTTACT TTGTCTTCAA 
CAATTAGCTA AATTGCAAGA CCGAGAGTGG TTAACCGAAC TTTTTCAACA AAGCAAGGTC 
AATATGCAGA AAATGCTGCC AGAAATTGAT CAGAATAAGG ATCGAATGTT GGAGATTTTG 
GAAGGAAAGG GACTGAGTTT CTTATTCCCA CTCCTTAAAT TGGAGAAGGA ACTATTGAAG 
CAAATTAAGC TGGATCCATC CCCTCAAACT ATATATAAAT GGATTAAAGA TAACATCTCT 
CCCAAACTTC ATGTAGATAA AGGATTCGTG AACATCTTAA TGACCAGCTT CTTACAGTAC 
ATTTCTAGTG AAGTAAGCCC ACCCAGCGAT GAAACAGATT CTTCCTCTGC TCCTTCCAAA 
GAGCAGTTAG AGCAGGAAAA ACAGCTGCTG CTCTCTTTTA AGCCAGTGAT GCAGAAATTT 
CTTCATGATC ATGTGGATCT ACAGGTCAGT GCCCTGTATG CTTTGCAGGT GCACTGTTAC 
AACAGCAGCT TCCCAAAAGG CATGTTACTT CGATTTTTTG TTCACTTCTA TGACATGGAA 
ATTATTGAAG AGGAAGCTTT CTTAGCTTGG AAGGAAGACA TAACTCAAGA GTTTCCAGGA 
AAAGGCAAGG CTTTGTTCCA GGTGAATCAG TGGCTAACCT GGCTAGAAAC TGCTGAAGAA 
GAAGAATCAG AGGAAGAAGC TGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif4g2 ( NM_013507.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038535.2 Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15166
Clone ID Related Accession (Same CDS sequence)	NM_013507.3
Accession Version	NM_013507.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2721bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 4 gamma 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI874618.1, BC043034.1 and AC150312.2. On Jul 24, 2006 this sequence version replaced NM_013507.2. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC127064.1, SRR1660811.246826.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 9027506, 9049310 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

GTGGAGAGTG CGATTGCAGA AGGGGGTGCT TCTCGTTTCA GTGCTTCTTC GGGCGGAGGA 
GGAAGTAGGG GTGCACCTCA GCACTATCCC AAGACTGCTG GCAACAGCGA GTTCCTGGGG 
AAAACCCCAG GGCAAAACGC TCAGAAATGG ATTCCTGCAC GAAGCACTAG ACGAGATGAC 
AACTCCGCAG CAAACAACTC CGCAAATGAA AAAGAACGAC ATGATGCAAT CTTCAGGAAA 
GTAAGAGGCA TACTAAATAA GCTTACTCCT GAAAAGTTTG ACAAGCTATG CCTTGAGCTC 
CTCAATGTGG GTGTAGAGTC TAAACTCATC CTTAAAGGGG TCATACTGCT GATTGTGGAC 
AAAGCCTTAG AAGAGCCAAA GTATAGCTCG CTGTATGCTC AGCTATGTCT GCGATTGGCA 
GAAGATGCAC CAAACTTTGA TGGCCCAGCA GCAGAGGGTC AACCAGGACA GAAGCAAAGC 
ACAACATTCA GACGCCTCTT GATTTCCAAA TTGCAAGATG AATTTGAAAA CCGAACCAGA 
AATGTTGATG TCTATGATAA GCGTGAAAAT CCCCTCCTTC CTGAGGAGGA GGAACAGAGA 
GCCATTGCTA AGATCAAGAT GTTGGGGAAC ATCAAATTCA TTGGAGAACT TGGCAAGCTT 
GATCTTATTC ATGAATCTAT CCTTCATAAG TGCATCAAAA CACTTTTGGA AAAGAAGAAG 
AGAGTCCAAC TCAAAGATAT GGGAGAGGAT TTGGAGTGCC TCTGTCAGAT AATGAGGACA 
GTGGGACCTC GATTAGACCA TGAACGAGCC AAGTCCTTAA TGGATCAGTA CTTTGCCAGA 
ATGTGTTCCT TAATGTTAAG TAAGGAATTG CCAGCCAGGA TTCGTTTCCT ACTGCAGGAT 
ACTGTAGAGT TGCGAGAGCA CCATTGGGTT CCTCGCAAGG CTTTTCTTGA CAATGGACCA 
AAGACGATCA ATCAAATCCG TCAAGATGCA GTAAAAGATC TAGGAGTGTT TATTCCTGCT 
CCTATGGCTC AAGGGAGGAA TGACTTCTTC CTGGAGGGAC CGTTCATGCC GCCAAGGATG 
AAAATGGATA GGGACCCACT TGGGGGACTT GCTGATATGT TTGGACAAAT GCCAGGTAGT 
GGAATTGGTA CTGGTCCAGG AGTTATCCAG GATAGATTTT CACCCACAAT GGGACGTCAT 
CGTTCAAATC AGCTCTTCAA TGGCCATGGG GGGCACATCA TGCCTCCCAC GCAATCGCAG 
TTTGGAGAGA TGGGGGGCAA GTTTATGAAA AGCCAGGGGC TAAGCCAGCT CTACCATAAC 
CAGAGTCAGG GACTCTTATC CCAGCTACAA GGACAGTCGA AGGATATGCC ACCTCGGTTT 
TCTAAGAAAG GACAGCTTAA TGCAGATGAG ATTAGTTTGA GGCCTGCTCA GTCGTTTCTA 
ATGAATAAAA ATCAGGTGCC AAAGCTTCAG CCCCAGATAA CTATGATTCC TCCCAGTGCA 
CAGCCACCAC GCACTCAAAC ACCGCCTCTG GGACAGACAC CTCAACTTGG TCTCAAAACT 
AATCCACCAC TTATCCAGGA AAAGCCTGCC AAGACTAGCA AAAAGCCACC ACCATCAAAG 
GAAGAACTAC TTAAACTGAC CGAAGCCGTT GTGACTGACT ATCTGAACAG TGGAAATGCC 
AACGACGCTG TCAGTGGTGT GAGAGAAATG AGAGCTCCAA AACACTTTCT TCCTGAGATG 
CTAAGCAAAG TGATCATCCT GTCACTTGAT AGAAGTGATG AAGATAAAGA AAAAGCAAGC 
TCTTTAATCA GTTTACTCAA ACAGGAAGGG ATAGCCACAA GTGACAACTT CATGCAGGCT 
TTCCTGAATG TATTGGAGCA GTGCCCCAAA CTGGAGGTTG ACATCCCCTT GGTGAAATCT 
TACTTGGCAC AGTTTGCAGC TCGTGCTATA ATTTCAGAGT TGGTGAGCAT TTCCGAACTA 
GCTCAACCAC TGGAGAGTGG CACCCACTTC CCTCTCTTCT TACTTTGTCT TCAACAATTA 
GCTAAATTGC AAGACCGAGA GTGGTTAACC GAACTTTTTC AACAAAGCAA GGTCAATATG 
CAGAAAATGC TGCCAGAAAT TGATCAGAAT AAGGATCGAA TGTTGGAGAT TTTGGAAGGA 
AAGGGACTGA GTTTCTTATT CCCACTCCTT AAATTGGAGA AGGAACTATT GAAGCAAATT 
AAGCTGGATC CATCCCCTCA AACTATATAT AAATGGATTA AAGATAACAT CTCTCCCAAA 
CTTCATGTAG ATAAAGGATT CGTGAACATC TTAATGACCA GCTTCTTACA GTACATTTCT 
AGTGAAGTAA GCCCACCCAG CGATGAAACA GATTCTTCCT CTGCTCCTTC CAAAGAGCAG 
TTAGAGCAGG AAAAACAGCT GCTGCTCTCT TTTAAGCCAG TGATGCAGAA ATTTCTTCAT 
GATCATGTGG ATCTACAGGT CAGTGCCCTG TATGCTTTGC AGGTGCACTG TTACAACAGC 
AGCTTCCCAA AAGGCATGTT ACTTCGATTT TTTGTTCACT TCTATGACAT GGAAATTATT 
GAAGAGGAAG CTTTCTTAGC TTGGAAGGAA GACATAACTC AAGAGTTTCC AGGAAAAGGC 
AAGGCTTTGT TCCAGGTGAA TCAGTGGCTA ACCTGGCTAG AAACTGCTGA AGAAGAAGAA 
TCAGAGGAAG AAGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038535.2
CDS	333..3053
Translation	VESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGRNDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTEAVVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD

Target ORF information:

RefSeq Version	NM_013507.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013507.3

ORF Insert Sequence:

GTGGAGAGTG CGATTGCAGA AGGGGGTGCT TCTCGTTTCA GTGCTTCTTC GGGCGGAGGA 
GGAAGTAGGG GTGCACCTCA GCACTATCCC AAGACTGCTG GCAACAGCGA GTTCCTGGGG 
AAAACCCCAG GGCAAAACGC TCAGAAATGG ATTCCTGCAC GAAGCACTAG ACGAGATGAC 
AACTCCGCAG CAAACAACTC CGCAAATGAA AAAGAACGAC ATGATGCAAT CTTCAGGAAA 
GTAAGAGGCA TACTAAATAA GCTTACTCCT GAAAAGTTTG ACAAGCTATG CCTTGAGCTC 
CTCAATGTGG GTGTAGAGTC TAAACTCATC CTTAAAGGGG TCATACTGCT GATTGTGGAC 
AAAGCCTTAG AAGAGCCAAA GTATAGCTCG CTGTATGCTC AGCTATGTCT GCGATTGGCA 
GAAGATGCAC CAAACTTTGA TGGCCCAGCA GCAGAGGGTC AACCAGGACA GAAGCAAAGC 
ACAACATTCA GACGCCTCTT GATTTCCAAA TTGCAAGATG AATTTGAAAA CCGAACCAGA 
AATGTTGATG TCTATGATAA GCGTGAAAAT CCCCTCCTTC CTGAGGAGGA GGAACAGAGA 
GCCATTGCTA AGATCAAGAT GTTGGGGAAC ATCAAATTCA TTGGAGAACT TGGCAAGCTT 
GATCTTATTC ATGAATCTAT CCTTCATAAG TGCATCAAAA CACTTTTGGA AAAGAAGAAG 
AGAGTCCAAC TCAAAGATAT GGGAGAGGAT TTGGAGTGCC TCTGTCAGAT AATGAGGACA 
GTGGGACCTC GATTAGACCA TGAACGAGCC AAGTCCTTAA TGGATCAGTA CTTTGCCAGA 
ATGTGTTCCT TAATGTTAAG TAAGGAATTG CCAGCCAGGA TTCGTTTCCT ACTGCAGGAT 
ACTGTAGAGT TGCGAGAGCA CCATTGGGTT CCTCGCAAGG CTTTTCTTGA CAATGGACCA 
AAGACGATCA ATCAAATCCG TCAAGATGCA GTAAAAGATC TAGGAGTGTT TATTCCTGCT 
CCTATGGCTC AAGGGAGGAA TGACTTCTTC CTGGAGGGAC CGTTCATGCC GCCAAGGATG 
AAAATGGATA GGGACCCACT TGGGGGACTT GCTGATATGT TTGGACAAAT GCCAGGTAGT 
GGAATTGGTA CTGGTCCAGG AGTTATCCAG GATAGATTTT CACCCACAAT GGGACGTCAT 
CGTTCAAATC AGCTCTTCAA TGGCCATGGG GGGCACATCA TGCCTCCCAC GCAATCGCAG 
TTTGGAGAGA TGGGGGGCAA GTTTATGAAA AGCCAGGGGC TAAGCCAGCT CTACCATAAC 
CAGAGTCAGG GACTCTTATC CCAGCTACAA GGACAGTCGA AGGATATGCC ACCTCGGTTT 
TCTAAGAAAG GACAGCTTAA TGCAGATGAG ATTAGTTTGA GGCCTGCTCA GTCGTTTCTA 
ATGAATAAAA ATCAGGTGCC AAAGCTTCAG CCCCAGATAA CTATGATTCC TCCCAGTGCA 
CAGCCACCAC GCACTCAAAC ACCGCCTCTG GGACAGACAC CTCAACTTGG TCTCAAAACT 
AATCCACCAC TTATCCAGGA AAAGCCTGCC AAGACTAGCA AAAAGCCACC ACCATCAAAG 
GAAGAACTAC TTAAACTGAC CGAAGCCGTT GTGACTGACT ATCTGAACAG TGGAAATGCC 
AACGACGCTG TCAGTGGTGT GAGAGAAATG AGAGCTCCAA AACACTTTCT TCCTGAGATG 
CTAAGCAAAG TGATCATCCT GTCACTTGAT AGAAGTGATG AAGATAAAGA AAAAGCAAGC 
TCTTTAATCA GTTTACTCAA ACAGGAAGGG ATAGCCACAA GTGACAACTT CATGCAGGCT 
TTCCTGAATG TATTGGAGCA GTGCCCCAAA CTGGAGGTTG ACATCCCCTT GGTGAAATCT 
TACTTGGCAC AGTTTGCAGC TCGTGCTATA ATTTCAGAGT TGGTGAGCAT TTCCGAACTA 
GCTCAACCAC TGGAGAGTGG CACCCACTTC CCTCTCTTCT TACTTTGTCT TCAACAATTA 
GCTAAATTGC AAGACCGAGA GTGGTTAACC GAACTTTTTC AACAAAGCAA GGTCAATATG 
CAGAAAATGC TGCCAGAAAT TGATCAGAAT AAGGATCGAA TGTTGGAGAT TTTGGAAGGA 
AAGGGACTGA GTTTCTTATT CCCACTCCTT AAATTGGAGA AGGAACTATT GAAGCAAATT 
AAGCTGGATC CATCCCCTCA AACTATATAT AAATGGATTA AAGATAACAT CTCTCCCAAA 
CTTCATGTAG ATAAAGGATT CGTGAACATC TTAATGACCA GCTTCTTACA GTACATTTCT 
AGTGAAGTAA GCCCACCCAG CGATGAAACA GATTCTTCCT CTGCTCCTTC CAAAGAGCAG 
TTAGAGCAGG AAAAACAGCT GCTGCTCTCT TTTAAGCCAG TGATGCAGAA ATTTCTTCAT 
GATCATGTGG ATCTACAGGT CAGTGCCCTG TATGCTTTGC AGGTGCACTG TTACAACAGC 
AGCTTCCCAA AAGGCATGTT ACTTCGATTT TTTGTTCACT TCTATGACAT GGAAATTATT 
GAAGAGGAAG CTTTCTTAGC TTGGAAGGAA GACATAACTC AAGAGTTTCC AGGAAAAGGC 
AAGGCTTTGT TCCAGGTGAA TCAGTGGCTA ACCTGGCTAG AAACTGCTGA AGAAGAAGAA 
TCAGAGGAAG AAGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Thyroid hormone increases bulk histones expression by enhancing translational efficiency.
Molecular endocrinology (Baltimore, Md.)29(1)68-75(2015 Jan)
Zambrano A,Garc?a-Carpizo V,Villamuera R,Aranda A

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Proteomics14(21-22)2607-13(2014 Nov)
Distler U,Schmeisser MJ,Pelosi A,Reim D,Kuharev J,Weiczner R,Baumgart J,Boeckers TM,Nitsch R,Vogt J,Tenzer S

Blastocyst implantation failure relates to impaired translational machinery gene expression.
Reproduction (Cambridge, England)148(1)87-98(2014 Jul)
Plaks V,Gershon E,Zeisel A,Jacob-Hirsch J,Neeman M,Winterhager E,Rechavi G,Domany E,Dekel N

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Eif4g2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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