Calm3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Calm3
Entrez Gene ID	12315
Full Name	calmodulin 3
Synonyms	CaMA,Cam3,Camc,R75142
General protein information	Preferred Names calmodulin 3 Names calmodulin-3 caM
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 A2\|7 9.15 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007590.3	NP_031616.1	calmodulin-3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CALM3	XP_533635.1
Bos taurus (cattle)	CALM3	NP_001039714.1
Mus musculus (house mouse)	Calm1	NP_033920.1
Mus musculus (house mouse)	Calm2	NP_031615.1
Rattus norvegicus (Norway rat)	Calm2	NP_059022.1
Danio rerio (zebrafish)	calm1b	NP_956376.1
Danio rerio (zebrafish)	calm3b	NP_955864.1
Canis lupus familiaris (dog)	CALM2	XP_864645.2
Mus musculus (house mouse)	Calm3	NP_031616.1
Drosophila melanogaster (fruit fly)	Cam	NP_001246276.1
Xenopus tropicalis (tropical clawed frog)	calm2	NP_001008160.1
Pan troglodytes (chimpanzee)	CALM1	NP_001104289.1
Canis lupus familiaris (dog)	CALM1	XP_537537.1
Bos taurus (cattle)	CALM1	NP_001229501.1
Rattus norvegicus (Norway rat)	Calm3	NP_036650.1
Rattus norvegicus (Norway rat)	Calm1	NP_114175.1
Danio rerio (zebrafish)	calm2a	NP_956290.1
Caenorhabditis elegans (roundworm)	cmd-1	NP_503386.1
Arabidopsis thaliana (thale cress)	CAM2	NP_001189724.1
Oryza sativa (rice)	Os01g0279300	NP_001042747.1
Xenopus tropicalis (tropical clawed frog)	LOC100496298	XP_002932424.1
	LOC706351	XP_001094720.1
Bos taurus (cattle)	CALM2	NP_001229516.1
Danio rerio (zebrafish)	calm1a	NP_998516.1
Danio rerio (zebrafish)	calm2b	NP_999901.1
Gallus gallus (chicken)	CALM	NP_990336.1
Danio rerio (zebrafish)	calm3a	NP_892012.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010957	XP_309749.4

Gene Ontology
Bibliography

Related articles in PubMed

The proximal C-terminus of ?(1C) subunits is necessary for junctional membrane targeting of cardiac L-type calcium channels.
Nakada T, Flucher BE, Kashihara T, Sheng X, Shibazaki T, Horiuchi-Hirose M, Gomi S, Hirose M, Yamada M
The Biochemical journal448(2)221-31(2012 Dec)

Fibronectin stimulates migration through lipid raft dependent NHE-1 activation in mouse embryonic stem cells: involvement of RhoA, Ca(2+)/CaM, and ERK.
Park JH, Ryu JM, Yun SP, Kim MO, Han HJ
Biochimica et biophysica acta1820(10)1618-27(2012 Oct)

Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors.
Gerasimenko JV, Lur G, Ferdek P, Sherwood MW, Ebisui E, Tepikin AV, Mikoshiba K, Petersen OH, Gerasimenko OV
Proceedings of the National Academy of Sciences of the United States of America108(14)5873-8(2011 Apr)

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule.
Majava V, Wang C, Myllykoski M, Kangas SM, Kang SU, Hayashi N, Baumg?rtel P, Heape AM, Lubec G, Kursula P
Amino acids39(1)59-71(2010 Jun)

Cdx2 regulates endo-lysosomal function and epithelial cell polarity.
Gao N, Kaestner KH
Genes & development24(12)1295-305(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Calmodulin (CaM) has three separate nonallelic genes that encode for three identical proteins.
Title: Sequence homology of the 3'-untranslated region of calmodulin III in mammals.

The following Calm3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Calm3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15040	NM_007590.3 Latest version!	Mus musculus calmodulin 3 (Calm3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Calm3 ( NM_007590.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031616.1 Mus musculus calmodulin 3 (Calm3), mRNA.

Price & Availability↑

CloneID	OMu15040
Clone ID Related Accession (Same CDS sequence)	NM_007590.3
Accession Version	NM_007590.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	calmodulin-3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE853985.1 and BC050926.1. On or before Dec 17, 2010 this sequence version replaced XR_107871.1, XR_105094.1, NM_007590.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK151610.1, AK165568.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGACC AGCTGACTGA GGAACAGATT GCAGAGTTCA AGGAAGCCTT CTCCCTCTTC 
GACAAGGATG GAGATGGCAC CATTACCACC AAGGAGCTGG GGACTGTGAT GAGATCGCTG 
GGACAGAACC CCACTGAGGC GGAGCTGCAG GACATGATTA ATGAGGTGGA TGCTGATGGC 
AATGGGACCA TTGACTTCCC AGAGTTCTTG ACCATGATGG CCAGAAAGAT GAAGGATACA 
GACAGCGAGG AGGAGATACG AGAGGCCTTC CGTGTCTTTG ACAAGGATGG GAATGGCTAT 
ATTAGCGCTG CCGAGCTGCG TCACGTCATG ACGAACCTGG GGGAGAAGCT GACAGATGAG 
GAAGTGGATG AGATGATCCG AGAGGCCGAC ATTGATGGAG ATGGCCAGGT CAATTATGAA 
GAGTTTGTAC AGATGATGAC TGCGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031616.1
CDS	190..639
Translation	MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

Target ORF information:

RefSeq Version	NM_007590.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus calmodulin 3 (Calm3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007590.3

ORF Insert Sequence:

ATGGCTGACC AGCTGACTGA GGAACAGATT GCAGAGTTCA AGGAAGCCTT CTCCCTCTTC 
GACAAGGATG GAGATGGCAC CATTACCACC AAGGAGCTGG GGACTGTGAT GAGATCGCTG 
GGACAGAACC CCACTGAGGC GGAGCTGCAG GACATGATTA ATGAGGTGGA TGCTGATGGC 
AATGGGACCA TTGACTTCCC AGAGTTCTTG ACCATGATGG CCAGAAAGAT GAAGGATACA 
GACAGCGAGG AGGAGATACG AGAGGCCTTC CGTGTCTTTG ACAAGGATGG GAATGGCTAT 
ATTAGCGCTG CCGAGCTGCG TCACGTCATG ACGAACCTGG GGGAGAAGCT GACAGATGAG 
GAAGTGGATG AGATGATCCG AGAGGCCGAC ATTGATGGAG ATGGCCAGGT CAATTATGAA 
GAGTTTGTAC AGATGATGAC TGCGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The proximal C-terminus of ?(1C) subunits is necessary for junctional membrane targeting of cardiac L-type calcium channels.
The Biochemical journal448(2)221-31(2012 Dec)
Nakada T,Flucher BE,Kashihara T,Sheng X,Shibazaki T,Horiuchi-Hirose M,Gomi S,Hirose M,Yamada M

Fibronectin stimulates migration through lipid raft dependent NHE-1 activation in mouse embryonic stem cells: involvement of RhoA, Ca(2+)/CaM, and ERK.
Biochimica et biophysica acta1820(10)1618-27(2012 Oct)
Park JH,Ryu JM,Yun SP,Kim MO,Han HJ

Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors.
Proceedings of the National Academy of Sciences of the United States of America108(14)5873-8(2011 Apr)
Gerasimenko JV,Lur G,Ferdek P,Sherwood MW,Ebisui E,Tepikin AV,Mikoshiba K,Petersen OH,Gerasimenko OV

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule.
Amino acids39(1)59-71(2010 Jun)
Majava V,Wang C,Myllykoski M,Kangas SM,Kang SU,Hayashi N,Baumg?rtel P,Heape AM,Lubec G,Kursula P

Cdx2 regulates endo-lysosomal function and epithelial cell polarity.
Genes & development24(12)1295-305(2010 Jun)
Gao N,Kaestner KH