Cdc42ep1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdc42ep1
Entrez Gene ID	104445
Full Name	CDC42 effector protein (Rho GTPase binding) 1
Synonyms	1810058K22Rik,AA980734,Borg5,CEP1,MSE55
General protein information	Preferred Names CDC42 effector protein (Rho GTPase binding) 1 Names cdc42 effector protein 1 binder of Rho GTPase 5 binder of Rho GTPases 5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_027219.3	NP_081495.1	cdc42 effector protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CDC42EP1	NP_689449.1
	CDC42EP1	XP_001086940.1
Rattus norvegicus (Norway rat)	Cdc42ep1	NP_001073168.1
Bos taurus (cattle)	CDC42EP1	NP_001068963.1
Gallus gallus (chicken)	CDC42EP1	XP_429544.4
Canis lupus familiaris (dog)	CDC42EP1	XP_005626276.1
Mus musculus (house mouse)	Cdc42ep1	NP_081495.1
Pan troglodytes (chimpanzee)	CDC42EP1	XP_003317296.1

Gene Ontology
Bibliography

Related articles in PubMed

Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells.
Liu Z, Vong QP, Liu C, Zheng Y
Molecular biology of the cell25(6)841-51(2014 Mar)

A role for borg5 during trophectoderm differentiation.
Vong QP, Liu Z, Yoo JG, Chen R, Xie W, Sharov AA, Fan CM, Liu C, Ko MS, Zheng Y
Stem cells (Dayton, Ohio)28(6)1030-8(2010 Jun)

Phosphoproteomic analysis of the developing mouse brain.
Ballif BA, Vill?n J, Beausoleil SA, Schwartz D, Gygi SP
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)

A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.
Hirsch DS, Pirone DM, Burbelo PD
The Journal of biological chemistry276(2)875-83(2001 Jan)

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.
Joberty G, Perlungher RR, Macara IG
Molecular and cellular biology19(10)6585-97(1999 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells.
Title: Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells.

report that differentiation of embryonic stem cells toward trophectoderm is accompanied by enhanced actin protrusion and cell motility that require upregulation of Borg5.
Title: A role for borg5 during trophectoderm differentiation.

The following Cdc42ep1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc42ep1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03889	NM_027219.3 Latest version!	Mus musculus CDC42 effector protein (Rho GTPase binding) 1 (Cdc42ep1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdc42ep1 ( NM_027219.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081495.1 Mus musculus CDC42 effector protein (Rho GTPase binding) 1 (Cdc42ep1), mRNA.

Price & Availability↑

CloneID	OMu03889
Clone ID Related Accession (Same CDS sequence)	NM_027219.3
Accession Version	NM_027219.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	cdc42 effector protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL592169.14. On Apr 30, 2007 this sequence version replaced NM_027219.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK007896.1, BC083130.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCGGTC CCCAGGGGGG CACAGGAGCC CCCACCATGA GCCTGGGCAA GCTGTCTCCT 
GTGGGATGGG TGTCCAGTTC CCATGGAAAG AGACGCCTGA CAGCAGACAT GATCAGCCCC 
CCACTTGGGG ACTTCCGCCA CACCATGCAC GTAGGCCGTG GTGGGGATGT CTTCGGAGAT 
ACGTCCTTCC TCAGCAACCA CGGAGGCCGC TCTGGAAACA CCCACCGCTC ACCCCGAAGT 
TTCCTGGCCA GGAAGCTCCA ACAGGTTCGC AGAGTCGGGG TGCCACCTCG AAGGATGGCT 
TCCCCGGCTG CACCATCACC TGCTCCGCCT CCCATCTCGC CCATCATCAA GAACGCCATC 
TCCCTGCCTC AGCTCAACCA GGCCACCTAT GACAGTCTGG TGATGGGCAA GCTTAGTTTT 
GACAGCACGC CGGCTAGCTC CACAGATGGC CACTCTGGTT ACGGCCTGGA GTCTGGCTTC 
TGCACCATCT CACGCCTGCC ACGCGTGGAA AAGCACAGCA ACCGTGACCG TGACCGTGAC 
CCGGACCATT CTCAAGACCG AGAGCAAAGT TCTTTCCCCT CTGAGCCTAC CCCTAACCCT 
GAGCTCCGAC GCTCTGACTC TCTCTTGTCC TTCCGTTTTG ACCTTGACCT TGGGCCCTCA 
CTCCTCAGTG AGCTGCTAGG GGTCATGAGC CTTTCAGAAG CTCCAGCTGC TGAAACTCCA 
GTCCCTACTG CCAACCCCCC TGCTCCTGCA GCAAACCCTG CCCCTACTGC AAAACCCCCA 
GCCCATGCGA TAACCACTCT AGATGCTGTG ACAAGCCTTC CAGCCTCTGC TGTGACAAGC 
CTTCCAGCCC CTGCGGTGGC AAGCTCCCCA TCCCGTGGAC ATTTCCCCAA TGGGGTAACT 
TCTGTGTTGG GCCCTGCGGC TGAGGCAAAG CCCAGTCCTG TGGGAGAGGG TCCCCAGGTA 
CCCTCCAACA TGGCCTTTGA CAGGCATGGA GCCAGCTGGG GGGCCAGCCG GGCCAGCTGG 
GGGGCCAGCC GGGCCAGCCG CCACTACACT GAGATGGATG CCCGGCGGGA GCTGGCAGGG 
GTGTTACCCC AAGTTCATGG CTCCTGGGAG AGTCTGAATG AAGACTGGAG CGCGCCTCCA 
GCCAGTGTCA GGGCTCCTGT GCCCACCTCG GTGCAGGTCA ATGCCTTTGA GTTTGCTGAT 
GCTGAGGAAG ATGACGAGGT CAAGGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081495.1
CDS	342..1571
Translation	MPGPQGGTGAPTMSLGKLSPVGWVSSSHGKRRLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGRSGNTHRSPRSFLARKLQQVRRVGVPPRRMASPAAPSPAPPPISPIIKNAISLPQLNQATYDSLVMGKLSFDSTPASSTDGHSGYGLESGFCTISRLPRVEKHSNRDRDRDPDHSQDREQSSFPSEPTPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAETPVPTANPPAPAANPAPTAKPPAHAITTLDAVTSLPASAVTSLPAPAVASSPSRGHFPNGVTSVLGPAAEAKPSPVGEGPQVPSNMAFDRHGASWGASRASWGASRASRHYTEMDARRELAGVLPQVHGSWESLNEDWSAPPASVRAPVPTSVQVNAFEFADAEEDDEVKV

Target ORF information:

RefSeq Version	NM_027219.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus CDC42 effector protein (Rho GTPase binding) 1 (Cdc42ep1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027219.3

ORF Insert Sequence:

ATGCCCGGTC CCCAGGGGGG CACAGGAGCC CCCACCATGA GCCTGGGCAA GCTGTCTCCT 
GTGGGATGGG TGTCCAGTTC CCATGGAAAG AGACGCCTGA CAGCAGACAT GATCAGCCCC 
CCACTTGGGG ACTTCCGCCA CACCATGCAC GTAGGCCGTG GTGGGGATGT CTTCGGAGAT 
ACGTCCTTCC TCAGCAACCA CGGAGGCCGC TCTGGAAACA CCCACCGCTC ACCCCGAAGT 
TTCCTGGCCA GGAAGCTCCA ACAGGTTCGC AGAGTCGGGG TGCCACCTCG AAGGATGGCT 
TCCCCGGCTG CACCATCACC TGCTCCGCCT CCCATCTCGC CCATCATCAA GAACGCCATC 
TCCCTGCCTC AGCTCAACCA GGCCACCTAT GACAGTCTGG TGATGGGCAA GCTTAGTTTT 
GACAGCACGC CGGCTAGCTC CACAGATGGC CACTCTGGTT ACGGCCTGGA GTCTGGCTTC 
TGCACCATCT CACGCCTGCC ACGCGTGGAA AAGCACAGCA ACCGTGACCG TGACCGTGAC 
CCGGACCATT CTCAAGACCG AGAGCAAAGT TCTTTCCCCT CTGAGCCTAC CCCTAACCCT 
GAGCTCCGAC GCTCTGACTC TCTCTTGTCC TTCCGTTTTG ACCTTGACCT TGGGCCCTCA 
CTCCTCAGTG AGCTGCTAGG GGTCATGAGC CTTTCAGAAG CTCCAGCTGC TGAAACTCCA 
GTCCCTACTG CCAACCCCCC TGCTCCTGCA GCAAACCCTG CCCCTACTGC AAAACCCCCA 
GCCCATGCGA TAACCACTCT AGATGCTGTG ACAAGCCTTC CAGCCTCTGC TGTGACAAGC 
CTTCCAGCCC CTGCGGTGGC AAGCTCCCCA TCCCGTGGAC ATTTCCCCAA TGGGGTAACT 
TCTGTGTTGG GCCCTGCGGC TGAGGCAAAG CCCAGTCCTG TGGGAGAGGG TCCCCAGGTA 
CCCTCCAACA TGGCCTTTGA CAGGCATGGA GCCAGCTGGG GGGCCAGCCG GGCCAGCTGG 
GGGGCCAGCC GGGCCAGCCG CCACTACACT GAGATGGATG CCCGGCGGGA GCTGGCAGGG 
GTGTTACCCC AAGTTCATGG CTCCTGGGAG AGTCTGAATG AAGACTGGAG CGCGCCTCCA 
GCCAGTGTCA GGGCTCCTGT GCCCACCTCG GTGCAGGTCA ATGCCTTTGA GTTTGCTGAT 
GCTGAGGAAG ATGACGAGGT CAAGGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells.
Molecular biology of the cell25(6)841-51(2014 Mar)
Liu Z,Vong QP,Liu C,Zheng Y

A role for borg5 during trophectoderm differentiation.
Stem cells (Dayton, Ohio)28(6)1030-8(2010 Jun)
Vong QP,Liu Z,Yoo JG,Chen R,Xie W,Sharov AA,Fan CM,Liu C,Ko MS,Zheng Y

Phosphoproteomic analysis of the developing mouse brain.
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)
Ballif BA,Vill?n J,Beausoleil SA,Schwartz D,Gygi SP

A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.
The Journal of biological chemistry276(2)875-83(2001 Jan)
Hirsch DS,Pirone DM,Burbelo PD

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.
Molecular and cellular biology19(10)6585-97(1999 Oct)
Joberty G,Perlungher RR,Macara IG