Tmed4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmed4
Entrez Gene ID	103694
Full Name	transmembrane p24 trafficking protein 4
Synonyms	1110014L17Rik,AI326346
General protein information	Preferred Names transmembrane p24 trafficking protein 4 Names transmembrane emp24 domain-containing protein 4 ERS25 endoplasmic reticulum stress-response protein 25 p24 family protein alpha-3 p24alpha3 p26 transmembrane emp24 protein transport domain containing 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_134020.1	NP_598781.1	transmembrane emp24 domain-containing protein 4 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMED4	NP_872353.2
Pan troglodytes (chimpanzee)	TMED4	XP_001145929.1
Bos taurus (cattle)	TMED4	NP_001193362.1
Mus musculus (house mouse)	Tmed4	NP_598781.1
Caenorhabditis elegans (roundworm)	CELE_Y60A3A.9	NP_507861.1
Schizosaccharomyces pombe (fission yeast)	SPBC16E9.09c	NP_595791.1
	TMED4	XP_001091631.1
Gallus gallus (chicken)	LOC100859485	XP_003643574.1
Danio rerio (zebrafish)	tmed4	NP_001002134.1
Drosophila melanogaster (fruit fly)	p24-2	NP_788617.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003553	XP_562397.3
Magnaporthe oryzae (rice blast fungus)	MGG_08096	XP_003715051.1
Neurospora crassa	NCU04003	XP_957618.1
Xenopus tropicalis (tropical clawed frog)	tmed4	NP_001015779.1
Rattus norvegicus (Norway rat)	Tmed4	NP_001100708.1
Saccharomyces cerevisiae (baker's yeast)	ERP6	NP_011513.1
Eremothecium gossypii	AGOS_AFL005W	NP_985543.1
Kluyveromyces lactis	KLLA0A08778g	XP_451385.1
Canis lupus familiaris (dog)	TMED4	XP_532721.3
Drosophila melanogaster (fruit fly)	eca	NP_788616.1
Saccharomyces cerevisiae (baker's yeast)	ERP1	NP_009402.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel oxidative stress-responsive gene ERS25 functions as a regulator of the heat-shock and cell death response.
Hwang SO, Boswell SA, Seo JS, Lee SW
The Journal of biological chemistry283(19)13063-9(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ERS25 may play a critical role in regulation of heat-shock response and apoptosis
Title: Novel oxidative stress-responsive gene ERS25 functions as a regulator of the heat-shock and cell death response.

The following Tmed4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmed4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18564	NM_134020.1 Latest version!	Mus musculus transmembrane p24 trafficking protein 4 (Tmed4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmed4 ( NM_134020.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598781.1 Mus musculus transmembrane p24 trafficking protein 4 (Tmed4), mRNA.

Price & Availability↑

CloneID	OMu18564
Clone ID Related Accession (Same CDS sequence)	NM_134020.1
Accession Version	NM_134020.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Mus musculus(house mouse)
Product	transmembrane emp24 domain-containing protein 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC023041.1. ##Evidence-Data-START## Transcript exon combination :: BC023041.1, SRR1660811.8902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGTG TTGGGGTCGG ACCGCTGCAG GGGATGGTGC GATTTGGGCT GCTGGTGCTT 
ACTGTGTGTG CTGCGTGTGC CCGTGGGCTC TATTTCCACA TCGGCGAGAC TGAGAAGCGC 
TGCTTCATCG AGGAAATACC CGACGAGACC ATGGTCATCG GCAACTATCG AACTCAGATG 
TGGGACAAAC AGAAAGAGGT GTTCCTGCCG TCGACCCCCG GCCTGGGCAT GCATGTAGAG 
GTGAAGGACC CGGACGGCAA GGTTGTACTG TCCCGGCAAT ACGGCTCCGA GGGCCGTTTC 
ACGTTCACAT CCCACACACC CGGTGACCAT CAGATTTGTC TTCACTCCAA CTCCACCAGA 
ATGGCTCTCT TCGCTGGAGG CAAACTGCGT GTACACTTGG ACATCCAGGT TGGAGAGCAT 
GCCAACAACT ACCCCGAGAT CGCTGCTAAG GATAAGTTAA CAGAGCTCCA GCTTCGAGCT 
CGCCAGTTGC TTGACCAGGT GGAACAGATC CAGAAGGAGC AGGATTATCA GAGGTATCGT 
GAAGAGCGCT TCCGTCTGAC CAGTGAGAGC ACCAACCAGA GGGTCCTGTG GTGGTCCATC 
GCCCAGACCG TTATCCTCAT CCTCACTGGC ATCTGGCAGA TGCGTCACCT CAAGAGCTTC 
TTTGAGGCCA AGAAGCTGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598781.1
CDS	5..688
Translation	MAGVGVGPLQGMVRFGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV

Target ORF information:

RefSeq Version	NM_134020.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane p24 trafficking protein 4 (Tmed4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134020.1

ORF Insert Sequence:

ATGGCAGGTG TTGGGGTCGG ACCGCTGCAG GGGATGGTGC GATTTGGGCT GCTGGTGCTT 
ACTGTGTGTG CTGCGTGTGC CCGTGGGCTC TATTTCCACA TCGGCGAGAC TGAGAAGCGC 
TGCTTCATCG AGGAAATACC CGACGAGACC ATGGTCATCG GCAACTATCG AACTCAGATG 
TGGGACAAAC AGAAAGAGGT GTTCCTGCCG TCGACCCCCG GCCTGGGCAT GCATGTAGAG 
GTGAAGGACC CGGACGGCAA GGTTGTACTG TCCCGGCAAT ACGGCTCCGA GGGCCGTTTC 
ACGTTCACAT CCCACACACC CGGTGACCAT CAGATTTGTC TTCACTCCAA CTCCACCAGA 
ATGGCTCTCT TCGCTGGAGG CAAACTGCGT GTACACTTGG ACATCCAGGT TGGAGAGCAT 
GCCAACAACT ACCCCGAGAT CGCTGCTAAG GATAAGTTAA CAGAGCTCCA GCTTCGAGCT 
CGCCAGTTGC TTGACCAGGT GGAACAGATC CAGAAGGAGC AGGATTATCA GAGGTATCGT 
GAAGAGCGCT TCCGTCTGAC CAGTGAGAGC ACCAACCAGA GGGTCCTGTG GTGGTCCATC 
GCCCAGACCG TTATCCTCAT CCTCACTGGC ATCTGGCAGA TGCGTCACCT CAAGAGCTTC 
TTTGAGGCCA AGAAGCTGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel oxidative stress-responsive gene ERS25 functions as a regulator of the heat-shock and cell death response.
The Journal of biological chemistry283(19)13063-9(2008 May)
Hwang SO,Boswell SA,Seo JS,Lee SW