TOX4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOX4
Entrez Gene ID	9878
Full Name	TOX high mobility group box family member 4
Synonyms	C14orf92,KIAA0737,LCP1,MIG7
General protein information	Preferred Names TOX high mobility group box family member 4 Names TOX high mobility group box family member 4 epidermal Langerhans cell protein LCP1 migration-inducing protein 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q11.2
Disorder MIM:	614032

mRNA and Protein(s)

mRNA	Protein	Name
NM_001303523.2	NP_001290452.1	TOX high mobility group box family member 4 isoform 2
NM_014828.4	NP_055643.1	TOX high mobility group box family member 4 isoform 1
NM_001303523.1	NP_001290452.1	TOX high mobility group box family member 4 isoform 2
NM_014828.3	NP_055643.1	TOX high mobility group box family member 4 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TOX4	NP_055643.1
	TOX4	NP_001165884.1
Xenopus tropicalis (tropical clawed frog)	tox4	NP_001090624.1
Mus musculus (house mouse)	Tox4	NP_075923.2
Canis lupus familiaris (dog)	TOX4	XP_532626.2
Bos taurus (cattle)	TOX4	NP_001069175.1
Pan troglodytes (chimpanzee)	TOX4	XP_003314295.1
Rattus norvegicus (Norway rat)	Tox4	NP_775446.2

Gene Ontology
Bibliography

Related articles in PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM
Nature communications53650(2014 Apr)

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, Lingner J
Nature communications42848(2013)

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.
Morchikh M, Naughtin M, Di Nunzio F, Xavier J, Charneau P, Jacob Y, Lavigne M
PloS one8(11)e81217(2013)

[Mig-7 enhances vasculogenic mimicry in gastric cancer cells].
Li WL, Gao Q
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology28(11)1142-5(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a regulation of LEDGF interaction with chromatin by cellular partners of its PWWP domain could be involved in several processes linked to LEDGF tethering properties, such as lentiviral integration, DNA repair or transcriptional regulation
Title: TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

The formation of vasculogenic mimicry is inhibited by reducing the expression of Mig-7 in gastric cancer cells.
Title: [Mig-7 enhances vasculogenic mimicry in gastric cancer cells].

Compared with TOX4, expression of TOX1, TOX2 and TOX3 in normal lung was 25, 44, and 88%lower, respectively, supporting the premise that reduced promoter activity confers increased susceptibility to methylation during lung carcinogenesis.
Title: Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers.

interaction between TOX4 and platinated DNA
Title: TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs.

mammalian Wdr82 functions in a variety of cellular processes; PTW/PP1 phosphatase complex (PNUTS, Tox4, Wdr82, PP1) has a role in the regulation of chromatin structure during the transition from mitosis into interphase
Title: Identification and characterization of a novel human PP1 phosphatase complex.

The following TOX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30127	NM_014828.4 Latest version!	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu63438	NM_001303523.2 Latest version!	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu63438	NM_001303523.1	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu30127	NM_014828.3	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOX4 ( NM_014828.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055643.1 Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30127
Clone ID Related Accession (Same CDS sequence)	NM_014828.4 , NM_014828.3
Accession Version	NM_014828.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-11
Organism	Homo sapiens(human)
Product	TOX high mobility group box family member 4 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA334895.1, BC020292.1, AL161747.5 and N63399.1. On Nov 23, 2018 this sequence version replaced NM_014828.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.255590.1, SRR1803611.262124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000448790.7/ ENSP00000393080.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTTTC CCGGAGGAAA TGACAATTAC CTGACGATCA CAGGGCCTTC GCACCCCTTC 
CTGTCAGGGG CCGAGACATT CCATACACCA AGCTTGGGTG ATGAGGAATT TGAAATCCCA 
CCTATCTCCT TGGATTCTGA TCCCTCATTG GCTGTCTCAG ATGTGGTTGG CCACTTTGAT 
GACCTGGCAG ACCCTTCCTC TTCACAGGAT GGCAGTTTTT CAGCCCAGTA TGGGGTCCAG 
ACATTGGACA TGCCTGTGGG CATGACCCAT GGCTTGATGG AGCAGGGCGG GGGGCTCCTG 
AGTGGGGGCT TGACCATGGA CTTGGACCAC TCTATAGGAA CTCAGTATAG TGCCAACCCA 
CCTGTTACAA TTGATGTACC AATGACAGAC ATGACATCTG GCTTGATGGG GCATAGCCAG 
TTGACCACCA TTGATCAGTC AGAACTGAGT TCCCAGCTGG GTTTGAGCCT AGGGGGTGGC 
ACCATCCTGC CACCTGCCCA GTCACCTGAA GATCGTCTTT CAACCACCCC TTCACCTACT 
AGTTCACTTC ACGAGGATGG TGTTGAGGAT TTCCGGAGGC AACTTCCCAG CCAGAAGACA 
GTCGTGGTGG AAGCAGGGAA AAAGCAGAAG GCCCCAAAGA AGAGAAAAAA GAAAGATCCT 
AATGAACCTC AGAAACCAGT TTCAGCATAT GCTTTATTCT TTCGTGATAC ACAGGCTGCC 
ATCAAGGGAC AGAATCCTAA TGCCACTTTT GGTGAGGTTT CAAAAATTGT GGCCTCCATG 
TGGGATAGTC TTGGAGAGGA GCAAAAACAG GTATATAAGA GGAAAACTGA GGCTGCCAAG 
AAAGAGTATC TGAAGGCACT GGCTGCTTAC AAAGACAACC AGGAGTGTCA GGCCACTGTG 
GAAACAGTGG AATTGGATCC AGCACCACCA TCACAAACTC CTTCTCCACC TCCTATGGCT 
ACTGTTGACC CAGCATCTCC AGCACCAGCT TCAATAGAGC CCCCTGCCCT GTCCCCATCC 
ATTGTTGTTA ACTCCACCCT TTCATCCTAT GTGGCAAACC AGGCATCTTC TGGAGCTGGG 
GGTCAGCCCA ATATCACCAA GTTGATTATT ACCAAACAAA TGTTGCCCTC TTCTATTACT 
ATGTCTCAAG GAGGGATGGT TACTGTTATC CCAGCCACAG TGGTGACCTC CCGGGGGCTC 
CAACTAGGCC AAACCAGTAC AGCTACTATC CAGCCCAGTC AACAAGCCCA GATTGTCACT 
CGGTCAGTGT TGCAGGCAGC AGCAGCTGCT GCTGCTGCTG CTTCTATGCA ACTGCCTCCA 
CCCCGACTAC AGCCCCCTCC ATTACAACAG ATGCCACAGC CCCCGACTCA GCAGCAAGTT 
ACCATTCTGC AGCAGCCTCC TCCACTCCAG GCCATGCAAC AGCCTCCACC TCAGAAAGTT 
CGAATCAATT TACAGCAACA GCCTCCTCCT CTGCAGATCA AGAGTGTGCC TCTACCCACT 
TTGAAAATGC AGACTACCTT AGTCCCACCA ACTGTGGAAA GTAGTCCTGA GCGGCCTATG 
AACAACAGCC CTGAGGCCCA TACAGTGGAG GCACCTTCTC CTGAGACTAT CTGTGAGATG 
ATCACAGATG TAGTTCCTGA GGTTGAGTCT CCTTCTCAGA TGGATGTTGA ATTGGTGAGT 
GGGTCTCCTG TGGCACTCTC ACCCCAGCCT CGATGTGTGA GGTCTGGTTG TGAGAACCCT 
CCCATTGTGA GTAAGGACTG GGACAATGAA TACTGCAGCA ATGAGTGTGT GGTGAAGCAC 
TGCAGGGATG TATTCTTGGC CTGGGTAGCC TCTAGAAATT CAAACACAGT GGTGTTTGTG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055643.1
CDS	85..1950
Translation	MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK

Target ORF information:

RefSeq Version	NM_014828.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014828.4

ORF Insert Sequence:

ATGGAGTTTC CCGGAGGAAA TGACAATTAC CTGACGATCA CAGGGCCTTC GCACCCCTTC 
CTGTCAGGGG CCGAGACATT CCATACACCA AGCTTGGGTG ATGAGGAATT TGAAATCCCA 
CCTATCTCCT TGGATTCTGA TCCCTCATTG GCTGTCTCAG ATGTGGTTGG CCACTTTGAT 
GACCTGGCAG ACCCTTCCTC TTCACAGGAT GGCAGTTTTT CAGCCCAGTA TGGGGTCCAG 
ACATTGGACA TGCCTGTGGG CATGACCCAT GGCTTGATGG AGCAGGGCGG GGGGCTCCTG 
AGTGGGGGCT TGACCATGGA CTTGGACCAC TCTATAGGAA CTCAGTATAG TGCCAACCCA 
CCTGTTACAA TTGATGTACC AATGACAGAC ATGACATCTG GCTTGATGGG GCATAGCCAG 
TTGACCACCA TTGATCAGTC AGAACTGAGT TCCCAGCTGG GTTTGAGCCT AGGGGGTGGC 
ACCATCCTGC CACCTGCCCA GTCACCTGAA GATCGTCTTT CAACCACCCC TTCACCTACT 
AGTTCACTTC ACGAGGATGG TGTTGAGGAT TTCCGGAGGC AACTTCCCAG CCAGAAGACA 
GTCGTGGTGG AAGCAGGGAA AAAGCAGAAG GCCCCAAAGA AGAGAAAAAA GAAAGATCCT 
AATGAACCTC AGAAACCAGT TTCAGCATAT GCTTTATTCT TTCGTGATAC ACAGGCTGCC 
ATCAAGGGAC AGAATCCTAA TGCCACTTTT GGTGAGGTTT CAAAAATTGT GGCCTCCATG 
TGGGATAGTC TTGGAGAGGA GCAAAAACAG GTATATAAGA GGAAAACTGA GGCTGCCAAG 
AAAGAGTATC TGAAGGCACT GGCTGCTTAC AAAGACAACC AGGAGTGTCA GGCCACTGTG 
GAAACAGTGG AATTGGATCC AGCACCACCA TCACAAACTC CTTCTCCACC TCCTATGGCT 
ACTGTTGACC CAGCATCTCC AGCACCAGCT TCAATAGAGC CCCCTGCCCT GTCCCCATCC 
ATTGTTGTTA ACTCCACCCT TTCATCCTAT GTGGCAAACC AGGCATCTTC TGGAGCTGGG 
GGTCAGCCCA ATATCACCAA GTTGATTATT ACCAAACAAA TGTTGCCCTC TTCTATTACT 
ATGTCTCAAG GAGGGATGGT TACTGTTATC CCAGCCACAG TGGTGACCTC CCGGGGGCTC 
CAACTAGGCC AAACCAGTAC AGCTACTATC CAGCCCAGTC AACAAGCCCA GATTGTCACT 
CGGTCAGTGT TGCAGGCAGC AGCAGCTGCT GCTGCTGCTG CTTCTATGCA ACTGCCTCCA 
CCCCGACTAC AGCCCCCTCC ATTACAACAG ATGCCACAGC CCCCGACTCA GCAGCAAGTT 
ACCATTCTGC AGCAGCCTCC TCCACTCCAG GCCATGCAAC AGCCTCCACC TCAGAAAGTT 
CGAATCAATT TACAGCAACA GCCTCCTCCT CTGCAGATCA AGAGTGTGCC TCTACCCACT 
TTGAAAATGC AGACTACCTT AGTCCCACCA ACTGTGGAAA GTAGTCCTGA GCGGCCTATG 
AACAACAGCC CTGAGGCCCA TACAGTGGAG GCACCTTCTC CTGAGACTAT CTGTGAGATG 
ATCACAGATG TAGTTCCTGA GGTTGAGTCT CCTTCTCAGA TGGATGTTGA ATTGGTGAGT 
GGGTCTCCTG TGGCACTCTC ACCCCAGCCT CGATGTGTGA GGTCTGGTTG TGAGAACCCT 
CCCATTGTGA GTAAGGACTG GGACAATGAA TACTGCAGCA ATGAGTGTGT GGTGAAGCAC 
TGCAGGGATG TATTCTTGGC CTGGGTAGCC TCTAGAAATT CAAACACAGT GGTGTTTGTG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOX4 ( NM_014828.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055643.1 Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30127
Clone ID Related Accession (Same CDS sequence)	NM_014828.4 , NM_014828.3
Accession Version	NM_014828.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	TOX high mobility group box family member 4 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA334895.1, BC020292.1, AL161747.5 and N63399.1. On Jan 8, 2015 this sequence version replaced NM_014828.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.86633.1, SRR1803611.262124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTTC CCGGAGGAAA TGACAATTAC CTGACGATCA CAGGGCCTTC GCACCCCTTC 
CTGTCAGGGG CCGAGACATT CCATACACCA AGCTTGGGTG ATGAGGAATT TGAAATCCCA 
CCTATCTCCT TGGATTCTGA TCCCTCATTG GCTGTCTCAG ATGTGGTTGG CCACTTTGAT 
GACCTGGCAG ACCCTTCCTC TTCACAGGAT GGCAGTTTTT CAGCCCAGTA TGGGGTCCAG 
ACATTGGACA TGCCTGTGGG CATGACCCAT GGCTTGATGG AGCAGGGCGG GGGGCTCCTG 
AGTGGGGGCT TGACCATGGA CTTGGACCAC TCTATAGGAA CTCAGTATAG TGCCAACCCA 
CCTGTTACAA TTGATGTACC AATGACAGAC ATGACATCTG GCTTGATGGG GCATAGCCAG 
TTGACCACCA TTGATCAGTC AGAACTGAGT TCCCAGCTGG GTTTGAGCCT AGGGGGTGGC 
ACCATCCTGC CACCTGCCCA GTCACCTGAA GATCGTCTTT CAACCACCCC TTCACCTACT 
AGTTCACTTC ACGAGGATGG TGTTGAGGAT TTCCGGAGGC AACTTCCCAG CCAGAAGACA 
GTCGTGGTGG AAGCAGGGAA AAAGCAGAAG GCCCCAAAGA AGAGAAAAAA GAAAGATCCT 
AATGAACCTC AGAAACCAGT TTCAGCATAT GCTTTATTCT TTCGTGATAC ACAGGCTGCC 
ATCAAGGGAC AGAATCCTAA TGCCACTTTT GGTGAGGTTT CAAAAATTGT GGCCTCCATG 
TGGGATAGTC TTGGAGAGGA GCAAAAACAG GTATATAAGA GGAAAACTGA GGCTGCCAAG 
AAAGAGTATC TGAAGGCACT GGCTGCTTAC AAAGACAACC AGGAGTGTCA GGCCACTGTG 
GAAACAGTGG AATTGGATCC AGCACCACCA TCACAAACTC CTTCTCCACC TCCTATGGCT 
ACTGTTGACC CAGCATCTCC AGCACCAGCT TCAATAGAGC CCCCTGCCCT GTCCCCATCC 
ATTGTTGTTA ACTCCACCCT TTCATCCTAT GTGGCAAACC AGGCATCTTC TGGAGCTGGG 
GGTCAGCCCA ATATCACCAA GTTGATTATT ACCAAACAAA TGTTGCCCTC TTCTATTACT 
ATGTCTCAAG GAGGGATGGT TACTGTTATC CCAGCCACAG TGGTGACCTC CCGGGGGCTC 
CAACTAGGCC AAACCAGTAC AGCTACTATC CAGCCCAGTC AACAAGCCCA GATTGTCACT 
CGGTCAGTGT TGCAGGCAGC AGCAGCTGCT GCTGCTGCTG CTTCTATGCA ACTGCCTCCA 
CCCCGACTAC AGCCCCCTCC ATTACAACAG ATGCCACAGC CCCCGACTCA GCAGCAAGTT 
ACCATTCTGC AGCAGCCTCC TCCACTCCAG GCCATGCAAC AGCCTCCACC TCAGAAAGTT 
CGAATCAATT TACAGCAACA GCCTCCTCCT CTGCAGATCA AGAGTGTGCC TCTACCCACT 
TTGAAAATGC AGACTACCTT AGTCCCACCA ACTGTGGAAA GTAGTCCTGA GCGGCCTATG 
AACAACAGCC CTGAGGCCCA TACAGTGGAG GCACCTTCTC CTGAGACTAT CTGTGAGATG 
ATCACAGATG TAGTTCCTGA GGTTGAGTCT CCTTCTCAGA TGGATGTTGA ATTGGTGAGT 
GGGTCTCCTG TGGCACTCTC ACCCCAGCCT CGATGTGTGA GGTCTGGTTG TGAGAACCCT 
CCCATTGTGA GTAAGGACTG GGACAATGAA TACTGCAGCA ATGAGTGTGT GGTGAAGCAC 
TGCAGGGATG TATTCTTGGC CTGGGTAGCC TCTAGAAATT CAAACACAGT GGTGTTTGTG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055643.1
CDS	104..1969
Translation	MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK

Target ORF information:

RefSeq Version	NM_014828.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014828.3

ORF Insert Sequence:

ATGGAGTTTC CCGGAGGAAA TGACAATTAC CTGACGATCA CAGGGCCTTC GCACCCCTTC 
CTGTCAGGGG CCGAGACATT CCATACACCA AGCTTGGGTG ATGAGGAATT TGAAATCCCA 
CCTATCTCCT TGGATTCTGA TCCCTCATTG GCTGTCTCAG ATGTGGTTGG CCACTTTGAT 
GACCTGGCAG ACCCTTCCTC TTCACAGGAT GGCAGTTTTT CAGCCCAGTA TGGGGTCCAG 
ACATTGGACA TGCCTGTGGG CATGACCCAT GGCTTGATGG AGCAGGGCGG GGGGCTCCTG 
AGTGGGGGCT TGACCATGGA CTTGGACCAC TCTATAGGAA CTCAGTATAG TGCCAACCCA 
CCTGTTACAA TTGATGTACC AATGACAGAC ATGACATCTG GCTTGATGGG GCATAGCCAG 
TTGACCACCA TTGATCAGTC AGAACTGAGT TCCCAGCTGG GTTTGAGCCT AGGGGGTGGC 
ACCATCCTGC CACCTGCCCA GTCACCTGAA GATCGTCTTT CAACCACCCC TTCACCTACT 
AGTTCACTTC ACGAGGATGG TGTTGAGGAT TTCCGGAGGC AACTTCCCAG CCAGAAGACA 
GTCGTGGTGG AAGCAGGGAA AAAGCAGAAG GCCCCAAAGA AGAGAAAAAA GAAAGATCCT 
AATGAACCTC AGAAACCAGT TTCAGCATAT GCTTTATTCT TTCGTGATAC ACAGGCTGCC 
ATCAAGGGAC AGAATCCTAA TGCCACTTTT GGTGAGGTTT CAAAAATTGT GGCCTCCATG 
TGGGATAGTC TTGGAGAGGA GCAAAAACAG GTATATAAGA GGAAAACTGA GGCTGCCAAG 
AAAGAGTATC TGAAGGCACT GGCTGCTTAC AAAGACAACC AGGAGTGTCA GGCCACTGTG 
GAAACAGTGG AATTGGATCC AGCACCACCA TCACAAACTC CTTCTCCACC TCCTATGGCT 
ACTGTTGACC CAGCATCTCC AGCACCAGCT TCAATAGAGC CCCCTGCCCT GTCCCCATCC 
ATTGTTGTTA ACTCCACCCT TTCATCCTAT GTGGCAAACC AGGCATCTTC TGGAGCTGGG 
GGTCAGCCCA ATATCACCAA GTTGATTATT ACCAAACAAA TGTTGCCCTC TTCTATTACT 
ATGTCTCAAG GAGGGATGGT TACTGTTATC CCAGCCACAG TGGTGACCTC CCGGGGGCTC 
CAACTAGGCC AAACCAGTAC AGCTACTATC CAGCCCAGTC AACAAGCCCA GATTGTCACT 
CGGTCAGTGT TGCAGGCAGC AGCAGCTGCT GCTGCTGCTG CTTCTATGCA ACTGCCTCCA 
CCCCGACTAC AGCCCCCTCC ATTACAACAG ATGCCACAGC CCCCGACTCA GCAGCAAGTT 
ACCATTCTGC AGCAGCCTCC TCCACTCCAG GCCATGCAAC AGCCTCCACC TCAGAAAGTT 
CGAATCAATT TACAGCAACA GCCTCCTCCT CTGCAGATCA AGAGTGTGCC TCTACCCACT 
TTGAAAATGC AGACTACCTT AGTCCCACCA ACTGTGGAAA GTAGTCCTGA GCGGCCTATG 
AACAACAGCC CTGAGGCCCA TACAGTGGAG GCACCTTCTC CTGAGACTAT CTGTGAGATG 
ATCACAGATG TAGTTCCTGA GGTTGAGTCT CCTTCTCAGA TGGATGTTGA ATTGGTGAGT 
GGGTCTCCTG TGGCACTCTC ACCCCAGCCT CGATGTGTGA GGTCTGGTTG TGAGAACCCT 
CCCATTGTGA GTAAGGACTG GGACAATGAA TACTGCAGCA ATGAGTGTGT GGTGAAGCAC 
TGCAGGGATG TATTCTTGGC CTGGGTAGCC TCTAGAAATT CAAACACAGT GGTGTTTGTG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOX4 ( NM_001303523.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290452.1 Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu63438
Clone ID Related Accession (Same CDS sequence)	NM_001303523.2 , NM_001303523.1
Accession Version	NM_001303523.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-11
Organism	Homo sapiens(human)
Product	TOX high mobility group box family member 4 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA334895.1, AK298555.1, BC020292.1, AL161747.5 and N63399.1. On May 31, 2019 this sequence version replaced NM_001303523.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298555.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162823, SAMEA2163105 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACAT TCCATACACC AAGCTTGGGT GATGAGGAAT TTGAAATCCC ACCTATCTCC 
TTGGATTCTG ATCCCTCATT GGCTGTCTCA GATGTGGTTG GCCACTTTGA TGACCTGGCA 
GACCCTTCCT CTTCACAGGA TGGCAGTTTT TCAGCCCAGT ATGGGGTCCA GACATTGGAC 
ATGCCTGTGG GCATGACCCA TGGCTTGATG GAGCAGGGCG GGGGGCTCCT GAGTGGGGGC 
TTGACCATGG ACTTGGACCA CTCTATAGGA ACTCAGTATA GTGCCAACCC ACCTGTTACA 
ATTGATGTAC CAATGACAGA CATGACATCT GGCTTGATGG GGCATAGCCA GTTGACCACC 
ATTGATCAGT CAGAACTGAG TTCCCAGCTG GGTTTGAGCC TAGGGGGTGG CACCATCCTG 
CCACCTGCCC AGTCACCTGA AGATCGTCTT TCAACCACCC CTTCACCTAC TAGTTCACTT 
CACGAGGATG GTGTTGAGGA TTTCCGGAGG CAACTTCCCA GCCAGAAGAC AGTCGTGGTG 
GAAGCAGGGA AAAAGCAGAA GGCCCCAAAG AAGAGAAAAA AGAAAGATCC TAATGAACCT 
CAGAAACCAG TTTCAGCATA TGCTTTATTC TTTCGTGATA CACAGGCTGC CATCAAGGGA 
CAGAATCCTA ATGCCACTTT TGGTGAGGTT TCAAAAATTG TGGCCTCCAT GTGGGATAGT 
CTTGGAGAGG AGCAAAAACA GGTATATAAG AGGAAAACTG AGGCTGCCAA GAAAGAGTAT 
CTGAAGGCAC TGGCTGCTTA CAAAGACAAC CAGGAGTGTC AGGCCACTGT GGAAACAGTG 
GAATTGGATC CAGCACCACC ATCACAAACT CCTTCTCCAC CTCCTATGGC TACTGTTGAC 
CCAGCATCTC CAGCACCAGC TTCAATAGAG CCCCCTGCCC TGTCCCCATC CATTGTTGTT 
AACTCCACCC TTTCATCCTA TGTGGCAAAC CAGGCATCTT CTGGAGCTGG GGGTCAGCCC 
AATATCACCA AGTTGATTAT TACCAAACAA ATGTTGCCCT CTTCTATTAC TATGTCTCAA 
GGAGGGATGG TTACTGTTAT CCCAGCCACA GTGGTGACCT CCCGGGGGCT CCAACTAGGC 
CAAACCAGTA CAGCTACTAT CCAGCCCAGT CAACAAGCCC AGATTGTCAC TCGGTCAGTG 
TTGCAGGCAG CAGCAGCTGC TGCTGCTGCT GCTTCTATGC AACTGCCTCC ACCCCGACTA 
CAGCCCCCTC CATTACAACA GATGCCACAG CCCCCGACTC AGCAGCAAGT TACCATTCTG 
CAGCAGCCTC CTCCACTCCA GGCCATGCAA CAGCCTCCAC CTCAGAAAGT TCGAATCAAT 
TTACAGCAAC AGCCTCCTCC TCTGCAGATC AAGAGTGTGC CTCTACCCAC TTTGAAAATG 
CAGACTACCT TAGTCCCACC AACTGTGGAA AGTAGTCCTG AGCGGCCTAT GAACAACAGC 
CCTGAGGCCC ATACAGTGGA GGCACCTTCT CCTGAGACTA TCTGTGAGAT GATCACAGAT 
GTAGTTCCTG AGGTTGAGTC TCCTTCTCAG ATGGATGTTG AATTGGTGAG TGGGTCTCCT 
GTGGCACTCT CACCCCAGCC TCGATGTGTG AGGTCTGGTT GTGAGAACCC TCCCATTGTG 
AGTAAGGACT GGGACAATGA ATACTGCAGC AATGAGTGTG TGGTGAAGCA CTGCAGGGAT 
GTATTCTTGG CCTGGGTAGC CTCTAGAAAT TCAAACACAG TGGTGTTTGT GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290452.1
CDS	85..1881
Translation	METFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK

Target ORF information:

RefSeq Version	NM_001303523.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303523.2

ORF Insert Sequence:

ATGGAGACAT TCCATACACC AAGCTTGGGT GATGAGGAAT TTGAAATCCC ACCTATCTCC 
TTGGATTCTG ATCCCTCATT GGCTGTCTCA GATGTGGTTG GCCACTTTGA TGACCTGGCA 
GACCCTTCCT CTTCACAGGA TGGCAGTTTT TCAGCCCAGT ATGGGGTCCA GACATTGGAC 
ATGCCTGTGG GCATGACCCA TGGCTTGATG GAGCAGGGCG GGGGGCTCCT GAGTGGGGGC 
TTGACCATGG ACTTGGACCA CTCTATAGGA ACTCAGTATA GTGCCAACCC ACCTGTTACA 
ATTGATGTAC CAATGACAGA CATGACATCT GGCTTGATGG GGCATAGCCA GTTGACCACC 
ATTGATCAGT CAGAACTGAG TTCCCAGCTG GGTTTGAGCC TAGGGGGTGG CACCATCCTG 
CCACCTGCCC AGTCACCTGA AGATCGTCTT TCAACCACCC CTTCACCTAC TAGTTCACTT 
CACGAGGATG GTGTTGAGGA TTTCCGGAGG CAACTTCCCA GCCAGAAGAC AGTCGTGGTG 
GAAGCAGGGA AAAAGCAGAA GGCCCCAAAG AAGAGAAAAA AGAAAGATCC TAATGAACCT 
CAGAAACCAG TTTCAGCATA TGCTTTATTC TTTCGTGATA CACAGGCTGC CATCAAGGGA 
CAGAATCCTA ATGCCACTTT TGGTGAGGTT TCAAAAATTG TGGCCTCCAT GTGGGATAGT 
CTTGGAGAGG AGCAAAAACA GGTATATAAG AGGAAAACTG AGGCTGCCAA GAAAGAGTAT 
CTGAAGGCAC TGGCTGCTTA CAAAGACAAC CAGGAGTGTC AGGCCACTGT GGAAACAGTG 
GAATTGGATC CAGCACCACC ATCACAAACT CCTTCTCCAC CTCCTATGGC TACTGTTGAC 
CCAGCATCTC CAGCACCAGC TTCAATAGAG CCCCCTGCCC TGTCCCCATC CATTGTTGTT 
AACTCCACCC TTTCATCCTA TGTGGCAAAC CAGGCATCTT CTGGAGCTGG GGGTCAGCCC 
AATATCACCA AGTTGATTAT TACCAAACAA ATGTTGCCCT CTTCTATTAC TATGTCTCAA 
GGAGGGATGG TTACTGTTAT CCCAGCCACA GTGGTGACCT CCCGGGGGCT CCAACTAGGC 
CAAACCAGTA CAGCTACTAT CCAGCCCAGT CAACAAGCCC AGATTGTCAC TCGGTCAGTG 
TTGCAGGCAG CAGCAGCTGC TGCTGCTGCT GCTTCTATGC AACTGCCTCC ACCCCGACTA 
CAGCCCCCTC CATTACAACA GATGCCACAG CCCCCGACTC AGCAGCAAGT TACCATTCTG 
CAGCAGCCTC CTCCACTCCA GGCCATGCAA CAGCCTCCAC CTCAGAAAGT TCGAATCAAT 
TTACAGCAAC AGCCTCCTCC TCTGCAGATC AAGAGTGTGC CTCTACCCAC TTTGAAAATG 
CAGACTACCT TAGTCCCACC AACTGTGGAA AGTAGTCCTG AGCGGCCTAT GAACAACAGC 
CCTGAGGCCC ATACAGTGGA GGCACCTTCT CCTGAGACTA TCTGTGAGAT GATCACAGAT 
GTAGTTCCTG AGGTTGAGTC TCCTTCTCAG ATGGATGTTG AATTGGTGAG TGGGTCTCCT 
GTGGCACTCT CACCCCAGCC TCGATGTGTG AGGTCTGGTT GTGAGAACCC TCCCATTGTG 
AGTAAGGACT GGGACAATGA ATACTGCAGC AATGAGTGTG TGGTGAAGCA CTGCAGGGAT 
GTATTCTTGG CCTGGGTAGC CTCTAGAAAT TCAAACACAG TGGTGTTTGT GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOX4 ( NM_001303523.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290452.1 Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.

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CloneID	OHu63438
Clone ID Related Accession (Same CDS sequence)	NM_001303523.2 , NM_001303523.1
Accession Version	NM_001303523.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	TOX high mobility group box family member 4 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA334895.1, AK298555.1, BC020292.1, AL161747.5 and N63399.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298555.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162823, SAMEA2163105 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACAT TCCATACACC AAGCTTGGGT GATGAGGAAT TTGAAATCCC ACCTATCTCC 
TTGGATTCTG ATCCCTCATT GGCTGTCTCA GATGTGGTTG GCCACTTTGA TGACCTGGCA 
GACCCTTCCT CTTCACAGGA TGGCAGTTTT TCAGCCCAGT ATGGGGTCCA GACATTGGAC 
ATGCCTGTGG GCATGACCCA TGGCTTGATG GAGCAGGGCG GGGGGCTCCT GAGTGGGGGC 
TTGACCATGG ACTTGGACCA CTCTATAGGA ACTCAGTATA GTGCCAACCC ACCTGTTACA 
ATTGATGTAC CAATGACAGA CATGACATCT GGCTTGATGG GGCATAGCCA GTTGACCACC 
ATTGATCAGT CAGAACTGAG TTCCCAGCTG GGTTTGAGCC TAGGGGGTGG CACCATCCTG 
CCACCTGCCC AGTCACCTGA AGATCGTCTT TCAACCACCC CTTCACCTAC TAGTTCACTT 
CACGAGGATG GTGTTGAGGA TTTCCGGAGG CAACTTCCCA GCCAGAAGAC AGTCGTGGTG 
GAAGCAGGGA AAAAGCAGAA GGCCCCAAAG AAGAGAAAAA AGAAAGATCC TAATGAACCT 
CAGAAACCAG TTTCAGCATA TGCTTTATTC TTTCGTGATA CACAGGCTGC CATCAAGGGA 
CAGAATCCTA ATGCCACTTT TGGTGAGGTT TCAAAAATTG TGGCCTCCAT GTGGGATAGT 
CTTGGAGAGG AGCAAAAACA GGTATATAAG AGGAAAACTG AGGCTGCCAA GAAAGAGTAT 
CTGAAGGCAC TGGCTGCTTA CAAAGACAAC CAGGAGTGTC AGGCCACTGT GGAAACAGTG 
GAATTGGATC CAGCACCACC ATCACAAACT CCTTCTCCAC CTCCTATGGC TACTGTTGAC 
CCAGCATCTC CAGCACCAGC TTCAATAGAG CCCCCTGCCC TGTCCCCATC CATTGTTGTT 
AACTCCACCC TTTCATCCTA TGTGGCAAAC CAGGCATCTT CTGGAGCTGG GGGTCAGCCC 
AATATCACCA AGTTGATTAT TACCAAACAA ATGTTGCCCT CTTCTATTAC TATGTCTCAA 
GGAGGGATGG TTACTGTTAT CCCAGCCACA GTGGTGACCT CCCGGGGGCT CCAACTAGGC 
CAAACCAGTA CAGCTACTAT CCAGCCCAGT CAACAAGCCC AGATTGTCAC TCGGTCAGTG 
TTGCAGGCAG CAGCAGCTGC TGCTGCTGCT GCTTCTATGC AACTGCCTCC ACCCCGACTA 
CAGCCCCCTC CATTACAACA GATGCCACAG CCCCCGACTC AGCAGCAAGT TACCATTCTG 
CAGCAGCCTC CTCCACTCCA GGCCATGCAA CAGCCTCCAC CTCAGAAAGT TCGAATCAAT 
TTACAGCAAC AGCCTCCTCC TCTGCAGATC AAGAGTGTGC CTCTACCCAC TTTGAAAATG 
CAGACTACCT TAGTCCCACC AACTGTGGAA AGTAGTCCTG AGCGGCCTAT GAACAACAGC 
CCTGAGGCCC ATACAGTGGA GGCACCTTCT CCTGAGACTA TCTGTGAGAT GATCACAGAT 
GTAGTTCCTG AGGTTGAGTC TCCTTCTCAG ATGGATGTTG AATTGGTGAG TGGGTCTCCT 
GTGGCACTCT CACCCCAGCC TCGATGTGTG AGGTCTGGTT GTGAGAACCC TCCCATTGTG 
AGTAAGGACT GGGACAATGA ATACTGCAGC AATGAGTGTG TGGTGAAGCA CTGCAGGGAT 
GTATTCTTGG CCTGGGTAGC CTCTAGAAAT TCAAACACAG TGGTGTTTGT GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290452.1
CDS	104..1900
Translation	METFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK

Target ORF information:

RefSeq Version	NM_001303523.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TOX high mobility group box family member 4 (TOX4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303523.1

ORF Insert Sequence:

ATGGAGACAT TCCATACACC AAGCTTGGGT GATGAGGAAT TTGAAATCCC ACCTATCTCC 
TTGGATTCTG ATCCCTCATT GGCTGTCTCA GATGTGGTTG GCCACTTTGA TGACCTGGCA 
GACCCTTCCT CTTCACAGGA TGGCAGTTTT TCAGCCCAGT ATGGGGTCCA GACATTGGAC 
ATGCCTGTGG GCATGACCCA TGGCTTGATG GAGCAGGGCG GGGGGCTCCT GAGTGGGGGC 
TTGACCATGG ACTTGGACCA CTCTATAGGA ACTCAGTATA GTGCCAACCC ACCTGTTACA 
ATTGATGTAC CAATGACAGA CATGACATCT GGCTTGATGG GGCATAGCCA GTTGACCACC 
ATTGATCAGT CAGAACTGAG TTCCCAGCTG GGTTTGAGCC TAGGGGGTGG CACCATCCTG 
CCACCTGCCC AGTCACCTGA AGATCGTCTT TCAACCACCC CTTCACCTAC TAGTTCACTT 
CACGAGGATG GTGTTGAGGA TTTCCGGAGG CAACTTCCCA GCCAGAAGAC AGTCGTGGTG 
GAAGCAGGGA AAAAGCAGAA GGCCCCAAAG AAGAGAAAAA AGAAAGATCC TAATGAACCT 
CAGAAACCAG TTTCAGCATA TGCTTTATTC TTTCGTGATA CACAGGCTGC CATCAAGGGA 
CAGAATCCTA ATGCCACTTT TGGTGAGGTT TCAAAAATTG TGGCCTCCAT GTGGGATAGT 
CTTGGAGAGG AGCAAAAACA GGTATATAAG AGGAAAACTG AGGCTGCCAA GAAAGAGTAT 
CTGAAGGCAC TGGCTGCTTA CAAAGACAAC CAGGAGTGTC AGGCCACTGT GGAAACAGTG 
GAATTGGATC CAGCACCACC ATCACAAACT CCTTCTCCAC CTCCTATGGC TACTGTTGAC 
CCAGCATCTC CAGCACCAGC TTCAATAGAG CCCCCTGCCC TGTCCCCATC CATTGTTGTT 
AACTCCACCC TTTCATCCTA TGTGGCAAAC CAGGCATCTT CTGGAGCTGG GGGTCAGCCC 
AATATCACCA AGTTGATTAT TACCAAACAA ATGTTGCCCT CTTCTATTAC TATGTCTCAA 
GGAGGGATGG TTACTGTTAT CCCAGCCACA GTGGTGACCT CCCGGGGGCT CCAACTAGGC 
CAAACCAGTA CAGCTACTAT CCAGCCCAGT CAACAAGCCC AGATTGTCAC TCGGTCAGTG 
TTGCAGGCAG CAGCAGCTGC TGCTGCTGCT GCTTCTATGC AACTGCCTCC ACCCCGACTA 
CAGCCCCCTC CATTACAACA GATGCCACAG CCCCCGACTC AGCAGCAAGT TACCATTCTG 
CAGCAGCCTC CTCCACTCCA GGCCATGCAA CAGCCTCCAC CTCAGAAAGT TCGAATCAAT 
TTACAGCAAC AGCCTCCTCC TCTGCAGATC AAGAGTGTGC CTCTACCCAC TTTGAAAATG 
CAGACTACCT TAGTCCCACC AACTGTGGAA AGTAGTCCTG AGCGGCCTAT GAACAACAGC 
CCTGAGGCCC ATACAGTGGA GGCACCTTCT CCTGAGACTA TCTGTGAGAT GATCACAGAT 
GTAGTTCCTG AGGTTGAGTC TCCTTCTCAG ATGGATGTTG AATTGGTGAG TGGGTCTCCT 
GTGGCACTCT CACCCCAGCC TCGATGTGTG AGGTCTGGTT GTGAGAACCC TCCCATTGTG 
AGTAAGGACT GGGACAATGA ATACTGCAGC AATGAGTGTG TGGTGAAGCA CTGCAGGGAT 
GTATTCTTGG CCTGGGTAGC CTCTAGAAAT TCAAACACAG TGGTGTTTGT GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Nature communications53650(2014 Apr)
Corominas R,Yang X,Lin GN,Kang S,Shen Y,Ghamsari L,Broly M,Rodriguez M,Tam S,Trigg SA,Fan C,Yi S,Tasan M,Lemmens I,Kuang X,Zhao N,Malhotra D,Michaelson JJ,Vacic V,Calderwood MA,Roth FP,Tavernier J,Horvath S,Salehi-Ashtiani K,Korkin D,Sebat J,Hill DE,Hao T,Vidal M,Iakoucheva LM

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Nature communications42848(2013)
Grolimund L,Aeby E,Hamelin R,Armand F,Chiappe D,Moniatte M,Lingner J

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.
PloS one8(11)e81217(2013)
Morchikh M,Naughtin M,Di Nunzio F,Xavier J,Charneau P,Jacob Y,Lavigne M

[Mig-7 enhances vasculogenic mimicry in gastric cancer cells].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology28(11)1142-5(2012 Nov)
Li WL,Gao Q

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TOX4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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電話

FAX

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