GPR52 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPR52
Entrez Gene ID	9293
Full Name	G protein-coupled receptor 52
General protein information	Preferred Names G protein-coupled receptor 52 Names G-protein coupled receptor 52 probable G-protein coupled receptor 52
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q25.1
Summary	Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM, Jul 2002].
Disorder MIM:	604106

mRNA and Protein(s)

mRNA	Protein	Name
NM_005684.5	NP_005675.3	G-protein coupled receptor 52
NM_005684.4	NP_005675.3	G-protein coupled receptor 52

Pathways from BioSystems

Homologies

	GPR52	XP_001104167.1
Drosophila melanogaster (fruit fly)	DopEcR	NP_001014559.1
Anopheles gambiae (African malaria mosquito)	GPRNNA21	XP_315694.1
Xenopus tropicalis (tropical clawed frog)	gpr52	XP_002931480.1
Canis lupus familiaris (dog)	GPR52	XP_005622560.1
Danio rerio (zebrafish)	LOC101884270	XP_005170560.1
Homo sapiens (human)	GPR52	NP_005675.3
Bos taurus (cattle)	GPR52	NP_001093774.1
Gallus gallus (chicken)	GPR52	XP_004943322.1
Pan troglodytes (chimpanzee)	GPR52	XP_514013.1
Mus musculus (house mouse)	Gpr52	NP_001139802.1

Gene Ontology
Bibliography

Related articles in PubMed

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.
Yao Y, Cui X, Al-Ramahi I, Sun X, Li B, Hou J, Difiglia M, Palacino J, Wu ZY, Ma L, Botas J, Lu B
eLife4(2015 Mar)

Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.
Komatsu H, Maruyama M, Yao S, Shinohara T, Sakuma K, Imaichi S, Chikatsu T, Kuniyeda K, Siu FK, Peng LS, Zhuo K, Mun LS, Han TM, Matsumoto Y, Hashimoto T, Miyajima N, Itoh Y, Ogi K, Habata Y, Mori M
PloS one9(2)e90134(2014)

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.
Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF
Brain research. Molecular brain research64(2)193-8(1999 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that G protein-coupled receptor 52 (Gpr52) modulates huntingtin protein (Htt) levels in the striatal cells in vitro and in vivo.
Title: A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.

The following GPR52 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR52 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30665	NM_005684.5 Latest version!	Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu30665	NM_005684.4	Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPR52 ( NM_005684.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005675.3 Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.

Price & Availability↑

CloneID	OHu30665
Clone ID Related Accession (Same CDS sequence)	NM_005684.5 , NM_005684.4
Accession Version	NM_005684.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	G-protein coupled receptor 52
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL022171.1, BC095532.1, BC069460.1, DA174341.1 and DB168074.1. On May 17, 2019 this sequence version replaced NM_005684.4. ##Evidence-Data-START## Transcript is intronless :: BC095532.1, SRR1803612.270767.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367685.5/ ENSP00000356658.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAATGAAT CCAGGTGGAC TGAATGGAGG ATCCTGAACA TGAGCAGTGG CATTGTGAAT 
GTGTCCGAGC GTCACTCCTG CCCACTTGGA TTTGGCCACT ACAGTGTGGT GGATGTCTGC 
ATCTTCGAGA CAGTGGTTAT TGTGTTGCTG ACATTTCTGA TCATTGCTGG GAATCTAACA 
GTTATCTTTG TCTTTCATTG TGCTCCACTG TTACATCATT ATACTACCAG CTATTTCATT 
CAGACGATGG CATATGCTGA TCTTTTCGTT GGAGTTAGCT GCTTGGTTCC TACTCTGTCA 
CTTCTCCACT ACTCCACAGG TGTCCACGAG TCATTGACTT GCCAGGTTTT TGGATATATC 
ATCTCAGTTC TAAAAAGTGT TTCTATGGCA TGTCTTGCTT GCATCAGTGT GGATCGTTAT 
CTTGCAATAA CCAAGCCTCT TTCCTACAAT CAACTGGTCA CCCCTTGTCG CTTGAGAATT 
TGCATTATTT TGATCTGGAT CTACTCCTGC CTAATTTTCT TGCCTTCCTT TTTTGGCTGG 
GGGAAACCTG GTTACCATGG TGACATTTTT GAATGGTGTG CCACGTCTTG GCTCACCAGT 
GCCTATTTTA CTGGCTTTAT TGTTTGTTTA CTTTATGCTC CTGCTGCCTT TGTTGTCTGC 
TTCACTTACT TCCACATTTT CAAAATTTGC CGTCAGCACA CCAAAGAGAT AAATGACCGA 
AGAGCCCGAT TCCCTAGTCA TGAGGTAGAT TCTTCCAGAG AGACTGGACA CAGCCCTGAC 
CGTCGCTACG CCATGGTTTT GTTTAGGATA ACCAGTGTAT TTTATATGCT GTGGCTCCCC 
TATATAATTT ACTTTCTTCT AGAAAGCTCC CGGGTCTTGG ACAATCCAAC TCTGTCCTTC 
TTAACAACCT GGCTTGCAAT AAGTAATAGT TTTTGTAACT GTGTAATATA CAGCCTCTCC 
AACAGCGTTT TCCGGCTAGG CCTCCGAAGA CTGTCTGAGA CAATGTGCAC ATCCTGTATG 
TGTGTGAAGG ATCAGGAAGC ACAAGAACCC AAACCTAGGA AACGGGCTAA TTCTTGCTCC 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005675.3
CDS	149..1234
Translation	MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI

Target ORF information:

RefSeq Version	NM_005684.5
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005684.5

ORF Insert Sequence:

ATGAATGAAT CCAGGTGGAC TGAATGGAGG ATCCTGAACA TGAGCAGTGG CATTGTGAAT 
GTGTCCGAGC GTCACTCCTG CCCACTTGGA TTTGGCCACT ACAGTGTGGT GGATGTCTGC 
ATCTTCGAGA CAGTGGTTAT TGTGTTGCTG ACATTTCTGA TCATTGCTGG GAATCTAACA 
GTTATCTTTG TCTTTCATTG TGCTCCACTG TTACATCATT ATACTACCAG CTATTTCATT 
CAGACGATGG CATATGCTGA TCTTTTCGTT GGAGTTAGCT GCTTGGTTCC TACTCTGTCA 
CTTCTCCACT ACTCCACAGG TGTCCACGAG TCATTGACTT GCCAGGTTTT TGGATATATC 
ATCTCAGTTC TAAAAAGTGT TTCTATGGCA TGTCTTGCTT GCATCAGTGT GGATCGTTAT 
CTTGCAATAA CCAAGCCTCT TTCCTACAAT CAACTGGTCA CCCCTTGTCG CTTGAGAATT 
TGCATTATTT TGATCTGGAT CTACTCCTGC CTAATTTTCT TGCCTTCCTT TTTTGGCTGG 
GGGAAACCTG GTTACCATGG TGACATTTTT GAATGGTGTG CCACGTCTTG GCTCACCAGT 
GCCTATTTTA CTGGCTTTAT TGTTTGTTTA CTTTATGCTC CTGCTGCCTT TGTTGTCTGC 
TTCACTTACT TCCACATTTT CAAAATTTGC CGTCAGCACA CCAAAGAGAT AAATGACCGA 
AGAGCCCGAT TCCCTAGTCA TGAGGTAGAT TCTTCCAGAG AGACTGGACA CAGCCCTGAC 
CGTCGCTACG CCATGGTTTT GTTTAGGATA ACCAGTGTAT TTTATATGCT GTGGCTCCCC 
TATATAATTT ACTTTCTTCT AGAAAGCTCC CGGGTCTTGG ACAATCCAAC TCTGTCCTTC 
TTAACAACCT GGCTTGCAAT AAGTAATAGT TTTTGTAACT GTGTAATATA CAGCCTCTCC 
AACAGCGTTT TCCGGCTAGG CCTCCGAAGA CTGTCTGAGA CAATGTGCAC ATCCTGTATG 
TGTGTGAAGG ATCAGGAAGC ACAAGAACCC AAACCTAGGA AACGGGCTAA TTCTTGCTCC 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPR52 ( NM_005684.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005675.3 Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.

Price & Availability↑

CloneID	OHu30665
Clone ID Related Accession (Same CDS sequence)	NM_005684.5 , NM_005684.4
Accession Version	NM_005684.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	G-protein coupled receptor 52
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC095532.1, AL022171.1, BC069460.1, DA174341.1 and DB168074.1. On May 13, 2008 this sequence version replaced NM_005684.3. ##Evidence-Data-START## Transcript is intronless :: BC095532.1 [ECO:0000345] ##Evidence-Data-END##

ATGAATGAAT CCAGGTGGAC TGAATGGAGG ATCCTGAACA TGAGCAGTGG CATTGTGAAT 
GTGTCCGAGC GTCACTCCTG CCCACTTGGA TTTGGCCACT ACAGTGTGGT GGATGTCTGC 
ATCTTCGAGA CAGTGGTTAT TGTGTTGCTG ACATTTCTGA TCATTGCTGG GAATCTAACA 
GTTATCTTTG TCTTTCATTG TGCTCCACTG TTACATCATT ATACTACCAG CTATTTCATT 
CAGACGATGG CATATGCTGA TCTTTTCGTT GGAGTTAGCT GCTTGGTTCC TACTCTGTCA 
CTTCTCCACT ACTCCACAGG TGTCCACGAG TCATTGACTT GCCAGGTTTT TGGATATATC 
ATCTCAGTTC TAAAAAGTGT TTCTATGGCA TGTCTTGCTT GCATCAGTGT GGATCGTTAT 
CTTGCAATAA CCAAGCCTCT TTCCTACAAT CAACTGGTCA CCCCTTGTCG CTTGAGAATT 
TGCATTATTT TGATCTGGAT CTACTCCTGC CTAATTTTCT TGCCTTCCTT TTTTGGCTGG 
GGGAAACCTG GTTACCATGG TGACATTTTT GAATGGTGTG CCACGTCTTG GCTCACCAGT 
GCCTATTTTA CTGGCTTTAT TGTTTGTTTA CTTTATGCTC CTGCTGCCTT TGTTGTCTGC 
TTCACTTACT TCCACATTTT CAAAATTTGC CGTCAGCACA CCAAAGAGAT AAATGACCGA 
AGAGCCCGAT TCCCTAGTCA TGAGGTAGAT TCTTCCAGAG AGACTGGACA CAGCCCTGAC 
CGTCGCTACG CCATGGTTTT GTTTAGGATA ACCAGTGTAT TTTATATGCT GTGGCTCCCC 
TATATAATTT ACTTTCTTCT AGAAAGCTCC CGGGTCTTGG ACAATCCAAC TCTGTCCTTC 
TTAACAACCT GGCTTGCAAT AAGTAATAGT TTTTGTAACT GTGTAATATA CAGCCTCTCC 
AACAGCGTTT TCCGGCTAGG CCTCCGAAGA CTGTCTGAGA CAATGTGCAC ATCCTGTATG 
TGTGTGAAGG ATCAGGAAGC ACAAGAACCC AAACCTAGGA AACGGGCTAA TTCTTGCTCC 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005675.3
CDS	39..1124
Translation	MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI

Target ORF information:

RefSeq Version	NM_005684.4
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein-coupled receptor 52 (GPR52), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005684.4

ORF Insert Sequence:

ATGAATGAAT CCAGGTGGAC TGAATGGAGG ATCCTGAACA TGAGCAGTGG CATTGTGAAT 
GTGTCCGAGC GTCACTCCTG CCCACTTGGA TTTGGCCACT ACAGTGTGGT GGATGTCTGC 
ATCTTCGAGA CAGTGGTTAT TGTGTTGCTG ACATTTCTGA TCATTGCTGG GAATCTAACA 
GTTATCTTTG TCTTTCATTG TGCTCCACTG TTACATCATT ATACTACCAG CTATTTCATT 
CAGACGATGG CATATGCTGA TCTTTTCGTT GGAGTTAGCT GCTTGGTTCC TACTCTGTCA 
CTTCTCCACT ACTCCACAGG TGTCCACGAG TCATTGACTT GCCAGGTTTT TGGATATATC 
ATCTCAGTTC TAAAAAGTGT TTCTATGGCA TGTCTTGCTT GCATCAGTGT GGATCGTTAT 
CTTGCAATAA CCAAGCCTCT TTCCTACAAT CAACTGGTCA CCCCTTGTCG CTTGAGAATT 
TGCATTATTT TGATCTGGAT CTACTCCTGC CTAATTTTCT TGCCTTCCTT TTTTGGCTGG 
GGGAAACCTG GTTACCATGG TGACATTTTT GAATGGTGTG CCACGTCTTG GCTCACCAGT 
GCCTATTTTA CTGGCTTTAT TGTTTGTTTA CTTTATGCTC CTGCTGCCTT TGTTGTCTGC 
TTCACTTACT TCCACATTTT CAAAATTTGC CGTCAGCACA CCAAAGAGAT AAATGACCGA 
AGAGCCCGAT TCCCTAGTCA TGAGGTAGAT TCTTCCAGAG AGACTGGACA CAGCCCTGAC 
CGTCGCTACG CCATGGTTTT GTTTAGGATA ACCAGTGTAT TTTATATGCT GTGGCTCCCC 
TATATAATTT ACTTTCTTCT AGAAAGCTCC CGGGTCTTGG ACAATCCAAC TCTGTCCTTC 
TTAACAACCT GGCTTGCAAT AAGTAATAGT TTTTGTAACT GTGTAATATA CAGCCTCTCC 
AACAGCGTTT TCCGGCTAGG CCTCCGAAGA CTGTCTGAGA CAATGTGCAC ATCCTGTATG 
TGTGTGAAGG ATCAGGAAGC ACAAGAACCC AAACCTAGGA AACGGGCTAA TTCTTGCTCC 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.
eLife4(2015 Mar)
Yao Y,Cui X,Al-Ramahi I,Sun X,Li B,Hou J,Difiglia M,Palacino J,Wu ZY,Ma L,Botas J,Lu B

Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.
PloS one9(2)e90134(2014)
Komatsu H,Maruyama M,Yao S,Shinohara T,Sakuma K,Imaichi S,Chikatsu T,Kuniyeda K,Siu FK,Peng LS,Zhuo K,Mun LS,Han TM,Matsumoto Y,Hashimoto T,Miyajima N,Itoh Y,Ogi K,Habata Y,Mori M

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.
Brain research. Molecular brain research64(2)193-8(1999 Feb)
Sawzdargo M,Nguyen T,Lee DK,Lynch KR,Cheng R,Heng HH,George SR,O'Dowd BF

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GPR52 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム