BOD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BOD1
Entrez Gene ID	91272
Full Name	biorientation of chromosomes in cell division 1
Synonyms	FAM44B
General protein information	Preferred Names biorientation of chromosomes in cell division 1 Names biorientation of chromosomes in cell division protein 1 biorientation defective 1 family with sequence similarity 44, member B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q35.2
Disorder MIM:	616745

mRNA and Protein(s)

mRNA	Protein	Name
NM_138369.3	NP_612378.1	biorientation of chromosomes in cell division protein 1 isoform a
NM_138369.2	NP_612378.1	biorientation of chromosomes in cell division protein 1 isoform a
NM_001159651.3	NP_001153123.1	biorientation of chromosomes in cell division protein 1 isoform b
XM_017010017.2	XP_016865506.1	biorientation of chromosomes in cell division protein 1 isoform X1
NM_001159651.1	NP_001153123.1	biorientation of chromosomes in cell division protein 1 isoform b
XM_017010017.1	XP_016865506.1	biorientation of chromosomes in cell division protein 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BOD1	NP_612378.1
Gallus gallus (chicken)	BOD1	XP_414535.2
Canis lupus familiaris (dog)	BOD1	XP_854296.1
Bos taurus (cattle)	BOD1	NP_001069668.1
Mus musculus (house mouse)	Bod1	NP_001020090.1
Rattus norvegicus (Norway rat)	Bod1	NP_001013876.2
Danio rerio (zebrafish)	bod1	NP_001070180.1
Pan troglodytes (chimpanzee)	BOD1	XP_527124.3
Xenopus tropicalis (tropical clawed frog)	bod1	NP_001007495.1
	BOD1	XP_001101185.1

Gene Ontology
Bibliography

Related articles in PubMed

The Ndc80 complex targets Bod1 to human mitotic kinetochores.
Schleicher K, Porter M, Ten Have S, Sundaramoorthy R, Porter IM, Swedlow JR
Open biology7(11)(2017 Nov)

Radiation induces premature chromatid separation via the miR-142-3p/Bod1 pathway in carcinoma cells.
Pan D, Du Y, Ren Z, Chen Y, Li X, Wang J, Hu B
Oncotarget7(37)60432-60445(2016 Sep)

BOD1 Is Required for Cognitive Function in Humans and Drosophila.
Esmaeeli-Nieh S, Fenckova M, Porter IM, Motazacker MM, Nijhof B, Castells-Nobau A, Asztalos Z, Wei?mann R, Behjati F, Tzschach A, Felbor U, Scherthan H, Sayfati SM, Ropers HH, Kahrizi K, Najmabadi H, Swedlow JR, Schenck A, Kuss AW
PLoS genetics12(5)e1006022(2016 May)

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L
Human molecular genetics24(6)1791-800(2015 Mar)

Bod1 regulates protein phosphatase 2A at mitotic kinetochores.
Porter IM, Schleicher K, Porter M, Swedlow JR
Nature communications42677(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we established two Drosophila models, where neuron-specific knockdown of BOD1 caused pronounced learning deficits and significant abnormalities in synapse morphology. Together our results reveal novel postmitotic functions of BOD1 as well as pathogenic mechanisms that strongly support a causative role of BOD1 deficiency in the aetiology of intellectual disability.
Title: BOD1 Is Required for Cognitive Function in Humans and Drosophila.

Bod1 regulates protein phosphatase 2A at mitotic kinetochores.
Title: Bod1 regulates protein phosphatase 2A at mitotic kinetochores.

Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles.
Title: Bod1, a novel kinetochore protein required for chromosome biorientation.

The following BOD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BOD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03051	NM_001159651.3 Latest version!	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu06082	NM_138369.3 Latest version!	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu96184	XM_017010017.2 Latest version!	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu06082	NM_138369.2	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu03051	NM_001159651.1	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu96184	XM_017010017.1	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BOD1 ( NM_001159651.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153123.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03051
Clone ID Related Accession (Same CDS sequence)	NM_001159651.3 , NM_001159651.1
Accession Version	NM_001159651.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-30
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC010339.8. On Oct 31, 2019 this sequence version replaced NM_001159651.2. ##Evidence-Data-START## Transcript exon combination :: BC003114.1, CD106034.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAAATACGCC AGACACCTTT TGAAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153123.1
CDS	215..604
Translation	MADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQIRQTPFES

Target ORF information:

RefSeq Version	NM_001159651.3
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159651.3

ORF Insert Sequence:

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAAATACGCC AGACACCTTT TGAAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOD1 ( NM_001159651.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153123.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03051
Clone ID Related Accession (Same CDS sequence)	NM_001159651.3 , NM_001159651.1
Accession Version	NM_001159651.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-10
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA953541.1, BC003114.1, DA506589.1 and BQ881883.1. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform b) has a distinct and shorter C-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: BC003114.1, SRR1163655.681018.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAAATACGCC AGACACCTTT TGAAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153123.1
CDS	228..617
Translation	MADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQIRQTPFES

Target ORF information:

RefSeq Version	NM_001159651.1
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159651.1

ORF Insert Sequence:

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAAATACGCC AGACACCTTT TGAAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOD1 ( NM_138369.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612378.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06082
Clone ID Related Accession (Same CDS sequence)	NM_138369.3 , NM_138369.2
Accession Version	NM_138369.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC007436.2, DA506589.1 and BQ881883.1. On May 17, 2019 this sequence version replaced NM_138369.2. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.644427.1, SRR7346977.572259.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311086.9/ ENSP00000309644.4 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAGTCAGGGA TGTTGGAAGC TGGAGTAGAC AGGATTATTT CTCAGGTGGT GGATCCAAAA 
CTTAACCACA TCTTCAGGCC ACAAATAGAA CGAGCAATTC ATGAGTTCCT GGCGGCCCAG 
AAAAAAGCAG CTGTGCCAGC ACCCCCTCCA GAGCCCGAAG GCCAGGACCC TCCAGCTCCA 
TCTCAGGACA CTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612378.1
CDS	215..772
Translation	MADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQSGMLEAGVDRIISQVVDPKLNHIFRPQIERAIHEFLAAQKKAAVPAPPPEPEGQDPPAPSQDTS

Target ORF information:

RefSeq Version	NM_138369.3
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138369.3

ORF Insert Sequence:

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAGTCAGGGA TGTTGGAAGC TGGAGTAGAC AGGATTATTT CTCAGGTGGT GGATCCAAAA 
CTTAACCACA TCTTCAGGCC ACAAATAGAA CGAGCAATTC ATGAGTTCCT GGCGGCCCAG 
AAAAAAGCAG CTGTGCCAGC ACCCCCTCCA GAGCCCGAAG GCCAGGACCC TCCAGCTCCA 
TCTCAGGACA CTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOD1 ( NM_138369.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612378.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06082
Clone ID Related Accession (Same CDS sequence)	NM_138369.3 , NM_138369.2
Accession Version	NM_138369.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-11
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA953541.1, BC007436.2, DA506589.1 and BQ881883.1. On May 1, 2009 this sequence version replaced NM_138369.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1163655.126516.1, BC007436.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAGTCAGGGA TGTTGGAAGC TGGAGTAGAC AGGATTATTT CTCAGGTGGT GGATCCAAAA 
CTTAACCACA TCTTCAGGCC ACAAATAGAA CGAGCAATTC ATGAGTTCCT GGCGGCCCAG 
AAAAAAGCAG CTGTGCCAGC ACCCCCTCCA GAGCCCGAAG GCCAGGACCC TCCAGCTCCA 
TCTCAGGACA CTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612378.1
CDS	228..785
Translation	MADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQSGMLEAGVDRIISQVVDPKLNHIFRPQIERAIHEFLAAQKKAAVPAPPPEPEGQDPPAPSQDTS

Target ORF information:

RefSeq Version	NM_138369.2
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138369.2

ORF Insert Sequence:

ATGGCGGACG GCGGCGGCGG CGGGGGAACT GGCGCGGTGG GCGGCGGCGG AACTAGCCAG 
GCCTCTGCCG GGGCAGCGAC TGGCGCTACT GGGGCCAGCG GGGGCGGTGG CCCCATCAAC 
CCGGCCTCGC TGCCTCCCGG CGACCCGCAG CTCATCGCTC TCATCGTGGA GCAGCTCAAG 
AGCCGGGGCC TTTTTGACAG CTTCCGCCGG GACTGCCTGG CCGACGTGGA CACCAAGCCA 
GCTTACCAAA ACCTGAGGCA GAAAGTGGAT AATTTTGTGT CAACACATCT GGACAAGCAG 
GAATGGAATC CTACGATGAA CAAAAACCAG TTGCGAAATG GTCTGAGGCA GAGTGTGGTT 
CAGTCAGGGA TGTTGGAAGC TGGAGTAGAC AGGATTATTT CTCAGGTGGT GGATCCAAAA 
CTTAACCACA TCTTCAGGCC ACAAATAGAA CGAGCAATTC ATGAGTTCCT GGCGGCCCAG 
AAAAAAGCAG CTGTGCCAGC ACCCCCTCCA GAGCCCGAAG GCCAGGACCC TCCAGCTCCA 
TCTCAGGACA CTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOD1 ( XM_017010017.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865506.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu96184
Clone ID Related Accession (Same CDS sequence)	XM_017010017.2 , XM_017010017.1
Accession Version	XM_017010017.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017010017.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAAGGT CAACGTTGAC GCCATCTGGG GTGCGCCTGG AATCGAGCAG GCCGTTTCTG 
CCGCGTCCAC CACAACCTCT GCTGTATCAG AGGGGGCCTT CGCCGCCGCC GCCCCCACCA 
CCGCCCCTGC CGCCATCGCC ACCTCCGCCG CTGCCGCCTT GGGGCCCTCC TCCTTCACCG 
CCCCCTTCAC CACCTCTACA CGTTCTAGGC CTTCTGTCCT GGAGAAGAAG CTATAGTCGT 
TCTCCCTTGT GGGCCCGGGG CGCAGCCATG GCGGACGGCG GCGGCGGCGG GGGAACTGGC 
GCGGTGGGCG GCGGCGGAAC TAGCCAGGCC TCTGCCGGGG CAGCGACTGG CGCTACTGGG 
GCCAGCGGGG GCGGTGGCCC CATCAACCCG GCCTCGCTGC CTCCCGGCGA CCCGCAGCTC 
ATCGCTCTCA TCGTGGAGCA GCTCAAGAGC CGGGGCCTTT TTGACAGCTT CCGCCGGGAC 
TGCCTGGCCG ACGTGGACAC CAAGAATACG CCAGACACCT TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865506.1
CDS	370..894
Translation	MQRSTLTPSGVRLESSRPFLPRPPQPLLYQRGPSPPPPPPPPLPPSPPPPLPPWGPPPSPPPSPPLHVLGLLSWRRSYSRSPLWARGAAMADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKNTPDTF

Target ORF information:

RefSeq Version	XM_017010017.2
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010017.2

ORF Insert Sequence:

ATGCAAAGGT CAACGTTGAC GCCATCTGGG GTGCGCCTGG AATCGAGCAG GCCGTTTCTG 
CCGCGTCCAC CACAACCTCT GCTGTATCAG AGGGGGCCTT CGCCGCCGCC GCCCCCACCA 
CCGCCCCTGC CGCCATCGCC ACCTCCGCCG CTGCCGCCTT GGGGCCCTCC TCCTTCACCG 
CCCCCTTCAC CACCTCTACA CGTTCTAGGC CTTCTGTCCT GGAGAAGAAG CTATAGTCGT 
TCTCCCTTGT GGGCCCGGGG CGCAGCCATG GCGGACGGCG GCGGCGGCGG GGGAACTGGC 
GCGGTGGGCG GCGGCGGAAC TAGCCAGGCC TCTGCCGGGG CAGCGACTGG CGCTACTGGG 
GCCAGCGGGG GCGGTGGCCC CATCAACCCG GCCTCGCTGC CTCCCGGCGA CCCGCAGCTC 
ATCGCTCTCA TCGTGGAGCA GCTCAAGAGC CGGGGCCTTT TTGACAGCTT CCGCCGGGAC 
TGCCTGGCCG ACGTGGACAC CAAGAATACG CCAGACACCT TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOD1 ( XM_017010017.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865506.1 Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X4, mRNA.

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CloneID	OHu96184
Clone ID Related Accession (Same CDS sequence)	XM_017010017.2 , XM_017010017.1
Accession Version	XM_017010017.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	biorientation of chromosomes in cell division protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAAGGT CAACGTTGAC GCCATCTGGG GTGCGCCTGG AATCGAGCAG GCCGTTTCTG 
CCGCGTCCAC CACAACCTCT GCTGTATCAG AGGGGGCCTT CGCCGCCGCC GCCCCCACCA 
CCGCCCCTGC CGCCATCGCC ACCTCCGCCG CTGCCGCCTT GGGGCCCTCC TCCTTCACCG 
CCCCCTTCAC CACCTCTACA CGTTCTAGGC CTTCTGTCCT GGAGAAGAAG CTATAGTCGT 
TCTCCCTTGT GGGCCCGGGG CGCAGCCATG GCGGACGGCG GCGGCGGCGG GGGAACTGGC 
GCGGTGGGCG GCGGCGGAAC TAGCCAGGCC TCTGCCGGGG CAGCGACTGG CGCTACTGGG 
GCCAGCGGGG GCGGTGGCCC CATCAACCCG GCCTCGCTGC CTCCCGGCGA CCCGCAGCTC 
ATCGCTCTCA TCGTGGAGCA GCTCAAGAGC CGGGGCCTTT TTGACAGCTT CCGCCGGGAC 
TGCCTGGCCG ACGTGGACAC CAAGAATACG CCAGACACCT TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865506.1
CDS	375..899
Translation	MQRSTLTPSGVRLESSRPFLPRPPQPLLYQRGPSPPPPPPPPLPPSPPPPLPPWGPPPSPPPSPPLHVLGLLSWRRSYSRSPLWARGAAMADGGGGGGTGAVGGGGTSQASAGAATGATGASGGGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKNTPDTF

Target ORF information:

RefSeq Version	XM_017010017.1
Organism	Homo sapiens(human)
Definition	Homo sapiens biorientation of chromosomes in cell division 1 (BOD1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010017.1

ORF Insert Sequence:

ATGCAAAGGT CAACGTTGAC GCCATCTGGG GTGCGCCTGG AATCGAGCAG GCCGTTTCTG 
CCGCGTCCAC CACAACCTCT GCTGTATCAG AGGGGGCCTT CGCCGCCGCC GCCCCCACCA 
CCGCCCCTGC CGCCATCGCC ACCTCCGCCG CTGCCGCCTT GGGGCCCTCC TCCTTCACCG 
CCCCCTTCAC CACCTCTACA CGTTCTAGGC CTTCTGTCCT GGAGAAGAAG CTATAGTCGT 
TCTCCCTTGT GGGCCCGGGG CGCAGCCATG GCGGACGGCG GCGGCGGCGG GGGAACTGGC 
GCGGTGGGCG GCGGCGGAAC TAGCCAGGCC TCTGCCGGGG CAGCGACTGG CGCTACTGGG 
GCCAGCGGGG GCGGTGGCCC CATCAACCCG GCCTCGCTGC CTCCCGGCGA CCCGCAGCTC 
ATCGCTCTCA TCGTGGAGCA GCTCAAGAGC CGGGGCCTTT TTGACAGCTT CCGCCGGGAC 
TGCCTGGCCG ACGTGGACAC CAAGAATACG CCAGACACCT TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Ndc80 complex targets Bod1 to human mitotic kinetochores.
Open biology7(11)(2017 Nov)
Schleicher K,Porter M,Ten Have S,Sundaramoorthy R,Porter IM,Swedlow JR

Radiation induces premature chromatid separation via the miR-142-3p/Bod1 pathway in carcinoma cells.
Oncotarget7(37)60432-60445(2016 Sep)
Pan D,Du Y,Ren Z,Chen Y,Li X,Wang J,Hu B

BOD1 Is Required for Cognitive Function in Humans and Drosophila.
PLoS genetics12(5)e1006022(2016 May)
Esmaeeli-Nieh S,Fenckova M,Porter IM,Motazacker MM,Nijhof B,Castells-Nobau A,Asztalos Z,Wei?mann R,Behjati F,Tzschach A,Felbor U,Scherthan H,Sayfati SM,Ropers HH,Kahrizi K,Najmabadi H,Swedlow JR,Schenck A,Kuss AW

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
Human molecular genetics24(6)1791-800(2015 Mar)
He M,Xu M,Zhang B,Liang J,Chen P,Lee JY,Johnson TA,Li H,Yang X,Dai J,Liang L,Gui L,Qi Q,Huang J,Li Y,Adair LS,Aung T,Cai Q,Cheng CY,Cho MC,Cho YS,Chu M,Cui B,Gao YT,Go MJ,Gu D,Gu W,Guo H,Hao Y,Hong J,Hu Z,Hu Y,Huang J,Hwang JY,Ikram MK,Jin G,Kang DH,Khor CC,Kim BJ,Kim HT,Kubo M,Lee J,Lee J,Lee NR,Li R,Li J,Liu J,Longe J,Lu W,Lu X,Miao X,Okada Y,Ong RT,Qiu G,Seielstad M,Sim X,Song H,Takeuchi F,Tanaka T,Taylor PR,Wang L,Wang W,Wang Y,Wu C,Wu Y,Xiang YB,Yamamoto K,Yang H,Liao M,Yokota M,Young T,Zhang X,Kato N,Wang QK,Zheng W,Hu FB,Lin D,Shen H,Teo YY,Mo Z,Wong TY,Lin X,Mohlke KL,Ning G,Tsunoda T,Han BG,Shu XO,Tai ES,Wu T,Qi L

Bod1 regulates protein phosphatase 2A at mitotic kinetochores.
Nature communications42677(2013)
Porter IM,Schleicher K,Porter M,Swedlow JR

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BOD1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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