ENDOU cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ENDOU
Entrez Gene ID	8909
Full Name	endonuclease, poly(U) specific
Synonyms	P11,PP11,PRSS26
General protein information	Preferred Names endonuclease, poly(U) specific Names poly(U)-specific endoribonuclease 22 serine protease 26 serine protease endonuclease, polyU-specific placental protein 11 protein endoU uridylate-specific endoribonuclease
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.11
Summary	This gene encodes a protein with protease activity and is expressed in the placenta. The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants have been found for this protein. [provided by RefSeq, Feb 2010].
Disorder MIM:	606720

mRNA and Protein(s)

mRNA	Protein	Name
NM_001172440.1	NP_001165911.1	poly(U)-specific endoribonuclease isoform 3 precursor
NM_001172439.2	NP_001165910.1	poly(U)-specific endoribonuclease isoform 1 precursor
NM_001172439.1	NP_001165910.1	poly(U)-specific endoribonuclease isoform 1 precursor
NM_001172440.2	NP_001165911.1	poly(U)-specific endoribonuclease isoform 3 precursor
NM_006025.4	NP_006016.1	poly(U)-specific endoribonuclease isoform 2 precursor
NM_006025.3	NP_006016.1	poly(U)-specific endoribonuclease isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENDOU	NP_001165910.1
Pan troglodytes (chimpanzee)	ENDOU	XP_522366.2
Mus musculus (house mouse)	Endou	NP_001162164.1
Drosophila melanogaster (fruit fly)	CG2145	NP_572668.1
	ENDOU	XP_001097705.1
Gallus gallus (chicken)	ENDOU	XP_003643169.1
Danio rerio (zebrafish)	endou	NP_001074167.1
Rattus norvegicus (Norway rat)	Endou	NP_001177998.1
Caenorhabditis elegans (roundworm)	K02A11.3	NP_492590.1
Canis lupus familiaris (dog)	ENDOU	XP_005636984.1
Bos taurus (cattle)	ENDOU	NP_001095560.1
Xenopus tropicalis (tropical clawed frog)	LOC100490819	XP_002935698.2

Gene Ontology
Bibliography

Related articles in PubMed

The tumor marker human placental protein 11 is an endoribonuclease.
Laneve P, Gioia U, Ragno R, Altieri F, Di Franco C, Santini T, Arceci M, Bozzoni I, Caffarelli E
The Journal of biological chemistry283(50)34712-9(2008 Dec)

Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
Gioia U, Laneve P, Dlakic M, Arceci M, Bozzoni I, Caffarelli E
The Journal of biological chemistry280(19)18996-9002(2005 May)

Homology of placental protein 11 and pea seed albumin 2 with vitronectin.
Jenne D
Biochemical and biophysical research communications176(3)1000-6(1991 May)

Cloning and expression of a cDNA encoding human placental protein 11, a putative serine protease with diagnostic significance as a tumor marker.
Grundmann U, R?misch J, Siebold B, Bohn H, Amann E
DNA and cell biology9(4)243-50(1990 May)

Immunohistochemical detection of pregnancy-specific protein (SP1) and placenta-specific tissue proteins (PP5, PP10, PP11 and PP12) in ovarian adenocarcinomas.
Inaba N, Ishige H, Ijichi M, Satoh N, Ohkawa R, Sekiya S, Shirotake S, Takamizawa H, Renk T, Bohn H
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine3(5-6)379-89(1982)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

human placental protein 11 is an endoribonuclease
Title: The tumor marker human placental protein 11 is an endoribonuclease.

The following ENDOU gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENDOU cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04485	NM_001172439.2 Latest version!	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$174.50-$244.30 $349.00
OHu11434	NM_006025.4 Latest version!	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu11593	NM_001172440.2 Latest version!	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$202.30 $289.00
View Old Accession Versions >>
OHu04485	NM_001172439.1	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$174.50-$244.30 $349.00
OHu11593	NM_001172440.1	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$202.30 $289.00
OHu11434	NM_006025.3	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ENDOU ( NM_001172439.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165910.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04485
Clone ID Related Accession (Same CDS sequence)	NM_001172439.2 , NM_001172439.1
Accession Version	NM_001172439.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK075446.1, BC069698.1 and AI039727.1. On Nov 22, 2018 this sequence version replaced NM_001172439.1. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AK075446.1, BC069698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000422538.8/ ENSP00000397679.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGGAAAA 
ATAGAATCCT GTGCATCTCG ATGTAATGAG AAATTTAACC GGGACGCTGC CTGCCAGTGT 
GACCGCCGGT GTCTCTGGCA TGGGAACTGC TGTGAAGACT ATGAACATCT GTGTACTGAG 
GACCACAAAG AGTCAGAGCC ATTGCCACAG CTGGAGGAAG AGACAGAAGA GGCCCTCGCC 
AGCAACTTGT ACTCGGCACC CACCTCCTGC CAGGGCCGCT GCTACGAAGC CTTTGACAAG 
CACCACCAAT GTCACTGCAA TGCCCGCTGC CAAGAGTTTG GGAACTGCTG CAAGGATTTT 
GAGAGCCTGT GTAGTGACCA CGAGGTCTCC CACAGCAGTG ATGCCATAAC AAAAGAGGAG 
ATTCAGAGCA TCTCTGAGAA GATCTACAGG GCAGACACCA ACAAAGCCCA GAAGGAAGAC 
ATCGTTCTCA ATAGCCAAAA CTGCATCTCC CCGTCAGAGA CCAGAAACCA AGTGGATCGC 
TGCCCAAAGC CACTCTTCAC TTATGTCAAT GAGAAGCTGT TCTCCAAGCC CACCTATGCA 
GCCTTCATCA ACCTCCTCAA CAACTACCAG CGGGCAACAG GCCATGGGGA GCACTTCAGT 
GCCCAGGAGC TGGCCGAGCA GGACGCCTTC CTCAGAGAGA TCATGAAGAC AGCAGTCATG 
AAGGAGCTCT ACAGCTTCCT CCATCACCAG AATCGCTATG GCTCAGAGCA AGAGTTTGTC 
GATGACTTGA AGAACATGTG GTTTGGGCTC TATTCAAGAG GCAATGAAGA GGGGGACTCG 
AGTGGCTTTG AACATGTCTT CTCAGGTGAG GTAAAAAAAG GCAAGGTTAC TGGCTTCCAT 
AACTGGATCC GCTTCTACCT GGAGGAGAAG GAGGGTCTGG TTGACTATTA CAGTCACATC 
TACGATGGGC CTTGGGATTC TTACCCCGAT GTGCTGGCAA TGCAGTTCAA CTGGGACGGC 
TACTATAAGG AAGTGGGCTC TGCTTTCATC GGCAGCAGCC CTGAGTTTGA GTTTGCACTC 
TACTCCCTGT GCTTCATCGC CAGGCCAGGC AAAGTGTGCC AGTTAAGCCT GGGAGGATAT 
CCCTTAGCTG TCCGGACATA TACCTGGGAC AAGTCCACCT ATGGGAATGG CAAGAAGTAC 
ATCGCCACAG CCTACATAGT GTCTTCCACC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165910.1
CDS	78..1310
Translation	MRACISLVLAVLCGLAWAGKIESCASRCNEKFNRDAACQCDRRCLWHGNCCEDYEHLCTEDHKESEPLPQLEEETEEALASNLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_001172439.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172439.2

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGGAAAA 
ATAGAATCCT GTGCATCTCG ATGTAATGAG AAATTTAACC GGGACGCTGC CTGCCAGTGT 
GACCGCCGGT GTCTCTGGCA TGGGAACTGC TGTGAAGACT ATGAACATCT GTGTACTGAG 
GACCACAAAG AGTCAGAGCC ATTGCCACAG CTGGAGGAAG AGACAGAAGA GGCCCTCGCC 
AGCAACTTGT ACTCGGCACC CACCTCCTGC CAGGGCCGCT GCTACGAAGC CTTTGACAAG 
CACCACCAAT GTCACTGCAA TGCCCGCTGC CAAGAGTTTG GGAACTGCTG CAAGGATTTT 
GAGAGCCTGT GTAGTGACCA CGAGGTCTCC CACAGCAGTG ATGCCATAAC AAAAGAGGAG 
ATTCAGAGCA TCTCTGAGAA GATCTACAGG GCAGACACCA ACAAAGCCCA GAAGGAAGAC 
ATCGTTCTCA ATAGCCAAAA CTGCATCTCC CCGTCAGAGA CCAGAAACCA AGTGGATCGC 
TGCCCAAAGC CACTCTTCAC TTATGTCAAT GAGAAGCTGT TCTCCAAGCC CACCTATGCA 
GCCTTCATCA ACCTCCTCAA CAACTACCAG CGGGCAACAG GCCATGGGGA GCACTTCAGT 
GCCCAGGAGC TGGCCGAGCA GGACGCCTTC CTCAGAGAGA TCATGAAGAC AGCAGTCATG 
AAGGAGCTCT ACAGCTTCCT CCATCACCAG AATCGCTATG GCTCAGAGCA AGAGTTTGTC 
GATGACTTGA AGAACATGTG GTTTGGGCTC TATTCAAGAG GCAATGAAGA GGGGGACTCG 
AGTGGCTTTG AACATGTCTT CTCAGGTGAG GTAAAAAAAG GCAAGGTTAC TGGCTTCCAT 
AACTGGATCC GCTTCTACCT GGAGGAGAAG GAGGGTCTGG TTGACTATTA CAGTCACATC 
TACGATGGGC CTTGGGATTC TTACCCCGAT GTGCTGGCAA TGCAGTTCAA CTGGGACGGC 
TACTATAAGG AAGTGGGCTC TGCTTTCATC GGCAGCAGCC CTGAGTTTGA GTTTGCACTC 
TACTCCCTGT GCTTCATCGC CAGGCCAGGC AAAGTGTGCC AGTTAAGCCT GGGAGGATAT 
CCCTTAGCTG TCCGGACATA TACCTGGGAC AAGTCCACCT ATGGGAATGG CAAGAAGTAC 
ATCGCCACAG CCTACATAGT GTCTTCCACC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENDOU ( NM_001172439.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165910.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04485
Clone ID Related Accession (Same CDS sequence)	NM_001172439.2 , NM_001172439.1
Accession Version	NM_001172439.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA841959.1, AK075446.1, BC069698.1 and AI039727.1. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AK075446.1, BC069698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGGAAAA 
ATAGAATCCT GTGCATCTCG ATGTAATGAG AAATTTAACC GGGACGCTGC CTGCCAGTGT 
GACCGCCGGT GTCTCTGGCA TGGGAACTGC TGTGAAGACT ATGAACATCT GTGTACTGAG 
GACCACAAAG AGTCAGAGCC ATTGCCACAG CTGGAGGAAG AGACAGAAGA GGCCCTCGCC 
AGCAACTTGT ACTCGGCACC CACCTCCTGC CAGGGCCGCT GCTACGAAGC CTTTGACAAG 
CACCACCAAT GTCACTGCAA TGCCCGCTGC CAAGAGTTTG GGAACTGCTG CAAGGATTTT 
GAGAGCCTGT GTAGTGACCA CGAGGTCTCC CACAGCAGTG ATGCCATAAC AAAAGAGGAG 
ATTCAGAGCA TCTCTGAGAA GATCTACAGG GCAGACACCA ACAAAGCCCA GAAGGAAGAC 
ATCGTTCTCA ATAGCCAAAA CTGCATCTCC CCGTCAGAGA CCAGAAACCA AGTGGATCGC 
TGCCCAAAGC CACTCTTCAC TTATGTCAAT GAGAAGCTGT TCTCCAAGCC CACCTATGCA 
GCCTTCATCA ACCTCCTCAA CAACTACCAG CGGGCAACAG GCCATGGGGA GCACTTCAGT 
GCCCAGGAGC TGGCCGAGCA GGACGCCTTC CTCAGAGAGA TCATGAAGAC AGCAGTCATG 
AAGGAGCTCT ACAGCTTCCT CCATCACCAG AATCGCTATG GCTCAGAGCA AGAGTTTGTC 
GATGACTTGA AGAACATGTG GTTTGGGCTC TATTCAAGAG GCAATGAAGA GGGGGACTCG 
AGTGGCTTTG AACATGTCTT CTCAGGTGAG GTAAAAAAAG GCAAGGTTAC TGGCTTCCAT 
AACTGGATCC GCTTCTACCT GGAGGAGAAG GAGGGTCTGG TTGACTATTA CAGTCACATC 
TACGATGGGC CTTGGGATTC TTACCCCGAT GTGCTGGCAA TGCAGTTCAA CTGGGACGGC 
TACTATAAGG AAGTGGGCTC TGCTTTCATC GGCAGCAGCC CTGAGTTTGA GTTTGCACTC 
TACTCCCTGT GCTTCATCGC CAGGCCAGGC AAAGTGTGCC AGTTAAGCCT GGGAGGATAT 
CCCTTAGCTG TCCGGACATA TACCTGGGAC AAGTCCACCT ATGGGAATGG CAAGAAGTAC 
ATCGCCACAG CCTACATAGT GTCTTCCACC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165910.1
CDS	160..1392
Translation	MRACISLVLAVLCGLAWAGKIESCASRCNEKFNRDAACQCDRRCLWHGNCCEDYEHLCTEDHKESEPLPQLEEETEEALASNLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_001172439.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172439.1

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGGAAAA 
ATAGAATCCT GTGCATCTCG ATGTAATGAG AAATTTAACC GGGACGCTGC CTGCCAGTGT 
GACCGCCGGT GTCTCTGGCA TGGGAACTGC TGTGAAGACT ATGAACATCT GTGTACTGAG 
GACCACAAAG AGTCAGAGCC ATTGCCACAG CTGGAGGAAG AGACAGAAGA GGCCCTCGCC 
AGCAACTTGT ACTCGGCACC CACCTCCTGC CAGGGCCGCT GCTACGAAGC CTTTGACAAG 
CACCACCAAT GTCACTGCAA TGCCCGCTGC CAAGAGTTTG GGAACTGCTG CAAGGATTTT 
GAGAGCCTGT GTAGTGACCA CGAGGTCTCC CACAGCAGTG ATGCCATAAC AAAAGAGGAG 
ATTCAGAGCA TCTCTGAGAA GATCTACAGG GCAGACACCA ACAAAGCCCA GAAGGAAGAC 
ATCGTTCTCA ATAGCCAAAA CTGCATCTCC CCGTCAGAGA CCAGAAACCA AGTGGATCGC 
TGCCCAAAGC CACTCTTCAC TTATGTCAAT GAGAAGCTGT TCTCCAAGCC CACCTATGCA 
GCCTTCATCA ACCTCCTCAA CAACTACCAG CGGGCAACAG GCCATGGGGA GCACTTCAGT 
GCCCAGGAGC TGGCCGAGCA GGACGCCTTC CTCAGAGAGA TCATGAAGAC AGCAGTCATG 
AAGGAGCTCT ACAGCTTCCT CCATCACCAG AATCGCTATG GCTCAGAGCA AGAGTTTGTC 
GATGACTTGA AGAACATGTG GTTTGGGCTC TATTCAAGAG GCAATGAAGA GGGGGACTCG 
AGTGGCTTTG AACATGTCTT CTCAGGTGAG GTAAAAAAAG GCAAGGTTAC TGGCTTCCAT 
AACTGGATCC GCTTCTACCT GGAGGAGAAG GAGGGTCTGG TTGACTATTA CAGTCACATC 
TACGATGGGC CTTGGGATTC TTACCCCGAT GTGCTGGCAA TGCAGTTCAA CTGGGACGGC 
TACTATAAGG AAGTGGGCTC TGCTTTCATC GGCAGCAGCC CTGAGTTTGA GTTTGCACTC 
TACTCCCTGT GCTTCATCGC CAGGCCAGGC AAAGTGTGCC AGTTAAGCCT GGGAGGATAT 
CCCTTAGCTG TCCGGACATA TACCTGGGAC AAGTCCACCT ATGGGAATGG CAAGAAGTAC 
ATCGCCACAG CCTACATAGT GTCTTCCACC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENDOU ( NM_006025.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006016.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11434
Clone ID Related Accession (Same CDS sequence)	NM_006025.4 , NM_006025.3
Accession Version	NM_006025.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC111782.1, AC004241.2 and AI039727.1. On Jun 1, 2019 this sequence version replaced NM_006025.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.20825.1, SRR1660809.161601.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGAGGAC 
CACAAAGAGT CAGAGCCATT GCCACAGCTG GAGGAAGAGA CAGAAGAGGC CCTCGCCAGC 
AACTTGTACT CGGCACCCAC CTCCTGCCAG GGCCGCTGCT ACGAAGCCTT TGACAAGCAC 
CACCAATGTC ACTGCAATGC CCGCTGCCAA GAGTTTGGGA ACTGCTGCAA GGATTTTGAG 
AGCCTGTGTA GTGACCACGA GGTCTCCCAC AGCAGTGATG CCATAACAAA AGAGGAGATT 
CAGAGCATCT CTGAGAAGAT CTACAGGGCA GACACCAACA AAGCCCAGAA GGAAGACATC 
GTTCTCAATA GCCAAAACTG CATCTCCCCG TCAGAGACCA GAAACCAAGT GGATCGCTGC 
CCAAAGCCAC TCTTCACTTA TGTCAATGAG AAGCTGTTCT CCAAGCCCAC CTATGCAGCC 
TTCATCAACC TCCTCAACAA CTACCAGCGG GCAACAGGCC ATGGGGAGCA CTTCAGTGCC 
CAGGAGCTGG CCGAGCAGGA CGCCTTCCTC AGAGAGATCA TGAAGACAGC AGTCATGAAG 
GAGCTCTACA GCTTCCTCCA TCACCAGAAT CGCTATGGCT CAGAGCAAGA GTTTGTCGAT 
GACTTGAAGA ACATGTGGTT TGGGCTCTAT TCAAGAGGCA ATGAAGAGGG GGACTCGAGT 
GGCTTTGAAC ATGTCTTCTC AGGTGAGGTA AAAAAAGGCA AGGTTACTGG CTTCCATAAC 
TGGATCCGCT TCTACCTGGA GGAGAAGGAG GGTCTGGTTG ACTATTACAG TCACATCTAC 
GATGGGCCTT GGGATTCTTA CCCCGATGTG CTGGCAATGC AGTTCAACTG GGACGGCTAC 
TATAAGGAAG TGGGCTCTGC TTTCATCGGC AGCAGCCCTG AGTTTGAGTT TGCACTCTAC 
TCCCTGTGCT TCATCGCCAG GCCAGGCAAA GTGTGCCAGT TAAGCCTGGG AGGATATCCC 
TTAGCTGTCC GGACATATAC CTGGGACAAG TCCACCTATG GGAATGGCAA GAAGTACATC 
GCCACAGCCT ACATAGTGTC TTCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006016.1
CDS	78..1187
Translation	MRACISLVLAVLCGLAWAEDHKESEPLPQLEEETEEALASNLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_006025.4
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006025.4

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGAGGAC 
CACAAAGAGT CAGAGCCATT GCCACAGCTG GAGGAAGAGA CAGAAGAGGC CCTCGCCAGC 
AACTTGTACT CGGCACCCAC CTCCTGCCAG GGCCGCTGCT ACGAAGCCTT TGACAAGCAC 
CACCAATGTC ACTGCAATGC CCGCTGCCAA GAGTTTGGGA ACTGCTGCAA GGATTTTGAG 
AGCCTGTGTA GTGACCACGA GGTCTCCCAC AGCAGTGATG CCATAACAAA AGAGGAGATT 
CAGAGCATCT CTGAGAAGAT CTACAGGGCA GACACCAACA AAGCCCAGAA GGAAGACATC 
GTTCTCAATA GCCAAAACTG CATCTCCCCG TCAGAGACCA GAAACCAAGT GGATCGCTGC 
CCAAAGCCAC TCTTCACTTA TGTCAATGAG AAGCTGTTCT CCAAGCCCAC CTATGCAGCC 
TTCATCAACC TCCTCAACAA CTACCAGCGG GCAACAGGCC ATGGGGAGCA CTTCAGTGCC 
CAGGAGCTGG CCGAGCAGGA CGCCTTCCTC AGAGAGATCA TGAAGACAGC AGTCATGAAG 
GAGCTCTACA GCTTCCTCCA TCACCAGAAT CGCTATGGCT CAGAGCAAGA GTTTGTCGAT 
GACTTGAAGA ACATGTGGTT TGGGCTCTAT TCAAGAGGCA ATGAAGAGGG GGACTCGAGT 
GGCTTTGAAC ATGTCTTCTC AGGTGAGGTA AAAAAAGGCA AGGTTACTGG CTTCCATAAC 
TGGATCCGCT TCTACCTGGA GGAGAAGGAG GGTCTGGTTG ACTATTACAG TCACATCTAC 
GATGGGCCTT GGGATTCTTA CCCCGATGTG CTGGCAATGC AGTTCAACTG GGACGGCTAC 
TATAAGGAAG TGGGCTCTGC TTTCATCGGC AGCAGCCCTG AGTTTGAGTT TGCACTCTAC 
TCCCTGTGCT TCATCGCCAG GCCAGGCAAA GTGTGCCAGT TAAGCCTGGG AGGATATCCC 
TTAGCTGTCC GGACATATAC CTGGGACAAG TCCACCTATG GGAATGGCAA GAAGTACATC 
GCCACAGCCT ACATAGTGTC TTCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENDOU ( NM_006025.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006016.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.

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CloneID	OHu11434
Clone ID Related Accession (Same CDS sequence)	NM_006025.4 , NM_006025.3
Accession Version	NM_006025.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA838842.1, BC111782.1, AC004241.2 and AI039727.1. On Feb 18, 2010 this sequence version replaced NM_006025.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: M32402.1, M36109.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGAGGAC 
CACAAAGAGT CAGAGCCATT GCCACAGCTG GAGGAAGAGA CAGAAGAGGC CCTCGCCAGC 
AACTTGTACT CGGCACCCAC CTCCTGCCAG GGCCGCTGCT ACGAAGCCTT TGACAAGCAC 
CACCAATGTC ACTGCAATGC CCGCTGCCAA GAGTTTGGGA ACTGCTGCAA GGATTTTGAG 
AGCCTGTGTA GTGACCACGA GGTCTCCCAC AGCAGTGATG CCATAACAAA AGAGGAGATT 
CAGAGCATCT CTGAGAAGAT CTACAGGGCA GACACCAACA AAGCCCAGAA GGAAGACATC 
GTTCTCAATA GCCAAAACTG CATCTCCCCG TCAGAGACCA GAAACCAAGT GGATCGCTGC 
CCAAAGCCAC TCTTCACTTA TGTCAATGAG AAGCTGTTCT CCAAGCCCAC CTATGCAGCC 
TTCATCAACC TCCTCAACAA CTACCAGCGG GCAACAGGCC ATGGGGAGCA CTTCAGTGCC 
CAGGAGCTGG CCGAGCAGGA CGCCTTCCTC AGAGAGATCA TGAAGACAGC AGTCATGAAG 
GAGCTCTACA GCTTCCTCCA TCACCAGAAT CGCTATGGCT CAGAGCAAGA GTTTGTCGAT 
GACTTGAAGA ACATGTGGTT TGGGCTCTAT TCAAGAGGCA ATGAAGAGGG GGACTCGAGT 
GGCTTTGAAC ATGTCTTCTC AGGTGAGGTA AAAAAAGGCA AGGTTACTGG CTTCCATAAC 
TGGATCCGCT TCTACCTGGA GGAGAAGGAG GGTCTGGTTG ACTATTACAG TCACATCTAC 
GATGGGCCTT GGGATTCTTA CCCCGATGTG CTGGCAATGC AGTTCAACTG GGACGGCTAC 
TATAAGGAAG TGGGCTCTGC TTTCATCGGC AGCAGCCCTG AGTTTGAGTT TGCACTCTAC 
TCCCTGTGCT TCATCGCCAG GCCAGGCAAA GTGTGCCAGT TAAGCCTGGG AGGATATCCC 
TTAGCTGTCC GGACATATAC CTGGGACAAG TCCACCTATG GGAATGGCAA GAAGTACATC 
GCCACAGCCT ACATAGTGTC TTCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006016.1
CDS	160..1269
Translation	MRACISLVLAVLCGLAWAEDHKESEPLPQLEEETEEALASNLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_006025.3
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006025.3

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGAGGAC 
CACAAAGAGT CAGAGCCATT GCCACAGCTG GAGGAAGAGA CAGAAGAGGC CCTCGCCAGC 
AACTTGTACT CGGCACCCAC CTCCTGCCAG GGCCGCTGCT ACGAAGCCTT TGACAAGCAC 
CACCAATGTC ACTGCAATGC CCGCTGCCAA GAGTTTGGGA ACTGCTGCAA GGATTTTGAG 
AGCCTGTGTA GTGACCACGA GGTCTCCCAC AGCAGTGATG CCATAACAAA AGAGGAGATT 
CAGAGCATCT CTGAGAAGAT CTACAGGGCA GACACCAACA AAGCCCAGAA GGAAGACATC 
GTTCTCAATA GCCAAAACTG CATCTCCCCG TCAGAGACCA GAAACCAAGT GGATCGCTGC 
CCAAAGCCAC TCTTCACTTA TGTCAATGAG AAGCTGTTCT CCAAGCCCAC CTATGCAGCC 
TTCATCAACC TCCTCAACAA CTACCAGCGG GCAACAGGCC ATGGGGAGCA CTTCAGTGCC 
CAGGAGCTGG CCGAGCAGGA CGCCTTCCTC AGAGAGATCA TGAAGACAGC AGTCATGAAG 
GAGCTCTACA GCTTCCTCCA TCACCAGAAT CGCTATGGCT CAGAGCAAGA GTTTGTCGAT 
GACTTGAAGA ACATGTGGTT TGGGCTCTAT TCAAGAGGCA ATGAAGAGGG GGACTCGAGT 
GGCTTTGAAC ATGTCTTCTC AGGTGAGGTA AAAAAAGGCA AGGTTACTGG CTTCCATAAC 
TGGATCCGCT TCTACCTGGA GGAGAAGGAG GGTCTGGTTG ACTATTACAG TCACATCTAC 
GATGGGCCTT GGGATTCTTA CCCCGATGTG CTGGCAATGC AGTTCAACTG GGACGGCTAC 
TATAAGGAAG TGGGCTCTGC TTTCATCGGC AGCAGCCCTG AGTTTGAGTT TGCACTCTAC 
TCCCTGTGCT TCATCGCCAG GCCAGGCAAA GTGTGCCAGT TAAGCCTGGG AGGATATCCC 
TTAGCTGTCC GGACATATAC CTGGGACAAG TCCACCTATG GGAATGGCAA GAAGTACATC 
GCCACAGCCT ACATAGTGTC TTCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENDOU ( NM_001172440.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165911.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11593
Clone ID Related Accession (Same CDS sequence)	NM_001172440.1 , NM_001172440.2
Accession Version	NM_001172440.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC381238.1, AK300169.1, AC004241.2 and AI039727.1. Transcript Variant: This variant (3) lacks two alternate in-frame coding region segments, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK300169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGACTTG 
TACTCGGCAC CCACCTCCTG CCAGGGCCGC TGCTACGAAG CCTTTGACAA GCACCACCAA 
TGTCACTGCA ATGCCCGCTG CCAAGAGTTT GGGAACTGCT GCAAGGATTT TGAGAGCCTG 
TGTAGTGACC ACGAGGTCTC CCACAGCAGT GATGCCATAA CAAAAGAGGA GATTCAGAGC 
ATCTCTGAGA AGATCTACAG GGCAGACACC AACAAAGCCC AGAAGGAAGA CATCGTTCTC 
AATAGCCAAA ACTGCATCTC CCCGTCAGAG ACCAGAAACC AAGTGGATCG CTGCCCAAAG 
CCACTCTTCA CTTATGTCAA TGAGAAGCTG TTCTCCAAGC CCACCTATGC AGCCTTCATC 
AACCTCCTCA ACAACTACCA GCGGGCAACA GGCCATGGGG AGCACTTCAG TGCCCAGGAG 
CTGGCCGAGC AGGACGCCTT CCTCAGAGAG ATCATGAAGA CAGCAGTCAT GAAGGAGCTC 
TACAGCTTCC TCCATCACCA GAATCGCTAT GGCTCAGAGC AAGAGTTTGT CGATGACTTG 
AAGAACATGT GGTTTGGGCT CTATTCAAGA GGCAATGAAG AGGGGGACTC GAGTGGCTTT 
GAACATGTCT TCTCAGGTGA GGTAAAAAAA GGCAAGGTTA CTGGCTTCCA TAACTGGATC 
CGCTTCTACC TGGAGGAGAA GGAGGGTCTG GTTGACTATT ACAGTCACAT CTACGATGGG 
CCTTGGGATT CTTACCCCGA TGTGCTGGCA ATGCAGTTCA ACTGGGACGG CTACTATAAG 
GAAGTGGGCT CTGCTTTCAT CGGCAGCAGC CCTGAGTTTG AGTTTGCACT CTACTCCCTG 
TGCTTCATCG CCAGGCCAGG CAAAGTGTGC CAGTTAAGCC TGGGAGGATA TCCCTTAGCT 
GTCCGGACAT ATACCTGGGA CAAGTCCACC TATGGGAATG GCAAGAAGTA CATCGCCACA 
GCCTACATAG TGTCTTCCAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165911.1
CDS	160..1203
Translation	MRACISLVLAVLCGLAWADLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_001172440.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172440.1

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGACTTG 
TACTCGGCAC CCACCTCCTG CCAGGGCCGC TGCTACGAAG CCTTTGACAA GCACCACCAA 
TGTCACTGCA ATGCCCGCTG CCAAGAGTTT GGGAACTGCT GCAAGGATTT TGAGAGCCTG 
TGTAGTGACC ACGAGGTCTC CCACAGCAGT GATGCCATAA CAAAAGAGGA GATTCAGAGC 
ATCTCTGAGA AGATCTACAG GGCAGACACC AACAAAGCCC AGAAGGAAGA CATCGTTCTC 
AATAGCCAAA ACTGCATCTC CCCGTCAGAG ACCAGAAACC AAGTGGATCG CTGCCCAAAG 
CCACTCTTCA CTTATGTCAA TGAGAAGCTG TTCTCCAAGC CCACCTATGC AGCCTTCATC 
AACCTCCTCA ACAACTACCA GCGGGCAACA GGCCATGGGG AGCACTTCAG TGCCCAGGAG 
CTGGCCGAGC AGGACGCCTT CCTCAGAGAG ATCATGAAGA CAGCAGTCAT GAAGGAGCTC 
TACAGCTTCC TCCATCACCA GAATCGCTAT GGCTCAGAGC AAGAGTTTGT CGATGACTTG 
AAGAACATGT GGTTTGGGCT CTATTCAAGA GGCAATGAAG AGGGGGACTC GAGTGGCTTT 
GAACATGTCT TCTCAGGTGA GGTAAAAAAA GGCAAGGTTA CTGGCTTCCA TAACTGGATC 
CGCTTCTACC TGGAGGAGAA GGAGGGTCTG GTTGACTATT ACAGTCACAT CTACGATGGG 
CCTTGGGATT CTTACCCCGA TGTGCTGGCA ATGCAGTTCA ACTGGGACGG CTACTATAAG 
GAAGTGGGCT CTGCTTTCAT CGGCAGCAGC CCTGAGTTTG AGTTTGCACT CTACTCCCTG 
TGCTTCATCG CCAGGCCAGG CAAAGTGTGC CAGTTAAGCC TGGGAGGATA TCCCTTAGCT 
GTCCGGACAT ATACCTGGGA CAAGTCCACC TATGGGAATG GCAAGAAGTA CATCGCCACA 
GCCTACATAG TGTCTTCCAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENDOU ( NM_001172440.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165911.1 Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11593
Clone ID Related Accession (Same CDS sequence)	NM_001172440.1 , NM_001172440.2
Accession Version	NM_001172440.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	poly(U)-specific endoribonuclease isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC381238.1, AK300169.1, AC004241.2 and AI039727.1. On Jun 1, 2019 this sequence version replaced NM_001172440.1. Transcript Variant: This variant (3) lacks two alternate in-frame coding region segments, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK300169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGACTTG 
TACTCGGCAC CCACCTCCTG CCAGGGCCGC TGCTACGAAG CCTTTGACAA GCACCACCAA 
TGTCACTGCA ATGCCCGCTG CCAAGAGTTT GGGAACTGCT GCAAGGATTT TGAGAGCCTG 
TGTAGTGACC ACGAGGTCTC CCACAGCAGT GATGCCATAA CAAAAGAGGA GATTCAGAGC 
ATCTCTGAGA AGATCTACAG GGCAGACACC AACAAAGCCC AGAAGGAAGA CATCGTTCTC 
AATAGCCAAA ACTGCATCTC CCCGTCAGAG ACCAGAAACC AAGTGGATCG CTGCCCAAAG 
CCACTCTTCA CTTATGTCAA TGAGAAGCTG TTCTCCAAGC CCACCTATGC AGCCTTCATC 
AACCTCCTCA ACAACTACCA GCGGGCAACA GGCCATGGGG AGCACTTCAG TGCCCAGGAG 
CTGGCCGAGC AGGACGCCTT CCTCAGAGAG ATCATGAAGA CAGCAGTCAT GAAGGAGCTC 
TACAGCTTCC TCCATCACCA GAATCGCTAT GGCTCAGAGC AAGAGTTTGT CGATGACTTG 
AAGAACATGT GGTTTGGGCT CTATTCAAGA GGCAATGAAG AGGGGGACTC GAGTGGCTTT 
GAACATGTCT TCTCAGGTGA GGTAAAAAAA GGCAAGGTTA CTGGCTTCCA TAACTGGATC 
CGCTTCTACC TGGAGGAGAA GGAGGGTCTG GTTGACTATT ACAGTCACAT CTACGATGGG 
CCTTGGGATT CTTACCCCGA TGTGCTGGCA ATGCAGTTCA ACTGGGACGG CTACTATAAG 
GAAGTGGGCT CTGCTTTCAT CGGCAGCAGC CCTGAGTTTG AGTTTGCACT CTACTCCCTG 
TGCTTCATCG CCAGGCCAGG CAAAGTGTGC CAGTTAAGCC TGGGAGGATA TCCCTTAGCT 
GTCCGGACAT ATACCTGGGA CAAGTCCACC TATGGGAATG GCAAGAAGTA CATCGCCACA 
GCCTACATAG TGTCTTCCAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165911.1
CDS	78..1121
Translation	MRACISLVLAVLCGLAWADLYSAPTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST

Target ORF information:

RefSeq Version	NM_001172440.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172440.2

ORF Insert Sequence:

ATGAGGGCCT GCATCTCCCT GGTATTGGCC GTGCTGTGTG GCCTGGCCTG GGCTGACTTG 
TACTCGGCAC CCACCTCCTG CCAGGGCCGC TGCTACGAAG CCTTTGACAA GCACCACCAA 
TGTCACTGCA ATGCCCGCTG CCAAGAGTTT GGGAACTGCT GCAAGGATTT TGAGAGCCTG 
TGTAGTGACC ACGAGGTCTC CCACAGCAGT GATGCCATAA CAAAAGAGGA GATTCAGAGC 
ATCTCTGAGA AGATCTACAG GGCAGACACC AACAAAGCCC AGAAGGAAGA CATCGTTCTC 
AATAGCCAAA ACTGCATCTC CCCGTCAGAG ACCAGAAACC AAGTGGATCG CTGCCCAAAG 
CCACTCTTCA CTTATGTCAA TGAGAAGCTG TTCTCCAAGC CCACCTATGC AGCCTTCATC 
AACCTCCTCA ACAACTACCA GCGGGCAACA GGCCATGGGG AGCACTTCAG TGCCCAGGAG 
CTGGCCGAGC AGGACGCCTT CCTCAGAGAG ATCATGAAGA CAGCAGTCAT GAAGGAGCTC 
TACAGCTTCC TCCATCACCA GAATCGCTAT GGCTCAGAGC AAGAGTTTGT CGATGACTTG 
AAGAACATGT GGTTTGGGCT CTATTCAAGA GGCAATGAAG AGGGGGACTC GAGTGGCTTT 
GAACATGTCT TCTCAGGTGA GGTAAAAAAA GGCAAGGTTA CTGGCTTCCA TAACTGGATC 
CGCTTCTACC TGGAGGAGAA GGAGGGTCTG GTTGACTATT ACAGTCACAT CTACGATGGG 
CCTTGGGATT CTTACCCCGA TGTGCTGGCA ATGCAGTTCA ACTGGGACGG CTACTATAAG 
GAAGTGGGCT CTGCTTTCAT CGGCAGCAGC CCTGAGTTTG AGTTTGCACT CTACTCCCTG 
TGCTTCATCG CCAGGCCAGG CAAAGTGTGC CAGTTAAGCC TGGGAGGATA TCCCTTAGCT 
GTCCGGACAT ATACCTGGGA CAAGTCCACC TATGGGAATG GCAAGAAGTA CATCGCCACA 
GCCTACATAG TGTCTTCCAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The tumor marker human placental protein 11 is an endoribonuclease.
The Journal of biological chemistry283(50)34712-9(2008 Dec)
Laneve P,Gioia U,Ragno R,Altieri F,Di Franco C,Santini T,Arceci M,Bozzoni I,Caffarelli E

Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
The Journal of biological chemistry280(19)18996-9002(2005 May)
Gioia U,Laneve P,Dlakic M,Arceci M,Bozzoni I,Caffarelli E

Homology of placental protein 11 and pea seed albumin 2 with vitronectin.
Biochemical and biophysical research communications176(3)1000-6(1991 May)
Jenne D

Cloning and expression of a cDNA encoding human placental protein 11, a putative serine protease with diagnostic significance as a tumor marker.
DNA and cell biology9(4)243-50(1990 May)
Grundmann U,R?misch J,Siebold B,Bohn H,Amann E

Immunohistochemical detection of pregnancy-specific protein (SP1) and placenta-specific tissue proteins (PP5, PP10, PP11 and PP12) in ovarian adenocarcinomas.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine3(5-6)379-89(1982)
Inaba N,Ishige H,Ijichi M,Satoh N,Ohkawa R,Sekiya S,Shirotake S,Takamizawa H,Renk T,Bohn H

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ENDOU cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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