USP26 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	USP26
Entrez Gene ID	83844
Full Name	ubiquitin specific peptidase 26
General protein information	Preferred Names ubiquitin specific peptidase 26 Names ubiquitin carboxyl-terminal hydrolase 26 deubiquitinating enzyme 26 ubiquitin specific protease 26 ubiquitin thioesterase 26 ubiquitin thiolesterase 26 ubiquitin-specific processing protease 26
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq26.2
Summary	This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility. [provided by RefSeq, Jul 2008].
Disorder MIM:	300309

mRNA and Protein(s)

mRNA	Protein	Name
XM_017029892.1	XP_016885381.1	ubiquitin carboxyl-terminal hydrolase 26 isoform X1
NM_031907.1	NP_114113.1	ubiquitin carboxyl-terminal hydrolase 26
NM_031907.2	NP_114113.1	ubiquitin carboxyl-terminal hydrolase 26

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	USP26	XP_005641887.1
Bos taurus (cattle)	USP26	XP_005227578.1
Homo sapiens (human)	USP26	NP_114113.1
	USP26	XP_001097029.1
Rattus norvegicus (Norway rat)	Usp26	NP_001100418.1
Pan troglodytes (chimpanzee)	USP26	XP_003954133.1
Mus musculus (house mouse)	Usp26	NP_113565.2

Gene Ontology
Bibliography

Related articles in PubMed

USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Ning B, Zhao W, Qian C, Liu P, Li Q, Li W, Wang RF
Nature communications8(1)349(2017 08)

USP26 regulates TGF-? signaling by deubiquitinating and stabilizing SMAD7.
Kit Leng Lui S, Iyengar PV, Jaynes P, Isa ZFBA, Pang B, Tan TZ, Eichhorn PJA
EMBO reports18(5)797-808(2017 May)

The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.
Lahav-Baratz S, Kravtsova-Ivantsiv Y, Golan S, Ciechanover A
Biochemical and biophysical research communications482(1)106-111(2017 Jan)

Single nucleotide polymorphisms of USP26 in azoospermic men.
Luddi A, Crifasi L, Quagliarello A, Governini L, De Leo V, Piomboni P
Systems biology in reproductive medicine62(6)372-378(2016 Dec)

A Novel Missense Mutation in USP26 Gene Is Associated With Nonobstructive Azoospermia.
Ma Q, Li Y, Guo H, Li C, Chen J, Luo M, Jiang Z, Li H, Gui Y
Reproductive sciences (Thousand Oaks, Calif.)23(10)1434-41(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that USP26 interacts with PRC1 components chromobox (CBX)-containing proteins CBX4 and CBX6.
Title: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.

The interaction between USP26 and Mdm2, and the subsequent deubiquitination of Mdm2, serves, most probably to regulate Mdm2. Future therapeutic modalities that interfere with the association between USP26 and Mdm2 will be used to destabilize the ligase in malignancies where it is upregulated.
Title: The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.

identification in a normozoospermic man of a nonsense mutation (c.882C>A) which causes the production of a truncated protein, suggests a marginal role of USP26 in male spermatogenesis
Title: Single nucleotide polymorphisms of USP26 in azoospermic men.

A novel USP26 variant p.R344W is associated with nonobstructive azoospermia probably through affecting androgen receptor function.
Title: A Novel Missense Mutation in USP26 Gene Is Associated With Nonobstructive Azoospermia.

Evidence from both enzymatic and meta-analyses does not support a direct association between USP26 variants and male infertility
Title: Evidence from enzymatic and meta-analyses does not support a direct association between USP26 gene variants and male infertility.

The following USP26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the USP26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19444	NM_031907.2 Latest version!	Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu19444	XM_017029892.1 Latest version!	Homo sapiens ubiquitin specific peptidase 26 (USP26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu19444	NM_031907.1	Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

USP26 ( NM_031907.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_114113.1 Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.

Price & Availability↑

CloneID	OHu19444
Clone ID Related Accession (Same CDS sequence)	XM_017029892.1 , NM_031907.1 , NM_031907.2
Accession Version	NM_031907.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2742bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase 26
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF285593.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AF285593.1, BC069073.1 [ECO:0000345] ##Evidence-Data-END##

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114113.1
CDS	53..2794
Translation	MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE

Target ORF information:

RefSeq Version	NM_031907.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031907.1

ORF Insert Sequence:

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USP26 ( NM_031907.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114113.1 Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.

Price & Availability↑

CloneID	OHu19444
Clone ID Related Accession (Same CDS sequence)	XM_017029892.1 , NM_031907.1 , NM_031907.2
Accession Version	NM_031907.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2742bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase 26
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF285593.1 and Z81365.2. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_031907.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AF285593.1, BC101190.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END##

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114113.1
CDS	53..2794
Translation	MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE

Target ORF information:

RefSeq Version	NM_031907.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin specific peptidase 26 (USP26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031907.2

ORF Insert Sequence:

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USP26 ( XM_017029892.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885381.1 Homo sapiens ubiquitin specific peptidase 26 (USP26), transcript variant X1, mRNA.

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CloneID	OHu19444
Clone ID Related Accession (Same CDS sequence)	XM_017029892.1 , NM_031907.1 , NM_031907.2
Accession Version	XM_017029892.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2742bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase 26 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885381.1
CDS	139..2880
Translation	MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE

Target ORF information:

RefSeq Version	XM_017029892.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin specific peptidase 26 (USP26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029892.1

ORF Insert Sequence:

ATGGCTGCCC TATTCCTACG TGGTTTTGTC CAAATAGGGA ACTGCAAGAC TGGGATATCT 
AAGTCAAAAG AAGCATTCAT TGAAGCAGTG GAAAGAAAGA AGAAAGATAG ACTGGTGCTG 
TATTTCAAAA GTGGAAAATA TAGCACTTTT CGGCTAAGTG ATAATATTCA AAATGTAGTC 
CTTAAATCCT ATAGAGGAAA CCAAAATCAC CTGCATTTAA CTTTACAAAA TAATAATGGC 
TTGTTTATTG AAGGATTATC CTCCACAGAT GCTGAACAAT TGAAGATATT CTTGGACAGA 
GTTCATCAAA ACGAGGTTCA GCCACCTGTG AGACCTGGTA AGGGTGGGAG TGTCTTTTCT 
AGCACAACAC AGAAGGAAAT CAACAAAACT TCATTCCACA AAGTTGATGA GAAATCAAGT 
AGCAAATCTT TTGAGATAGC AAAAGGAAGT GGGACAGGTG TCCTTCAGAG GATGCCTTTG 
CTTACATCAA AATTGACACT TACTTGCGGA GAGTTATCAG AAAATCAGCA CAAGAAGAGG 
AAAAGAATGC TCTCATCTAG CTCAGAGATG AATGAGGAAT TCTTGAAAGA AAATAATTCT 
GTAGAATACA AGAAATCCAA GGCAGATTGT TCGAGGTGTG TAAGCTATAA TCGAGAGAAA 
CAATTGAAGT TAAAAGAGTT AGAAGAGAAT AAGAAATTGG AATGTGAATC TTCATGCATC 
ATGAACGCCA CTGGAAATCC TTACCTAGAT GACATTGGTC TTCTCCAAGC TCTCACTGAG 
AAAATGGTTT TGGTATTTCT GTTACAACAA GGGTATAGTG ACGGTTACAC AAAGTGGGAT 
AAATTAAAAC TATTTTTTGA ATTATTTCCA GAGAAAATAT GCCACGGCCT CCCCAATTTG 
GGAAACACCT GTTATATGAA TGCAGTGTTA CAGTCTCTAC TTTCAATCCC ATCGTTTGCT 
GATGATTTAC TTAATCAGAG TTTCCCATGG GGTAAAATTC CCCTTAATGC TCTTACCATG 
TGCTTGGCAC GGCTACTTTT TTTTAAAGAT ACCTATAATA TAGAAATCAA GGAGATGTTA 
CTCTTGAATC TTAAAAAGGC CATTTCAGCA GCTGCAGAGA TATTCCATGG CAATGCACAG 
AACGATGCTC ATGAGTTTTT AGCTCACTGT TTAGATCAAC TGAAAGATAA CATGGAAAAA 
CTCAACACAA TTTGGAAGCC TAAAAGTGAA TTTGGGGAAG ATAATTTTCC TAAACAGGTT 
TTTGCTGATG ATCCTGACAC CAGTGGGTTT TCTTGCCCTG TCATTACTAA TTTTGAGTTA 
GAGTTGTTGC ACTCCATTGC TTGTAAAGCT TGTGGTCAGG TTATTCTCAA GACAGAACTG 
AATAATTACC TCTCCATCAA CCTTCCCCAA AGAATAAAAG CACATCCTTC ATCTATTCAG 
TCTACTTTTG ATCTTTTTTT TGGAGCAGAA GAGCTTGAGT ATAAATGTGC AAAATGTGAG 
CACAAGACTT CCGTTGGAGT GCACTCATTC AGTAGGCTAC CTAGAATCCT TATTGTTCAC 
CTCAAACGCT ATAGCTTGAA TGAGTTTTGT GCATTAAAGA AGAATGACCA GGAAGTCATC 
ATTTCCAAAT ATTTAAAGGT GTCTTCTCAT TGCAATGAAG GCACCAGACC ACCTCTTCCC 
TTGAGTGAGG ATGGAGAAAT TACAGATTTC CAATTATTAA AAGTTATTCG AAAGATGACT 
TCTGGAAACA TCAGTGTATC ATGGCCTGCA ACAAAGGAAT CCAAAGATAT CCTGGCTCCA 
CACATTGGAT CAGATAAGGA GTCTGAACAA AAAAAAGGCC AGACAGTCTT TAAAGGGGCA 
AGCAGAAGAC AGCAGCAAAA GTACCTTGGA AAAAATTCTA AACCAAATGA GCTAGAATCT 
GTATACTCAG GAGATCGAGC ATTCATTGAA AAAGAACCGT TAGCTCACTT AATGACGTAT 
CTGGAAGATA CCTCACTTTG TCAGTTCCAC AAAGCTGGAG GTAAACCTGC CAGCAGCCCA 
GGCACACCTC TCTCAAAAGT TGACTTTCAA ACAGTGCCCG AAAATCCAAA ACGAAAGAAA 
TATGTGAAAA CCAGTAAGTT TGTAGCTTTT GATAGGATTA TCAATCCTAC TAAAGATTTG 
TATGAAGATA AAAATATCAG AATTCCAGAA AGATTCCAAA AAGTGTCTGA ACAGACTCAG 
CAGTGTGACG GTATGAGAAT CTGTGAACAA GCCCCTCAGC AGGCACTGCC TCAAAGCTTT 
CCAAAGCCAG GCACCCAGGG GCACACAAAG AACCTCCTAA GACCTACAAA ATTAAATCTA 
CAGAAGTCTA ACAGGAATTC CCTACTTGCA CTGGGTTCCA ATAAGAATCC AAGAAACAAA 
GACATTTTAG ATAAGATAAA ATCTAAAGCC AAGGAAACAA AAAGAAATGA TGATAAGGGA 
GATCATACCT ACCGGCTCAT TAGTGTTGTC AGCCATCTTG GGAAGACTCT AAAGTCAGGC 
CATTATATCT GTGATGCCTA TGACTTTGAG AAACAGATCT GGTTCACTTA CGATGATATG 
CGGGTGTTAG GTATCCAGGA GGCCCAGATG CAGGAGGATA GGCGTTGCAC TGGGTACATC 
TTCTTTTACA TGCATAATGA GATCTTTGAA GAGATGTTGA AAAGAGAAGA GAATGCCCAG 
CTTAATAGCA AGGAGGTAGA GGAGACCCTT CAGAAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Nature communications8(1)349(2017 08)
Ning B,Zhao W,Qian C,Liu P,Li Q,Li W,Wang RF

USP26 regulates TGF-? signaling by deubiquitinating and stabilizing SMAD7.
EMBO reports18(5)797-808(2017 May)
Kit Leng Lui S,Iyengar PV,Jaynes P,Isa ZFBA,Pang B,Tan TZ,Eichhorn PJA

The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.
Biochemical and biophysical research communications482(1)106-111(2017 Jan)
Lahav-Baratz S,Kravtsova-Ivantsiv Y,Golan S,Ciechanover A

Single nucleotide polymorphisms of USP26 in azoospermic men.
Systems biology in reproductive medicine62(6)372-378(2016 Dec)
Luddi A,Crifasi L,Quagliarello A,Governini L,De Leo V,Piomboni P

A Novel Missense Mutation in USP26 Gene Is Associated With Nonobstructive Azoospermia.
Reproductive sciences (Thousand Oaks, Calif.)23(10)1434-41(2016 10)
Ma Q,Li Y,Guo H,Li C,Chen J,Luo M,Jiang Z,Li H,Gui Y

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USP26 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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