XRCC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XRCC2
Entrez Gene ID	7516
Full Name	X-ray repair cross complementing 2
Synonyms	FANCU
General protein information	Preferred Names X-ray repair cross complementing 2 Names DNA repair protein XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 X-ray repair cross-complementing protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.1
Summary	This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008].
Disorder MIM:	600375
Disorder Html:	?Fanconi anemia, complementation group U, 617247 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005431.1	NP_005422.1	DNA repair protein XRCC2
NM_005431.2	NP_005422.1	DNA repair protein XRCC2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	XRCC2	XP_532771.3
Xenopus tropicalis (tropical clawed frog)	xrcc2	XP_002932541.2
Homo sapiens (human)	XRCC2	NP_005422.1
Rattus norvegicus (Norway rat)	Xrcc2	NP_001102685.1
	XRCC2	XP_001108141.1
Danio rerio (zebrafish)	LOC553395	XP_685091.2
Pan troglodytes (chimpanzee)	XRCC2	XP_001140134.1
Bos taurus (cattle)	XRCC2	NP_001095824.1
Mus musculus (house mouse)	Xrcc2	NP_065595.2
Gallus gallus (chicken)	XRCC2	XP_418543.3

Gene Ontology

The following XRCC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XRCC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18850	NM_005431.2 Latest version!	Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu18850	NM_005431.1	Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XRCC2 ( NM_005431.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_005422.1 Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.

Price & Availability↑

CloneID	OHu18850
Clone ID Related Accession (Same CDS sequence)	NM_005431.1 , NM_005431.2
Accession Version	NM_005431.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	DNA repair protein XRCC2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF035587.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF035587.1, SRR1163655.654669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGTAGTG CCTTCCATAG GGCTGAGTCT GGGACCGAGC TCCTTGCCCG ACTTGAAGGT 
AGAAGTTCCT TGAAAGAAAT AGAACCAAAT CTGTTTGCTG ATGAAGATTC ACCTGTGCAT 
GGTGATATTC TTGAATTTCA TGGCCCAGAA GGAACAGGAA AAACAGAAAT GCTTTATCAC 
CTAACAGCAC GATGTATACT TCCCAAATCA GAAGGTGGCC TGGAAGTAGA AGTCTTATTT 
ATTGATACAG ATTACCACTT TGATATGCTC CGGCTAGTTA CAATTCTTGA GCACAGACTA 
TCCCAAAGCT CTGAAGAAAT AATCAAATAC TGCCTGGGAA GATTTTTTTT GGTGTACTGC 
AGTAGTAGCA CCCACTTACT TCTTACACTT TACTCACTAG AAAGTATGTT TTGTAGTCAC 
CCATCTCTCT GCCTTTTGAT TTTGGATAGC CTGTCAGCTT TTTACTGGAT AGACCGCGTC 
AATGGAGGAG AAAGTGTGAA CTTACAGGAG TCTACTCTGA GGAAATGTTC TCAGTGCTTA 
GAGAAGCTTG TAAATGACTA TCGCCTGGTT CTTTTTGCAA CGACACAAAC TATAATGCAG 
AAAGCCTCGA GCTCATCAGA AGAACCTTCT CATGCCTCTC GACGACTGTG TGATGTGGAC 
ATAGACTACA GACCTTATCT CTGTAAGGCA TGGCAGCAAC TGGTGAAGCA CAGGATGTTT 
TTCTCCAAAC AAGATGATTC TCAAAGCAGC AACCAATTTT CATTAGTTTC ACGTTGTTTA 
AAAAGTAACA GTTTAAAAAA ACATTTTTTT ATTATTGGAG AAAGTGGGGT TGAATTTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005422.1
CDS	87..929
Translation	MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC

Target ORF information:

RefSeq Version	NM_005431.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005431.1

ORF Insert Sequence:

ATGTGTAGTG CCTTCCATAG GGCTGAGTCT GGGACCGAGC TCCTTGCCCG ACTTGAAGGT 
AGAAGTTCCT TGAAAGAAAT AGAACCAAAT CTGTTTGCTG ATGAAGATTC ACCTGTGCAT 
GGTGATATTC TTGAATTTCA TGGCCCAGAA GGAACAGGAA AAACAGAAAT GCTTTATCAC 
CTAACAGCAC GATGTATACT TCCCAAATCA GAAGGTGGCC TGGAAGTAGA AGTCTTATTT 
ATTGATACAG ATTACCACTT TGATATGCTC CGGCTAGTTA CAATTCTTGA GCACAGACTA 
TCCCAAAGCT CTGAAGAAAT AATCAAATAC TGCCTGGGAA GATTTTTTTT GGTGTACTGC 
AGTAGTAGCA CCCACTTACT TCTTACACTT TACTCACTAG AAAGTATGTT TTGTAGTCAC 
CCATCTCTCT GCCTTTTGAT TTTGGATAGC CTGTCAGCTT TTTACTGGAT AGACCGCGTC 
AATGGAGGAG AAAGTGTGAA CTTACAGGAG TCTACTCTGA GGAAATGTTC TCAGTGCTTA 
GAGAAGCTTG TAAATGACTA TCGCCTGGTT CTTTTTGCAA CGACACAAAC TATAATGCAG 
AAAGCCTCGA GCTCATCAGA AGAACCTTCT CATGCCTCTC GACGACTGTG TGATGTGGAC 
ATAGACTACA GACCTTATCT CTGTAAGGCA TGGCAGCAAC TGGTGAAGCA CAGGATGTTT 
TTCTCCAAAC AAGATGATTC TCAAAGCAGC AACCAATTTT CATTAGTTTC ACGTTGTTTA 
AAAAGTAACA GTTTAAAAAA ACATTTTTTT ATTATTGGAG AAAGTGGGGT TGAATTTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC2 ( NM_005431.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005422.1 Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.

Price & Availability↑

CloneID	OHu18850
Clone ID Related Accession (Same CDS sequence)	NM_005431.1 , NM_005431.2
Accession Version	NM_005431.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	DNA repair protein XRCC2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF035587.1 and AC003109.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005431.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK313607.1, AF035587.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000359321.2/ ENSP00000352271.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGTAGTG CCTTCCATAG GGCTGAGTCT GGGACCGAGC TCCTTGCCCG ACTTGAAGGT 
AGAAGTTCCT TGAAAGAAAT AGAACCAAAT CTGTTTGCTG ATGAAGATTC ACCTGTGCAT 
GGTGATATTC TTGAATTTCA TGGCCCAGAA GGAACAGGAA AAACAGAAAT GCTTTATCAC 
CTAACAGCAC GATGTATACT TCCCAAATCA GAAGGTGGCC TGGAAGTAGA AGTCTTATTT 
ATTGATACAG ATTACCACTT TGATATGCTC CGGCTAGTTA CAATTCTTGA GCACAGACTA 
TCCCAAAGCT CTGAAGAAAT AATCAAATAC TGCCTGGGAA GATTTTTTTT GGTGTACTGC 
AGTAGTAGCA CCCACTTACT TCTTACACTT TACTCACTAG AAAGTATGTT TTGTAGTCAC 
CCATCTCTCT GCCTTTTGAT TTTGGATAGC CTGTCAGCTT TTTACTGGAT AGACCGCGTC 
AATGGAGGAG AAAGTGTGAA CTTACAGGAG TCTACTCTGA GGAAATGTTC TCAGTGCTTA 
GAGAAGCTTG TAAATGACTA TCGCCTGGTT CTTTTTGCAA CGACACAAAC TATAATGCAG 
AAAGCCTCGA GCTCATCAGA AGAACCTTCT CATGCCTCTC GACGACTGTG TGATGTGGAC 
ATAGACTACA GACCTTATCT CTGTAAGGCA TGGCAGCAAC TGGTGAAGCA CAGGATGTTT 
TTCTCCAAAC AAGATGATTC TCAAAGCAGC AACCAATTTT CATTAGTTTC ACGTTGTTTA 
AAAAGTAACA GTTTAAAAAA ACATTTTTTT ATTATTGGAG AAAGTGGGGT TGAATTTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005422.1
CDS	63..905
Translation	MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC

Target ORF information:

RefSeq Version	NM_005431.2
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 2 (XRCC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005431.2

ORF Insert Sequence:

ATGTGTAGTG CCTTCCATAG GGCTGAGTCT GGGACCGAGC TCCTTGCCCG ACTTGAAGGT 
AGAAGTTCCT TGAAAGAAAT AGAACCAAAT CTGTTTGCTG ATGAAGATTC ACCTGTGCAT 
GGTGATATTC TTGAATTTCA TGGCCCAGAA GGAACAGGAA AAACAGAAAT GCTTTATCAC 
CTAACAGCAC GATGTATACT TCCCAAATCA GAAGGTGGCC TGGAAGTAGA AGTCTTATTT 
ATTGATACAG ATTACCACTT TGATATGCTC CGGCTAGTTA CAATTCTTGA GCACAGACTA 
TCCCAAAGCT CTGAAGAAAT AATCAAATAC TGCCTGGGAA GATTTTTTTT GGTGTACTGC 
AGTAGTAGCA CCCACTTACT TCTTACACTT TACTCACTAG AAAGTATGTT TTGTAGTCAC 
CCATCTCTCT GCCTTTTGAT TTTGGATAGC CTGTCAGCTT TTTACTGGAT AGACCGCGTC 
AATGGAGGAG AAAGTGTGAA CTTACAGGAG TCTACTCTGA GGAAATGTTC TCAGTGCTTA 
GAGAAGCTTG TAAATGACTA TCGCCTGGTT CTTTTTGCAA CGACACAAAC TATAATGCAG 
AAAGCCTCGA GCTCATCAGA AGAACCTTCT CATGCCTCTC GACGACTGTG TGATGTGGAC 
ATAGACTACA GACCTTATCT CTGTAAGGCA TGGCAGCAAC TGGTGAAGCA CAGGATGTTT 
TTCTCCAAAC AAGATGATTC TCAAAGCAGC AACCAATTTT CATTAGTTTC ACGTTGTTTA 
AAAAGTAACA GTTTAAAAAA ACATTTTTTT ATTATTGGAG AAAGTGGGGT TGAATTTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.