LGALS7B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LGALS7B
Entrez Gene ID	653499
Full Name	galectin 7B
Synonyms	GAL7,Gal-7,HKL-14,LGALS7,PI7
General protein information	Preferred Names galectin 7B Names galectin-7 keratinocyte lectin 14 lectin galactoside-binding soluble 7 lectin, galactoside-binding, soluble, 7B p53-induced gene 1 protein p53-induced protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008].
Disorder MIM:	617139

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042507.3	NP_001035972.1	galectin-7
NM_001042507.4	NP_001035972.1	galectin-7

Pathways from BioSystems

Homologies

Homo sapiens (human)	LGALS7	NP_002298.1
	LGALS7	XP_001083444.1
Canis lupus familiaris (dog)	LGALS7B	XP_003432634.2
Homo sapiens (human)	LGALS7B	NP_001035972.1
Canis lupus familiaris (dog)	LOC100855989	XP_003638881.2
Bos taurus (cattle)	LGALS7	XP_002695021.1
Bos taurus (cattle)	LGALS7B	XP_002695023.2
Mus musculus (house mouse)	Lgals7	NP_032522.2
Rattus norvegicus (Norway rat)	Lgals7	NP_072104.2

Gene Ontology
Bibliography

Related articles in PubMed

Galectin-7 serum levels are altered prior to the onset of pre-eclampsia.
Menkhorst E, Koga K, Van Sinderen M, Dimitriadis E
Placenta35(4)281-5(2014 Apr)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas.
Saussez S, Decaestecker C, Lorfevre F, Chevalier D, Mortuaire G, Kaltner H, Andr? S, Toubeau G, Gabius HJ, Leroy X
Histopathology52(4)483-93(2008 Mar)

Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancer.
Saussez S, Cucu DR, Decaestecker C, Chevalier D, Kaltner H, Andr? S, Wacreniez A, Toubeau G, Camby I, Gabius HJ, Kiss R
Annals of surgical oncology13(7)999-1009(2006 Jul)

Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells.
Kopitz J, Andr? S, von Reitzenstein C, Versluis K, Kaltner H, Pieters RJ, Wasano K, Kuwabara I, Liu FT, Cantz M, Heck AJ, Gabius HJ
Oncogene22(40)6277-88(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

serum concentration was significantly elevated in women (weeks 10-12 and 17-20) who subsequently developed pre-eclampsia
Title: Galectin-7 serum levels are altered prior to the onset of pre-eclampsia.

An association was seen between the level of presence of galectins-1 and -7 and neoplastic progression of hypopharyngeal and laryngeal squamous cell carcinomas.
Title: Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas.

The following LGALS7B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LGALS7B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09112	NM_001042507.4 Latest version!	Homo sapiens galectin 7B (LGALS7B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu09112	NM_001042507.3	Homo sapiens galectin 7B (LGALS7B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LGALS7B ( NM_001042507.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035972.1 Homo sapiens galectin 7B (LGALS7B), mRNA.

Price & Availability↑

CloneID	OHu09112
Clone ID Related Accession (Same CDS sequence)	NM_001042507.3 , NM_001042507.4
Accession Version	NM_001042507.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	galectin-7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L07769.1, AW015224.1 and BC042911.2. On Jul 30, 2008 this sequence version replaced NM_001042507.2. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACG TCCCCCACAA GTCCTCACTG CCCGAGGGCA TCCGCCCTGG CACGGTGCTG 
AGAATTCGCG GCTTGGTTCC TCCCAATGCC AGCAGGTTCC ATGTAAACCT GCTGTGCGGG 
GAGGAGCAGG GCTCCGATGC CGCCCTGCAT TTCAACCCCC GGCTGGACAC GTCGGAGGTG 
GTCTTCAACA GCAAGGAGCA AGGCTCCTGG GGCCGCGAGG AGCGCGGGCC GGGCGTTCCT 
TTCCAGCGCG GGCAGCCCTT CGAGGTGCTC ATCATCGCGT CAGACGACGG CTTCAAGGCC 
GTGGTTGGGG ACGCCCAGTA CCACCACTTC CGCCACCGCC TGCCGCTGGC GCGCGTGCGC 
CTGGTGGAGG TGGGCGGGGA CGTGCAGCTG GACTCCGTGA GGATCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035972.1
CDS	18..428
Translation	MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF

Target ORF information:

RefSeq Version	NM_001042507.3
Organism	Homo sapiens(human)
Definition	Homo sapiens galectin 7B (LGALS7B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042507.3

ORF Insert Sequence:

ATGTCCAACG TCCCCCACAA GTCCTCACTG CCCGAGGGCA TCCGCCCTGG CACGGTGCTG 
AGAATTCGCG GCTTGGTTCC TCCCAATGCC AGCAGGTTCC ATGTAAACCT GCTGTGCGGG 
GAGGAGCAGG GCTCCGATGC CGCCCTGCAT TTCAACCCCC GGCTGGACAC GTCGGAGGTG 
GTCTTCAACA GCAAGGAGCA AGGCTCCTGG GGCCGCGAGG AGCGCGGGCC GGGCGTTCCT 
TTCCAGCGCG GGCAGCCCTT CGAGGTGCTC ATCATCGCGT CAGACGACGG CTTCAAGGCC 
GTGGTTGGGG ACGCCCAGTA CCACCACTTC CGCCACCGCC TGCCGCTGGC GCGCGTGCGC 
CTGGTGGAGG TGGGCGGGGA CGTGCAGCTG GACTCCGTGA GGATCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGALS7B ( NM_001042507.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035972.1 Homo sapiens galectin 7B (LGALS7B), mRNA.

Price & Availability↑

CloneID	OHu09112
Clone ID Related Accession (Same CDS sequence)	NM_001042507.3 , NM_001042507.4
Accession Version	NM_001042507.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	galectin-7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC022144.8, L07769.1, AW015224.1 and BC042911.2. On May 17, 2019 this sequence version replaced NM_001042507.3. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000314980.5/ ENSP00000313571.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACG TCCCCCACAA GTCCTCACTG CCCGAGGGCA TCCGCCCTGG CACGGTGCTG 
AGAATTCGCG GCTTGGTTCC TCCCAATGCC AGCAGGTTCC ATGTAAACCT GCTGTGCGGG 
GAGGAGCAGG GCTCCGATGC CGCCCTGCAT TTCAACCCCC GGCTGGACAC GTCGGAGGTG 
GTCTTCAACA GCAAGGAGCA AGGCTCCTGG GGCCGCGAGG AGCGCGGGCC GGGCGTTCCT 
TTCCAGCGCG GGCAGCCCTT CGAGGTGCTC ATCATCGCGT CAGACGACGG CTTCAAGGCC 
GTGGTTGGGG ACGCCCAGTA CCACCACTTC CGCCACCGCC TGCCGCTGGC GCGCGTGCGC 
CTGGTGGAGG TGGGCGGGGA CGTGCAGCTG GACTCCGTGA GGATCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035972.1
CDS	28..438
Translation	MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF

Target ORF information:

RefSeq Version	NM_001042507.4
Organism	Homo sapiens(human)
Definition	Homo sapiens galectin 7B (LGALS7B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042507.4

ORF Insert Sequence:

ATGTCCAACG TCCCCCACAA GTCCTCACTG CCCGAGGGCA TCCGCCCTGG CACGGTGCTG 
AGAATTCGCG GCTTGGTTCC TCCCAATGCC AGCAGGTTCC ATGTAAACCT GCTGTGCGGG 
GAGGAGCAGG GCTCCGATGC CGCCCTGCAT TTCAACCCCC GGCTGGACAC GTCGGAGGTG 
GTCTTCAACA GCAAGGAGCA AGGCTCCTGG GGCCGCGAGG AGCGCGGGCC GGGCGTTCCT 
TTCCAGCGCG GGCAGCCCTT CGAGGTGCTC ATCATCGCGT CAGACGACGG CTTCAAGGCC 
GTGGTTGGGG ACGCCCAGTA CCACCACTTC CGCCACCGCC TGCCGCTGGC GCGCGTGCGC 
CTGGTGGAGG TGGGCGGGGA CGTGCAGCTG GACTCCGTGA GGATCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Galectin-7 serum levels are altered prior to the onset of pre-eclampsia.
Placenta35(4)281-5(2014 Apr)
Menkhorst E,Koga K,Van Sinderen M,Dimitriadis E

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas.
Histopathology52(4)483-93(2008 Mar)
Saussez S,Decaestecker C,Lorfevre F,Chevalier D,Mortuaire G,Kaltner H,Andr? S,Toubeau G,Gabius HJ,Leroy X

Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancer.
Annals of surgical oncology13(7)999-1009(2006 Jul)
Saussez S,Cucu DR,Decaestecker C,Chevalier D,Kaltner H,Andr? S,Wacreniez A,Toubeau G,Camby I,Gabius HJ,Kiss R

Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells.
Oncogene22(40)6277-88(2003 Sep)
Kopitz J,Andr? S,von Reitzenstein C,Versluis K,Kaltner H,Pieters RJ,Wasano K,Kuwabara I,Liu FT,Cantz M,Heck AJ,Gabius HJ