gRNAs
The following USP17L4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the USP17L4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu00267 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256874.1 | |
| Accession Version | NM_001256874.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-08 | |
| Organism | Homo sapiens(human) | |
| Product | inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4 | |
| Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AC130360.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: This CCDS representation lacks full-length human transcript support. Its representation is therefore inferred, but it is supported by paralogous transcripts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology MANE Ensembl match :: ENST00000526929.1/ ENSP00000485243.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## | |
1 | ATGGGGGACG ACTCACTCTA CTTGGGAGGT GAGTGGCAGT TCAACCACTT TTCAAAACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243803.1 |
| CDS | 1..1593 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001256874.1 |
1 | ATGGGGGACG ACTCACTCTA CTTGGGAGGT GAGTGGCAGT TCAACCACTT TTCAAAACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu106328 | |
| Clone ID Related Accession (Same CDS sequence) | XM_024452664.1 | |
| Accession Version | XM_024452664.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-06-12 | |
| Organism | Homo sapiens(human) | |
| Product | inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_018654717.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## | |
1 | ATGGAAGACG ACTCACTCTA TTTGGGAGGT GACTGGCAGT TCAATCACTT TTCAAAACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_024308432.1 |
| CDS | 351..1943 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_024452664.1 |
1 | ATGGAAGACG ACTCACTCTA TTTGGGAGGT GACTGGCAGT TCAATCACTT TTCAAAACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. |
The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility. |
Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme. |
The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression. |
The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster. |
