CDH22 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDH22
Entrez Gene ID	64405
Full Name	cadherin 22
Synonyms	C20orf25,dJ998H6.1
General protein information	Preferred Names cadherin 22 Names cadherin-22 PB-cadherin cadherin 22, type 2 cadherin-like 22 ortholog of rat PB-cadherin pituitary and brain cadherin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12
Summary	This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008].
Disorder MIM:	609920

mRNA and Protein(s)

mRNA	Protein	Name
XM_011528994.2	XP_011527296.1	cadherin-22 isoform X1
NM_021248.2	NP_067071.1	cadherin-22 precursor
XM_024451967.1	XP_024307735.1	cadherin-22 isoform X3
NM_021248.3	NP_067071.1	cadherin-22 precursor
XM_011528995.1	XP_011527297.1	cadherin-22 isoform X2
XM_024451966.1	XP_024307734.1	cadherin-22 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CDH22	XP_525344.4
Bos taurus (cattle)	CDH22	NP_001192705.1
Canis lupus familiaris (dog)	CDH22	XP_543030.2
Xenopus tropicalis (tropical clawed frog)	cdh22	XP_002932572.2
Homo sapiens (human)	CDH22	NP_067071.1
Mus musculus (house mouse)	Cdh22	NP_778153.2
Rattus norvegicus (Norway rat)	Cdh22	NP_062034.2
Gallus gallus (chicken)	CDH22	XP_417477.3

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.
Kelly NJ, Varga JFA, Specker EJ, Romeo CM, Coomber BL, Uniacke J
Oncogene(2017 Oct)

Mart?n-S?nchez E, Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, C?rdoba A, Vicente-Garc?a F, Blanco-Luquin I, De La Cruz S, Aramendia A, Guerrero-Setas D
Clinical epigenetics97(2017)

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Lauc G, Huffman JE, Pu?i? M, Zgaga L, Adamczyk B, Mu?ini? A, Novokmet M, Pola?ek O, Gornik O, Kri?ti? J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kol?i? I, Luki? IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I
PLoS genetics9(1)e1003225(2013)

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
Lewis JP, Palmer ND, Ellington JB, Divers J, Ng MC, Lu L, Langefeld CD, Freedman BI, Bowden DW
Genomics96(4)211-9(2010 Oct)

Over-expression of CDH22 is associated with tumor progression in colorectal cancer.
Zhou J, Li J, Chen J, Liu Y, Gao W, Ding Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine30(3)130-40(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results present evidence that CDH22 is hypermethylated and its expression is downregulated in breast cancer.

Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.

PRL-3 promoted downregulation of CDH22 expression.
Title: PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly.

Our results reveal for the first time a new role of CDH22 in progression of colorectal cancer.
Title: Over-expression of CDH22 is associated with tumor progression in colorectal cancer.

Observational study of gene-disease association. (HuGE Navigator)
Title: Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

The following CDH22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDH22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27670	NM_021248.3 Latest version!	Homo sapiens cadherin 22 (CDH22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27670	XM_011528994.2 Latest version!	Homo sapiens cadherin 22 (CDH22), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu105153	XM_024451967.1 Latest version!	Homo sapiens cadherin 22 (CDH22), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu53088	XM_011528995.1 Latest version!	Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu53088	XM_024451966.1 Latest version!	Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu27670	NM_021248.2	Homo sapiens cadherin 22 (CDH22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDH22 ( NM_021248.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_067071.1 Homo sapiens cadherin 22 (CDH22), mRNA.

Price & Availability↑

CloneID	OHu27670
Clone ID Related Accession (Same CDS sequence)	XM_011528994.2 , NM_021248.2 , NM_021248.3
Accession Version	NM_021248.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2487bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-03
Organism	Homo sapiens(human)
Product	cadherin-22 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289584.1, BC039056.1 and BQ102264.1. On Jan 29, 2013 this sequence version replaced NM_021248.1. ##Evidence-Data-START## Transcript exon combination :: AK289584.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067071.1
CDS	644..3130
Translation	MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS

Target ORF information:

RefSeq Version	NM_021248.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021248.2

ORF Insert Sequence:

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH22 ( NM_021248.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067071.1 Homo sapiens cadherin 22 (CDH22), mRNA.

Price & Availability↑

CloneID	OHu27670
Clone ID Related Accession (Same CDS sequence)	XM_011528994.2 , NM_021248.2 , NM_021248.3
Accession Version	NM_021248.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2487bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	cadherin-22 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289584.1, BC039056.1 and BQ102264.1. On May 17, 2019 this sequence version replaced NM_021248.2. ##Evidence-Data-START## Transcript exon combination :: AK289584.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000537909.4/ ENSP00000437790.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067071.1
CDS	644..3130
Translation	MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS

Target ORF information:

RefSeq Version	NM_021248.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021248.3

ORF Insert Sequence:

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH22 ( XM_011528994.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527296.1 Homo sapiens cadherin 22 (CDH22), transcript variant X1, mRNA.

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CloneID	OHu27670
Clone ID Related Accession (Same CDS sequence)	XM_011528994.2 , NM_021248.2 , NM_021248.3
Accession Version	XM_011528994.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2487bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cadherin-22 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528994.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527296.1
CDS	603..3089
Translation	MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS

Target ORF information:

RefSeq Version	XM_011528994.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528994.2

ORF Insert Sequence:

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGACAATCA TGCACAGCTA 
TCCCGGGCAT CCCTAAGGAT CCGAATCCTG GATGTGAACG ACAATCCCCC AGAACTGGCC 
ACACCCTACG AGGCAGCTGT ATGCGAGGAT GCCAAGCCAG GCCAGCTCAT CCAGACCATC 
AGCGTGGTGG ACAGAGACGA GCCCCAAGGC GGGCACCGCT TCTATTTCCG CCTGGTGCCT 
GAAGCTCCCA GCAACCCTCA TTTCTCTCTG CTTGACATCC AAGACAACAC CGCTGCAGTG 
CACACGCAGC ACGTGGGCTT CAACCGGCAG GAGCAGGACG TGTTCTTCCT GCCCATCCTG 
GTGGTAGACA GTGGGCCGCC CACACTGAGC AGCACAGGCA CGCTCACCAT CCGCATCTGT 
GGCTGCGACA GCTCCGGCAC CATCCAGTCC TGCAACACCA CGGCCTTTGT CATGGCCGCC 
TCCCTCAGCC CCGGCGCCCT CATCGCCCTC TTGGTCTGCG TTCTCATCCT GGTTGTGCTG 
GTGCTGCTGA TCCTCACCCT CAGGCGCCAC CACAAGAGCC ACCTGAGCTC GGACGAGGAT 
GAAGACATGC GGGACAACGT CATCAAATAC AACGACGAAG GCGGCGGCGA GCAGGACACC 
GAAGCCTACG ACATGTCGGC GCTGCGGAGC CTCTACGACT TCGGCGAGCT CAAGGGCGGC 
GACGGGGGCG GCAGCGCGGG CGGGGGAGCG GGCGGGGGCT CGGGCGGGGG CGCGGGCAGC 
CCCCCGCAGG CCCACCTGCC CTCCGAGCGC CACTCGCTGC CGCAGGGGCC GCCGAGCCCC 
GAGCCAGACT TCTCAGTGTT CAGGGACTTC ATCAGCCGCA AGGTGGCACT GGCGGACGGG 
GACCTGTCGG TGCCGCCCTA CGACGCCTTC CAGACCTACG CCTTCGAGGG CGCGGACTCG 
CCGGCCGCCT CGCTCAGCTC CCTGCACAGC GGCTCGTCGG GCTCCGAGCA GGACTTCGCC 
TATCTCAGCA GCTGGGGTCC GCGCTTCCGG CCCCTGGCCG CGCTCTACGC CGGCCACCGC 
GGGGACGACG AGGCCCAGGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH22 ( XM_024451967.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307735.1 Homo sapiens cadherin 22 (CDH22), transcript variant X3, mRNA.

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CloneID	OHu105153
Clone ID Related Accession (Same CDS sequence)	XM_024451967.1
Accession Version	XM_024451967.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cadherin-22 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGATGAGGA AACAGAGGCT 
CAGGGAAGAA CAGGGATGGC CCCAAGATCA CAGAGCAAGT CCTGGCAGGG GCAGGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307735.1
CDS	135..1634
Translation	MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADEETEAQGRTGMAPRSQSKSWQGQA

Target ORF information:

RefSeq Version	XM_024451967.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451967.1

ORF Insert Sequence:

ATGAGGCCGA GGCCCGAAGG TAGGGGGCTC CGGGCGGGAG TCGCGCTGTC CCCCGCGCTA 
CTGCTGCTGC TGCTGCTGCC GCCGCCGCCG ACGCTGCTGG GGCGCCTGTG GGCAGCGGGC 
ACACCCTCGC CGTCGGCGCC CGGAGCTCGG CAGGACGGCG CGCTGGGAGC CGGCCGCGTC 
AAACGCGGCT GGGTGTGGAA CCAGTTCTTC GTGGTAGAGG AGTACACGGG CACGGAGCCC 
CTGTATGTGG GCAAGATCCA CTCCGACTCA GACGAGGGTG ACGGGGCCAT CAAGTACACC 
ATCTCAGGCG AGGGTGCTGG GACCATCTTC CTGATCGACG AGCTGACAGG CGACATTCAT 
GCCATGGAGC GCCTGGACCG CGAGCAGAAA ACCTTCTACA CGCTGCGGGC CCAGGCTCGG 
GATCGCGCCA CCAACCGCCT ACTGGAGCCC GAGTCGGAGT TCATCATCAA GGTGCAGGAC 
ATCAATGACA GTGAGCCCCG CTTCCTGCAC GGCCCCTATA TTGGCAGCGT GGCCGAGCTC 
TCACCTACAG GCACGTCGGT GATGCAGGTG ATGGCCTCGG ATGCGGATGA CCCCACGTAC 
GGCAGCAGCG CTCGGCTGGT GTACAGCGTG CTGGACGGCG AGCACCACTT CACCGTGGAC 
CCCAAGACCG GCGTAATCCG GACGGCTGTG CCTGACCTTG ACCGCGAGAG CCAGGAGCGC 
TACGAGGTGG TGATCCAGGC CACAGACATG GCGGGTCAGC TGGGTGGCCT CTCGGGCTCC 
ACTACCGTCA CCATCGTAGT CACCGACGTC AATGACAACC CGCCCCGTTT CCCGCAGAAG 
ATGTACCAGT TCAGCATCCA GGAGTCAGCC CCCATTGGAA CGGCTGTGGG ACGTGTGAAG 
GCTGAGGACT CAGACGTGGG AGAGAACACA GACATGACTT ACCACCTTAA GGACGAGAGC 
AGCAGCGGCG GCGATGTGTT CAAGGTCACC ACAGACAGCG ACACTCAGGA GGCCATCATC 
GTAGTGCAGA AGCGCCTGGA CTTCGAATCC CAGCCCGTGC ACACCGTGAT CCTGGAGGCC 
CTCAACAAGT TCGTGGACCC CCGCTTCGCC GACCTGGGCA CGTTCCGCGA CCAGGCGATC 
GTGCGCGTGG CCGTGACCGA CGTGGACGAG CCCCCCGAGT TCCGGCCGCC CTCCGGCCTC 
CTGGAGGTGC AGGAGGACGC GCAGGTGGGC TCCCTGGTCG GCGTGGTGAC GGCGCGGGAC 
CCCGACGCCG CCAACCGGCC CGTCCGGTAC GCCATTGACC GCGAATCAGA TTTGGACCAG 
ATCTTCGATA TCGATGCGGA CACAGGCGCC ATCGTGACTG GCAAGGGGCT GGACCGCGAG 
ACGGCCGGCT GGCACAACAT CACAGTGCTG GCCATGGAGG CGGATGAGGA AACAGAGGCT 
CAGGGAAGAA CAGGGATGGC CCCAAGATCA CAGAGCAAGT CCTGGCAGGG GCAGGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH22 ( XM_011528995.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527297.1 Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.

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CloneID	OHu53088
Clone ID Related Accession (Same CDS sequence)	XM_011528995.1 , XM_024451966.1
Accession Version	XM_011528995.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cadherin-22 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGCC TGGACCGCGA GCAGAAAACC TTCTACACGC TGCGGGCCCA GGCTCGGGAT 
CGCGCCACCA ACCGCCTACT GGAGCCCGAG TCGGAGTTCA TCATCAAGGT GCAGGACATC 
AATGACAGTG AGCCCCGCTT CCTGCACGGC CCCTATATTG GCAGCGTGGC CGAGCTCTCA 
CCTACAGGCA CGTCGGTGAT GCAGGTGATG GCCTCGGATG CGGATGACCC CACGTACGGC 
AGCAGCGCTC GGCTGGTGTA CAGCGTGCTG GACGGCGAGC ACCACTTCAC CGTGGACCCC 
AAGACCGGCG TAATCCGGAC GGCTGTGCCT GACCTTGACC GCGAGAGCCA GGAGCGCTAC 
GAGGTGGTGA TCCAGGCCAC AGACATGGCG GGTCAGCTGG GTGGCCTCTC GGGCTCCACT 
ACCGTCACCA TCGTAGTCAC CGACGTCAAT GACAACCCGC CCCGTTTCCC GCAGAAGATG 
TACCAGTTCA GCATCCAGGA GTCAGCCCCC ATTGGAACGG CTGTGGGACG TGTGAAGGCT 
GAGGACTCAG ACGTGGGAGA GAACACAGAC ATGACTTACC ACCTTAAGGA CGAGAGCAGC 
AGCGGCGGCG ATGTGTTCAA GGTCACCACA GACAGCGACA CTCAGGAGGC CATCATCGTA 
GTGCAGAAGC GCCTGGACTT CGAATCCCAG CCCGTGCACA CCGTGATCCT GGAGGCCCTC 
AACAAGTTCG TGGACCCCCG CTTCGCCGAC CTGGGCACGT TCCGCGACCA GGCGATCGTG 
CGCGTGGCCG TGACCGACGT GGACGAGCCC CCCGAGTTCC GGCCGCCCTC CGGCCTCCTG 
GAGGTGCAGG AGGACGCGCA GGTGGGCTCC CTGGTCGGCG TGGTGACGGC GCGGGACCCC 
GACGCCGCCA ACCGGCCCGT CCGGTACGCC ATTGACCGCG AATCAGATTT GGACCAGATC 
TTCGATATCG ATGCGGACAC AGGCGCCATC GTGACTGGCA AGGGGCTGGA CCGCGAGACG 
GCCGGCTGGC ACAACATCAC AGTGCTGGCC ATGGAGGCGG ACAATCATGC ACAGCTATCC 
CGGGCATCCC TAAGGATCCG AATCCTGGAT GTGAACGACA ATCCCCCAGA ACTGGCCACA 
CCCTACGAGG CAGCTGTATG CGAGGATGCC AAGCCAGGCC AGCTCATCCA GACCATCAGC 
GTGGTGGACA GAGACGAGCC CCAAGGCGGG CACCGCTTCT ATTTCCGCCT GGTGCCTGAA 
GCTCCCAGCA ACCCTCATTT CTCTCTGCTT GACATCCAAG ACAACACCGC TGCAGTGCAC 
ACGCAGCACG TGGGCTTCAA CCGGCAGGAG CAGGACGTGT TCTTCCTGCC CATCCTGGTG 
GTAGACAGTG GGCCGCCCAC ACTGAGCAGC ACAGGCACGC TCACCATCCG CATCTGTGGC 
TGCGACAGCT CCGGCACCAT CCAGTCCTGC AACACCACGG CCTTTGTCAT GGCCGCCTCC 
CTCAGCCCCG GCGCCCTCAT CGCCCTCTTG GTCTGCGTTC TCATCCTGGT TGTGCTGGTG 
CTGCTGATCC TCACCCTCAG GCGCCACCAC AAGAGCCACC TGAGCTCGGA CGAGGATGAA 
GACATGCGGG ACAACGTCAT CAAATACAAC GACGAAGGCG GCGGCGAGCA GGACACCGAA 
GCCTACGACA TGTCGGCGCT GCGGAGCCTC TACGACTTCG GCGAGCTCAA GGGCGGCGAC 
GGGGGCGGCA GCGCGGGCGG GGGAGCGGGC GGGGGCTCGG GCGGGGGCGC GGGCAGCCCC 
CCGCAGGCCC ACCTGCCCTC CGAGCGCCAC TCGCTGCCGC AGGGGCCGCC GAGCCCCGAG 
CCAGACTTCT CAGTGTTCAG GGACTTCATC AGCCGCAAGG TGGCACTGGC GGACGGGGAC 
CTGTCGGTGC CGCCCTACGA CGCCTTCCAG ACCTACGCCT TCGAGGGCGC GGACTCGCCG 
GCCGCCTCGC TCAGCTCCCT GCACAGCGGC TCGTCGGGCT CCGAGCAGGA CTTCGCCTAT 
CTCAGCAGCT GGGGTCCGCG CTTCCGGCCC CTGGCCGCGC TCTACGCCGG CCACCGCGGG 
GACGACGAGG CCCAGGCCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527297.1
CDS	771..2894
Translation	MERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS

Target ORF information:

RefSeq Version	XM_011528995.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528995.1

ORF Insert Sequence:

ATGGAGCGCC TGGACCGCGA GCAGAAAACC TTCTACACGC TGCGGGCCCA GGCTCGGGAT 
CGCGCCACCA ACCGCCTACT GGAGCCCGAG TCGGAGTTCA TCATCAAGGT GCAGGACATC 
AATGACAGTG AGCCCCGCTT CCTGCACGGC CCCTATATTG GCAGCGTGGC CGAGCTCTCA 
CCTACAGGCA CGTCGGTGAT GCAGGTGATG GCCTCGGATG CGGATGACCC CACGTACGGC 
AGCAGCGCTC GGCTGGTGTA CAGCGTGCTG GACGGCGAGC ACCACTTCAC CGTGGACCCC 
AAGACCGGCG TAATCCGGAC GGCTGTGCCT GACCTTGACC GCGAGAGCCA GGAGCGCTAC 
GAGGTGGTGA TCCAGGCCAC AGACATGGCG GGTCAGCTGG GTGGCCTCTC GGGCTCCACT 
ACCGTCACCA TCGTAGTCAC CGACGTCAAT GACAACCCGC CCCGTTTCCC GCAGAAGATG 
TACCAGTTCA GCATCCAGGA GTCAGCCCCC ATTGGAACGG CTGTGGGACG TGTGAAGGCT 
GAGGACTCAG ACGTGGGAGA GAACACAGAC ATGACTTACC ACCTTAAGGA CGAGAGCAGC 
AGCGGCGGCG ATGTGTTCAA GGTCACCACA GACAGCGACA CTCAGGAGGC CATCATCGTA 
GTGCAGAAGC GCCTGGACTT CGAATCCCAG CCCGTGCACA CCGTGATCCT GGAGGCCCTC 
AACAAGTTCG TGGACCCCCG CTTCGCCGAC CTGGGCACGT TCCGCGACCA GGCGATCGTG 
CGCGTGGCCG TGACCGACGT GGACGAGCCC CCCGAGTTCC GGCCGCCCTC CGGCCTCCTG 
GAGGTGCAGG AGGACGCGCA GGTGGGCTCC CTGGTCGGCG TGGTGACGGC GCGGGACCCC 
GACGCCGCCA ACCGGCCCGT CCGGTACGCC ATTGACCGCG AATCAGATTT GGACCAGATC 
TTCGATATCG ATGCGGACAC AGGCGCCATC GTGACTGGCA AGGGGCTGGA CCGCGAGACG 
GCCGGCTGGC ACAACATCAC AGTGCTGGCC ATGGAGGCGG ACAATCATGC ACAGCTATCC 
CGGGCATCCC TAAGGATCCG AATCCTGGAT GTGAACGACA ATCCCCCAGA ACTGGCCACA 
CCCTACGAGG CAGCTGTATG CGAGGATGCC AAGCCAGGCC AGCTCATCCA GACCATCAGC 
GTGGTGGACA GAGACGAGCC CCAAGGCGGG CACCGCTTCT ATTTCCGCCT GGTGCCTGAA 
GCTCCCAGCA ACCCTCATTT CTCTCTGCTT GACATCCAAG ACAACACCGC TGCAGTGCAC 
ACGCAGCACG TGGGCTTCAA CCGGCAGGAG CAGGACGTGT TCTTCCTGCC CATCCTGGTG 
GTAGACAGTG GGCCGCCCAC ACTGAGCAGC ACAGGCACGC TCACCATCCG CATCTGTGGC 
TGCGACAGCT CCGGCACCAT CCAGTCCTGC AACACCACGG CCTTTGTCAT GGCCGCCTCC 
CTCAGCCCCG GCGCCCTCAT CGCCCTCTTG GTCTGCGTTC TCATCCTGGT TGTGCTGGTG 
CTGCTGATCC TCACCCTCAG GCGCCACCAC AAGAGCCACC TGAGCTCGGA CGAGGATGAA 
GACATGCGGG ACAACGTCAT CAAATACAAC GACGAAGGCG GCGGCGAGCA GGACACCGAA 
GCCTACGACA TGTCGGCGCT GCGGAGCCTC TACGACTTCG GCGAGCTCAA GGGCGGCGAC 
GGGGGCGGCA GCGCGGGCGG GGGAGCGGGC GGGGGCTCGG GCGGGGGCGC GGGCAGCCCC 
CCGCAGGCCC ACCTGCCCTC CGAGCGCCAC TCGCTGCCGC AGGGGCCGCC GAGCCCCGAG 
CCAGACTTCT CAGTGTTCAG GGACTTCATC AGCCGCAAGG TGGCACTGGC GGACGGGGAC 
CTGTCGGTGC CGCCCTACGA CGCCTTCCAG ACCTACGCCT TCGAGGGCGC GGACTCGCCG 
GCCGCCTCGC TCAGCTCCCT GCACAGCGGC TCGTCGGGCT CCGAGCAGGA CTTCGCCTAT 
CTCAGCAGCT GGGGTCCGCG CTTCCGGCCC CTGGCCGCGC TCTACGCCGG CCACCGCGGG 
GACGACGAGG CCCAGGCCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH22 ( XM_024451966.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307734.1 Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.

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CloneID	OHu53088
Clone ID Related Accession (Same CDS sequence)	XM_011528995.1 , XM_024451966.1
Accession Version	XM_024451966.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cadherin-22 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGCC TGGACCGCGA GCAGAAAACC TTCTACACGC TGCGGGCCCA GGCTCGGGAT 
CGCGCCACCA ACCGCCTACT GGAGCCCGAG TCGGAGTTCA TCATCAAGGT GCAGGACATC 
AATGACAGTG AGCCCCGCTT CCTGCACGGC CCCTATATTG GCAGCGTGGC CGAGCTCTCA 
CCTACAGGCA CGTCGGTGAT GCAGGTGATG GCCTCGGATG CGGATGACCC CACGTACGGC 
AGCAGCGCTC GGCTGGTGTA CAGCGTGCTG GACGGCGAGC ACCACTTCAC CGTGGACCCC 
AAGACCGGCG TAATCCGGAC GGCTGTGCCT GACCTTGACC GCGAGAGCCA GGAGCGCTAC 
GAGGTGGTGA TCCAGGCCAC AGACATGGCG GGTCAGCTGG GTGGCCTCTC GGGCTCCACT 
ACCGTCACCA TCGTAGTCAC CGACGTCAAT GACAACCCGC CCCGTTTCCC GCAGAAGATG 
TACCAGTTCA GCATCCAGGA GTCAGCCCCC ATTGGAACGG CTGTGGGACG TGTGAAGGCT 
GAGGACTCAG ACGTGGGAGA GAACACAGAC ATGACTTACC ACCTTAAGGA CGAGAGCAGC 
AGCGGCGGCG ATGTGTTCAA GGTCACCACA GACAGCGACA CTCAGGAGGC CATCATCGTA 
GTGCAGAAGC GCCTGGACTT CGAATCCCAG CCCGTGCACA CCGTGATCCT GGAGGCCCTC 
AACAAGTTCG TGGACCCCCG CTTCGCCGAC CTGGGCACGT TCCGCGACCA GGCGATCGTG 
CGCGTGGCCG TGACCGACGT GGACGAGCCC CCCGAGTTCC GGCCGCCCTC CGGCCTCCTG 
GAGGTGCAGG AGGACGCGCA GGTGGGCTCC CTGGTCGGCG TGGTGACGGC GCGGGACCCC 
GACGCCGCCA ACCGGCCCGT CCGGTACGCC ATTGACCGCG AATCAGATTT GGACCAGATC 
TTCGATATCG ATGCGGACAC AGGCGCCATC GTGACTGGCA AGGGGCTGGA CCGCGAGACG 
GCCGGCTGGC ACAACATCAC AGTGCTGGCC ATGGAGGCGG ACAATCATGC ACAGCTATCC 
CGGGCATCCC TAAGGATCCG AATCCTGGAT GTGAACGACA ATCCCCCAGA ACTGGCCACA 
CCCTACGAGG CAGCTGTATG CGAGGATGCC AAGCCAGGCC AGCTCATCCA GACCATCAGC 
GTGGTGGACA GAGACGAGCC CCAAGGCGGG CACCGCTTCT ATTTCCGCCT GGTGCCTGAA 
GCTCCCAGCA ACCCTCATTT CTCTCTGCTT GACATCCAAG ACAACACCGC TGCAGTGCAC 
ACGCAGCACG TGGGCTTCAA CCGGCAGGAG CAGGACGTGT TCTTCCTGCC CATCCTGGTG 
GTAGACAGTG GGCCGCCCAC ACTGAGCAGC ACAGGCACGC TCACCATCCG CATCTGTGGC 
TGCGACAGCT CCGGCACCAT CCAGTCCTGC AACACCACGG CCTTTGTCAT GGCCGCCTCC 
CTCAGCCCCG GCGCCCTCAT CGCCCTCTTG GTCTGCGTTC TCATCCTGGT TGTGCTGGTG 
CTGCTGATCC TCACCCTCAG GCGCCACCAC AAGAGCCACC TGAGCTCGGA CGAGGATGAA 
GACATGCGGG ACAACGTCAT CAAATACAAC GACGAAGGCG GCGGCGAGCA GGACACCGAA 
GCCTACGACA TGTCGGCGCT GCGGAGCCTC TACGACTTCG GCGAGCTCAA GGGCGGCGAC 
GGGGGCGGCA GCGCGGGCGG GGGAGCGGGC GGGGGCTCGG GCGGGGGCGC GGGCAGCCCC 
CCGCAGGCCC ACCTGCCCTC CGAGCGCCAC TCGCTGCCGC AGGGGCCGCC GAGCCCCGAG 
CCAGACTTCT CAGTGTTCAG GGACTTCATC AGCCGCAAGG TGGCACTGGC GGACGGGGAC 
CTGTCGGTGC CGCCCTACGA CGCCTTCCAG ACCTACGCCT TCGAGGGCGC GGACTCGCCG 
GCCGCCTCGC TCAGCTCCCT GCACAGCGGC TCGTCGGGCT CCGAGCAGGA CTTCGCCTAT 
CTCAGCAGCT GGGGTCCGCG CTTCCGGCCC CTGGCCGCGC TCTACGCCGG CCACCGCGGG 
GACGACGAGG CCCAGGCCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307734.1
CDS	243..2366
Translation	MERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS

Target ORF information:

RefSeq Version	XM_024451966.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 22 (CDH22), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451966.1

ORF Insert Sequence:

ATGGAGCGCC TGGACCGCGA GCAGAAAACC TTCTACACGC TGCGGGCCCA GGCTCGGGAT 
CGCGCCACCA ACCGCCTACT GGAGCCCGAG TCGGAGTTCA TCATCAAGGT GCAGGACATC 
AATGACAGTG AGCCCCGCTT CCTGCACGGC CCCTATATTG GCAGCGTGGC CGAGCTCTCA 
CCTACAGGCA CGTCGGTGAT GCAGGTGATG GCCTCGGATG CGGATGACCC CACGTACGGC 
AGCAGCGCTC GGCTGGTGTA CAGCGTGCTG GACGGCGAGC ACCACTTCAC CGTGGACCCC 
AAGACCGGCG TAATCCGGAC GGCTGTGCCT GACCTTGACC GCGAGAGCCA GGAGCGCTAC 
GAGGTGGTGA TCCAGGCCAC AGACATGGCG GGTCAGCTGG GTGGCCTCTC GGGCTCCACT 
ACCGTCACCA TCGTAGTCAC CGACGTCAAT GACAACCCGC CCCGTTTCCC GCAGAAGATG 
TACCAGTTCA GCATCCAGGA GTCAGCCCCC ATTGGAACGG CTGTGGGACG TGTGAAGGCT 
GAGGACTCAG ACGTGGGAGA GAACACAGAC ATGACTTACC ACCTTAAGGA CGAGAGCAGC 
AGCGGCGGCG ATGTGTTCAA GGTCACCACA GACAGCGACA CTCAGGAGGC CATCATCGTA 
GTGCAGAAGC GCCTGGACTT CGAATCCCAG CCCGTGCACA CCGTGATCCT GGAGGCCCTC 
AACAAGTTCG TGGACCCCCG CTTCGCCGAC CTGGGCACGT TCCGCGACCA GGCGATCGTG 
CGCGTGGCCG TGACCGACGT GGACGAGCCC CCCGAGTTCC GGCCGCCCTC CGGCCTCCTG 
GAGGTGCAGG AGGACGCGCA GGTGGGCTCC CTGGTCGGCG TGGTGACGGC GCGGGACCCC 
GACGCCGCCA ACCGGCCCGT CCGGTACGCC ATTGACCGCG AATCAGATTT GGACCAGATC 
TTCGATATCG ATGCGGACAC AGGCGCCATC GTGACTGGCA AGGGGCTGGA CCGCGAGACG 
GCCGGCTGGC ACAACATCAC AGTGCTGGCC ATGGAGGCGG ACAATCATGC ACAGCTATCC 
CGGGCATCCC TAAGGATCCG AATCCTGGAT GTGAACGACA ATCCCCCAGA ACTGGCCACA 
CCCTACGAGG CAGCTGTATG CGAGGATGCC AAGCCAGGCC AGCTCATCCA GACCATCAGC 
GTGGTGGACA GAGACGAGCC CCAAGGCGGG CACCGCTTCT ATTTCCGCCT GGTGCCTGAA 
GCTCCCAGCA ACCCTCATTT CTCTCTGCTT GACATCCAAG ACAACACCGC TGCAGTGCAC 
ACGCAGCACG TGGGCTTCAA CCGGCAGGAG CAGGACGTGT TCTTCCTGCC CATCCTGGTG 
GTAGACAGTG GGCCGCCCAC ACTGAGCAGC ACAGGCACGC TCACCATCCG CATCTGTGGC 
TGCGACAGCT CCGGCACCAT CCAGTCCTGC AACACCACGG CCTTTGTCAT GGCCGCCTCC 
CTCAGCCCCG GCGCCCTCAT CGCCCTCTTG GTCTGCGTTC TCATCCTGGT TGTGCTGGTG 
CTGCTGATCC TCACCCTCAG GCGCCACCAC AAGAGCCACC TGAGCTCGGA CGAGGATGAA 
GACATGCGGG ACAACGTCAT CAAATACAAC GACGAAGGCG GCGGCGAGCA GGACACCGAA 
GCCTACGACA TGTCGGCGCT GCGGAGCCTC TACGACTTCG GCGAGCTCAA GGGCGGCGAC 
GGGGGCGGCA GCGCGGGCGG GGGAGCGGGC GGGGGCTCGG GCGGGGGCGC GGGCAGCCCC 
CCGCAGGCCC ACCTGCCCTC CGAGCGCCAC TCGCTGCCGC AGGGGCCGCC GAGCCCCGAG 
CCAGACTTCT CAGTGTTCAG GGACTTCATC AGCCGCAAGG TGGCACTGGC GGACGGGGAC 
CTGTCGGTGC CGCCCTACGA CGCCTTCCAG ACCTACGCCT TCGAGGGCGC GGACTCGCCG 
GCCGCCTCGC TCAGCTCCCT GCACAGCGGC TCGTCGGGCT CCGAGCAGGA CTTCGCCTAT 
CTCAGCAGCT GGGGTCCGCG CTTCCGGCCC CTGGCCGCGC TCTACGCCGG CCACCGCGGG 
GACGACGAGG CCCAGGCCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.
Oncogene(2017 Oct)
Kelly NJ,Varga JFA,Specker EJ,Romeo CM,Coomber BL,Uniacke J

Clinical epigenetics97(2017)
Mart?n-S?nchez E,Mendaza S,Ulazia-Garmendia A,Monreal-Santesteban I,C?rdoba A,Vicente-Garc?a F,Blanco-Luquin I,De La Cruz S,Aramendia A,Guerrero-Setas D

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
PLoS genetics9(1)e1003225(2013)
Lauc G,Huffman JE,Pu?i? M,Zgaga L,Adamczyk B,Mu?ini? A,Novokmet M,Pola?ek O,Gornik O,Kri?ti? J,Keser T,Vitart V,Scheijen B,Uh HW,Molokhia M,Patrick AL,McKeigue P,Kol?i? I,Luki? IK,Swann O,van Leeuwen FN,Ruhaak LR,Houwing-Duistermaat JJ,Slagboom PE,Beekman M,de Craen AJ,Deelder AM,Zeng Q,Wang W,Hastie ND,Gyllensten U,Wilson JF,Wuhrer M,Wright AF,Rudd PM,Hayward C,Aulchenko Y,Campbell H,Rudan I

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
Genomics96(4)211-9(2010 Oct)
Lewis JP,Palmer ND,Ellington JB,Divers J,Ng MC,Lu L,Langefeld CD,Freedman BI,Bowden DW

Over-expression of CDH22 is associated with tumor progression in colorectal cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine30(3)130-40(2009)
Zhou J,Li J,Chen J,Liu Y,Gao W,Ding Y

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CDH22 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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