NFKBIZ cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFKBIZ
Entrez Gene ID	64332
Full Name	NFKB inhibitor zeta
Synonyms	IKBZ,INAP,MAIL
General protein information	Preferred Names NFKB inhibitor zeta Names NF-kappa-B inhibitor zeta I-kappa-B-zeta IL-1 inducible nuclear ankyrin-repeat protein Ikappa B-zeta variant 3 IkappaB-zeta ikB-zeta ikappaBzeta molecule possessing ankyrin repeats induced by lipopolysaccharide nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q12.3
Summary	This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	608004

mRNA and Protein(s)

mRNA	Protein	Name
NM_031419.3	NP_113607.1	NF-kappa-B inhibitor zeta isoform a
NM_001005474.2	NP_001005474.1	NF-kappa-B inhibitor zeta isoform b
NM_001005474.3	NP_001005474.1	NF-kappa-B inhibitor zeta isoform b
NM_031419.4	NP_113607.1	NF-kappa-B inhibitor zeta isoform a

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NFKBIZ	XP_005639490.1
Gallus gallus (chicken)	NFKBIZ	NP_001006254.1
Xenopus tropicalis (tropical clawed frog)	LOC100485153	XP_002932322.1
Pan troglodytes (chimpanzee)	NFKBIZ	XP_516633.3
Mus musculus (house mouse)	Nfkbiz	NP_001152866.1
Bos taurus (cattle)	NFKBIZ	NP_777151.1
Rattus norvegicus (Norway rat)	Nfkbiz	NP_001100565.1
Xenopus tropicalis (tropical clawed frog)	nfkbiz	NP_001123738.1
Homo sapiens (human)	NFKBIZ	NP_113607.1
	NFKBIZ	XP_001099425.1

Gene Ontology
Bibliography

Related articles in PubMed

NFKBIZ in Psoriasis: Assessing the association with gene polymorphisms and report of a new transcript variant.
Coto-Segura P, Gonzalez-Lara L, G?mez J, Eiris N, Batalla A, G?mez C, Requena S, Queiro R, Alonso B, Iglesias S, Coto E
Human immunology78(5-6)435-440(2017 May - Jun)

Sodium azide suppresses LPS-induced expression MCP-1 through regulating I?B? and STAT1 activities in macrophages.
Park CY, Heo JN, Suk K, Lee WH
Cellular immunology31564-70(2017 May)

I?B? Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.
Sundaram K, Rahman MA, Mitra S, Knoell DL, Woodiga SA, King SJ, Wewers MD
PloS one11(9)e0161931(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In cultured macrophages, LPS-induced expression of monocyte chemoattractant protein (MCP)-1 was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta activities.
Title: Sodium azide suppresses LPS-induced expression MCP-1 through regulating I?B? and STAT1 activities in macrophages.

a specific IL-17A-induced gene, NFKBIZ, which encodes IkappaB-zeta, a transcriptional regulator for NF-kappaB, was demonstrated to have a significant role for IL-17A-induced gene expression.
Title: IL-17A plays a central role in the expression of psoriasis signature genes through the induction of I?B-? in keratinocytes.

TNF-alpha- and IL-17A mediate synergistic induction of DEFB4 gene expression in human keratinocytes through IkappaBzeta
Title: Characterization of TNF-?- and IL-17A-Mediated Synergistic Induction of?DEFB4 Gene Expression in Human Keratinocytes through I?B?.

IkappaB-zeta regulates human monocyte pro-inflammatory responses induced by Streptococcus pneumoniae.
Title: I?B? Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.

These results indicate that the LPS/IL-1beta-MyD88 axis plays a crucial role for stabilization of IkappaB-zeta mRNA.
Title: Screening of posttranscriptional regulatory molecules of I?B-?.

The following NFKBIZ gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFKBIZ cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14974	NM_031419.4 Latest version!	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu15086	NM_001005474.3 Latest version!	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu15086	NM_001005474.2	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu14974	NM_031419.3	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFKBIZ ( NM_031419.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_113607.1 Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14974
Clone ID Related Accession (Same CDS sequence)	NM_031419.3 , NM_031419.4
Accession Version	NM_031419.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor zeta isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC060800.1, BC014587.2 and AW004900.1. On Jul 1, 2010 this sequence version replaced NM_031419.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060800.1, AB037925.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATTGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCG GGACGCGGCG 
GGCGGCTGCG GCCTCATGAC CAGCCCGCTC AACCTGAGCT ACTTCTACGG CGCGTCGCCG 
CCCGCCGCCG CCCCGGGCGC CTGCGACGCC AGCTGCTCGG TCTTGGGCCC CTCGGCGCCC 
GGCTCGCCCG GCTCCGACTC CTCCGACTTC TCCTCTGCCT CGTCGGTGTC CTCCTGCGGC 
GCCGTGGAGT CCCGGTCGAG AGGCGGCGCC CGCGCCGAGC GCCAGCCAGT TGAGCCCCAT 
ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113607.1
CDS	116..2272
Translation	MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAPGSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY

Target ORF information:

RefSeq Version	NM_031419.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031419.3

ORF Insert Sequence:

ATGATTGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCG GGACGCGGCG 
GGCGGCTGCG GCCTCATGAC CAGCCCGCTC AACCTGAGCT ACTTCTACGG CGCGTCGCCG 
CCCGCCGCCG CCCCGGGCGC CTGCGACGCC AGCTGCTCGG TCTTGGGCCC CTCGGCGCCC 
GGCTCGCCCG GCTCCGACTC CTCCGACTTC TCCTCTGCCT CGTCGGTGTC CTCCTGCGGC 
GCCGTGGAGT CCCGGTCGAG AGGCGGCGCC CGCGCCGAGC GCCAGCCAGT TGAGCCCCAT 
ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIZ ( NM_031419.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_113607.1 Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14974
Clone ID Related Accession (Same CDS sequence)	NM_031419.3 , NM_031419.4
Accession Version	NM_031419.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor zeta isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC060800.1 and BC014587.2. On Nov 23, 2018 this sequence version replaced NM_031419.3. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060800.1, SRR1660809.227881.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000326172.9/ ENSP00000325663.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATTGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCG GGACGCGGCG 
GGCGGCTGCG GCCTCATGAC CAGCCCGCTC AACCTGAGCT ACTTCTACGG CGCGTCGCCG 
CCCGCCGCCG CCCCGGGCGC CTGCGACGCC AGCTGCTCGG TCTTGGGCCC CTCGGCGCCC 
GGCTCGCCCG GCTCCGACTC CTCCGACTTC TCCTCTGCCT CGTCGGTGTC CTCCTGCGGC 
GCCGTGGAGT CCCGGTCGAG AGGCGGCGCC CGCGCCGAGC GCCAGCCAGT TGAGCCCCAT 
ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113607.1
CDS	116..2272
Translation	MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAPGSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY

Target ORF information:

RefSeq Version	NM_031419.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031419.4

ORF Insert Sequence:

ATGATTGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCG GGACGCGGCG 
GGCGGCTGCG GCCTCATGAC CAGCCCGCTC AACCTGAGCT ACTTCTACGG CGCGTCGCCG 
CCCGCCGCCG CCCCGGGCGC CTGCGACGCC AGCTGCTCGG TCTTGGGCCC CTCGGCGCCC 
GGCTCGCCCG GCTCCGACTC CTCCGACTTC TCCTCTGCCT CGTCGGTGTC CTCCTGCGGC 
GCCGTGGAGT CCCGGTCGAG AGGCGGCGCC CGCGCCGAGC GCCAGCCAGT TGAGCCCCAT 
ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIZ ( NM_001005474.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005474.1 Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.

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CloneID	OHu15086
Clone ID Related Accession (Same CDS sequence)	NM_001005474.2 , NM_001005474.3
Accession Version	NM_001005474.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-01
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor zeta isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA541852.1, AF548362.1, BC014587.2, BX492097.1 and AW004900.1. On Jul 1, 2010 this sequence version replaced NM_001005474.1. Transcript Variant: This variant (2) contains alternative 5' non-coding exons compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in a shorter isoform (b) compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF548362.1, AK054787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005474.1
CDS	283..2139
Translation	MGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY

Target ORF information:

RefSeq Version	NM_001005474.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005474.2

ORF Insert Sequence:

ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIZ ( NM_001005474.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005474.1 Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15086
Clone ID Related Accession (Same CDS sequence)	NM_001005474.2 , NM_001005474.3
Accession Version	NM_001005474.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor zeta isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA541852.1, AF548362.1, BC014587.2, BX492097.1 and AW004900.1. On May 31, 2019 this sequence version replaced NM_001005474.2. Transcript Variant: This variant (2) contains alternative 5' non-coding exons compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in a shorter isoform (b) compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF548362.1, AK054787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005474.1
CDS	283..2139
Translation	MGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY

Target ORF information:

RefSeq Version	NM_001005474.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor zeta (NFKBIZ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005474.3

ORF Insert Sequence:

ATGGGGGTTG GCAGGCAGCA GAGAGGCCCC TTTCAAGGTG TTCGGGTAAA GAACTCAGTG 
AAGGAACTCC TGTTGCACAT CCGAAGTCAT AAACAGAAGG CTTCTGGCCA AGCTGTGGAT 
GATTTTAAGA CACAAGGTGT GAACATAGAA CAGTTCAGAG AATTGAAGAA CACAGTATCA 
TACAGTGGGA AAAGGAAAGG GCCCGATTCG TTGTCTGATG GACCTGCTTG CAAAAGGCCA 
GCTCTGTTGC ATTCCCAATT TTTGACACCA CCTCAAACAC CAACGCCCGG GGAGAGCATG 
GAAGATGTTC ATCTCAATGA ACCCAAACAG GAGAGCAGTG CTGATCTGCT TCAGAACATT 
ATCAACATTA AGAATGAATG CAGCCCCGTT TCCCTGAACA CAGTTCAAGT TAGCTGGCTG 
AACCCCGTGG TGGTCCCTCA GAGCTCCCCC GCAGAGCAGT GTCAGGACTT CCATGGAGGG 
CAGGTCTTTT CTCCACCTCA GAAATGCCAA CCATTCCAAG TCAGGGGCTC CCAACAAATG 
ATAGACCAGG CTTCCCTGTA CCAGTATTCT CCACAGAACC AGCATGTAGA GCAGCAGCCA 
CACTACACCC ACAAACCAAC TCTGGAATAC AGTCCTTTTC CCATACCTCC CCAGTCCCCC 
GCTTATGAAC CAAACCTCTT TGATGGTCCA GAATCACAGT TTTGCCCAAA CCAAAGCTTA 
GTTTCCCTTC TTGGTGATCA AAGGGAATCT GAGAATATTG CTAATCCCAT GCAGACTTCC 
TCCAGTGTTC AGCAGCAAAA TGATGCTCAC TTGCACAGCT TCAGCATGAT GCCCAGCAGC 
GCCTGTGAGG CCATGGTGGG GCACGAGATG GCCTCTGACT CTTCAAACAC TTCACTGCCA 
TTCTCAAACA TGGGAAATCC AATGAACACC ACACAGTTAG GGAAATCACT TTTTCAGTGG 
CAGGTGGAGC AGGAAGAAAG CAAATTGGCA AATATTTCCC AAGACCAGTT TCTTTCAAAG 
GATGCAGATG GTGACACGTT CCTTCATATT GCTGTTGCCC AAGGGAGAAG GGCACTTTCC 
TATGTTCTTG CAAGAAAGAT GAATGCACTT CACATGCTGG ATATTAAAGA GCACAATGGA 
CAGAGTGCCT TTCAGGTGGC AGTGGCTGCC AATCAGCATC TCATTGTGCA GGATCTGGTG 
AACATCGGGG CACAGGTGAA CACCACAGAC TGCTGGGGAA GAACACCTCT GCATGTGTGT 
GCTGAGAAGG GCCACTCCCA GGTGCTTCAG GCGATTCAGA AGGGAGCAGT GGGAAGTAAT 
CAGTTTGTGG ATCTTGAGGC AACTAACTAT GATGGCCTGA CTCCCCTTCA CTGTGCAGTC 
ATAGCCCACA ATGCTGTGGT CCATGAACTC CAGAGAAATC AACAGCCTCA TTCACCTGAA 
GTTCAGGAGC TTTTACTGAA GAATAAGAGT CTGGTTGATA CCATTAAGTG CCTAATTCAA 
ATGGGAGCAG CGGTGGAAGC GAAGGATCGC AAAAGTGGCC GCACAGCCCT GCATTTGGCA 
GCTGAAGAAG CAAATCTGGA ACTCATTCGC CTCTTTTTGG AGCTGCCCAG TTGCCTGTCT 
TTTGTGAATG CAAAGGCTTA CAATGGCAAC ACTGCCCTCC ATGTTGCTGC CAGCTTGCAG 
TATCGGTTGA CACAATTAGA TGCTGTCCGC CTGTTGATGA GGAAGGGAGC AGACCCAAGT 
ACTCGGAACT TGGAGAACGA ACAGCCAGTG CATTTGGTTC CCGATGGCCC TGTGGGAGAA 
CAGATCCGAC GTATCCTGAA GGGAAAGTCC ATTCAGCAGA GAGCTCCACC GTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NFKBIZ in Psoriasis: Assessing the association with gene polymorphisms and report of a new transcript variant.
Human immunology78(5-6)435-440(2017 May - Jun)
Coto-Segura P,Gonzalez-Lara L,G?mez J,Eiris N,Batalla A,G?mez C,Requena S,Queiro R,Alonso B,Iglesias S,Coto E

Sodium azide suppresses LPS-induced expression MCP-1 through regulating I?B? and STAT1 activities in macrophages.
Cellular immunology31564-70(2017 May)
Park CY,Heo JN,Suk K,Lee WH

I?B? Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.
PloS one11(9)e0161931(2016)
Sundaram K,Rahman MA,Mitra S,Knoell DL,Woodiga SA,King SJ,Wewers MD

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NFKBIZ cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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FAX

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