ADPRM cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADPRM
Entrez Gene ID	56985
Full Name	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
Synonyms	C17orf48,MDS006,NBLA03831
General protein information	Preferred Names ADP-ribose/CDP-alcohol diphosphatase, manganese dependent Names manganese-dependent ADP-ribose/CDP-alcohol diphosphatase ADP-ribose/CDP-alcohol pyrophosphatase ADPRibase-Mn CDP-choline phosphohydrolase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_005256738.2	XP_005256795.1	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1
NM_020233.4	NP_064618.3	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
NM_020233.5	NP_064618.3	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ADPRM	XP_001164855.1
Bos taurus (cattle)	ADPRM	NP_001096749.2
Rattus norvegicus (Norway rat)	Adprm	NP_001009246.1
Danio rerio (zebrafish)	adprm	NP_956715.1
Canis lupus familiaris (dog)	ADPRM	XP_005620111.1
Mus musculus (house mouse)	Adprm	NP_079786.2
Arabidopsis thaliana (thale cress)	AT4G24730	NP_001119045.1
Homo sapiens (human)	ADPRM	NP_064618.3
Oryza sativa (rice)	Os07g0688000	NP_001060698.1
Oryza sativa (rice)	Os08g0557200	NP_001062482.1
	ADPRM	XP_001114048.1
Gallus gallus (chicken)	C17ORF48	XP_001231601.3
Xenopus tropicalis (tropical clawed frog)	adprm	NP_001008013.1

Gene Ontology
Bibliography

Related articles in PubMed

Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.
Cabezas A, Ribeiro JM, Rodrigues JR, L?pez-Villamizar I, Fern?ndez A, Canales J, Pinto RM, Costas MJ, Cameselle JC
PloS one10(2)e0118680(2015)

Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells.
Canales J, Fern?ndez A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ
The Biochemical journal413(1)103-13(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results from homology modeling and simulation studies of docking and molecular dynamics revealed the structural and dynamic information on human ADPRibase-Mn with the catalytic sites.
Title: Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.

The following ADPRM gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADPRM cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03256	NM_020233.5 Latest version!	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu49906	XM_005256738.2 Latest version!	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu03256	NM_020233.4	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADPRM ( NM_020233.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_064618.3 Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.

Price & Availability↑

CloneID	OHu03256
Clone ID Related Accession (Same CDS sequence)	NM_020233.4 , NM_020233.5
Accession Version	NM_020233.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA305828.1, AB073393.1 and DA280275.1. On Apr 27, 2006 this sequence version replaced NM_020233.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.79953.1, SRR1803614.170385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGTGAGC 
CATCTTCCCA TTTACCCGGA CGCCTCTGAC AATGTGTGCC TGGCCTGGAA CTACAGAGAT 
GCCCTGGCAG TCATTTGGTC TCATGAGTGT GTGGTGTGTT TCTTTGCTGG TCACACCCAT 
GATGGTGGCT ACTCTGAGGA TCCTTTTGGT GTATACCACG TCAACCTAGA AGGAGTTATT 
GAAACAGCTC CAGACAGCCA AGCCTTTGGC ACAGTTCATG TCTATCCTGA CAAAATGATG 
TTGAAAGGGA GAGGCAGAGT TCCAGATAGA ATTATGAATT ACAAGAAAGA AAGAGCCTTC 
CATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064618.3
CDS	76..1104
Translation	MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWNNESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREYLTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKYEQCMKILREHNPNTELNSPQGLSEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPIYPDASDNVCLAWNYRDALAVIWSHECVVCFFAGHTHDGGYSEDPFGVYHVNLEGVIETAPDSQAFGTVHVYPDKMMLKGRGRVPDRIMNYKKERAFHC

Target ORF information:

RefSeq Version	NM_020233.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020233.4

ORF Insert Sequence:

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGTGAGC 
CATCTTCCCA TTTACCCGGA CGCCTCTGAC AATGTGTGCC TGGCCTGGAA CTACAGAGAT 
GCCCTGGCAG TCATTTGGTC TCATGAGTGT GTGGTGTGTT TCTTTGCTGG TCACACCCAT 
GATGGTGGCT ACTCTGAGGA TCCTTTTGGT GTATACCACG TCAACCTAGA AGGAGTTATT 
GAAACAGCTC CAGACAGCCA AGCCTTTGGC ACAGTTCATG TCTATCCTGA CAAAATGATG 
TTGAAAGGGA GAGGCAGAGT TCCAGATAGA ATTATGAATT ACAAGAAAGA AAGAGCCTTC 
CATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADPRM ( NM_020233.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_064618.3 Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.

Price & Availability↑

CloneID	OHu03256
Clone ID Related Accession (Same CDS sequence)	NM_020233.4 , NM_020233.5
Accession Version	NM_020233.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC002347.3, DA305828.1, AB073393.1 and DA280275.1. On May 17, 2019 this sequence version replaced NM_020233.4. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.79953.1, SRR1803614.170385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379774.5/ ENSP00000369099.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGTGAGC 
CATCTTCCCA TTTACCCGGA CGCCTCTGAC AATGTGTGCC TGGCCTGGAA CTACAGAGAT 
GCCCTGGCAG TCATTTGGTC TCATGAGTGT GTGGTGTGTT TCTTTGCTGG TCACACCCAT 
GATGGTGGCT ACTCTGAGGA TCCTTTTGGT GTATACCACG TCAACCTAGA AGGAGTTATT 
GAAACAGCTC CAGACAGCCA AGCCTTTGGC ACAGTTCATG TCTATCCTGA CAAAATGATG 
TTGAAAGGGA GAGGCAGAGT TCCAGATAGA ATTATGAATT ACAAGAAAGA AAGAGCCTTC 
CATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064618.3
CDS	92..1120
Translation	MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWNNESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREYLTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKYEQCMKILREHNPNTELNSPQGLSEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPIYPDASDNVCLAWNYRDALAVIWSHECVVCFFAGHTHDGGYSEDPFGVYHVNLEGVIETAPDSQAFGTVHVYPDKMMLKGRGRVPDRIMNYKKERAFHC

Target ORF information:

RefSeq Version	NM_020233.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020233.5

ORF Insert Sequence:

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGTGAGC 
CATCTTCCCA TTTACCCGGA CGCCTCTGAC AATGTGTGCC TGGCCTGGAA CTACAGAGAT 
GCCCTGGCAG TCATTTGGTC TCATGAGTGT GTGGTGTGTT TCTTTGCTGG TCACACCCAT 
GATGGTGGCT ACTCTGAGGA TCCTTTTGGT GTATACCACG TCAACCTAGA AGGAGTTATT 
GAAACAGCTC CAGACAGCCA AGCCTTTGGC ACAGTTCATG TCTATCCTGA CAAAATGATG 
TTGAAAGGGA GAGGCAGAGT TCCAGATAGA ATTATGAATT ACAAGAAAGA AAGAGCCTTC 
CATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADPRM ( XM_005256738.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256795.1 Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49906
Clone ID Related Accession (Same CDS sequence)	XM_005256738.2
Accession Version	XM_005256738.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 885bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005256738.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGCCATC 
TTCCCATTTA CCCGGACGCC TCTGACAATG TGTGCCTGGC CTGGAACTAC AGAGATGCCC 
TGGCAGTCAT TTGGTCTCAT GAGTGTGTGG TGTGTTTCTT TGCTGGTCAC ACCCATGATG 
GTGGCTACTC TGAGGATCCT TTTGGTGTAT ACCACGTCAA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256795.1
CDS	76..960
Translation	MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWNNESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREYLTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKYEQCMKILREHNPNTELNSPQGLSEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIAIFPFTRTPLTMCAWPGTTEMPWQSFGLMSVWCVSLLVTPMMVATLRILLVYTTST

Target ORF information:

RefSeq Version	XM_005256738.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (ADPRM), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256738.2

ORF Insert Sequence:

ATGGATGATA AACCCAATCC TGAAGCCCTA AGTGACAGTT CAGAGCGTCT TTTCTCCTTT 
GGCGTCATCG CAGATGTTCA ATTTGCAGAC TTAGAAGATG GCTTTAATTT CCAAGGAACC 
AGGCGGCGAT ACTACAGACA TAGTCTTCTT CACTTACAGG GTGCCATTGA AGACTGGAAT 
AATGAAAGCA GCATGCCCTG TTGTGTCCTT CAGCTTGGAG ATATCATCGA TGGATATAAT 
GCACAGTATA ATGCATCCAA AAAGTCCCTA GAACTTGTTA TGGACATGTT CAAGAGGCTT 
AAAGTTCCAG TTCATCATAC ATGGGGAAAC CATGAATTCT ATAACTTCAG TAGAGAGTAT 
TTAACACACT CTAAACTTAA CACTAAGTTT CTAGAAGATC AGATTGTACA TCATCCTGAG 
ACCATGCCTT CAGAAGATTA TTATGCTTAT CATTTTGTAC CATTCCCTAA ATTCCGGTTC 
ATTTTACTTG ATGCATATGA CTTGAGTGTC TTGGGCGTGG ATCAGTCTTC TCCAAAATAC 
GAGCAGTGTA TGAAGATATT GAGGGAGCAC AATCCAAATA CGGAACTGAA TAGTCCTCAA 
GGACTTTCTG AGCCCCAGTT TGTCCAGTTT AATGGAGGAT TCAGCCAAGA ACAGCTAAAC 
TGGTTGAATG AAGTGCTAAC ATTCTCTGAC ACAAACCAAG AAAAGGTGGT GATTGCCATC 
TTCCCATTTA CCCGGACGCC TCTGACAATG TGTGCCTGGC CTGGAACTAC AGAGATGCCC 
TGGCAGTCAT TTGGTCTCAT GAGTGTGTGG TGTGTTTCTT TGCTGGTCAC ACCCATGATG 
GTGGCTACTC TGAGGATCCT TTTGGTGTAT ACCACGTCAA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.
PloS one10(2)e0118680(2015)
Cabezas A,Ribeiro JM,Rodrigues JR,L?pez-Villamizar I,Fern?ndez A,Canales J,Pinto RM,Costas MJ,Cameselle JC

Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells.
The Biochemical journal413(1)103-13(2008 Jul)
Canales J,Fern?ndez A,Ribeiro JM,Cabezas A,Rodrigues JR,Cameselle JC,Costas MJ