KYAT3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KYAT3
Entrez Gene ID	56267
Full Name	kynurenine aminotransferase 3
Synonyms	CCBL2,KAT3,KATIII
General protein information	Preferred Names kynurenine aminotransferase 3 Names kynurenine--oxoglutarate transaminase 3 cysteine-S-conjugate beta-lyase 2 kynurenine aminotransferase III kynurenine--glyoxylate transaminase kynurenine--oxoglutarate transaminase III
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.2
Summary	This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid, which is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Mar 2017].
Disorder MIM:	610656

mRNA and Protein(s)

mRNA	Protein	Name
NM_001349449.1	NP_001336378.1	kynurenine--oxoglutarate transaminase 3 isoform 3
NM_001349450.1	NP_001336379.1	kynurenine--oxoglutarate transaminase 3 isoform 3
NM_001008662.2	NP_001008662.1	kynurenine--oxoglutarate transaminase 3 isoform 2
NM_001349448.1	NP_001336377.1	kynurenine--oxoglutarate transaminase 3 isoform 1
NM_001008661.3	NP_001008661.1	kynurenine--oxoglutarate transaminase 3 isoform 1
NM_001349447.1	NP_001336376.1	kynurenine--oxoglutarate transaminase 3 isoform 2
NM_001008661.2	NP_001008661.1	kynurenine--oxoglutarate transaminase 3 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCBL2	NP_001008661.1
Oryza sativa (rice)	Os09g0453800	NP_001063347.1
	CCBL2	XP_001082463.2
Canis lupus familiaris (dog)	CCBL2	XP_005622013.1
Caenorhabditis elegans (roundworm)	nkat-1	NP_510355.1
Kluyveromyces lactis	KLLA0F01617g	XP_455153.1
Schizosaccharomyces pombe (fission yeast)	SPAC6B12.04c	NP_593759.1
Danio rerio (zebrafish)	LOC100332215	XP_002662473.1
Danio rerio (zebrafish)	ccbl2	NP_956638.1
Caenorhabditis elegans (roundworm)	nkat-3	NP_001024822.1
Magnaporthe oryzae (rice blast fungus)	MGG_03264	XP_003716706.1
Neurospora crassa	NCU03347	XP_956456.1
Pan troglodytes (chimpanzee)	CCBL2	XP_001146041.1
Bos taurus (cattle)	CCBL2	NP_001068838.1
Mus musculus (house mouse)	Ccbl2	NP_776124.1
Rattus norvegicus (Norway rat)	Kat3	NP_001015037.1
Gallus gallus (chicken)	CCBL2	XP_004936687.1
Danio rerio (zebrafish)	si:ch73-97h19.2	XP_699860.2
Danio rerio (zebrafish)	LOC567074	XP_695456.3
Drosophila melanogaster (fruit fly)	CG6950	NP_788640.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011158	XP_309491.4
Saccharomyces cerevisiae (baker's yeast)	BNA3	NP_012475.3
Arabidopsis thaliana (thale cress)	AT1G77670	NP_177890.1

Gene Ontology
Bibliography

Related articles in PubMed

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.
Matysik-Wo?niak A, J?nemann A, Turski WA, Wnorowski A, J??wiak K, Paduch R, Okuno E, Moneta-Wielgo? J, Chor?giewicz T, Maciejewski R, Rejdak R
Molecular vision23364-371(2017)

Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate ?-lyase activity and can transaminate L-selenomethionine.
Pinto JT, Krasnikov BF, Alcutt S, Jones ME, Dorai T, Villar MT, Artigues A, Li J, Cooper AJ
The Journal of biological chemistry289(45)30950-61(2014 Nov)

The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes.
Claes S, Myint AM, Domschke K, Del-Favero J, Entrich K, Engelborghs S, De Deyn P, Mueller N, Baune B, Rothermundt M
Psychiatry research188(3)355-60(2011 Aug)

Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.
Yu P, Li Z, Zhang L, Tagle DA, Cai T
Gene365111-8(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

human KAT III/CCBL2 possesses cysteine S-conjugate beta-lyase activity, as does mouse KAT II
Title: Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate ?-lyase activity and can transaminate L-selenomethionine.

The haplotype of KAT III gene CGCTCT may have effect on the function of this enzyme in formation of kynurenic acid in some patients with major depressive episodes.
Title: The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Using shotgun mass spectrometry, it was found that this protein is differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Title: Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

The following KYAT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KYAT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15421	NM_001349447.1 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15421	NM_001008662.2 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15511	NM_001349448.1 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15511	NM_001008661.3 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu101026	NM_001349449.1 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu101026	NM_001349450.1 Latest version!	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu15511	NM_001008661.2	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KYAT3 ( NM_001008662.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008662.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15421
Clone ID Related Accession (Same CDS sequence)	NM_001008662.2 , NM_001349447.1
Accession Version	NM_001008662.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424120.1, AK057176.1 and AI478599.1. On Jun 26, 2009 this sequence version replaced NM_001008662.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' region and uses a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform (2). ##Evidence-Data-START## Transcript exon combination :: SRR1163657.517106.1, AK057176.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGA AATTCACAAA TGCAAAACGG ATTGAAGGAC TTGATAGTAA TGTGTGGATT 
GAATTTACCA AATTGGCTGC AGACCCTTCT GTTGTGAATC TTGGCCAAGG CTTTCCAGAT 
ATATCCCCTC CTACATATGT AAAAGAAGAA TTATCAAAGA TTGCAGCAAT CGATAGCCTG 
AATCAGTATA CACGAGGCTT TGGCCATCCA TCACTTGTGA AAGCTCTGTC CTATCTGTAT 
GAAAAGCTTT ATCAAAAGCA AATTGATTCA AATAAAGAAA TCCTTGTGAC AGTAGGAGCA 
TATGGATCTC TTTTTAACAC CATTCAAGCA TTAATTGATG AGGGAGATGA AGTCATACTA 
ATAGTGCCTT TCTATGACTG CTATGAGCCC ATGGTGAGAA TGGCTGGAGC AACACCTGTT 
TTTATTCCCC TGAGATCTAA ACCTGTTTAT GGAAAAAGAT GGTCTAGTTC TGACTGGACA 
TTAGATCCTC AAGAACTGGA AAGTAAATTT AATTCCAAAA CCAAAGCTAT TATACTAAAT 
ACTCCACATA ACCCACTTGG CAAGGTGTAT AACAGAGAGG AACTGCAAGT AATTGCTGAC 
CTTTGCATCA AATATGACAC ACTCTGCATC AGCGATGAGG TTTATGAATG GCTTGTATAT 
TCTGGAAATA AGCACTTAAA AATAGCTACT TTTCCAGGTA TGTGGGAGAG AACAATAACA 
ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA ACTGGCTGGA AGCTTGGCTG GTCCATTGGT 
CCAAATCATT TGATAAAACA TTTACAGACA GTTCAACAAA ACACGATTTA TACTTGTGCA 
ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT TTCTGGATTG ACATCAAGCG CATGGATGAC 
CCAGAATGTT ACTTTAATTC TTTGCCAAAA GAGTTAGAAG TAAAAAGAGA TCGGATGGTA 
CGTTTACTTG AAAGTGTTGG CCTAAAACCC ATAGTTCCTG ATGGAGGATA CTTCATCATC 
GCTGATGTGT CTTTGCTAGA TCCAGACCTC TCTGATATGA AGAATAATGA GCCTTATGAC 
TATAAGTTTG TGAAATGGAT GACTAAACAT AAGAAACTAT CAGCCATCCC CGTTTCAGCA 
TTCTGTAACT CAGAGACTAA ATCACAGTTT GAGAAGTTTG TGCGTTTTTG CTTCATTAAA 
AAAGACAGCA CACTGGATGC TGCTGAAGAA ATCATCAAGG CATGGAGTGT ACAGAAGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008662.1
CDS	380..1642
Translation	MSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001008662.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008662.2

ORF Insert Sequence:

ATGTCACTGA AATTCACAAA TGCAAAACGG ATTGAAGGAC TTGATAGTAA TGTGTGGATT 
GAATTTACCA AATTGGCTGC AGACCCTTCT GTTGTGAATC TTGGCCAAGG CTTTCCAGAT 
ATATCCCCTC CTACATATGT AAAAGAAGAA TTATCAAAGA TTGCAGCAAT CGATAGCCTG 
AATCAGTATA CACGAGGCTT TGGCCATCCA TCACTTGTGA AAGCTCTGTC CTATCTGTAT 
GAAAAGCTTT ATCAAAAGCA AATTGATTCA AATAAAGAAA TCCTTGTGAC AGTAGGAGCA 
TATGGATCTC TTTTTAACAC CATTCAAGCA TTAATTGATG AGGGAGATGA AGTCATACTA 
ATAGTGCCTT TCTATGACTG CTATGAGCCC ATGGTGAGAA TGGCTGGAGC AACACCTGTT 
TTTATTCCCC TGAGATCTAA ACCTGTTTAT GGAAAAAGAT GGTCTAGTTC TGACTGGACA 
TTAGATCCTC AAGAACTGGA AAGTAAATTT AATTCCAAAA CCAAAGCTAT TATACTAAAT 
ACTCCACATA ACCCACTTGG CAAGGTGTAT AACAGAGAGG AACTGCAAGT AATTGCTGAC 
CTTTGCATCA AATATGACAC ACTCTGCATC AGCGATGAGG TTTATGAATG GCTTGTATAT 
TCTGGAAATA AGCACTTAAA AATAGCTACT TTTCCAGGTA TGTGGGAGAG AACAATAACA 
ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA ACTGGCTGGA AGCTTGGCTG GTCCATTGGT 
CCAAATCATT TGATAAAACA TTTACAGACA GTTCAACAAA ACACGATTTA TACTTGTGCA 
ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT TTCTGGATTG ACATCAAGCG CATGGATGAC 
CCAGAATGTT ACTTTAATTC TTTGCCAAAA GAGTTAGAAG TAAAAAGAGA TCGGATGGTA 
CGTTTACTTG AAAGTGTTGG CCTAAAACCC ATAGTTCCTG ATGGAGGATA CTTCATCATC 
GCTGATGTGT CTTTGCTAGA TCCAGACCTC TCTGATATGA AGAATAATGA GCCTTATGAC 
TATAAGTTTG TGAAATGGAT GACTAAACAT AAGAAACTAT CAGCCATCCC CGTTTCAGCA 
TTCTGTAACT CAGAGACTAA ATCACAGTTT GAGAAGTTTG TGCGTTTTTG CTTCATTAAA 
AAAGACAGCA CACTGGATGC TGCTGAAGAA ATCATCAAGG CATGGAGTGT ACAGAAGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001349447.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336376.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15421
Clone ID Related Accession (Same CDS sequence)	NM_001008662.2 , NM_001349447.1
Accession Version	NM_001349447.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-14
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139416.5 and AL445991.15. Transcript Variant: This variant (3) lacks a segment in the 5' UTR, lacks an alternate exon in the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. Variants 2 and 3 encode the same isoform (2). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.192754.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGA AATTCACAAA TGCAAAACGG ATTGAAGGAC TTGATAGTAA TGTGTGGATT 
GAATTTACCA AATTGGCTGC AGACCCTTCT GTTGTGAATC TTGGCCAAGG CTTTCCAGAT 
ATATCCCCTC CTACATATGT AAAAGAAGAA TTATCAAAGA TTGCAGCAAT CGATAGCCTG 
AATCAGTATA CACGAGGCTT TGGCCATCCA TCACTTGTGA AAGCTCTGTC CTATCTGTAT 
GAAAAGCTTT ATCAAAAGCA AATTGATTCA AATAAAGAAA TCCTTGTGAC AGTAGGAGCA 
TATGGATCTC TTTTTAACAC CATTCAAGCA TTAATTGATG AGGGAGATGA AGTCATACTA 
ATAGTGCCTT TCTATGACTG CTATGAGCCC ATGGTGAGAA TGGCTGGAGC AACACCTGTT 
TTTATTCCCC TGAGATCTAA ACCTGTTTAT GGAAAAAGAT GGTCTAGTTC TGACTGGACA 
TTAGATCCTC AAGAACTGGA AAGTAAATTT AATTCCAAAA CCAAAGCTAT TATACTAAAT 
ACTCCACATA ACCCACTTGG CAAGGTGTAT AACAGAGAGG AACTGCAAGT AATTGCTGAC 
CTTTGCATCA AATATGACAC ACTCTGCATC AGCGATGAGG TTTATGAATG GCTTGTATAT 
TCTGGAAATA AGCACTTAAA AATAGCTACT TTTCCAGGTA TGTGGGAGAG AACAATAACA 
ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA ACTGGCTGGA AGCTTGGCTG GTCCATTGGT 
CCAAATCATT TGATAAAACA TTTACAGACA GTTCAACAAA ACACGATTTA TACTTGTGCA 
ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT TTCTGGATTG ACATCAAGCG CATGGATGAC 
CCAGAATGTT ACTTTAATTC TTTGCCAAAA GAGTTAGAAG TAAAAAGAGA TCGGATGGTA 
CGTTTACTTG AAAGTGTTGG CCTAAAACCC ATAGTTCCTG ATGGAGGATA CTTCATCATC 
GCTGATGTGT CTTTGCTAGA TCCAGACCTC TCTGATATGA AGAATAATGA GCCTTATGAC 
TATAAGTTTG TGAAATGGAT GACTAAACAT AAGAAACTAT CAGCCATCCC CGTTTCAGCA 
TTCTGTAACT CAGAGACTAA ATCACAGTTT GAGAAGTTTG TGCGTTTTTG CTTCATTAAA 
AAAGACAGCA CACTGGATGC TGCTGAAGAA ATCATCAAGG CATGGAGTGT ACAGAAGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336376.1
CDS	242..1504
Translation	MSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001349447.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349447.1

ORF Insert Sequence:

ATGTCACTGA AATTCACAAA TGCAAAACGG ATTGAAGGAC TTGATAGTAA TGTGTGGATT 
GAATTTACCA AATTGGCTGC AGACCCTTCT GTTGTGAATC TTGGCCAAGG CTTTCCAGAT 
ATATCCCCTC CTACATATGT AAAAGAAGAA TTATCAAAGA TTGCAGCAAT CGATAGCCTG 
AATCAGTATA CACGAGGCTT TGGCCATCCA TCACTTGTGA AAGCTCTGTC CTATCTGTAT 
GAAAAGCTTT ATCAAAAGCA AATTGATTCA AATAAAGAAA TCCTTGTGAC AGTAGGAGCA 
TATGGATCTC TTTTTAACAC CATTCAAGCA TTAATTGATG AGGGAGATGA AGTCATACTA 
ATAGTGCCTT TCTATGACTG CTATGAGCCC ATGGTGAGAA TGGCTGGAGC AACACCTGTT 
TTTATTCCCC TGAGATCTAA ACCTGTTTAT GGAAAAAGAT GGTCTAGTTC TGACTGGACA 
TTAGATCCTC AAGAACTGGA AAGTAAATTT AATTCCAAAA CCAAAGCTAT TATACTAAAT 
ACTCCACATA ACCCACTTGG CAAGGTGTAT AACAGAGAGG AACTGCAAGT AATTGCTGAC 
CTTTGCATCA AATATGACAC ACTCTGCATC AGCGATGAGG TTTATGAATG GCTTGTATAT 
TCTGGAAATA AGCACTTAAA AATAGCTACT TTTCCAGGTA TGTGGGAGAG AACAATAACA 
ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA ACTGGCTGGA AGCTTGGCTG GTCCATTGGT 
CCAAATCATT TGATAAAACA TTTACAGACA GTTCAACAAA ACACGATTTA TACTTGTGCA 
ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT TTCTGGATTG ACATCAAGCG CATGGATGAC 
CCAGAATGTT ACTTTAATTC TTTGCCAAAA GAGTTAGAAG TAAAAAGAGA TCGGATGGTA 
CGTTTACTTG AAAGTGTTGG CCTAAAACCC ATAGTTCCTG ATGGAGGATA CTTCATCATC 
GCTGATGTGT CTTTGCTAGA TCCAGACCTC TCTGATATGA AGAATAATGA GCCTTATGAC 
TATAAGTTTG TGAAATGGAT GACTAAACAT AAGAAACTAT CAGCCATCCC CGTTTCAGCA 
TTCTGTAACT CAGAGACTAA ATCACAGTTT GAGAAGTTTG TGCGTTTTTG CTTCATTAAA 
AAAGACAGCA CACTGGATGC TGCTGAAGAA ATCATCAAGG CATGGAGTGT ACAGAAGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001349448.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336377.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu15511
Clone ID Related Accession (Same CDS sequence)	NM_001349448.1 , NM_001008661.3 , NM_001008661.2
Accession Version	NM_001349448.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139416.5 and AL445991.15. Transcript Variant: This variant (4) lacks a segment in the 5' UTR compared to variant 1. Variants 1 and 4 encode the same isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.286749.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336377.1
CDS	250..1614
Translation	MFLAQRSLCSLSGRAKFLKTISSSKILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001349448.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349448.1

ORF Insert Sequence:

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001008661.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008661.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15511
Clone ID Related Accession (Same CDS sequence)	NM_001349448.1 , NM_001008661.3 , NM_001008661.2
Accession Version	NM_001008661.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY028624.1. On Nov 24, 2018 this sequence version replaced NM_001008661.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AY028624.1, SRR5189652.100848.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000260508.9/ ENSP00000260508.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008661.1
CDS	47..1411
Translation	MFLAQRSLCSLSGRAKFLKTISSSKILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001008661.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008661.3

ORF Insert Sequence:

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001008661.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008661.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15511
Clone ID Related Accession (Same CDS sequence)	NM_001349448.1 , NM_001008661.3 , NM_001008661.2
Accession Version	NM_001008661.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424120.1, AY028624.1 and AI478599.1. On Jun 26, 2009 this sequence version replaced NM_001008661.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AY028624.1, SRR1163657.105628.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008661.1
CDS	378..1742
Translation	MFLAQRSLCSLSGRAKFLKTISSSKILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001008661.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008661.2

ORF Insert Sequence:

ATGTTTTTGG CCCAGAGGAG CCTCTGCTCT CTTAGCGGTA GAGCAAAATT CCTGAAGACA 
ATTTCTTCTT CCAAAATCCT CGGATTCTCT ACTTCTGCTA AAATGTCACT GAAATTCACA 
AATGCAAAAC GGATTGAAGG ACTTGATAGT AATGTGTGGA TTGAATTTAC CAAATTGGCT 
GCAGACCCTT CTGTTGTGAA TCTTGGCCAA GGCTTTCCAG ATATATCCCC TCCTACATAT 
GTAAAAGAAG AATTATCAAA GATTGCAGCA ATCGATAGCC TGAATCAGTA TACACGAGGC 
TTTGGCCATC CATCACTTGT GAAAGCTCTG TCCTATCTGT ATGAAAAGCT TTATCAAAAG 
CAAATTGATT CAAATAAAGA AATCCTTGTG ACAGTAGGAG CATATGGATC TCTTTTTAAC 
ACCATTCAAG CATTAATTGA TGAGGGAGAT GAAGTCATAC TAATAGTGCC TTTCTATGAC 
TGCTATGAGC CCATGGTGAG AATGGCTGGA GCAACACCTG TTTTTATTCC CCTGAGATCT 
AAACCTGTTT ATGGAAAAAG ATGGTCTAGT TCTGACTGGA CATTAGATCC TCAAGAACTG 
GAAAGTAAAT TTAATTCCAA AACCAAAGCT ATTATACTAA ATACTCCACA TAACCCACTT 
GGCAAGGTGT ATAACAGAGA GGAACTGCAA GTAATTGCTG ACCTTTGCAT CAAATATGAC 
ACACTCTGCA TCAGCGATGA GGTTTATGAA TGGCTTGTAT ATTCTGGAAA TAAGCACTTA 
AAAATAGCTA CTTTTCCAGG TATGTGGGAG AGAACAATAA CAATAGGAAG TGCTGGAAAG 
ACTTTCAGTG TAACTGGCTG GAAGCTTGGC TGGTCCATTG GTCCAAATCA TTTGATAAAA 
CATTTACAGA CAGTTCAACA AAACACGATT TATACTTGTG CAACTCCTTT ACAGGAAGCC 
TTGGCTCAAG CTTTCTGGAT TGACATCAAG CGCATGGATG ACCCAGAATG TTACTTTAAT 
TCTTTGCCAA AAGAGTTAGA AGTAAAAAGA GATCGGATGG TACGTTTACT TGAAAGTGTT 
GGCCTAAAAC CCATAGTTCC TGATGGAGGA TACTTCATCA TCGCTGATGT GTCTTTGCTA 
GATCCAGACC TCTCTGATAT GAAGAATAAT GAGCCTTATG ACTATAAGTT TGTGAAATGG 
ATGACTAAAC ATAAGAAACT ATCAGCCATC CCCGTTTCAG CATTCTGTAA CTCAGAGACT 
AAATCACAGT TTGAGAAGTT TGTGCGTTTT TGCTTCATTA AAAAAGACAG CACACTGGAT 
GCTGCTGAAG AAATCATCAA GGCATGGAGT GTACAGAAGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001349449.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336378.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu101026
Clone ID Related Accession (Same CDS sequence)	NM_001349449.1 , NM_001349450.1
Accession Version	NM_001349449.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139416.5 and AL445991.15. Transcript Variant: This variant (5) has a shorter 5' UTR, lacks an exon in the 5' region and contains an alternate exon, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus than isoform 1. Variants 5 and 6 encode the same isoform (3). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.123790.1, SRR1660807.196461.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGAGAA TGGCTGGAGC AACACCTGTT TTTATTCCCC TGAGATCTAA ACCTGTTTAT 
GGAAAAAGAT GGTCTAGTTC TGACTGGACA TTAGATCCTC AAGAACTGGA AAGTAAATTT 
AATTCCAAAA CCAAAGCTAT TATACTAAAT ACTCCACATA ACCCACTTGG CAAGGTGTAT 
AACAGAGAGG AACTGCAAGT AATTGCTGAC CTTTGCATCA AATATGACAC ACTCTGCATC 
AGCGATGAGG TTTATGAATG GCTTGTATAT TCTGGAAATA AGCACTTAAA AATAGCTACT 
TTTCCAGGTA TGTGGGAGAG AACAATAACA ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA 
ACTGGCTGGA AGCTTGGCTG GTCCATTGGT CCAAATCATT TGATAAAACA TTTACAGACA 
GTTCAACAAA ACACGATTTA TACTTGTGCA ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT 
TTCTGGATTG ACATCAAGCG CATGGATGAC CCAGAATGTT ACTTTAATTC TTTGCCAAAA 
GAGTTAGAAG TAAAAAGAGA TCGGATGGTA CGTTTACTTG AAAGTGTTGG CCTAAAACCC 
ATAGTTCCTG ATGGAGGATA CTTCATCATC GCTGATGTGT CTTTGCTAGA TCCAGACCTC 
TCTGATATGA AGAATAATGA GCCTTATGAC TATAAGTTTG TGAAATGGAT GACTAAACAT 
AAGAAACTAT CAGCCATCCC CGTTTCAGCA TTCTGTAACT CAGAGACTAA ATCACAGTTT 
GAGAAGTTTG TGCGTTTTTG CTTCATTAAA AAAGACAGCA CACTGGATGC TGCTGAAGAA 
ATCATCAAGG CATGGAGTGT ACAGAAGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336378.1
CDS	715..1587
Translation	MVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001349449.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349449.1

ORF Insert Sequence:

ATGGTGAGAA TGGCTGGAGC AACACCTGTT TTTATTCCCC TGAGATCTAA ACCTGTTTAT 
GGAAAAAGAT GGTCTAGTTC TGACTGGACA TTAGATCCTC AAGAACTGGA AAGTAAATTT 
AATTCCAAAA CCAAAGCTAT TATACTAAAT ACTCCACATA ACCCACTTGG CAAGGTGTAT 
AACAGAGAGG AACTGCAAGT AATTGCTGAC CTTTGCATCA AATATGACAC ACTCTGCATC 
AGCGATGAGG TTTATGAATG GCTTGTATAT TCTGGAAATA AGCACTTAAA AATAGCTACT 
TTTCCAGGTA TGTGGGAGAG AACAATAACA ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA 
ACTGGCTGGA AGCTTGGCTG GTCCATTGGT CCAAATCATT TGATAAAACA TTTACAGACA 
GTTCAACAAA ACACGATTTA TACTTGTGCA ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT 
TTCTGGATTG ACATCAAGCG CATGGATGAC CCAGAATGTT ACTTTAATTC TTTGCCAAAA 
GAGTTAGAAG TAAAAAGAGA TCGGATGGTA CGTTTACTTG AAAGTGTTGG CCTAAAACCC 
ATAGTTCCTG ATGGAGGATA CTTCATCATC GCTGATGTGT CTTTGCTAGA TCCAGACCTC 
TCTGATATGA AGAATAATGA GCCTTATGAC TATAAGTTTG TGAAATGGAT GACTAAACAT 
AAGAAACTAT CAGCCATCCC CGTTTCAGCA TTCTGTAACT CAGAGACTAA ATCACAGTTT 
GAGAAGTTTG TGCGTTTTTG CTTCATTAAA AAAGACAGCA CACTGGATGC TGCTGAAGAA 
ATCATCAAGG CATGGAGTGT ACAGAAGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KYAT3 ( NM_001349450.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336379.1 Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu101026
Clone ID Related Accession (Same CDS sequence)	NM_001349449.1 , NM_001349450.1
Accession Version	NM_001349450.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	kynurenine--oxoglutarate transaminase 3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA943114.1, AL833593.1, AY028624.1 and AI478599.1. Transcript Variant: This variant (6) has a shorter 5' UTR, contains an alternate exon in the 5' region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus than isoform 1. Variants 5 and 6 encode the same isoform (3). ##Evidence-Data-START## Transcript exon combination :: SRR1660805.184820.1, AL833593.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGAGAA TGGCTGGAGC AACACCTGTT TTTATTCCCC TGAGATCTAA ACCTGTTTAT 
GGAAAAAGAT GGTCTAGTTC TGACTGGACA TTAGATCCTC AAGAACTGGA AAGTAAATTT 
AATTCCAAAA CCAAAGCTAT TATACTAAAT ACTCCACATA ACCCACTTGG CAAGGTGTAT 
AACAGAGAGG AACTGCAAGT AATTGCTGAC CTTTGCATCA AATATGACAC ACTCTGCATC 
AGCGATGAGG TTTATGAATG GCTTGTATAT TCTGGAAATA AGCACTTAAA AATAGCTACT 
TTTCCAGGTA TGTGGGAGAG AACAATAACA ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA 
ACTGGCTGGA AGCTTGGCTG GTCCATTGGT CCAAATCATT TGATAAAACA TTTACAGACA 
GTTCAACAAA ACACGATTTA TACTTGTGCA ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT 
TTCTGGATTG ACATCAAGCG CATGGATGAC CCAGAATGTT ACTTTAATTC TTTGCCAAAA 
GAGTTAGAAG TAAAAAGAGA TCGGATGGTA CGTTTACTTG AAAGTGTTGG CCTAAAACCC 
ATAGTTCCTG ATGGAGGATA CTTCATCATC GCTGATGTGT CTTTGCTAGA TCCAGACCTC 
TCTGATATGA AGAATAATGA GCCTTATGAC TATAAGTTTG TGAAATGGAT GACTAAACAT 
AAGAAACTAT CAGCCATCCC CGTTTCAGCA TTCTGTAACT CAGAGACTAA ATCACAGTTT 
GAGAAGTTTG TGCGTTTTTG CTTCATTAAA AAAGACAGCA CACTGGATGC TGCTGAAGAA 
ATCATCAAGG CATGGAGTGT ACAGAAGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336379.1
CDS	815..1687
Translation	MVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS

Target ORF information:

RefSeq Version	NM_001349450.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kynurenine aminotransferase 3 (KYAT3), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349450.1

ORF Insert Sequence:

ATGGTGAGAA TGGCTGGAGC AACACCTGTT TTTATTCCCC TGAGATCTAA ACCTGTTTAT 
GGAAAAAGAT GGTCTAGTTC TGACTGGACA TTAGATCCTC AAGAACTGGA AAGTAAATTT 
AATTCCAAAA CCAAAGCTAT TATACTAAAT ACTCCACATA ACCCACTTGG CAAGGTGTAT 
AACAGAGAGG AACTGCAAGT AATTGCTGAC CTTTGCATCA AATATGACAC ACTCTGCATC 
AGCGATGAGG TTTATGAATG GCTTGTATAT TCTGGAAATA AGCACTTAAA AATAGCTACT 
TTTCCAGGTA TGTGGGAGAG AACAATAACA ATAGGAAGTG CTGGAAAGAC TTTCAGTGTA 
ACTGGCTGGA AGCTTGGCTG GTCCATTGGT CCAAATCATT TGATAAAACA TTTACAGACA 
GTTCAACAAA ACACGATTTA TACTTGTGCA ACTCCTTTAC AGGAAGCCTT GGCTCAAGCT 
TTCTGGATTG ACATCAAGCG CATGGATGAC CCAGAATGTT ACTTTAATTC TTTGCCAAAA 
GAGTTAGAAG TAAAAAGAGA TCGGATGGTA CGTTTACTTG AAAGTGTTGG CCTAAAACCC 
ATAGTTCCTG ATGGAGGATA CTTCATCATC GCTGATGTGT CTTTGCTAGA TCCAGACCTC 
TCTGATATGA AGAATAATGA GCCTTATGAC TATAAGTTTG TGAAATGGAT GACTAAACAT 
AAGAAACTAT CAGCCATCCC CGTTTCAGCA TTCTGTAACT CAGAGACTAA ATCACAGTTT 
GAGAAGTTTG TGCGTTTTTG CTTCATTAAA AAAGACAGCA CACTGGATGC TGCTGAAGAA 
ATCATCAAGG CATGGAGTGT ACAGAAGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.
Molecular vision23364-371(2017)
Matysik-Wo?niak A,J?nemann A,Turski WA,Wnorowski A,J??wiak K,Paduch R,Okuno E,Moneta-Wielgo? J,Chor?giewicz T,Maciejewski R,Rejdak R

Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate ?-lyase activity and can transaminate L-selenomethionine.
The Journal of biological chemistry289(45)30950-61(2014 Nov)
Pinto JT,Krasnikov BF,Alcutt S,Jones ME,Dorai T,Villar MT,Artigues A,Li J,Cooper AJ

The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes.
Psychiatry research188(3)355-60(2011 Aug)
Claes S,Myint AM,Domschke K,Del-Favero J,Entrich K,Engelborghs S,De Deyn P,Mueller N,Baune B,Rothermundt M

Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.
Gene365111-8(2006 Jan)
Yu P,Li Z,Zhang L,Tagle DA,Cai T

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

KYAT3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報