PCDHGB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCDHGB2
Entrez Gene ID	56103
Full Name	protocadherin gamma subfamily B, 2
Synonyms	PCDH-GAMMA-B2
General protein information	Preferred Names protocadherin gamma subfamily B, 2 Names protocadherin gamma-B2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.3
Summary	This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].
Disorder MIM:	606300

mRNA and Protein(s)

mRNA	Protein	Name
NM_032096.1	NP_115267.1	protocadherin gamma-B2 isoform 2 precursor
NM_018923.2	NP_061746.1	protocadherin gamma-B2 isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PCDHGB2	NP_061746.1
Pan troglodytes (chimpanzee)	PCDHGB2	NP_001076031.1
Canis lupus familiaris (dog)	PCDHGB2	XP_003638957.2
Mus musculus (house mouse)	Pcdhgb2	NP_291053.1
	LOC699795	XP_001088244.2

Gene Ontology
Bibliography

Related articles in PubMed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M, Noonan JP, Zhang MQ, Myers RM, Maniatis T
Genome research11(3)389-404(2001 Mar)

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Nollet F, Kools P, van Roy F
Journal of molecular biology299(3)551-72(2000 Jun)

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.
Yagi T, Takeichi M
Genes & development14(10)1169-80(2000 May)

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.
Wu Q, Maniatis T
Proceedings of the National Academy of Sciences of the United States of America97(7)3124-9(2000 Mar)

A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Wu Q, Maniatis T
Cell97(6)779-90(1999 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PCDHGB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCDHGB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29670	NM_018923.2 Latest version!	Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$469.50-$657.30 $939.00
OHu29795	NM_032096.1 Latest version!	Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCDHGB2 ( NM_018923.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061746.1 Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29670
Clone ID Related Accession (Same CDS sequence)	NM_018923.2
Accession Version	NM_018923.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	protocadherin gamma-B2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF152331.1. On May 31, 2001 this sequence version replaced NM_018923.1. Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF152331.1, SRR1660805.149405.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCGA GCTCAGGGAG GTGCGGGCTG GTGCGGTGGC TGCAGGTACT GTTGCCCTTC 
CTGTTGTCTT TGTTCCCCGG GGCTCTCCCA GTCCAGATCC GCTATTCAAT TCCAGAGGAG 
CTGGCCAAAA ACTCGGTCGT AGGAAACCTC GCCAAGGATC TGGGGCTCAG CGTCCGGGAC 
TTGCCAGCCC GGAAGCTGCG GGTTAGCGCG GAGAAGGAAT ATTTCACAGT AAACCCAGAA 
AGCGGAGACT TACTTGTGAG TGACAGAATA GACCGAGAAC AGATATGCGG GAAGCAGCCT 
CTGTGTGTTC TGGATTTCGA TACTGTCGCT GAAAATCCAC TAAATATTTT CTACATAGCA 
GTAATTGTGC AGGATATAAA TGATAATACC CCGCTATTCA AACAGACTAA GATTAATTTA 
AAAATTGGCG AATCCACTAA GCCAGGTACA ACATTTCCAC TTGACCCAGC CCTGGATTCA 
GATGTTGGTC CTAACTCACT ACAAAGATAC CACCTTAATG ACAACGAGTA CTTTGATCTC 
GCTGAGAAAC AGACTCCAGA TGGTCGTAAA TATCCTGAGT TGATTCTAAA ACACTCTCTG 
GACAGAGAAG AGCACAGTTT ACATCAATTG GTCCTCACAG CTGTGGATGG CGGAGACCCA 
CCTCAAAGTG GCACGACCCA AATCCGAATC AAAGTCACGG ATGCCAACGA TAACCCTCCA 
GTGTTCAGCC AGGACGTGTA CAGGGTCACC CTGAGGGAGG ACGTGCCGCC GGGCTTCTTT 
GTGCTTCAAG TGACAGCCAC CGACCGGGAT GAAGGCATAA ACGCAGAGAT CACCTACTCC 
TTTCATAATG TGGACGAACA AGTGAAACAC TTTTTCAACT TAAATGAAAA AACAGGAGAA 
ATCACGACAA AGGATGATTT GGATTTTGAG ATTGCAAGTA GTTACACTCT GAGTATCGAA 
GCAAAAGATC CTGGAGATCT AGCAGCCCAC TGCAGTATCC AAGTTGAAAT TCTTGATGAC 
AACGATTGTG CACCTGAAGT TATTGTGACT TCAGTATCTA CTCCCCTACC GGAGGATTCG 
CCACCAGGAA CAGTGATCGC CTTGATAAAA ACGAGAGACA GAGACTCTGG AGAAAATGGA 
GAAGTTTACT GCCAAGTGTT GGGAAATGCC AAGTTTATTT TGAAATCTTC CTCAAAGAAC 
TATTACAAAC TAGTGACAGA CGGCGCTCTG GACCGGGAGG AGATCCCAGA ATACAATCTC 
ACCATCACAG CCACCGACGG GGGCAAGCCG CCCCTCTCCT CCAGCATAAT TGTCACCCTG 
CACATCTCCG ACGTCAACGA TAATGCCCCA GTTTTCCAAC AGACTTCCTA CATGGTTCAC 
GTGGCAGAGA ACAATCCTCC TGGCGCCTCT ATCGCTCAAA TCAGTGCCTC TGACCCTGAC 
TTGGGCCCCA GTGGCCAAGT TTCCTACTCC ATCGTAGCGA GCGACCTGAA GCCGCGGGAG 
ATTTTATCCT ACGTGTCCGT GAGCGCGCAG AGCGGGGTGG TGTTCGCGCA GCGCGCCTTC 
GATCATGAGC AGCTGCGCGC CTTCGAGCTC ACACTGCAGG CCCGCGACCA GGGCTCGCCC 
GCGCTCAGCG CCAACGTGAG CCTGCGCGTG TTAGTGGGCG ACCTCAATGA CAATGCGCCA 
CGGGTGCTGT ACCCCGCGCT GGGGCCTGAT GGCTCCGCCC TCTTCGATAT GGTGCCACGC 
GCCGCAGAGC CCGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGCAGA CTCAGGACAC 
AACGCTTGGC TGTCCTACCA CGTGCTGCAG GCCAGCGAGC CCGGGCTCTT CAGCCTGGGG 
TTGCGCACGG GTGAGGTGCG CACAGCGCGT GCCTTGGGCG ACAGGGACGC GGCCCGCCAG 
CGCCTGCTGG TCGCTGTGCG TGATGGAGGA CAGCCGCCAC TCTCCGCTAC GGCCACGCTG 
CACCTAATCT TCGCGGATAG CCTGCAAGAG GTATTGCCAG ACCTCAGCGA CCGCCGGGAG 
CCCTCTGACC CCCAGGCAAA ACTGCAGTTT TACCTGGTTG TGGCCTTGGC CTTGATCTCA 
GTGCTCTTCT TCCTCGCGGT GATTCTGGCA ATCTCCCTGC GCCTGCGACT CTCTTCCAGG 
TCAGATGCTT GGGACTGTTT TCAGCCTGGT CTCAGCTCCA AGCCTGGACC TGGGGTTCTC 
CCCAATTACA GTGAGGGTAC ATTGCCCTAT TCCTACAACC TGTGTGTTGC CTCACAATCA 
GCCAAGACAG AGTTCAATTT TCTGAACATA ACCCCGGAAT TGGTTCCCGC GCAAGATCTC 
GTCTGTGACA ATGCCTCTTG GGAACAAAAT ACAAATCATG GAGCCGCTGG GGTCCCTTTT 
GCCTCAGATA CTATTTTGAA GCAAGCCCCG CCCAACACGG ACTGGCGTTT CTCTCAGGCC 
CAGAGACCCG GCACCAGCGG CTCCCAAAAT GGCGATGACA CCGGCACCTG GCCCAACAAC 
CAGTTTGACA CAGAGATGCT GCAAGCCATG ATCTTGGCGT CCGCCAGTGA AGCTGCTGAT 
GGGAGCTCCA CCCTGGGAGG GGGTGCCGGC ACCATGGGAT TGAGCGCCCG CTACGGACCC 
CAGTTCACCC TGCAGCACGT GCCCGACTAC CGCCAGAATG TCTACATCCC AGGCAGCAAT 
GCCACACTGA CCAACGCAGC TGGCAAGCGG GATGGCAAGG CCCCAGCAGG TGGCAATGGC 
AACAAGAAGA AGTCGGGCAA GAAGGAGAAG AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061746.1
CDS	1..2796
Translation	MKASSGRCGLVRWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLRLRLSSRSDAWDCFQPGLSSKPGPGVLPNYSEGTLPYSYNLCVASQSAKTEFNFLNITPELVPAQDLVCDNASWEQNTNHGAAGVPFASDTILKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Target ORF information:

RefSeq Version	NM_018923.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018923.2

ORF Insert Sequence:

ATGAAAGCGA GCTCAGGGAG GTGCGGGCTG GTGCGGTGGC TGCAGGTACT GTTGCCCTTC 
CTGTTGTCTT TGTTCCCCGG GGCTCTCCCA GTCCAGATCC GCTATTCAAT TCCAGAGGAG 
CTGGCCAAAA ACTCGGTCGT AGGAAACCTC GCCAAGGATC TGGGGCTCAG CGTCCGGGAC 
TTGCCAGCCC GGAAGCTGCG GGTTAGCGCG GAGAAGGAAT ATTTCACAGT AAACCCAGAA 
AGCGGAGACT TACTTGTGAG TGACAGAATA GACCGAGAAC AGATATGCGG GAAGCAGCCT 
CTGTGTGTTC TGGATTTCGA TACTGTCGCT GAAAATCCAC TAAATATTTT CTACATAGCA 
GTAATTGTGC AGGATATAAA TGATAATACC CCGCTATTCA AACAGACTAA GATTAATTTA 
AAAATTGGCG AATCCACTAA GCCAGGTACA ACATTTCCAC TTGACCCAGC CCTGGATTCA 
GATGTTGGTC CTAACTCACT ACAAAGATAC CACCTTAATG ACAACGAGTA CTTTGATCTC 
GCTGAGAAAC AGACTCCAGA TGGTCGTAAA TATCCTGAGT TGATTCTAAA ACACTCTCTG 
GACAGAGAAG AGCACAGTTT ACATCAATTG GTCCTCACAG CTGTGGATGG CGGAGACCCA 
CCTCAAAGTG GCACGACCCA AATCCGAATC AAAGTCACGG ATGCCAACGA TAACCCTCCA 
GTGTTCAGCC AGGACGTGTA CAGGGTCACC CTGAGGGAGG ACGTGCCGCC GGGCTTCTTT 
GTGCTTCAAG TGACAGCCAC CGACCGGGAT GAAGGCATAA ACGCAGAGAT CACCTACTCC 
TTTCATAATG TGGACGAACA AGTGAAACAC TTTTTCAACT TAAATGAAAA AACAGGAGAA 
ATCACGACAA AGGATGATTT GGATTTTGAG ATTGCAAGTA GTTACACTCT GAGTATCGAA 
GCAAAAGATC CTGGAGATCT AGCAGCCCAC TGCAGTATCC AAGTTGAAAT TCTTGATGAC 
AACGATTGTG CACCTGAAGT TATTGTGACT TCAGTATCTA CTCCCCTACC GGAGGATTCG 
CCACCAGGAA CAGTGATCGC CTTGATAAAA ACGAGAGACA GAGACTCTGG AGAAAATGGA 
GAAGTTTACT GCCAAGTGTT GGGAAATGCC AAGTTTATTT TGAAATCTTC CTCAAAGAAC 
TATTACAAAC TAGTGACAGA CGGCGCTCTG GACCGGGAGG AGATCCCAGA ATACAATCTC 
ACCATCACAG CCACCGACGG GGGCAAGCCG CCCCTCTCCT CCAGCATAAT TGTCACCCTG 
CACATCTCCG ACGTCAACGA TAATGCCCCA GTTTTCCAAC AGACTTCCTA CATGGTTCAC 
GTGGCAGAGA ACAATCCTCC TGGCGCCTCT ATCGCTCAAA TCAGTGCCTC TGACCCTGAC 
TTGGGCCCCA GTGGCCAAGT TTCCTACTCC ATCGTAGCGA GCGACCTGAA GCCGCGGGAG 
ATTTTATCCT ACGTGTCCGT GAGCGCGCAG AGCGGGGTGG TGTTCGCGCA GCGCGCCTTC 
GATCATGAGC AGCTGCGCGC CTTCGAGCTC ACACTGCAGG CCCGCGACCA GGGCTCGCCC 
GCGCTCAGCG CCAACGTGAG CCTGCGCGTG TTAGTGGGCG ACCTCAATGA CAATGCGCCA 
CGGGTGCTGT ACCCCGCGCT GGGGCCTGAT GGCTCCGCCC TCTTCGATAT GGTGCCACGC 
GCCGCAGAGC CCGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGCAGA CTCAGGACAC 
AACGCTTGGC TGTCCTACCA CGTGCTGCAG GCCAGCGAGC CCGGGCTCTT CAGCCTGGGG 
TTGCGCACGG GTGAGGTGCG CACAGCGCGT GCCTTGGGCG ACAGGGACGC GGCCCGCCAG 
CGCCTGCTGG TCGCTGTGCG TGATGGAGGA CAGCCGCCAC TCTCCGCTAC GGCCACGCTG 
CACCTAATCT TCGCGGATAG CCTGCAAGAG GTATTGCCAG ACCTCAGCGA CCGCCGGGAG 
CCCTCTGACC CCCAGGCAAA ACTGCAGTTT TACCTGGTTG TGGCCTTGGC CTTGATCTCA 
GTGCTCTTCT TCCTCGCGGT GATTCTGGCA ATCTCCCTGC GCCTGCGACT CTCTTCCAGG 
TCAGATGCTT GGGACTGTTT TCAGCCTGGT CTCAGCTCCA AGCCTGGACC TGGGGTTCTC 
CCCAATTACA GTGAGGGTAC ATTGCCCTAT TCCTACAACC TGTGTGTTGC CTCACAATCA 
GCCAAGACAG AGTTCAATTT TCTGAACATA ACCCCGGAAT TGGTTCCCGC GCAAGATCTC 
GTCTGTGACA ATGCCTCTTG GGAACAAAAT ACAAATCATG GAGCCGCTGG GGTCCCTTTT 
GCCTCAGATA CTATTTTGAA GCAAGCCCCG CCCAACACGG ACTGGCGTTT CTCTCAGGCC 
CAGAGACCCG GCACCAGCGG CTCCCAAAAT GGCGATGACA CCGGCACCTG GCCCAACAAC 
CAGTTTGACA CAGAGATGCT GCAAGCCATG ATCTTGGCGT CCGCCAGTGA AGCTGCTGAT 
GGGAGCTCCA CCCTGGGAGG GGGTGCCGGC ACCATGGGAT TGAGCGCCCG CTACGGACCC 
CAGTTCACCC TGCAGCACGT GCCCGACTAC CGCCAGAATG TCTACATCCC AGGCAGCAAT 
GCCACACTGA CCAACGCAGC TGGCAAGCGG GATGGCAAGG CCCCAGCAGG TGGCAATGGC 
AACAAGAAGA AGTCGGGCAA GAAGGAGAAG AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDHGB2 ( NM_032096.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_115267.1 Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29795
Clone ID Related Accession (Same CDS sequence)	NM_032096.1
Accession Version	NM_032096.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	protocadherin gamma-B2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF152518.1. Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes the shorter isoform (2). ##Evidence-Data-START## Transcript is intronless :: AF152518.1, BC101805.1 [ECO:0000345] ##Evidence-Data-END##

ATGAAAGCGA GCTCAGGGAG GTGCGGGCTG GTGCGGTGGC TGCAGGTACT GTTGCCCTTC 
CTGTTGTCTT TGTTCCCCGG GGCTCTCCCA GTCCAGATCC GCTATTCAAT TCCAGAGGAG 
CTGGCCAAAA ACTCGGTCGT AGGAAACCTC GCCAAGGATC TGGGGCTCAG CGTCCGGGAC 
TTGCCAGCCC GGAAGCTGCG GGTTAGCGCG GAGAAGGAAT ATTTCACAGT AAACCCAGAA 
AGCGGAGACT TACTTGTGAG TGACAGAATA GACCGAGAAC AGATATGCGG GAAGCAGCCT 
CTGTGTGTTC TGGATTTCGA TACTGTCGCT GAAAATCCAC TAAATATTTT CTACATAGCA 
GTAATTGTGC AGGATATAAA TGATAATACC CCGCTATTCA AACAGACTAA GATTAATTTA 
AAAATTGGCG AATCCACTAA GCCAGGTACA ACATTTCCAC TTGACCCAGC CCTGGATTCA 
GATGTTGGTC CTAACTCACT ACAAAGATAC CACCTTAATG ACAACGAGTA CTTTGATCTC 
GCTGAGAAAC AGACTCCAGA TGGTCGTAAA TATCCTGAGT TGATTCTAAA ACACTCTCTG 
GACAGAGAAG AGCACAGTTT ACATCAATTG GTCCTCACAG CTGTGGATGG CGGAGACCCA 
CCTCAAAGTG GCACGACCCA AATCCGAATC AAAGTCACGG ATGCCAACGA TAACCCTCCA 
GTGTTCAGCC AGGACGTGTA CAGGGTCACC CTGAGGGAGG ACGTGCCGCC GGGCTTCTTT 
GTGCTTCAAG TGACAGCCAC CGACCGGGAT GAAGGCATAA ACGCAGAGAT CACCTACTCC 
TTTCATAATG TGGACGAACA AGTGAAACAC TTTTTCAACT TAAATGAAAA AACAGGAGAA 
ATCACGACAA AGGATGATTT GGATTTTGAG ATTGCAAGTA GTTACACTCT GAGTATCGAA 
GCAAAAGATC CTGGAGATCT AGCAGCCCAC TGCAGTATCC AAGTTGAAAT TCTTGATGAC 
AACGATTGTG CACCTGAAGT TATTGTGACT TCAGTATCTA CTCCCCTACC GGAGGATTCG 
CCACCAGGAA CAGTGATCGC CTTGATAAAA ACGAGAGACA GAGACTCTGG AGAAAATGGA 
GAAGTTTACT GCCAAGTGTT GGGAAATGCC AAGTTTATTT TGAAATCTTC CTCAAAGAAC 
TATTACAAAC TAGTGACAGA CGGCGCTCTG GACCGGGAGG AGATCCCAGA ATACAATCTC 
ACCATCACAG CCACCGACGG GGGCAAGCCG CCCCTCTCCT CCAGCATAAT TGTCACCCTG 
CACATCTCCG ACGTCAACGA TAATGCCCCA GTTTTCCAAC AGACTTCCTA CATGGTTCAC 
GTGGCAGAGA ACAATCCTCC TGGCGCCTCT ATCGCTCAAA TCAGTGCCTC TGACCCTGAC 
TTGGGCCCCA GTGGCCAAGT TTCCTACTCC ATCGTAGCGA GCGACCTGAA GCCGCGGGAG 
ATTTTATCCT ACGTGTCCGT GAGCGCGCAG AGCGGGGTGG TGTTCGCGCA GCGCGCCTTC 
GATCATGAGC AGCTGCGCGC CTTCGAGCTC ACACTGCAGG CCCGCGACCA GGGCTCGCCC 
GCGCTCAGCG CCAACGTGAG CCTGCGCGTG TTAGTGGGCG ACCTCAATGA CAATGCGCCA 
CGGGTGCTGT ACCCCGCGCT GGGGCCTGAT GGCTCCGCCC TCTTCGATAT GGTGCCACGC 
GCCGCAGAGC CCGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGCAGA CTCAGGACAC 
AACGCTTGGC TGTCCTACCA CGTGCTGCAG GCCAGCGAGC CCGGGCTCTT CAGCCTGGGG 
TTGCGCACGG GTGAGGTGCG CACAGCGCGT GCCTTGGGCG ACAGGGACGC GGCCCGCCAG 
CGCCTGCTGG TCGCTGTGCG TGATGGAGGA CAGCCGCCAC TCTCCGCTAC GGCCACGCTG 
CACCTAATCT TCGCGGATAG CCTGCAAGAG GTATTGCCAG ACCTCAGCGA CCGCCGGGAG 
CCCTCTGACC CCCAGGCAAA ACTGCAGTTT TACCTGGTTG TGGCCTTGGC CTTGATCTCA 
GTGCTCTTCT TCCTCGCGGT GATTCTGGCA ATCTCCCTGC GCCTGCGACT CTCTTCCAGG 
TCAGATGCTT GGGACTGTTT TCAGCCTGGT CTCAGCTCCA AGCCTGGACC TGGGGTTCTC 
CCCAATTACA GTGAGGGTAC ATTGCCCTAT TCCTACAACC TGTGTGTTGC CTCACAATCA 
GCCAAGACAG AGTTCAATTT TCTGAACATA ACCCCGGAAT TGGTTCCCGC GCAAGATCTC 
GTCTGTGACA ATGCCTCTTG GGAACAAAAT ACAAATCATG GAGCCGCTGG GGTCCCTTTT 
GCCTCAGATA CTATTTTGAA GGTGAGCTTT AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115267.1
CDS	1..2436
Translation	MKASSGRCGLVRWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLRLRLSSRSDAWDCFQPGLSSKPGPGVLPNYSEGTLPYSYNLCVASQSAKTEFNFLNITPELVPAQDLVCDNASWEQNTNHGAAGVPFASDTILKVSFN

Target ORF information:

RefSeq Version	NM_032096.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin gamma subfamily B, 2 (PCDHGB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032096.1

ORF Insert Sequence:

ATGAAAGCGA GCTCAGGGAG GTGCGGGCTG GTGCGGTGGC TGCAGGTACT GTTGCCCTTC 
CTGTTGTCTT TGTTCCCCGG GGCTCTCCCA GTCCAGATCC GCTATTCAAT TCCAGAGGAG 
CTGGCCAAAA ACTCGGTCGT AGGAAACCTC GCCAAGGATC TGGGGCTCAG CGTCCGGGAC 
TTGCCAGCCC GGAAGCTGCG GGTTAGCGCG GAGAAGGAAT ATTTCACAGT AAACCCAGAA 
AGCGGAGACT TACTTGTGAG TGACAGAATA GACCGAGAAC AGATATGCGG GAAGCAGCCT 
CTGTGTGTTC TGGATTTCGA TACTGTCGCT GAAAATCCAC TAAATATTTT CTACATAGCA 
GTAATTGTGC AGGATATAAA TGATAATACC CCGCTATTCA AACAGACTAA GATTAATTTA 
AAAATTGGCG AATCCACTAA GCCAGGTACA ACATTTCCAC TTGACCCAGC CCTGGATTCA 
GATGTTGGTC CTAACTCACT ACAAAGATAC CACCTTAATG ACAACGAGTA CTTTGATCTC 
GCTGAGAAAC AGACTCCAGA TGGTCGTAAA TATCCTGAGT TGATTCTAAA ACACTCTCTG 
GACAGAGAAG AGCACAGTTT ACATCAATTG GTCCTCACAG CTGTGGATGG CGGAGACCCA 
CCTCAAAGTG GCACGACCCA AATCCGAATC AAAGTCACGG ATGCCAACGA TAACCCTCCA 
GTGTTCAGCC AGGACGTGTA CAGGGTCACC CTGAGGGAGG ACGTGCCGCC GGGCTTCTTT 
GTGCTTCAAG TGACAGCCAC CGACCGGGAT GAAGGCATAA ACGCAGAGAT CACCTACTCC 
TTTCATAATG TGGACGAACA AGTGAAACAC TTTTTCAACT TAAATGAAAA AACAGGAGAA 
ATCACGACAA AGGATGATTT GGATTTTGAG ATTGCAAGTA GTTACACTCT GAGTATCGAA 
GCAAAAGATC CTGGAGATCT AGCAGCCCAC TGCAGTATCC AAGTTGAAAT TCTTGATGAC 
AACGATTGTG CACCTGAAGT TATTGTGACT TCAGTATCTA CTCCCCTACC GGAGGATTCG 
CCACCAGGAA CAGTGATCGC CTTGATAAAA ACGAGAGACA GAGACTCTGG AGAAAATGGA 
GAAGTTTACT GCCAAGTGTT GGGAAATGCC AAGTTTATTT TGAAATCTTC CTCAAAGAAC 
TATTACAAAC TAGTGACAGA CGGCGCTCTG GACCGGGAGG AGATCCCAGA ATACAATCTC 
ACCATCACAG CCACCGACGG GGGCAAGCCG CCCCTCTCCT CCAGCATAAT TGTCACCCTG 
CACATCTCCG ACGTCAACGA TAATGCCCCA GTTTTCCAAC AGACTTCCTA CATGGTTCAC 
GTGGCAGAGA ACAATCCTCC TGGCGCCTCT ATCGCTCAAA TCAGTGCCTC TGACCCTGAC 
TTGGGCCCCA GTGGCCAAGT TTCCTACTCC ATCGTAGCGA GCGACCTGAA GCCGCGGGAG 
ATTTTATCCT ACGTGTCCGT GAGCGCGCAG AGCGGGGTGG TGTTCGCGCA GCGCGCCTTC 
GATCATGAGC AGCTGCGCGC CTTCGAGCTC ACACTGCAGG CCCGCGACCA GGGCTCGCCC 
GCGCTCAGCG CCAACGTGAG CCTGCGCGTG TTAGTGGGCG ACCTCAATGA CAATGCGCCA 
CGGGTGCTGT ACCCCGCGCT GGGGCCTGAT GGCTCCGCCC TCTTCGATAT GGTGCCACGC 
GCCGCAGAGC CCGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGCAGA CTCAGGACAC 
AACGCTTGGC TGTCCTACCA CGTGCTGCAG GCCAGCGAGC CCGGGCTCTT CAGCCTGGGG 
TTGCGCACGG GTGAGGTGCG CACAGCGCGT GCCTTGGGCG ACAGGGACGC GGCCCGCCAG 
CGCCTGCTGG TCGCTGTGCG TGATGGAGGA CAGCCGCCAC TCTCCGCTAC GGCCACGCTG 
CACCTAATCT TCGCGGATAG CCTGCAAGAG GTATTGCCAG ACCTCAGCGA CCGCCGGGAG 
CCCTCTGACC CCCAGGCAAA ACTGCAGTTT TACCTGGTTG TGGCCTTGGC CTTGATCTCA 
GTGCTCTTCT TCCTCGCGGT GATTCTGGCA ATCTCCCTGC GCCTGCGACT CTCTTCCAGG 
TCAGATGCTT GGGACTGTTT TCAGCCTGGT CTCAGCTCCA AGCCTGGACC TGGGGTTCTC 
CCCAATTACA GTGAGGGTAC ATTGCCCTAT TCCTACAACC TGTGTGTTGC CTCACAATCA 
GCCAAGACAG AGTTCAATTT TCTGAACATA ACCCCGGAAT TGGTTCCCGC GCAAGATCTC 
GTCTGTGACA ATGCCTCTTG GGAACAAAAT ACAAATCATG GAGCCGCTGG GGTCCCTTTT 
GCCTCAGATA CTATTTTGAA GGTGAGCTTT AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Genome research11(3)389-404(2001 Mar)
Wu Q,Zhang T,Cheng JF,Kim Y,Grimwood J,Schmutz J,Dickson M,Noonan JP,Zhang MQ,Myers RM,Maniatis T

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Journal of molecular biology299(3)551-72(2000 Jun)
Nollet F,Kools P,van Roy F

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.
Genes & development14(10)1169-80(2000 May)
Yagi T,Takeichi M

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.
Proceedings of the National Academy of Sciences of the United States of America97(7)3124-9(2000 Mar)
Wu Q,Maniatis T

A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Cell97(6)779-90(1999 Jun)
Wu Q,Maniatis T