WDR5B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WDR5B
Entrez Gene ID	54554
Full Name	WD repeat domain 5B
General protein information	Preferred Names WD repeat domain 5B Names WD repeat-containing protein 5B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q21.1
Summary	This intronless gene encodes a protein containing several WD40 repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, including a trp-asp at the C-terminal end. The encoded protein may mediate protein-protein interactions. [provided by RefSeq, Jul 2008]. COMPLETENESS: complete on the 3' end.

mRNA and Protein(s)

mRNA	Protein	Name
NM_019069.3	NP_061942.2	WD repeat-containing protein 5B
NM_019069.4	NP_061942.2	WD repeat-containing protein 5B

Pathways from BioSystems

Homologies

Homo sapiens (human)	WDR5B	NP_061942.2
	WDR5B	XP_001112263.1
Oryza sativa (rice)	Os07g0572000	NP_001060055.1
Bos taurus (cattle)	WDR5B	XP_005201491.1
Rattus norvegicus (Norway rat)	Wdr5b	NP_001019937.1
Arabidopsis thaliana (thale cress)	AT4G02730	NP_192182.1
Canis lupus familiaris (dog)	WDR5B	XP_005639615.1
Mus musculus (house mouse)	Wdr5b	NP_081389.1
Pan troglodytes (chimpanzee)	WDR5B	XP_516691.2

Gene Ontology
Bibliography

Related articles in PubMed

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
O'Seaghdha CM, Yang Q, Glazer NL, Leak TS, Dehghan A, Smith AV, Kao WH, Lohman K, Hwang SJ, Johnson AD, Hofman A, Uitterlinden AG, Chen YD, , Brown EM, Siscovick DS, Harris TB, Psaty BM, Coresh J, Gudnason V, Witteman JC, Liu YM, Kestenbaum BR, Fox CS, K?ttgen A
Human molecular genetics19(21)4296-303(2010 Nov)

Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes.
Gilley J, Fried M
Human molecular genetics8(7)1313-20(1999 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following WDR5B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDR5B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29471	NM_019069.4 Latest version!	Homo sapiens WD repeat domain 5B (WDR5B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu29471	NM_019069.3	Homo sapiens WD repeat domain 5B (WDR5B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WDR5B ( NM_019069.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061942.2 Homo sapiens WD repeat domain 5B (WDR5B), mRNA.

Price & Availability↑

CloneID	OHu29471
Clone ID Related Accession (Same CDS sequence)	NM_019069.3 , NM_019069.4
Accession Version	NM_019069.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 5B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC025762.1, BC043494.1, AA310178.1, AA587370.1 and BU678251.1. On Feb 13, 2004 this sequence version replaced NM_019069.2. COMPLETENESS: complete on the 3' end.

ATGGCAACCA AGGAGTCAAG AGACGCCAAA GCACAGTTGG CCCTCTCCTC ATCGGCCAAT 
CAGAGCAAGG AAGTGCCTGA AAACCCAAAC TATGCTCTCA AATGTACTCT TGTGGGACAC 
ACGGAAGCAG TGTCATCAGT TAAGTTTAGT CCTAATGGAG AATGGCTAGC AAGTTCTTCT 
GCTGATAGGC TAATCATAAT TTGGGGAGCA TATGATGGAA AATATGAGAA AACACTCTAT 
GGTCATAATT TGGAAATATC GGATGTTGCC TGGTCATCAG ATTCCAGTCG TCTTGTTTCT 
GCCTCAGATG ATAAAACTCT AAAATTATGG GATGTGAGAT CTGGAAAATG TTTGAAAACA 
CTGAAGGGGC ACAGTAATTA TGTCTTTTGT TGTAACTTCA ATCCGCCATC CAACCTTATA 
ATCTCGGGAT CTTTTGATGA GACTGTAAAA ATATGGGAGG TGAAAACAGG AAAGTGTCTC 
AAGACTTTGT CTGCTCATTC TGACCCAGTT TCTGCTGTTC ATTTTAATTG TAGTGGGTCC 
TTGATAGTGT CAGGTAGCTA TGATGGCCTC TGTAGAATCT GGGATGCTGC ATCAGGTCAG 
TGTTTAAAAA CGCTCGTTGA TGACGATAAC CCTCCTGTCT CTTTTGTAAA ATTTTCTCCA 
AATGGTAAAT ACATTCTCAC TGCAACTTTG GACAACACTC TTAAACTATG GGATTATAGC 
AGAGGCAGGT GCCTGAAAAC ATACACTGGT CATAAGAATG AGAAATATTG CATATTTGCC 
AATTTTTCAG TTACTGGTGG AAAGTGGATT GTGTCTGGTT CCGAGGATAA CCTGGTTTAC 
ATTTGGAACC TTCAGACTAA AGAGATTGTG CAGAAATTAC AAGGCCATAC AGATGTTGTG 
ATCTCAGCAG CTTGTCATCC TACAGAAAAC CTCATCGCAT CAGCAGCATT AGAAAATGAC 
AAAACAATTA AACTGTGGAT GAGTAACCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061942.2
CDS	508..1500
Translation	MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSNH

Target ORF information:

RefSeq Version	NM_019069.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 5B (WDR5B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019069.3

ORF Insert Sequence:

ATGGCAACCA AGGAGTCAAG AGACGCCAAA GCACAGTTGG CCCTCTCCTC ATCGGCCAAT 
CAGAGCAAGG AAGTGCCTGA AAACCCAAAC TATGCTCTCA AATGTACTCT TGTGGGACAC 
ACGGAAGCAG TGTCATCAGT TAAGTTTAGT CCTAATGGAG AATGGCTAGC AAGTTCTTCT 
GCTGATAGGC TAATCATAAT TTGGGGAGCA TATGATGGAA AATATGAGAA AACACTCTAT 
GGTCATAATT TGGAAATATC GGATGTTGCC TGGTCATCAG ATTCCAGTCG TCTTGTTTCT 
GCCTCAGATG ATAAAACTCT AAAATTATGG GATGTGAGAT CTGGAAAATG TTTGAAAACA 
CTGAAGGGGC ACAGTAATTA TGTCTTTTGT TGTAACTTCA ATCCGCCATC CAACCTTATA 
ATCTCGGGAT CTTTTGATGA GACTGTAAAA ATATGGGAGG TGAAAACAGG AAAGTGTCTC 
AAGACTTTGT CTGCTCATTC TGACCCAGTT TCTGCTGTTC ATTTTAATTG TAGTGGGTCC 
TTGATAGTGT CAGGTAGCTA TGATGGCCTC TGTAGAATCT GGGATGCTGC ATCAGGTCAG 
TGTTTAAAAA CGCTCGTTGA TGACGATAAC CCTCCTGTCT CTTTTGTAAA ATTTTCTCCA 
AATGGTAAAT ACATTCTCAC TGCAACTTTG GACAACACTC TTAAACTATG GGATTATAGC 
AGAGGCAGGT GCCTGAAAAC ATACACTGGT CATAAGAATG AGAAATATTG CATATTTGCC 
AATTTTTCAG TTACTGGTGG AAAGTGGATT GTGTCTGGTT CCGAGGATAA CCTGGTTTAC 
ATTTGGAACC TTCAGACTAA AGAGATTGTG CAGAAATTAC AAGGCCATAC AGATGTTGTG 
ATCTCAGCAG CTTGTCATCC TACAGAAAAC CTCATCGCAT CAGCAGCATT AGAAAATGAC 
AAAACAATTA AACTGTGGAT GAGTAACCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR5B ( NM_019069.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061942.2 Homo sapiens WD repeat domain 5B (WDR5B), mRNA.

Price & Availability↑

CloneID	OHu29471
Clone ID Related Accession (Same CDS sequence)	NM_019069.3 , NM_019069.4
Accession Version	NM_019069.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 5B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083798.14, BC025762.1, BC043494.1, AA310178.1, AA587370.1 and BU678251.1. On May 17, 2019 this sequence version replaced NM_019069.3. ##Evidence-Data-START## Transcript is intronless :: SRR1803612.13213.1, SRR1803616.36101.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000330689.6/ ENSP00000330381.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCAACCA AGGAGTCAAG AGACGCCAAA GCACAGTTGG CCCTCTCCTC ATCGGCCAAT 
CAGAGCAAGG AAGTGCCTGA AAACCCAAAC TATGCTCTCA AATGTACTCT TGTGGGACAC 
ACGGAAGCAG TGTCATCAGT TAAGTTTAGT CCTAATGGAG AATGGCTAGC AAGTTCTTCT 
GCTGATAGGC TAATCATAAT TTGGGGAGCA TATGATGGAA AATATGAGAA AACACTCTAT 
GGTCATAATT TGGAAATATC GGATGTTGCC TGGTCATCAG ATTCCAGTCG TCTTGTTTCT 
GCCTCAGATG ATAAAACTCT AAAATTATGG GATGTGAGAT CTGGAAAATG TTTGAAAACA 
CTGAAGGGGC ACAGTAATTA TGTCTTTTGT TGTAACTTCA ATCCGCCATC CAACCTTATA 
ATCTCGGGAT CTTTTGATGA GACTGTAAAA ATATGGGAGG TGAAAACAGG AAAGTGTCTC 
AAGACTTTGT CTGCTCATTC TGACCCAGTT TCTGCTGTTC ATTTTAATTG TAGTGGGTCC 
TTGATAGTGT CAGGTAGCTA TGATGGCCTC TGTAGAATCT GGGATGCTGC ATCAGGTCAG 
TGTTTAAAAA CGCTCGTTGA TGACGATAAC CCTCCTGTCT CTTTTGTAAA ATTTTCTCCA 
AATGGTAAAT ACATTCTCAC TGCAACTTTG GACAACACTC TTAAACTATG GGATTATAGC 
AGAGGCAGGT GCCTGAAAAC ATACACTGGT CATAAGAATG AGAAATATTG CATATTTGCC 
AATTTTTCAG TTACTGGTGG AAAGTGGATT GTGTCTGGTT CCGAGGATAA CCTGGTTTAC 
ATTTGGAACC TTCAGACTAA AGAGATTGTG CAGAAATTAC AAGGCCATAC AGATGTTGTG 
ATCTCAGCAG CTTGTCATCC TACAGAAAAC CTCATCGCAT CAGCAGCATT AGAAAATGAC 
AAAACAATTA AACTGTGGAT GAGTAACCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061942.2
CDS	535..1527
Translation	MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSNH

Target ORF information:

RefSeq Version	NM_019069.4
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 5B (WDR5B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019069.4

ORF Insert Sequence:

ATGGCAACCA AGGAGTCAAG AGACGCCAAA GCACAGTTGG CCCTCTCCTC ATCGGCCAAT 
CAGAGCAAGG AAGTGCCTGA AAACCCAAAC TATGCTCTCA AATGTACTCT TGTGGGACAC 
ACGGAAGCAG TGTCATCAGT TAAGTTTAGT CCTAATGGAG AATGGCTAGC AAGTTCTTCT 
GCTGATAGGC TAATCATAAT TTGGGGAGCA TATGATGGAA AATATGAGAA AACACTCTAT 
GGTCATAATT TGGAAATATC GGATGTTGCC TGGTCATCAG ATTCCAGTCG TCTTGTTTCT 
GCCTCAGATG ATAAAACTCT AAAATTATGG GATGTGAGAT CTGGAAAATG TTTGAAAACA 
CTGAAGGGGC ACAGTAATTA TGTCTTTTGT TGTAACTTCA ATCCGCCATC CAACCTTATA 
ATCTCGGGAT CTTTTGATGA GACTGTAAAA ATATGGGAGG TGAAAACAGG AAAGTGTCTC 
AAGACTTTGT CTGCTCATTC TGACCCAGTT TCTGCTGTTC ATTTTAATTG TAGTGGGTCC 
TTGATAGTGT CAGGTAGCTA TGATGGCCTC TGTAGAATCT GGGATGCTGC ATCAGGTCAG 
TGTTTAAAAA CGCTCGTTGA TGACGATAAC CCTCCTGTCT CTTTTGTAAA ATTTTCTCCA 
AATGGTAAAT ACATTCTCAC TGCAACTTTG GACAACACTC TTAAACTATG GGATTATAGC 
AGAGGCAGGT GCCTGAAAAC ATACACTGGT CATAAGAATG AGAAATATTG CATATTTGCC 
AATTTTTCAG TTACTGGTGG AAAGTGGATT GTGTCTGGTT CCGAGGATAA CCTGGTTTAC 
ATTTGGAACC TTCAGACTAA AGAGATTGTG CAGAAATTAC AAGGCCATAC AGATGTTGTG 
ATCTCAGCAG CTTGTCATCC TACAGAAAAC CTCATCGCAT CAGCAGCATT AGAAAATGAC 
AAAACAATTA AACTGTGGAT GAGTAACCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
Human molecular genetics19(21)4296-303(2010 Nov)
O'Seaghdha CM,Yang Q,Glazer NL,Leak TS,Dehghan A,Smith AV,Kao WH,Lohman K,Hwang SJ,Johnson AD,Hofman A,Uitterlinden AG,Chen YD,,Brown EM,Siscovick DS,Harris TB,Psaty BM,Coresh J,Gudnason V,Witteman JC,Liu YM,Kestenbaum BR,Fox CS,K?ttgen A

Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes.
Human molecular genetics8(7)1313-20(1999 Jul)
Gilley J,Fried M

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WDR5B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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