PLGLB1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLGLB1
Entrez Gene ID	5343
Full Name	plasminogen-like B1
Synonyms	PLGL,PLGP1,PRGB,PRP-B
General protein information	Preferred Names plasminogen-like B1 Names plasminogen-like protein B plasminogen-related protein B type B plasminogen related
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p11.2
Disorder MIM:	173340

mRNA and Protein(s)

mRNA	Protein	Name
NM_001032392.3	NP_001027564.1	plasminogen-like protein B precursor
NM_001032392.2	NP_001027564.1	plasminogen-like protein B precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PLGLB1	NP_001027564.1
Homo sapiens (human)	PLGLB2	NP_002656.1

Gene Ontology
Bibliography

Related articles in PubMed

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis.
Ichinose A
Biochemistry31(12)3113-8(1992 Mar)

Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.
Ichinose A, Espling ES, Takamatsu J, Saito H, Shinmyozu K, Maruyama I, Petersen TE, Davie EW
Proceedings of the National Academy of Sciences of the United States of America88(1)115-9(1991 Jan)

A gene homologous to plasminogen located on human chromosome 2q11-p11.
Frank SL, Klisak I, Sparkes RS, Lusis AJ
Genomics4(3)449-51(1989 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following PLGLB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLGLB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04520	NM_001032392.3 Latest version!	Homo sapiens plasminogen like B1 (PLGLB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu04520	NM_001032392.2	Homo sapiens plasminogen like B1 (PLGLB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLGLB1 ( NM_001032392.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001027564.1 Homo sapiens plasminogen like B1 (PLGLB1), mRNA.

Price & Availability↑

CloneID	OHu04520
Clone ID Related Accession (Same CDS sequence)	NM_001032392.3 , NM_001032392.2
Accession Version	NM_001032392.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 291bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	plasminogen-like protein B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC125232.4 and AC111200.7. On Nov 21, 2019 this sequence version replaced NM_001032392.2. ##Evidence-Data-START## Transcript exon combination :: BC070296.1, BG566981.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCCCTGGATG ACTATGTGAA TACCCAGGGG CCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGGGCAG GAAGCAGAGA AGAATGTGCA GCAAAATGTG AAGAGGACAA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GCAGTTTTAT TTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001027564.1
CDS	175..465
Translation	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGPSLFSVTKKQLGAGSREECAAKCEEDKEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDAVLFEK

Target ORF information:

RefSeq Version	NM_001032392.3
Organism	Homo sapiens(human)
Definition	Homo sapiens plasminogen like B1 (PLGLB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032392.3

ORF Insert Sequence:

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCCCTGGATG ACTATGTGAA TACCCAGGGG CCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGGGCAG GAAGCAGAGA AGAATGTGCA GCAAAATGTG AAGAGGACAA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GCAGTTTTAT TTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLGLB1 ( NM_001032392.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001027564.1 Homo sapiens plasminogen like B1 (PLGLB1), mRNA.

Price & Availability↑

CloneID	OHu04520
Clone ID Related Accession (Same CDS sequence)	NM_001032392.3 , NM_001032392.2
Accession Version	NM_001032392.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 291bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	plasminogen-like protein B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC125232.4, BC070296.1 and AC111200.7. On Jan 20, 2007 this sequence version replaced NM_001032392.1. ##Evidence-Data-START## Transcript exon combination :: BC107767.1, BG566165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590, SAMN04284274 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCCCTGGATG ACTATGTGAA TACCCAGGGG CCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGGGCAG GAAGCAGAGA AGAATGTGCA GCAAAATGTG AAGAGGACAA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GCAGTTTTAT TTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001027564.1
CDS	64..354
Translation	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGPSLFSVTKKQLGAGSREECAAKCEEDKEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDAVLFEK

Target ORF information:

RefSeq Version	NM_001032392.2
Organism	Homo sapiens(human)
Definition	Homo sapiens plasminogen like B1 (PLGLB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032392.2

ORF Insert Sequence:

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCCCTGGATG ACTATGTGAA TACCCAGGGG CCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGGGCAG GAAGCAGAGA AGAATGTGCA GCAAAATGTG AAGAGGACAA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GCAGTTTTAT TTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis.
Biochemistry31(12)3113-8(1992 Mar)
Ichinose A

Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.
Proceedings of the National Academy of Sciences of the United States of America88(1)115-9(1991 Jan)
Ichinose A,Espling ES,Takamatsu J,Saito H,Shinmyozu K,Maruyama I,Petersen TE,Davie EW

A gene homologous to plasminogen located on human chromosome 2q11-p11.
Genomics4(3)449-51(1989 Apr)
Frank SL,Klisak I,Sparkes RS,Lusis AJ