WBP11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WBP11
Entrez Gene ID	51729
Full Name	WW domain binding protein 11
Synonyms	NPWBP,PPP1R165,SIPP1,WBP-11
General protein information	Preferred Names WW domain binding protein 11 Names WW domain-binding protein 11 Npw38-binding protein NpwBP SH3 domain-binding protein SNP70 protein phosphatase 1, regulatory subunit 165 splicing factor that interacts with PQBP-1 and PP1 splicing factor, PQBP1 and PP1 interacting
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p12.3
Summary	This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_016312.2	NP_057396.1	WW domain-binding protein 11
NM_016312.3	NP_057396.1	WW domain-binding protein 11

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	WBP11	XP_853025.1
Rattus norvegicus (Norway rat)	Wbp11	NP_001009661.1
	WBP11	XP_001090179.1
Homo sapiens (human)	WBP11	NP_057396.1
Pan troglodytes (chimpanzee)	WBP11	XP_520761.2
Mus musculus (house mouse)	Wbp11	NP_068360.4
Rattus norvegicus (Norway rat)	LOC100910115	XP_006237641.1

Gene Ontology
Bibliography

Related articles in PubMed

A new role for FBP21 as regulator of Brr2 helicase activity.
Henning LM, Santos KF, Sticht J, Jehle S, Lee CT, Wittwer M, Urlaub H, Stelzl U, Wahl MC, Freund C
Nucleic acids research45(13)7922-7937(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome.
Pucheta-Martinez E, D'Amelio N, Lelli M, Martinez-Torrecuadrada JL, Sudol M, Saladino G, Gervasio FL
Scientific reports630293(2016 Jul)

Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.
Mizuguchi M, Obita T, Kajiyama A, Kozakai Y, Nakai T, Nabeshima Y, Okazawa H
FEBS letters590(14)2221-31(2016 07)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SIPP1 is a positive regulator of pre-mRNA splicing that is regulated by nucleocytoplasmic shuttling
Title: Nucleocytoplasmic shuttling of the splicing factor SIPP1.

The following WBP11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WBP11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28147	NM_016312.3 Latest version!	Homo sapiens WW domain binding protein 11 (WBP11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu28147	NM_016312.2	Homo sapiens WW domain binding protein 11 (WBP11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WBP11 ( NM_016312.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_057396.1 Homo sapiens WW domain binding protein 11 (WBP11), mRNA.

Price & Availability↑

CloneID	OHu28147
Clone ID Related Accession (Same CDS sequence)	NM_016312.2 , NM_016312.3
Accession Version	NM_016312.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	WW domain-binding protein 11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC001621.1. On Jan 25, 2002 this sequence version replaced NM_016312.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001621.1, BC023532.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGACGGA GATCTACATC ATCCACCAAG AGTGGAAAAT TTATGAACCC CACAGACCAA 
GCCCGAAAGG AAGCCCGGAA GAGAGAATTA AAGAAGAACA AAAAACAGCG CATGATGGTT 
CGAGCTGCAG TTTTAAAGAT GAAGGATCCA AAACAGATAA TCCGAGACAT GGAGAAATTG 
GATGAAATGG AGTTTAACCC AGTGCAACAG CCACAATTAA ATGAGAAAGT ACTGAAAGAC 
AAGCGTAAAA AGCTGCGTGA AACCTTTGAA CGTATTCTAC GACTCTATGA AAAAGAGAAT 
CCAGATATTT ACAAAGAATT GAGAAAGCTA GAAGTAGAAT ATGAACAGAA GAGGGCTCAA 
CTTAGCCAAT ATTTTGATGC TGTCAAGAAT GCTCAGCATG TGGAAGTGGA GAGTATTCCT 
TTGCCAGATA TGCCACATGC TCCTTCCAAC ATTTTGATCC AGGACATTCC ACTTCCTGGT 
GCCCAGCCAC CCTCTATCCT AAAGAAAACC TCAGCCTATG GACCTCCAAC TCGGGCAGTT 
TCTATCCTTC CTCTTCTTGG ACATGGTGTT CCACGTTTGC CCCCTGGCAG AAAACCTCCT 
GGCCCTCCCC CTGGTCCACC TCCTCCTCAA GTCGTGCAGA TGTATGGCCG TAAAGTGGGT 
TTTGCCCTAG ATCTTCCCCC TCGTAGGCGA GATGAAGACA TGTTATATAG TCCTGAACTT 
GCCCAGCGAG GTCATGATGA TGATGTTTCT AGCACCAGTG AAGATGATGG CTATCCTGAG 
GACATGGATC AAGATAAGCA TGATGACAGT ACTGATGACA GTGACACCGA CAAATCAGAT 
GGAGAAAGTG ACGGGGATGA ATTTGTGCAC CGTGATAATG GTGAGAGAGA CAACAATGAA 
GAAAAGAAGT CAGGTCTGAG TGTACGGTTT GCAGATATGC CTGGAAAATC AAGGAAGAAA 
AAGAAGAACA TGAAGGAACT GACTCCTCTT CAAGCCATGA TGCTTCGTAT GGCAGGTCAA 
GAAATCCCTG AGGAGGGACG GGAAGTAGAG GAATTTTCAG AGGACGATGA TGAAGATGAT 
TCTGATGACT CTGAAGCAGA AAAGCAATCA CAAAAGCAGC ATAAAGAGGA ATCCCATTCT 
GATGGCACAT CCACTGCTTC TTCACAGCAG CAGGCTCCGC CGCAGTCTGT TCCTCCTTCT 
CAGATACAAG CACCTCCCAT GCCAGGACCA CCACCTCTTG GACCACCACC TGCTCCACCA 
TTACGGCCTC CTGGGCCACC TACAGGCCTT CCTCCTGGTC CACCTCCAGG AGCTCCTCCA 
TTCCTGAGAC CACCTGGAAT GCCAGGACTC CGAGGGCCCT TACCCCGACT TTTACCTCCA 
GGACCACCAC CAGGCCGACC CCCTGGCCCT CCCCCAGGTC CACCTCCAGG TCTGCCTCCT 
GGTCCCCCTC CTCGTGGACC CCCACCAAGG CTACCTCCCC CTGCACCTCC AGGTATTCCT 
CCACCTCGTC CTGGCATGAT GCGCCCACCT TTGGTGCCTC CCCTTGGACC TGCCCCCCCT 
GGGCTGTTCC CACCAGCTCC CTTGCCAAAC CCTGGGGTTT TAAGTGCCCC ACCCAACTTG 
ATTCAGCGAC CCAAGGCGGA TGATACAAGT GCAGCCACCA TTGAGAAGAA AGCCACAGCA 
ACCATCAGTG CCAAGCCACA GATCACTAAT CCCAAGGCAG AGATTACTCG ATTTGTGCCC 
ACTGCACTGA GAGTACGTCG GGAGAATAAA GGGGCTACTG CTGCTCCCCA AAGAAAGTCA 
GAGGATGATT CTGCTGTGCC TCTTGCCAAA GCAGCACCCA AATCTGGTCC TTCTGTTCCT 
GTCTCAGTAC AAACTAAGGA TGATGTCTAT GAGGCTTTCA TGAAAGAGAT GGAAGGGCTA 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057396.1
CDS	162..2087
Translation	MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL

Target ORF information:

RefSeq Version	NM_016312.2
Organism	Homo sapiens(human)
Definition	Homo sapiens WW domain binding protein 11 (WBP11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016312.2

ORF Insert Sequence:

ATGGGACGGA GATCTACATC ATCCACCAAG AGTGGAAAAT TTATGAACCC CACAGACCAA 
GCCCGAAAGG AAGCCCGGAA GAGAGAATTA AAGAAGAACA AAAAACAGCG CATGATGGTT 
CGAGCTGCAG TTTTAAAGAT GAAGGATCCA AAACAGATAA TCCGAGACAT GGAGAAATTG 
GATGAAATGG AGTTTAACCC AGTGCAACAG CCACAATTAA ATGAGAAAGT ACTGAAAGAC 
AAGCGTAAAA AGCTGCGTGA AACCTTTGAA CGTATTCTAC GACTCTATGA AAAAGAGAAT 
CCAGATATTT ACAAAGAATT GAGAAAGCTA GAAGTAGAAT ATGAACAGAA GAGGGCTCAA 
CTTAGCCAAT ATTTTGATGC TGTCAAGAAT GCTCAGCATG TGGAAGTGGA GAGTATTCCT 
TTGCCAGATA TGCCACATGC TCCTTCCAAC ATTTTGATCC AGGACATTCC ACTTCCTGGT 
GCCCAGCCAC CCTCTATCCT AAAGAAAACC TCAGCCTATG GACCTCCAAC TCGGGCAGTT 
TCTATCCTTC CTCTTCTTGG ACATGGTGTT CCACGTTTGC CCCCTGGCAG AAAACCTCCT 
GGCCCTCCCC CTGGTCCACC TCCTCCTCAA GTCGTGCAGA TGTATGGCCG TAAAGTGGGT 
TTTGCCCTAG ATCTTCCCCC TCGTAGGCGA GATGAAGACA TGTTATATAG TCCTGAACTT 
GCCCAGCGAG GTCATGATGA TGATGTTTCT AGCACCAGTG AAGATGATGG CTATCCTGAG 
GACATGGATC AAGATAAGCA TGATGACAGT ACTGATGACA GTGACACCGA CAAATCAGAT 
GGAGAAAGTG ACGGGGATGA ATTTGTGCAC CGTGATAATG GTGAGAGAGA CAACAATGAA 
GAAAAGAAGT CAGGTCTGAG TGTACGGTTT GCAGATATGC CTGGAAAATC AAGGAAGAAA 
AAGAAGAACA TGAAGGAACT GACTCCTCTT CAAGCCATGA TGCTTCGTAT GGCAGGTCAA 
GAAATCCCTG AGGAGGGACG GGAAGTAGAG GAATTTTCAG AGGACGATGA TGAAGATGAT 
TCTGATGACT CTGAAGCAGA AAAGCAATCA CAAAAGCAGC ATAAAGAGGA ATCCCATTCT 
GATGGCACAT CCACTGCTTC TTCACAGCAG CAGGCTCCGC CGCAGTCTGT TCCTCCTTCT 
CAGATACAAG CACCTCCCAT GCCAGGACCA CCACCTCTTG GACCACCACC TGCTCCACCA 
TTACGGCCTC CTGGGCCACC TACAGGCCTT CCTCCTGGTC CACCTCCAGG AGCTCCTCCA 
TTCCTGAGAC CACCTGGAAT GCCAGGACTC CGAGGGCCCT TACCCCGACT TTTACCTCCA 
GGACCACCAC CAGGCCGACC CCCTGGCCCT CCCCCAGGTC CACCTCCAGG TCTGCCTCCT 
GGTCCCCCTC CTCGTGGACC CCCACCAAGG CTACCTCCCC CTGCACCTCC AGGTATTCCT 
CCACCTCGTC CTGGCATGAT GCGCCCACCT TTGGTGCCTC CCCTTGGACC TGCCCCCCCT 
GGGCTGTTCC CACCAGCTCC CTTGCCAAAC CCTGGGGTTT TAAGTGCCCC ACCCAACTTG 
ATTCAGCGAC CCAAGGCGGA TGATACAAGT GCAGCCACCA TTGAGAAGAA AGCCACAGCA 
ACCATCAGTG CCAAGCCACA GATCACTAAT CCCAAGGCAG AGATTACTCG ATTTGTGCCC 
ACTGCACTGA GAGTACGTCG GGAGAATAAA GGGGCTACTG CTGCTCCCCA AAGAAAGTCA 
GAGGATGATT CTGCTGTGCC TCTTGCCAAA GCAGCACCCA AATCTGGTCC TTCTGTTCCT 
GTCTCAGTAC AAACTAAGGA TGATGTCTAT GAGGCTTTCA TGAAAGAGAT GGAAGGGCTA 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WBP11 ( NM_016312.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057396.1 Homo sapiens WW domain binding protein 11 (WBP11), mRNA.

Price & Availability↑

CloneID	OHu28147
Clone ID Related Accession (Same CDS sequence)	NM_016312.2 , NM_016312.3
Accession Version	NM_016312.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	WW domain-binding protein 11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007655.1 and AC010168.6. On Nov 25, 2018 this sequence version replaced NM_016312.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.155094.1, SRR1803616.79110.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261167.7/ ENSP00000261167.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGACGGA GATCTACATC ATCCACCAAG AGTGGAAAAT TTATGAACCC CACAGACCAA 
GCCCGAAAGG AAGCCCGGAA GAGAGAATTA AAGAAGAACA AAAAACAGCG CATGATGGTT 
CGAGCTGCAG TTTTAAAGAT GAAGGATCCA AAACAGATAA TCCGAGACAT GGAGAAATTG 
GATGAAATGG AGTTTAACCC AGTGCAACAG CCACAATTAA ATGAGAAAGT ACTGAAAGAC 
AAGCGTAAAA AGCTGCGTGA AACCTTTGAA CGTATTCTAC GACTCTATGA AAAAGAGAAT 
CCAGATATTT ACAAAGAATT GAGAAAGCTA GAAGTAGAAT ATGAACAGAA GAGGGCTCAA 
CTTAGCCAAT ATTTTGATGC TGTCAAGAAT GCTCAGCATG TGGAAGTGGA GAGTATTCCT 
TTGCCAGATA TGCCACATGC TCCTTCCAAC ATTTTGATCC AGGACATTCC ACTTCCTGGT 
GCCCAGCCAC CCTCTATCCT AAAGAAAACC TCAGCCTATG GACCTCCAAC TCGGGCAGTT 
TCTATCCTTC CTCTTCTTGG ACATGGTGTT CCACGTTTGC CCCCTGGCAG AAAACCTCCT 
GGCCCTCCCC CTGGTCCACC TCCTCCTCAA GTCGTGCAGA TGTATGGCCG TAAAGTGGGT 
TTTGCCCTAG ATCTTCCCCC TCGTAGGCGA GATGAAGACA TGTTATATAG TCCTGAACTT 
GCCCAGCGAG GTCATGATGA TGATGTTTCT AGCACCAGTG AAGATGATGG CTATCCTGAG 
GACATGGATC AAGATAAGCA TGATGACAGT ACTGATGACA GTGACACCGA CAAATCAGAT 
GGAGAAAGTG ACGGGGATGA ATTTGTGCAC CGTGATAATG GTGAGAGAGA CAACAATGAA 
GAAAAGAAGT CAGGTCTGAG TGTACGGTTT GCAGATATGC CTGGAAAATC AAGGAAGAAA 
AAGAAGAACA TGAAGGAACT GACTCCTCTT CAAGCCATGA TGCTTCGTAT GGCAGGTCAA 
GAAATCCCTG AGGAGGGACG GGAAGTAGAG GAATTTTCAG AGGACGATGA TGAAGATGAT 
TCTGATGACT CTGAAGCAGA AAAGCAATCA CAAAAGCAGC ATAAAGAGGA ATCCCATTCT 
GATGGCACAT CCACTGCTTC TTCACAGCAG CAGGCTCCGC CGCAGTCTGT TCCTCCTTCT 
CAGATACAAG CACCTCCCAT GCCAGGACCA CCACCTCTTG GACCACCACC TGCTCCACCA 
TTACGGCCTC CTGGGCCACC TACAGGCCTT CCTCCTGGTC CACCTCCAGG AGCTCCTCCA 
TTCCTGAGAC CACCTGGAAT GCCAGGACTC CGAGGGCCCT TACCCCGACT TTTACCTCCA 
GGACCACCAC CAGGCCGACC CCCTGGCCCT CCCCCAGGTC CACCTCCAGG TCTGCCTCCT 
GGTCCCCCTC CTCGTGGACC CCCACCAAGG CTACCTCCCC CTGCACCTCC AGGTATTCCT 
CCACCTCGTC CTGGCATGAT GCGCCCACCT TTGGTGCCTC CCCTTGGACC TGCCCCCCCT 
GGGCTGTTCC CACCAGCTCC CTTGCCAAAC CCTGGGGTTT TAAGTGCCCC ACCCAACTTG 
ATTCAGCGAC CCAAGGCGGA TGATACAAGT GCAGCCACCA TTGAGAAGAA AGCCACAGCA 
ACCATCAGTG CCAAGCCACA GATCACTAAT CCCAAGGCAG AGATTACTCG ATTTGTGCCC 
ACTGCACTGA GAGTACGTCG GGAGAATAAA GGGGCTACTG CTGCTCCCCA AAGAAAGTCA 
GAGGATGATT CTGCTGTGCC TCTTGCCAAA GCAGCACCCA AATCTGGTCC TTCTGTTCCT 
GTCTCAGTAC AAACTAAGGA TGATGTCTAT GAGGCTTTCA TGAAAGAGAT GGAAGGGCTA 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057396.1
CDS	173..2098
Translation	MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL

Target ORF information:

RefSeq Version	NM_016312.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WW domain binding protein 11 (WBP11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016312.3

ORF Insert Sequence:

ATGGGACGGA GATCTACATC ATCCACCAAG AGTGGAAAAT TTATGAACCC CACAGACCAA 
GCCCGAAAGG AAGCCCGGAA GAGAGAATTA AAGAAGAACA AAAAACAGCG CATGATGGTT 
CGAGCTGCAG TTTTAAAGAT GAAGGATCCA AAACAGATAA TCCGAGACAT GGAGAAATTG 
GATGAAATGG AGTTTAACCC AGTGCAACAG CCACAATTAA ATGAGAAAGT ACTGAAAGAC 
AAGCGTAAAA AGCTGCGTGA AACCTTTGAA CGTATTCTAC GACTCTATGA AAAAGAGAAT 
CCAGATATTT ACAAAGAATT GAGAAAGCTA GAAGTAGAAT ATGAACAGAA GAGGGCTCAA 
CTTAGCCAAT ATTTTGATGC TGTCAAGAAT GCTCAGCATG TGGAAGTGGA GAGTATTCCT 
TTGCCAGATA TGCCACATGC TCCTTCCAAC ATTTTGATCC AGGACATTCC ACTTCCTGGT 
GCCCAGCCAC CCTCTATCCT AAAGAAAACC TCAGCCTATG GACCTCCAAC TCGGGCAGTT 
TCTATCCTTC CTCTTCTTGG ACATGGTGTT CCACGTTTGC CCCCTGGCAG AAAACCTCCT 
GGCCCTCCCC CTGGTCCACC TCCTCCTCAA GTCGTGCAGA TGTATGGCCG TAAAGTGGGT 
TTTGCCCTAG ATCTTCCCCC TCGTAGGCGA GATGAAGACA TGTTATATAG TCCTGAACTT 
GCCCAGCGAG GTCATGATGA TGATGTTTCT AGCACCAGTG AAGATGATGG CTATCCTGAG 
GACATGGATC AAGATAAGCA TGATGACAGT ACTGATGACA GTGACACCGA CAAATCAGAT 
GGAGAAAGTG ACGGGGATGA ATTTGTGCAC CGTGATAATG GTGAGAGAGA CAACAATGAA 
GAAAAGAAGT CAGGTCTGAG TGTACGGTTT GCAGATATGC CTGGAAAATC AAGGAAGAAA 
AAGAAGAACA TGAAGGAACT GACTCCTCTT CAAGCCATGA TGCTTCGTAT GGCAGGTCAA 
GAAATCCCTG AGGAGGGACG GGAAGTAGAG GAATTTTCAG AGGACGATGA TGAAGATGAT 
TCTGATGACT CTGAAGCAGA AAAGCAATCA CAAAAGCAGC ATAAAGAGGA ATCCCATTCT 
GATGGCACAT CCACTGCTTC TTCACAGCAG CAGGCTCCGC CGCAGTCTGT TCCTCCTTCT 
CAGATACAAG CACCTCCCAT GCCAGGACCA CCACCTCTTG GACCACCACC TGCTCCACCA 
TTACGGCCTC CTGGGCCACC TACAGGCCTT CCTCCTGGTC CACCTCCAGG AGCTCCTCCA 
TTCCTGAGAC CACCTGGAAT GCCAGGACTC CGAGGGCCCT TACCCCGACT TTTACCTCCA 
GGACCACCAC CAGGCCGACC CCCTGGCCCT CCCCCAGGTC CACCTCCAGG TCTGCCTCCT 
GGTCCCCCTC CTCGTGGACC CCCACCAAGG CTACCTCCCC CTGCACCTCC AGGTATTCCT 
CCACCTCGTC CTGGCATGAT GCGCCCACCT TTGGTGCCTC CCCTTGGACC TGCCCCCCCT 
GGGCTGTTCC CACCAGCTCC CTTGCCAAAC CCTGGGGTTT TAAGTGCCCC ACCCAACTTG 
ATTCAGCGAC CCAAGGCGGA TGATACAAGT GCAGCCACCA TTGAGAAGAA AGCCACAGCA 
ACCATCAGTG CCAAGCCACA GATCACTAAT CCCAAGGCAG AGATTACTCG ATTTGTGCCC 
ACTGCACTGA GAGTACGTCG GGAGAATAAA GGGGCTACTG CTGCTCCCCA AAGAAAGTCA 
GAGGATGATT CTGCTGTGCC TCTTGCCAAA GCAGCACCCA AATCTGGTCC TTCTGTTCCT 
GTCTCAGTAC AAACTAAGGA TGATGTCTAT GAGGCTTTCA TGAAAGAGAT GGAAGGGCTA 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A new role for FBP21 as regulator of Brr2 helicase activity.
Nucleic acids research45(13)7922-7937(2017 Jul)
Henning LM,Santos KF,Sticht J,Jehle S,Lee CT,Wittwer M,Urlaub H,Stelzl U,Wahl MC,Freund C

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome.
Scientific reports630293(2016 Jul)
Pucheta-Martinez E,D'Amelio N,Lelli M,Martinez-Torrecuadrada JL,Sudol M,Saladino G,Gervasio FL

Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.
FEBS letters590(14)2221-31(2016 07)
Mizuguchi M,Obita T,Kajiyama A,Kozakai Y,Nakai T,Nabeshima Y,Okazawa H

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

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WBP11 cDNA ORF clone, Homo sapiens(human)

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