ANGPTL4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ANGPTL4
Entrez Gene ID	51129
Full Name	angiopoietin like 4
Synonyms	ARP4,FIAF,HARP,HFARP,NL2,PGAR,TGQTL,UNQ171,pp1158
General protein information	Preferred Names angiopoietin like 4 Names angiopoietin-related protein 4 PPARG angiopoietin related protein fasting-induced adipose factor hepatic angiopoietin-related protein hepatic fibrinogen/angiopoietin-related protein peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.2
Summary	This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013].
Disorder MIM:	605910
Disorder Html:	Plasma triglyceride level QTL, low, 615881 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_139314.2	NP_647475.1	angiopoietin-related protein 4 isoform a precursor
NM_001039667.2	NP_001034756.1	angiopoietin-related protein 4 isoform b precursor
XM_005272485.3	XP_005272542.1	angiopoietin-related protein 4 isoform X2
NM_139314.3	NP_647475.1	angiopoietin-related protein 4 isoform a precursor
NM_001039667.3	NP_001034756.1	angiopoietin-related protein 4 isoform b precursor
XM_005272484.3	XP_005272541.1	angiopoietin-related protein 4 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ANGPTL4	NP_647475.1
Pan troglodytes (chimpanzee)	ANGPTL4	XP_001147708.3
Canis lupus familiaris (dog)	ANGPTL4	XP_005633282.1
Danio rerio (zebrafish)	angptl4	NP_001243132.1
Bos taurus (cattle)	ANGPTL4	NP_001039508.1
Gallus gallus (chicken)	ANGPTL4	XP_001232284.2
Xenopus tropicalis (tropical clawed frog)	angptl4	XP_002938598.1
Rattus norvegicus (Norway rat)	Angptl4	NP_954546.1
Mus musculus (house mouse)	Angptl4	NP_065606.2

Gene Ontology
Bibliography

Related articles in PubMed

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover.
Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C
Developmental cell43(1)71-82.e6(2017 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate angiopoietin-like 4 (ANGPTL4) as a key player that coordinates an increase in cellular energy flux crucial for EMT via an ANGPTL4/14-3-3gamma signaling axis.
Title: Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial-mesenchymal transition by inducing 14-3-3? expression.

Serum ANGPTL4 is elevated in coronary artery disease, but levels do not reflect severity of disease.
Title: Do ANGPTL-4 and galectin-3 reflect the severity of coronary artery disease?

identify ANGPTL4 as a Wnt signaling antagonist that binds to syndecans and forms a ternary complex with the Wnt co-receptor Lipoprotein receptor-related protein 6
Title: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover.

Data suggest that purified FLD (C-terminal fibrinogen-like domain) of ANGPTL4 is sufficient to stimulate lipolysis in primary adipocytes; increasing circulating FLD levels in mice not only induces white adipose tissue lipolysis in vivo but also reduces diet-induced obesity without affecting LPL (lipoprotein lipase) activity; increasing systemic FLD levels induces beige conversion in white adipose tissue.
Title: The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure.

results suggest that ANGPTL4 could contribute to the development of retinal neovascularization in sickle cell patients and could therefore be a therapeutic target for the treatment of PSR
Title: Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy.

The following ANGPTL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANGPTL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25209	NM_001039667.3 Latest version!	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu25270	NM_139314.3 Latest version!	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu51631	XM_005272484.3 Latest version!	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu51632	XM_005272485.3 Latest version!	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu25270	NM_139314.2	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu25209	NM_001039667.2	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ANGPTL4 ( NM_001039667.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034756.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu25209
Clone ID Related Accession (Same CDS sequence)	NM_001039667.2 , NM_001039667.3
Accession Version	NM_001039667.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG424907.1, AF202636.1 and BP397348.1. On Sep 13, 2013 this sequence version replaced NM_001039667.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The encoded isoform (b) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.24110.1, SRR3476690.372230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGGAGGC TGGTGGTTTG GCACCTGCAG CCATTCCAAC 
CTCAACGGCC AGTACTTCCG CTCCATCCCA CAGCAGCGGC AGAAGCTTAA GAAGGGAATC 
TTCTGGAAGA CCTGGCGGGG CCGCTACTAC CCGCTGCAGG CCACCACCAT GTTGATCCAG 
CCCATGGCAG CAGAGGCAGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034756.1
CDS	196..1302
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHHGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	NM_001039667.2
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039667.2

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGGAGGC TGGTGGTTTG GCACCTGCAG CCATTCCAAC 
CTCAACGGCC AGTACTTCCG CTCCATCCCA CAGCAGCGGC AGAAGCTTAA GAAGGGAATC 
TTCTGGAAGA CCTGGCGGGG CCGCTACTAC CCGCTGCAGG CCACCACCAT GTTGATCCAG 
CCCATGGCAG CAGAGGCAGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL4 ( NM_001039667.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034756.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu25209
Clone ID Related Accession (Same CDS sequence)	NM_001039667.2 , NM_001039667.3
Accession Version	NM_001039667.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF202636.1 and BP397348.1. On Jun 1, 2019 this sequence version replaced NM_001039667.2. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The encoded isoform (b) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.24110.1, SRR3476690.362879.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGGAGGC TGGTGGTTTG GCACCTGCAG CCATTCCAAC 
CTCAACGGCC AGTACTTCCG CTCCATCCCA CAGCAGCGGC AGAAGCTTAA GAAGGGAATC 
TTCTGGAAGA CCTGGCGGGG CCGCTACTAC CCGCTGCAGG CCACCACCAT GTTGATCCAG 
CCCATGGCAG CAGAGGCAGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034756.1
CDS	168..1274
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHHGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	NM_001039667.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039667.3

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGGAGGC TGGTGGTTTG GCACCTGCAG CCATTCCAAC 
CTCAACGGCC AGTACTTCCG CTCCATCCCA CAGCAGCGGC AGAAGCTTAA GAAGGGAATC 
TTCTGGAAGA CCTGGCGGGG CCGCTACTAC CCGCTGCAGG CCACCACCAT GTTGATCCAG 
CCCATGGCAG CAGAGGCAGC CTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL4 ( NM_139314.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_647475.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25270
Clone ID Related Accession (Same CDS sequence)	NM_139314.2 , NM_139314.3
Accession Version	NM_139314.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG424907.1, AF202636.1 and BP397348.1. This sequence is a reference standard in the RefSeqGene project. On Sep 13, 2013 this sequence version replaced NM_139314.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF202636.1, AB056477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_647475.1
CDS	196..1416
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	NM_139314.2
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139314.2

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL4 ( NM_139314.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_647475.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.

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CloneID	OHu25270
Clone ID Related Accession (Same CDS sequence)	NM_139314.2 , NM_139314.3
Accession Version	NM_139314.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF202636.1 and BP397348.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_139314.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.23439.1, SRR3476690.114673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301455.7/ ENSP00000301455.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_647475.1
CDS	168..1388
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	NM_139314.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139314.3

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL4 ( XM_005272484.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005272541.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X1, mRNA.

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CloneID	OHu51631
Clone ID Related Accession (Same CDS sequence)	XM_005272484.3
Accession Version	XM_005272484.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1275bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005272484.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGC CCCATCGGTG GCTCAAAGAC CTGACCATGT TCCCTCTCCC 
CTGACCCCGG CAGGAGGCTG GTGGTTTGGC ACCTGCAGCC ATTCCAACCT CAACGGCCAG 
TACTTCCGCT CCATCCCACA GCAGCGGCAG AAGCTTAAGA AGGGAATCTT CTGGAAGACC 
TGGCGGGGCC GCTACTACCC GCTGCAGGCC ACCACCATGT TGATCCAGCC CATGGCAGCA 
GAGGCAGCCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005272541.1
CDS	194..1468
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSAPSVAQRPDHVPSPLTPAGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	XM_005272484.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005272484.3

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCGGC TGCCCAGGGA TTGCCAGGAG CTGTTCCAGG TTGGGGAGAG GCAGAGTGGA 
CTATTTGAAA TCCAGCCTCA GGGGTCTCCG CCATTTTTGG TGAACTGCAA GATGACCTCA 
GATGGAGGCT GGACAGTAAT TCAGAGGCGC CACGATGGCT CAGTGGACTT CAACCGGCCC 
TGGGAAGCCT ACAAGGCGGG GTTTGGGGAT CCCCACGGCG AGTTCTGGCT GGGTCTGGAG 
AAGGTGCATA GCATCACGGG GGACCGCAAC AGCCGCCTGG CCGTGCAGCT GCGGGACTGG 
GATGGCAACG CCGAGTTGCT GCAGTTCTCC GTGCACCTGG GTGGCGAGGA CACGGCCTAT 
AGCCTGCAGC TCACTGCACC CGTGGCCGGC CAGCTGGGCG CCACCACCGT CCCACCCAGC 
GGCCTCTCCG TACCCTTCTC CACTTGGGAC CAGGATCACG ACCTCCGCAG GGACAAGAAC 
TGCGCCAAGA GCCTCTCTGC CCCATCGGTG GCTCAAAGAC CTGACCATGT TCCCTCTCCC 
CTGACCCCGG CAGGAGGCTG GTGGTTTGGC ACCTGCAGCC ATTCCAACCT CAACGGCCAG 
TACTTCCGCT CCATCCCACA GCAGCGGCAG AAGCTTAAGA AGGGAATCTT CTGGAAGACC 
TGGCGGGGCC GCTACTACCC GCTGCAGGCC ACCACCATGT TGATCCAGCC CATGGCAGCA 
GAGGCAGCCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL4 ( XM_005272485.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005272542.1 Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu51632
Clone ID Related Accession (Same CDS sequence)	XM_005272485.3
Accession Version	XM_005272485.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005272485.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGCCCCA TCGGTGGCTC AAAGACCTGA CCATGTTCCC 
TCTCCCCTGA CCCCGGCAGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005272542.1
CDS	194..1354
Translation	MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHHGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSAPSVAQRPDHVPSPLTPAGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS

Target ORF information:

RefSeq Version	XM_005272485.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 4 (ANGPTL4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005272485.3

ORF Insert Sequence:

ATGAGCGGTG CTCCGACGGC CGGGGCAGCC CTGATGCTCT GCGCCGCCAC CGCCGTGCTA 
CTGAGCGCTC AGGGCGGACC CGTGCAGTCC AAGTCGCCGC GCTTTGCGTC CTGGGACGAG 
ATGAATGTCC TGGCGCACGG ACTCCTGCAG CTCGGCCAGG GGCTGCGCGA ACACGCGGAG 
CGCACCCGCA GTCAGCTGAG CGCGCTGGAG CGGCGCCTGA GCGCGTGCGG GTCCGCCTGT 
CAGGGAACCG AGGGGTCCAC CGACCTCCCG TTAGCCCCTG AGAGCCGGGT GGACCCTGAG 
GTCCTTCACA GCCTGCAGAC ACAACTCAAG GCTCAGAACA GCAGGATCCA GCAACTCTTC 
CACAAGGTGG CCCAGCAGCA GCGGCACCTG GAGAAGCAGC ACCTGCGAAT TCAGCATCTG 
CAAAGCCAGT TTGGCCTCCT GGACCACAAG CACCTAGACC ATGAGGTGGC CAAGCCTGCC 
CGAAGAAAGA GGCTGCCCGA GATGGCCCAG CCAGTTGACC CGGCTCACAA TGTCAGCCGC 
CTGCACCATG GAGGCTGGAC AGTAATTCAG AGGCGCCACG ATGGCTCAGT GGACTTCAAC 
CGGCCCTGGG AAGCCTACAA GGCGGGGTTT GGGGATCCCC ACGGCGAGTT CTGGCTGGGT 
CTGGAGAAGG TGCATAGCAT CACGGGGGAC CGCAACAGCC GCCTGGCCGT GCAGCTGCGG 
GACTGGGATG GCAACGCCGA GTTGCTGCAG TTCTCCGTGC ACCTGGGTGG CGAGGACACG 
GCCTATAGCC TGCAGCTCAC TGCACCCGTG GCCGGCCAGC TGGGCGCCAC CACCGTCCCA 
CCCAGCGGCC TCTCCGTACC CTTCTCCACT TGGGACCAGG ATCACGACCT CCGCAGGGAC 
AAGAACTGCG CCAAGAGCCT CTCTGCCCCA TCGGTGGCTC AAAGACCTGA CCATGTTCCC 
TCTCCCCTGA CCCCGGCAGG AGGCTGGTGG TTTGGCACCT GCAGCCATTC CAACCTCAAC 
GGCCAGTACT TCCGCTCCAT CCCACAGCAG CGGCAGAAGC TTAAGAAGGG AATCTTCTGG 
AAGACCTGGC GGGGCCGCTA CTACCCGCTG CAGGCCACCA CCATGTTGAT CCAGCCCATG 
GCAGCAGAGG CAGCCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover.
Developmental cell43(1)71-82.e6(2017 10)
Kirsch N,Chang LS,Koch S,Glinka A,Dolde C,Colozza G,Benitez MDJ,De Robertis EM,Niehrs C

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ANGPTL4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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