PCDH8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCDH8
Entrez Gene ID	5100
Full Name	protocadherin 8
Synonyms	ARCADLIN,PAPC
General protein information	Preferred Names protocadherin 8 Names protocadherin-8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q14.3
Summary	This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008].
Disorder MIM:	603580

mRNA and Protein(s)

mRNA	Protein	Name
NM_032949.2	NP_116567.1	protocadherin-8 isoform 2 precursor
NM_032949.3	NP_116567.1	protocadherin-8 isoform 2 precursor
NM_002590.3	NP_002581.2	protocadherin-8 isoform 1 precursor
NM_002590.4	NP_002581.2	protocadherin-8 isoform 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PCDH8	XP_001136934.1
Bos taurus (cattle)	PCDH8	NP_001179277.1
Gallus gallus (chicken)	PCDH8	NP_001092079.1
Danio rerio (zebrafish)	LOC100002026	XP_001341908.5
Canis lupus familiaris (dog)	PCDH8	XP_542588.2
	PCDH8	XP_001085113.1
Rattus norvegicus (Norway rat)	Pcdh8	NP_074059.1
Xenopus tropicalis (tropical clawed frog)	pcdh8	XP_002938086.1
Homo sapiens (human)	PCDH8	NP_002581.2
Mus musculus (house mouse)	Pcdh8	NP_067518.2

Gene Ontology
Bibliography

Related articles in PubMed

Low Expression of Protocadherin-8 Promotes the Progression of Ovarian Cancer.
Cao Y, Yu Y, Chen X, Ren F, Zhang R, Jia Y, Ren Z, Sun R, Li J, Shi H
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society(2018 Jan)

Protocadherin8 Promotes Invasion and Metastasis via Laminin Subunit ?2 in Gastric Cancer.
Lin Y, Ge X, Zhang X, Wu Z, Liu K, Lin F, Dai C, Guo W, Li J
Cancer science(2018 Jan)

Aberrant Promoter Methylation of Protocadherin8 (PCDH8) in Serum is a Potential Prognostic Marker for Low Gleason Score Prostate Cancer.
Lin YL, Li YL, Ma JG
Medical science monitor : international medical journal of experimental and clinical research234895-4900(2017 Oct)

Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer.
Lin YL, Wang YL, Ma JG, Li WP
Journal of experimental & clinical cancer research : CR3368(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Promoter methylation of protocadherin8 is a frequent event in prostate cancer, and might be used as an independent prognostic factor for biochemical recurrence-free survival in patients with prostate cancer.
Title: Promoter methylation of protocadherin8 is an independent prognostic factor for biochemical recurrence of early-stage prostate cancer.

PCDH8 methylation may be a useful biomarker to predict the progression of clear cell renal cell carcinoma.
Title: Aberrant methylation of PCDH8 is a potential prognostic biomarker for patients with clear cell renal cell carcinoma.

PCDH8 methylation may be associated with tumor progression and poor prognosis in non-muscle invasive bladder cancer.
Title: Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer.

Loss of the PCDH8 gene is one of the probable causes of psychomotor delay in RB1-deleted patients.
Title: Fine mapping of whole RB1 gene deletions in retinoblastoma patients confirms PCDH8 as a candidate gene for psychomotor delay.

study demonstrates the epigenetic inactivation of PCDH8 by promoter methylation and its tumor suppressor function in gastric cancer
Title: Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer.

The following PCDH8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCDH8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17607	NM_002590.4 Latest version!	Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17662	NM_032949.3 Latest version!	Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$657.30 $939.00
View Old Accession Versions >>
OHu17662	NM_032949.2	Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$657.30 $939.00
OHu17607	NM_002590.3	Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCDH8 ( NM_002590.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002581.2 Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17607
Clone ID Related Accession (Same CDS sequence)	NM_002590.3 , NM_002590.4
Accession Version	NM_002590.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-10
Organism	Homo sapiens(human)
Product	protocadherin-8 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036025.1 and AF061573.2. On Mar 1, 2011 this sequence version replaced NM_002590.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF061573.2, SRR1660803.40643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
GTGCGCAAAG GGGGGGCCCT CCGGGAAGAG CGGCCCGGGG CGGCGGGCGG CGGAGCCTCG 
GCTCCCGGCT CCCCGGAGGA GGCCGCCCGG GGAGCCGGGC CCAGGCCCAA CATGTTCGAC 
GTGCTCACCT TCCCTGGCAC CGGCAAAGCG CCCTTTGGCA GCCCCGCGGC GGACGCGCCT 
CCGCCTGCGG TCGCCGCGGC CGAAGTGCCG GGCTCAGAGG GCGGCAGCGC CACTGGGGAA 
AGCGCCTGTC ACTTCGAGGG GCAGCAGCGG CTCCGCGGCG CGCACGCCGA GCCCTACGGT 
GCCTCCCCGG GTTTTGGAAA GGAGCCGGCG CCCCCTGTGG CGGTGTGGAA AGGACACTCC 
TTCAACACCA TTTCTGGCAG AGAAGCAGAG AAGTTCAGCG GCAAAGACAG CGGTAAAGGG 
GACAGTGATT TCAACGACAG CGATTCCGAC ATCAGCGGGG ACGCTCTGAA AAAGGATCTC 
ATCAACCACA TGCAGAGTGG ACTGTGGGCG TGCACCGCTG AGTGTAAGAT CCTGGGCCAC 
TCTGACCGCT GCTGGAGCCC ATCCTGCAGC GGGCCCAACG CACATCCATC GCCTCACCCA 
CCAGCCCAGA TGTCAACCTT CTGTAAGAGC ACGTCACTGC CTCGGGATCC TCTGCGCAGG 
GACAATTACT ACCAGGCCCA GCTGCCCAAG ACAGTGGGGC TGCAGAGCGT CTATGAGAAA 
GTACTGCACA GAGACTATGA CAGGACAGTC ACTCTGCTCT CCCCTCCCCG TCCAGGGAGG 
CTCCCAGACC TGCAGGAGAT TGGAGTACCC CTCTACCAGT CCCCTCCTGG CAGGTACCTG 
TCCCCGAAGA AGGGAGCCAA TGAAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002581.2
CDS	205..3417
Translation	MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPEEAARGAGPRPNMFDVLTFPGTGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYGASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGPNAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPGRYLSPKKGANENV

Target ORF information:

RefSeq Version	NM_002590.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002590.3

ORF Insert Sequence:

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
GTGCGCAAAG GGGGGGCCCT CCGGGAAGAG CGGCCCGGGG CGGCGGGCGG CGGAGCCTCG 
GCTCCCGGCT CCCCGGAGGA GGCCGCCCGG GGAGCCGGGC CCAGGCCCAA CATGTTCGAC 
GTGCTCACCT TCCCTGGCAC CGGCAAAGCG CCCTTTGGCA GCCCCGCGGC GGACGCGCCT 
CCGCCTGCGG TCGCCGCGGC CGAAGTGCCG GGCTCAGAGG GCGGCAGCGC CACTGGGGAA 
AGCGCCTGTC ACTTCGAGGG GCAGCAGCGG CTCCGCGGCG CGCACGCCGA GCCCTACGGT 
GCCTCCCCGG GTTTTGGAAA GGAGCCGGCG CCCCCTGTGG CGGTGTGGAA AGGACACTCC 
TTCAACACCA TTTCTGGCAG AGAAGCAGAG AAGTTCAGCG GCAAAGACAG CGGTAAAGGG 
GACAGTGATT TCAACGACAG CGATTCCGAC ATCAGCGGGG ACGCTCTGAA AAAGGATCTC 
ATCAACCACA TGCAGAGTGG ACTGTGGGCG TGCACCGCTG AGTGTAAGAT CCTGGGCCAC 
TCTGACCGCT GCTGGAGCCC ATCCTGCAGC GGGCCCAACG CACATCCATC GCCTCACCCA 
CCAGCCCAGA TGTCAACCTT CTGTAAGAGC ACGTCACTGC CTCGGGATCC TCTGCGCAGG 
GACAATTACT ACCAGGCCCA GCTGCCCAAG ACAGTGGGGC TGCAGAGCGT CTATGAGAAA 
GTACTGCACA GAGACTATGA CAGGACAGTC ACTCTGCTCT CCCCTCCCCG TCCAGGGAGG 
CTCCCAGACC TGCAGGAGAT TGGAGTACCC CTCTACCAGT CCCCTCCTGG CAGGTACCTG 
TCCCCGAAGA AGGGAGCCAA TGAAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDH8 ( NM_002590.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002581.2 Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17607
Clone ID Related Accession (Same CDS sequence)	NM_002590.3 , NM_002590.4
Accession Version	NM_002590.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	protocadherin-8 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036025.1, AF061573.2 and AL139085.13. On Nov 23, 2018 this sequence version replaced NM_002590.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036025.1, AF061573.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377942.7/ ENSP00000367177.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
GTGCGCAAAG GGGGGGCCCT CCGGGAAGAG CGGCCCGGGG CGGCGGGCGG CGGAGCCTCG 
GCTCCCGGCT CCCCGGAGGA GGCCGCCCGG GGAGCCGGGC CCAGGCCCAA CATGTTCGAC 
GTGCTCACCT TCCCTGGCAC CGGCAAAGCG CCCTTTGGCA GCCCCGCGGC GGACGCGCCT 
CCGCCTGCGG TCGCCGCGGC CGAAGTGCCG GGCTCAGAGG GCGGCAGCGC CACTGGGGAA 
AGCGCCTGTC ACTTCGAGGG GCAGCAGCGG CTCCGCGGCG CGCACGCCGA GCCCTACGGT 
GCCTCCCCGG GTTTTGGAAA GGAGCCGGCG CCCCCTGTGG CGGTGTGGAA AGGACACTCC 
TTCAACACCA TTTCTGGCAG AGAAGCAGAG AAGTTCAGCG GCAAAGACAG CGGTAAAGGG 
GACAGTGATT TCAACGACAG CGATTCCGAC ATCAGCGGGG ACGCTCTGAA AAAGGATCTC 
ATCAACCACA TGCAGAGTGG ACTGTGGGCG TGCACCGCTG AGTGTAAGAT CCTGGGCCAC 
TCTGACCGCT GCTGGAGCCC ATCCTGCAGC GGGCCCAACG CACATCCATC GCCTCACCCA 
CCAGCCCAGA TGTCAACCTT CTGTAAGAGC ACGTCACTGC CTCGGGATCC TCTGCGCAGG 
GACAATTACT ACCAGGCCCA GCTGCCCAAG ACAGTGGGGC TGCAGAGCGT CTATGAGAAA 
GTACTGCACA GAGACTATGA CAGGACAGTC ACTCTGCTCT CCCCTCCCCG TCCAGGGAGG 
CTCCCAGACC TGCAGGAGAT TGGAGTACCC CTCTACCAGT CCCCTCCTGG CAGGTACCTG 
TCCCCGAAGA AGGGAGCCAA TGAAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002581.2
CDS	205..3417
Translation	MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPEEAARGAGPRPNMFDVLTFPGTGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYGASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGPNAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPGRYLSPKKGANENV

Target ORF information:

RefSeq Version	NM_002590.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002590.4

ORF Insert Sequence:

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
GTGCGCAAAG GGGGGGCCCT CCGGGAAGAG CGGCCCGGGG CGGCGGGCGG CGGAGCCTCG 
GCTCCCGGCT CCCCGGAGGA GGCCGCCCGG GGAGCCGGGC CCAGGCCCAA CATGTTCGAC 
GTGCTCACCT TCCCTGGCAC CGGCAAAGCG CCCTTTGGCA GCCCCGCGGC GGACGCGCCT 
CCGCCTGCGG TCGCCGCGGC CGAAGTGCCG GGCTCAGAGG GCGGCAGCGC CACTGGGGAA 
AGCGCCTGTC ACTTCGAGGG GCAGCAGCGG CTCCGCGGCG CGCACGCCGA GCCCTACGGT 
GCCTCCCCGG GTTTTGGAAA GGAGCCGGCG CCCCCTGTGG CGGTGTGGAA AGGACACTCC 
TTCAACACCA TTTCTGGCAG AGAAGCAGAG AAGTTCAGCG GCAAAGACAG CGGTAAAGGG 
GACAGTGATT TCAACGACAG CGATTCCGAC ATCAGCGGGG ACGCTCTGAA AAAGGATCTC 
ATCAACCACA TGCAGAGTGG ACTGTGGGCG TGCACCGCTG AGTGTAAGAT CCTGGGCCAC 
TCTGACCGCT GCTGGAGCCC ATCCTGCAGC GGGCCCAACG CACATCCATC GCCTCACCCA 
CCAGCCCAGA TGTCAACCTT CTGTAAGAGC ACGTCACTGC CTCGGGATCC TCTGCGCAGG 
GACAATTACT ACCAGGCCCA GCTGCCCAAG ACAGTGGGGC TGCAGAGCGT CTATGAGAAA 
GTACTGCACA GAGACTATGA CAGGACAGTC ACTCTGCTCT CCCCTCCCCG TCCAGGGAGG 
CTCCCAGACC TGCAGGAGAT TGGAGTACCC CTCTACCAGT CCCCTCCTGG CAGGTACCTG 
TCCCCGAAGA AGGGAGCCAA TGAAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDH8 ( NM_032949.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_116567.1 Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17662
Clone ID Related Accession (Same CDS sequence)	NM_032949.2 , NM_032949.3
Accession Version	NM_032949.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2922bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protocadherin-8 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036025.1, AY013873.1 and AF061573.2. On Mar 1, 2011 this sequence version replaced NM_032949.1. Transcript Variant: This variant (2) uses an alternative splice site on exon 1, truncating the portion encoding the cytoplasmic domain. As a result, isoform 2 has a shorter cytoplasmic tail, while still sharing a C terminus with isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY013873.1, SRR1660807.253237.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
CCCTACGGTG CCTCCCCGGG TTTTGGAAAG GAGCCGGCGC CCCCTGTGGC GGTGTGGAAA 
GGACACTCCT TCAACACCAT TTCTGGCAGA GAAGCAGAGA AGTTCAGCGG CAAAGACAGC 
GGTAAAGGGG ACAGTGATTT CAACGACAGC GATTCCGACA TCAGCGGGGA CGCTCTGAAA 
AAGGATCTCA TCAACCACAT GCAGAGTGGA CTGTGGGCGT GCACCGCTGA GTGTAAGATC 
CTGGGCCACT CTGACCGCTG CTGGAGCCCA TCCTGCAGCG GGCCCAACGC ACATCCATCG 
CCTCACCCAC CAGCCCAGAT GTCAACCTTC TGTAAGAGCA CGTCACTGCC TCGGGATCCT 
CTGCGCAGGG ACAATTACTA CCAGGCCCAG CTGCCCAAGA CAGTGGGGCT GCAGAGCGTC 
TATGAGAAAG TACTGCACAG AGACTATGAC AGGACAGTCA CTCTGCTCTC CCCTCCCCGT 
CCAGGGAGGC TCCCAGACCT GCAGGAGATT GGAGTACCCC TCTACCAGTC CCCTCCTGGC 
AGGTACCTGT CCCCGAAGAA GGGAGCCAAT GAAAATGTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116567.1
CDS	205..3126
Translation	MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEPYGASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGPNAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPGRYLSPKKGANENV

Target ORF information:

RefSeq Version	NM_032949.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032949.2

ORF Insert Sequence:

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
CCCTACGGTG CCTCCCCGGG TTTTGGAAAG GAGCCGGCGC CCCCTGTGGC GGTGTGGAAA 
GGACACTCCT TCAACACCAT TTCTGGCAGA GAAGCAGAGA AGTTCAGCGG CAAAGACAGC 
GGTAAAGGGG ACAGTGATTT CAACGACAGC GATTCCGACA TCAGCGGGGA CGCTCTGAAA 
AAGGATCTCA TCAACCACAT GCAGAGTGGA CTGTGGGCGT GCACCGCTGA GTGTAAGATC 
CTGGGCCACT CTGACCGCTG CTGGAGCCCA TCCTGCAGCG GGCCCAACGC ACATCCATCG 
CCTCACCCAC CAGCCCAGAT GTCAACCTTC TGTAAGAGCA CGTCACTGCC TCGGGATCCT 
CTGCGCAGGG ACAATTACTA CCAGGCCCAG CTGCCCAAGA CAGTGGGGCT GCAGAGCGTC 
TATGAGAAAG TACTGCACAG AGACTATGAC AGGACAGTCA CTCTGCTCTC CCCTCCCCGT 
CCAGGGAGGC TCCCAGACCT GCAGGAGATT GGAGTACCCC TCTACCAGTC CCCTCCTGGC 
AGGTACCTGT CCCCGAAGAA GGGAGCCAAT GAAAATGTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDH8 ( NM_032949.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116567.1 Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17662
Clone ID Related Accession (Same CDS sequence)	NM_032949.2 , NM_032949.3
Accession Version	NM_032949.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2922bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	protocadherin-8 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036025.1, AY013873.1, AF061573.2 and AL139085.13. On May 31, 2019 this sequence version replaced NM_032949.2. Transcript Variant: This variant (2) uses an alternative splice site on exon 1, truncating the portion encoding the cytoplasmic domain. As a result, isoform 2 has a shorter cytoplasmic tail, while still sharing a C terminus with isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY013873.1, SRR1660807.253237.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
CCCTACGGTG CCTCCCCGGG TTTTGGAAAG GAGCCGGCGC CCCCTGTGGC GGTGTGGAAA 
GGACACTCCT TCAACACCAT TTCTGGCAGA GAAGCAGAGA AGTTCAGCGG CAAAGACAGC 
GGTAAAGGGG ACAGTGATTT CAACGACAGC GATTCCGACA TCAGCGGGGA CGCTCTGAAA 
AAGGATCTCA TCAACCACAT GCAGAGTGGA CTGTGGGCGT GCACCGCTGA GTGTAAGATC 
CTGGGCCACT CTGACCGCTG CTGGAGCCCA TCCTGCAGCG GGCCCAACGC ACATCCATCG 
CCTCACCCAC CAGCCCAGAT GTCAACCTTC TGTAAGAGCA CGTCACTGCC TCGGGATCCT 
CTGCGCAGGG ACAATTACTA CCAGGCCCAG CTGCCCAAGA CAGTGGGGCT GCAGAGCGTC 
TATGAGAAAG TACTGCACAG AGACTATGAC AGGACAGTCA CTCTGCTCTC CCCTCCCCGT 
CCAGGGAGGC TCCCAGACCT GCAGGAGATT GGAGTACCCC TCTACCAGTC CCCTCCTGGC 
AGGTACCTGT CCCCGAAGAA GGGAGCCAAT GAAAATGTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116567.1
CDS	205..3126
Translation	MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEPYGASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGPNAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPGRYLSPKKGANENV

Target ORF information:

RefSeq Version	NM_032949.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin 8 (PCDH8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032949.3

ORF Insert Sequence:

ATGAGTCCTG TGAGGCGTTG GGGCAGCCCC TGCCTTTTCC CCTTGCAGCT CTTCAGCCTC 
TGCTGGGTGC TCTCAGTGGC CCAGAGCAAA ACAGTCCGAT ACAGCACCTT CGAGGAGGAT 
GCCCCCGGCA CGGTCATCGG GACCCTGGCC GAGGACCTGC ATATGAAAGT ATCGGGTGAC 
ACAAGCTTCC GCCTGATGAA GCAATTCAAC AGCTCTCTGC TCCGGGTGCG CGAAGGCGAC 
GGGCAGCTGA CCGTCGGGGA CGCCGGCCTG GACCGCGAGC GGCTGTGTGG CCAGGCCCCG 
CAGTGCGTGC TGGCCTTCGA TGTGGTCAGC TTCTCGCAGG AGCAGTTCCG GCTGGTGCAC 
GTGGAGGTAG AGGTGAGGGA CGTCAACGAC CACGCGCCGC GCTTCCCCAG GGCCCAGATC 
CCGGTAGAGG TGTCCGAGGG TGCGGCAGTG GGCACGCGCA TCCCCTTGGA GGTGCCGGTG 
GACGAGGACG TGGGCGCCAA CGGGCTGCAG ACCGTGCGCC TGGCCGAGCC GCACAGCCCC 
TTTCGCGTGG AGCTGCAGAC GCGAGCGGAC GGCGCTCAGT GCGCAGACCT GGTGCTGCTG 
CAGGAGCTGG ACCGCGAGAG CCAGGCCGCC TACAGCCTGG AGCTGGTGGC CCAGGACGGC 
GGCCGCCCGC CGCGCTCCGC CACGGCTGCC CTCAGCGTGC GCGTCCTGGA TGCGAATGAC 
CACAGCCCGG CCTTCCCGCA GGGCGCCGTG GCCGAAGTGG AGCTGGCGGA AGACGCGCCC 
GTGGGCTCCC TGCTTCTCGA CCTGGACGCA GCCGACCCCG ACGAGGGACC TAACGGCGAC 
GTGGTGTTCG CATTTGGCGC CCGCACCCCG CCGGAGGCGC GCCGCCTCTT TCGGCTTGAC 
CCGCGATCAG GCCGCCTCAC CCTGGCCGGG CCCGTGGACT ACGAGCGTCA GGACACCTAC 
GAGCTGGACG TGCGGGCGCA GGACCGCGGA CCCGGGCCCC GCGCTGCCAC CTGCAAGGTC 
ATCGTGCGCA TCCGAGACGT CAATGACAAC GCACCCGACA TCGCCATCAC CCCGCTGGCC 
GCCCCAGGCG CGCCGGCAAC CTCACCCTTC GCCGCTGCCG CCGCCGCCGC TGCACTCGGG 
GGAGCGGACG CTAGCTCGCC GGCGGGAGCC GGGACGCCGG AGGCTGGTGC CACTTCGCTG 
GTGCCGGAGG GGGCGGCGCG CGAGAGCCTG GTGGCCCTGG TCAGCACCTC GGACAGGGAC 
TCGGGCGCCA ACGGGCAAGT GCGCTGCGCC CTCTATGGGC ACGAGCACTT CCGGCTGCAG 
CCGGCCTACG CGGGCAGCTA CCTGGTGGTG ACCGCGGCGT CGCTGGACCG CGAACGCATC 
GCCGAGTACA ACTTGACGCT GGTGGCCGAG GATCGCGGCG CGCCCCCGCT GCGCACAGTG 
CGGCCCTACA CGGTGCGTGT GGGCGACGAG AACGACAACG CGCCGCTCTT CACGCGGCCG 
GTCTATGAGG TGTCGGTGCG CGAGAACAAC CCGCCAGGCG CCTACCTGGC CACGGTGGCC 
GCCCGCGACC GGGACCTGGG CCGCAACGGC CAGGTCACCT ACCGGCTGCT GGAGGCCGAG 
GTGGGCCGCG CCGGGGGCGC CGTGTCCACT TATGTCTCGG TGGACCCAGC TACCGGAGCC 
ATCTACGCGC TGCGCAGCTT CGACTATGAG ACGCTGCGCC AACTCGACGT TCGCATCCAA 
GCTAGCGACG GCGGCTCCCC TCAGCTTTCC AGCAGCGCCC TAGTGCAAGT GCGCGTGCTG 
GACCAGAACG ACCATGCGCC AGTCCTGGTG CACCCGGCGC CAGCCAATGG CTCCCTAGAA 
GTGGCGGTGC CTGGGCGCAC CGCAAAGGAC ACGGTTGTGG CCCGTGTGCA GGCCCGGGAT 
GCAGACGAGG GAGCCAACGG GGAGCTGGCG TTCGAGCTGC AGCAGCAGGA GCCGCGCGAA 
GCCTTCGCCA TCGGCCGCCG CACGGGGGAG ATACTGCTCA CCGGCGACCT CTCGCAGGAG 
CCACCCGGTC GCGTGTTCAG GGCGCTCCTG GTCATATCCG ACGGCGGCCG TCCCCCGCTC 
ACCACCACCG CAACTGTCAG CTTCGTGGTA ACAGCAGGGG GCGGGCGTGG GCCGGCTGCG 
CCTGCCAGTG CAGGAAGCCC GGAGCGTTCC CGCCCGCCTG GCTCTCGGCT CGGGGTGTCC 
GGGTCGGTGC TGCAATGGGA CACGCCGCTG ATCGTCATCA TCGTGCTGGC CGGGAGCTGC 
ACGCTGCTGC TGGCCGCCAT CATCGCCATC GCCACCACCT GCAACCGCCG CAAGAAGGAG 
CCCTACGGTG CCTCCCCGGG TTTTGGAAAG GAGCCGGCGC CCCCTGTGGC GGTGTGGAAA 
GGACACTCCT TCAACACCAT TTCTGGCAGA GAAGCAGAGA AGTTCAGCGG CAAAGACAGC 
GGTAAAGGGG ACAGTGATTT CAACGACAGC GATTCCGACA TCAGCGGGGA CGCTCTGAAA 
AAGGATCTCA TCAACCACAT GCAGAGTGGA CTGTGGGCGT GCACCGCTGA GTGTAAGATC 
CTGGGCCACT CTGACCGCTG CTGGAGCCCA TCCTGCAGCG GGCCCAACGC ACATCCATCG 
CCTCACCCAC CAGCCCAGAT GTCAACCTTC TGTAAGAGCA CGTCACTGCC TCGGGATCCT 
CTGCGCAGGG ACAATTACTA CCAGGCCCAG CTGCCCAAGA CAGTGGGGCT GCAGAGCGTC 
TATGAGAAAG TACTGCACAG AGACTATGAC AGGACAGTCA CTCTGCTCTC CCCTCCCCGT 
CCAGGGAGGC TCCCAGACCT GCAGGAGATT GGAGTACCCC TCTACCAGTC CCCTCCTGGC 
AGGTACCTGT CCCCGAAGAA GGGAGCCAAT GAAAATGTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Low Expression of Protocadherin-8 Promotes the Progression of Ovarian Cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society(2018 Jan)
Cao Y,Yu Y,Chen X,Ren F,Zhang R,Jia Y,Ren Z,Sun R,Li J,Shi H

Protocadherin8 Promotes Invasion and Metastasis via Laminin Subunit ?2 in Gastric Cancer.
Cancer science(2018 Jan)
Lin Y,Ge X,Zhang X,Wu Z,Liu K,Lin F,Dai C,Guo W,Li J

Aberrant Promoter Methylation of Protocadherin8 (PCDH8) in Serum is a Potential Prognostic Marker for Low Gleason Score Prostate Cancer.
Medical science monitor : international medical journal of experimental and clinical research234895-4900(2017 Oct)
Lin YL,Li YL,Ma JG

Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer.
Journal of experimental & clinical cancer research : CR3368(2014 Aug)
Lin YL,Wang YL,Ma JG,Li WP