IRX4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IRX4
Entrez Gene ID	50805
Full Name	iroquois homeobox 4
Synonyms	IRXA3
General protein information	Preferred Names iroquois homeobox 4 Names iroquois-class homeodomain protein IRX-4 homeodomain protein IRXA3 iroquois homeobox protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p15.33
Disorder MIM:	606199

mRNA and Protein(s)

mRNA	Protein	Name
NM_001278632.1	NP_001265561.1	iroquois-class homeodomain protein IRX-4 isoform b
NM_016358.3	NP_057442.1	iroquois-class homeodomain protein IRX-4 isoform b
NM_001278635.1	NP_001265564.1	iroquois-class homeodomain protein IRX-4 isoform a
NM_016358.2	NP_057442.1	iroquois-class homeodomain protein IRX-4 isoform b
NM_001278634.2	NP_001265563.1	iroquois-class homeodomain protein IRX-4 isoform b
NM_001278633.1	NP_001265562.1	iroquois-class homeodomain protein IRX-4 isoform a
NM_001278634.1	NP_001265563.1	iroquois-class homeodomain protein IRX-4 isoform b

Pathways from BioSystems

Homologies

Homo sapiens (human)	IRX4	NP_001265562.1
Rattus norvegicus (Norway rat)	Irx4	NP_001100800.1
Danio rerio (zebrafish)	irx4a	NP_991261.1
	IRX4	XP_001097842.1
Mus musculus (house mouse)	Irx4	NP_061373.1
Gallus gallus (chicken)	IRX4	NP_001001744.1
Xenopus tropicalis (tropical clawed frog)	irx4	NP_001263621.1
Bos taurus (cattle)	IRX4	NP_001091936.1

Gene Ontology
Bibliography

Related articles in PubMed

Variants at IRX4 as prostate cancer expression quantitative trait loci.
Xu X, Hussain WM, Vijai J, Offit K, Rubin MA, Demichelis F, Klein RJ
European journal of human genetics : EJHG22(4)558-63(2014 Apr)

IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Nguyen HH, Takata R, Akamatsu S, Shigemizu D, Tsunoda T, Furihata M, Takahashi A, Kubo M, Kamatani N, Ogawa O, Fujioka T, Nakamura Y, Nakagawa H
Human molecular genetics21(9)2076-85(2012 May)

Two novel mutations of the IRX4 gene in patients with congenital heart disease.
Cheng Z, Wang J, Su D, Pan H, Huang G, Li X, Li Z, Shen A, Xie X, Wang B, Ma X
Human genetics130(5)657-62(2011 Nov)

Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
Sch?rks M, Buring JE, Ridker PM, Chasman DI, Kurth T
PloS one6(7)e22106(2011)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We independently validated IRX4 as a potential prostate cancer risk gene through cis-expression quantitative trait loci analysis of prostate cancer risk variants.
Title: Variants at IRX4 as prostate cancer expression quantitative trait loci.

the prostate cancer (PC)-susceptibility locus represented by rs12653946 at 5p15 is likely to regulate IRX4 expression in prostate which could suppress PC growth by interacting with the VDR pathway, conferring to PC susceptibility
Title: IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.

IRX4 had a potential causative impact on the development of congenital heart disease, particularly ventricular septal defect.
Title: Two novel mutations of the IRX4 gene in patients with congenital heart disease.

Among migraineurs with aura rs7698623 in MEPE (OR = 6.37; 95% CI 3.15-12.90; p = 2.7x10(-7)) and rs4975709 in IRX4 (OR = 5.06; 95% CI 2.66-9.62; p = 7.7x10(-7)) appeared to be associated with ischemic stroke.
Title: Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

The following IRX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07143	NM_016358.3 Latest version!	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu07143	NM_001278634.2 Latest version!	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu07143	NM_001278632.1 Latest version!	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu11442	NM_001278635.1 Latest version!	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu11442	NM_001278633.1 Latest version!	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu07143	NM_016358.2	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu07143	NM_001278634.1	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IRX4 ( NM_001278632.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265561.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07143
Clone ID Related Accession (Same CDS sequence)	NM_001278632.1 , NM_016358.3 , NM_016358.2 , NM_001278634.2 , NM_001278634.1
Accession Version	NM_001278632.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025183.5, AB690778.1 and AI566193.1. Transcript Variant: This variant (1) differs in the 5' UTR and lacks an alternate internal exon compared to variant 4. It encodes isoform b which is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB690778.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145893 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265561.1
CDS	219..1778
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_001278632.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278632.1

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_016358.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057442.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu07143
Clone ID Related Accession (Same CDS sequence)	NM_001278632.1 , NM_016358.3 , NM_016358.2 , NM_001278634.2 , NM_001278634.1
Accession Version	NM_016358.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025183.5, AF124733.1, BC136505.1, BC110912.1 and AI566193.1. On Nov 23, 2018 this sequence version replaced NM_016358.2. Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate internal exon compared to variant 4. It encodes isoform b which is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF124733.1, BC110912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267757 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000231357.7/ ENSP00000231357.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057442.1
CDS	279..1838
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_016358.3
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016358.3

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_016358.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_057442.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu07143
Clone ID Related Accession (Same CDS sequence)	NM_001278632.1 , NM_016358.3 , NM_016358.2 , NM_001278634.2 , NM_001278634.1
Accession Version	NM_016358.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF124733.1, BC136505.1, BC110912.1 and AI566193.1. On Jun 28, 2008 this sequence version replaced NM_016358.1. Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate internal exon compared to variant 4. It encodes isoform b which is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: AF124733.1, BC110912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267757 [ECO:0000348] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057442.1
CDS	120..1679
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_016358.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016358.2

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_001278634.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265563.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu07143
Clone ID Related Accession (Same CDS sequence)	NM_001278632.1 , NM_016358.3 , NM_016358.2 , NM_001278634.2 , NM_001278634.1
Accession Version	NM_001278634.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB690780.1, AI566193.1 and AC025183.5. On May 31, 2019 this sequence version replaced NM_001278634.1. Transcript Variant: This variant (3) lacks an alternate internal exon compared to variant 4. It encodes isoform b, which is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB690780.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145893 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265563.1
CDS	185..1744
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_001278634.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278634.2

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_001278634.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265563.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu07143
Clone ID Related Accession (Same CDS sequence)	NM_001278632.1 , NM_016358.3 , NM_016358.2 , NM_001278634.2 , NM_001278634.1
Accession Version	NM_001278634.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025183.5, AB690780.1 and AI566193.1. Transcript Variant: This variant (3) lacks an alternate internal exon compared to variant 4. It encodes isoform b, which is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB690780.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145893 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265563.1
CDS	224..1783
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_001278634.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278634.1

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGTA TGGAACCATG 
GACAGCGGCA CGCGGCGCAA GAACGCCACG CGCGAGACCA CCAGCACGCT CAAGGCCTGG 
CTGCAGGAGC ACCGCAAGAA CCCCTACCCC ACCAAGGGCG AGAAGATCAT GCTGGCCATC 
ATCACCAAGA TGACCCTCAC ACAGGTCTCC ACCTGGTTCG CCAACGCGCG CCGGCGCCTC 
AAGAAGGAGA ACAAGATGAC GTGGCCGCCG CGGAACAAGT GCGCAGACGA GAAGCGGCCC 
TACGCGGAGG GCGAGGAGGA GGAGGGGGGC GAGGAGGAGG CGCGGGAGGA GCCCCTCAAG 
AGCTCCAAGA ACGCAGAGCC CGTGGGCAAA GAGGAGAAGG AGCTGGAGCT TAGTGACTTG 
GACGACTTCG ACCCGCTGGA AGCAGAGCCG CCGGCGTGCG AGCTGAAGCC GCCCTTCCAC 
TCCCTGGACG GCGGTCTGGA GCGCGTCCCC GCCGCGCCCG ACGGCCCGGT CAAGGAGGCC 
TCAGGCGCGC TCCGGATGTC TCTGGCCGCG GGTGGCGGAG CTGCTCTGGA CGAGGACCTG 
GAGAGGGCCC GGAGCTGTCT CCGCAGCGCG GCGGCCGGGC CGGAGCCACT GCCGGGCGCA 
GAGGGCGGCC CTCAGGTCTG CGAGGCCAAG CTGGGGTTTG TGCCGGCGGG GGCGTCGGCA 
GGCCTGGAGG CTAAGCCGCG CATCTGGTCC CTGGCCCACA CAGCCACCGC CGCCGCCGCC 
GCCGCCACCT CCCTGAGCCA GACTGAGTTT CCGTCGTGCA TGCTCAAGCG CCAAGGTCCC 
GCGGCCCCTG CGGCTGTGTC CTCCGCGCCC GCCACGTCCC CGTCTGTGGC CCTTCCCCAC 
TCTGGCGCCC TGGACAGGCA CCAGGACTCC CCGGTAACCA GTCTCAGAAA CTGGGTGGAC 
GGGGTCTTCC ACGACCCCAT CCTCAGGCAC AGCACTTTGA ACCAGGCCTG GGCCACCGCC 
AAGGGCGCCC TCCTGGACCC CGGGCCTCTG GGACGCTCGC TGGGGGCGGG CGCGAACGTG 
CTGACTGCAC CCCTGGCCCG CGCCTTTCCG CCTGCCGTGC CCCAGGACGC CCCAGCTGCA 
GGCGCCGCCA GGGAGCTGCT CGCCCTGCCC AAGGCCGGCG GCAAACCCTT CTGCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_001278635.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265564.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu11442
Clone ID Related Accession (Same CDS sequence)	NM_001278635.1 , NM_001278633.1
Accession Version	NM_001278635.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025183.5, AB690781.1 and AI566193.1. Transcript Variant: This variant (4) represents the longest transcript. Both variants 2 and 4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB690781.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145893 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGAT CAAACGGCTA 
GGCGGTCATC CCCATAAAGG AATTGGCCTG GACCTCTCTG GCTTGGGAAG GAGCCCAGGC 
TCCCTGTATG GAACCATGGA CAGCGGCACG CGGCGCAAGA ACGCCACGCG CGAGACCACC 
AGCACGCTCA AGGCCTGGCT GCAGGAGCAC CGCAAGAACC CCTACCCCAC CAAGGGCGAG 
AAGATCATGC TGGCCATCAT CACCAAGATG ACCCTCACAC AGGTCTCCAC CTGGTTCGCC 
AACGCGCGCC GGCGCCTCAA GAAGGAGAAC AAGATGACGT GGCCGCCGCG GAACAAGTGC 
GCAGACGAGA AGCGGCCCTA CGCGGAGGGC GAGGAGGAGG AGGGGGGCGA GGAGGAGGCG 
CGGGAGGAGC CCCTCAAGAG CTCCAAGAAC GCAGAGCCCG TGGGCAAAGA GGAGAAGGAG 
CTGGAGCTTA GTGACTTGGA CGACTTCGAC CCGCTGGAAG CAGAGCCGCC GGCGTGCGAG 
CTGAAGCCGC CCTTCCACTC CCTGGACGGC GGTCTGGAGC GCGTCCCCGC CGCGCCCGAC 
GGCCCGGTCA AGGAGGCCTC AGGCGCGCTC CGGATGTCTC TGGCCGCGGG TGGCGGAGCT 
GCTCTGGACG AGGACCTGGA GAGGGCCCGG AGCTGTCTCC GCAGCGCGGC GGCCGGGCCG 
GAGCCACTGC CGGGCGCAGA GGGCGGCCCT CAGGTCTGCG AGGCCAAGCT GGGGTTTGTG 
CCGGCGGGGG CGTCGGCAGG CCTGGAGGCT AAGCCGCGCA TCTGGTCCCT GGCCCACACA 
GCCACCGCCG CCGCCGCCGC CGCCACCTCC CTGAGCCAGA CTGAGTTTCC GTCGTGCATG 
CTCAAGCGCC AAGGTCCCGC GGCCCCTGCG GCTGTGTCCT CCGCGCCCGC CACGTCCCCG 
TCTGTGGCCC TTCCCCACTC TGGCGCCCTG GACAGGCACC AGGACTCCCC GGTAACCAGT 
CTCAGAAACT GGGTGGACGG GGTCTTCCAC GACCCCATCC TCAGGCACAG CACTTTGAAC 
CAGGCCTGGG CCACCGCCAA GGGCGCCCTC CTGGACCCCG GGCCTCTGGG ACGCTCGCTG 
GGGGCGGGCG CGAACGTGCT GACTGCACCC CTGGCCCGCG CCTTTCCGCC TGCCGTGCCC 
CAGGACGCCC CAGCTGCAGG CGCCGCCAGG GAGCTGCTCG CCCTGCCCAA GGCCGGCGGC 
AAACCCTTCT GCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265564.1
CDS	224..1861
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRIKRLGGHPHKGIGLDLSGLGRSPGSLYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_001278635.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278635.1

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGAT CAAACGGCTA 
GGCGGTCATC CCCATAAAGG AATTGGCCTG GACCTCTCTG GCTTGGGAAG GAGCCCAGGC 
TCCCTGTATG GAACCATGGA CAGCGGCACG CGGCGCAAGA ACGCCACGCG CGAGACCACC 
AGCACGCTCA AGGCCTGGCT GCAGGAGCAC CGCAAGAACC CCTACCCCAC CAAGGGCGAG 
AAGATCATGC TGGCCATCAT CACCAAGATG ACCCTCACAC AGGTCTCCAC CTGGTTCGCC 
AACGCGCGCC GGCGCCTCAA GAAGGAGAAC AAGATGACGT GGCCGCCGCG GAACAAGTGC 
GCAGACGAGA AGCGGCCCTA CGCGGAGGGC GAGGAGGAGG AGGGGGGCGA GGAGGAGGCG 
CGGGAGGAGC CCCTCAAGAG CTCCAAGAAC GCAGAGCCCG TGGGCAAAGA GGAGAAGGAG 
CTGGAGCTTA GTGACTTGGA CGACTTCGAC CCGCTGGAAG CAGAGCCGCC GGCGTGCGAG 
CTGAAGCCGC CCTTCCACTC CCTGGACGGC GGTCTGGAGC GCGTCCCCGC CGCGCCCGAC 
GGCCCGGTCA AGGAGGCCTC AGGCGCGCTC CGGATGTCTC TGGCCGCGGG TGGCGGAGCT 
GCTCTGGACG AGGACCTGGA GAGGGCCCGG AGCTGTCTCC GCAGCGCGGC GGCCGGGCCG 
GAGCCACTGC CGGGCGCAGA GGGCGGCCCT CAGGTCTGCG AGGCCAAGCT GGGGTTTGTG 
CCGGCGGGGG CGTCGGCAGG CCTGGAGGCT AAGCCGCGCA TCTGGTCCCT GGCCCACACA 
GCCACCGCCG CCGCCGCCGC CGCCACCTCC CTGAGCCAGA CTGAGTTTCC GTCGTGCATG 
CTCAAGCGCC AAGGTCCCGC GGCCCCTGCG GCTGTGTCCT CCGCGCCCGC CACGTCCCCG 
TCTGTGGCCC TTCCCCACTC TGGCGCCCTG GACAGGCACC AGGACTCCCC GGTAACCAGT 
CTCAGAAACT GGGTGGACGG GGTCTTCCAC GACCCCATCC TCAGGCACAG CACTTTGAAC 
CAGGCCTGGG CCACCGCCAA GGGCGCCCTC CTGGACCCCG GGCCTCTGGG ACGCTCGCTG 
GGGGCGGGCG CGAACGTGCT GACTGCACCC CTGGCCCGCG CCTTTCCGCC TGCCGTGCCC 
CAGGACGCCC CAGCTGCAGG CGCCGCCAGG GAGCTGCTCG CCCTGCCCAA GGCCGGCGGC 
AAACCCTTCT GCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX4 ( NM_001278633.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265562.1 Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11442
Clone ID Related Accession (Same CDS sequence)	NM_001278635.1 , NM_001278633.1
Accession Version	NM_001278633.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-4 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025183.5, AB690779.1 and AI566193.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 4. Both variants 2 and 4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB690779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145893 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGAT CAAACGGCTA 
GGCGGTCATC CCCATAAAGG AATTGGCCTG GACCTCTCTG GCTTGGGAAG GAGCCCAGGC 
TCCCTGTATG GAACCATGGA CAGCGGCACG CGGCGCAAGA ACGCCACGCG CGAGACCACC 
AGCACGCTCA AGGCCTGGCT GCAGGAGCAC CGCAAGAACC CCTACCCCAC CAAGGGCGAG 
AAGATCATGC TGGCCATCAT CACCAAGATG ACCCTCACAC AGGTCTCCAC CTGGTTCGCC 
AACGCGCGCC GGCGCCTCAA GAAGGAGAAC AAGATGACGT GGCCGCCGCG GAACAAGTGC 
GCAGACGAGA AGCGGCCCTA CGCGGAGGGC GAGGAGGAGG AGGGGGGCGA GGAGGAGGCG 
CGGGAGGAGC CCCTCAAGAG CTCCAAGAAC GCAGAGCCCG TGGGCAAAGA GGAGAAGGAG 
CTGGAGCTTA GTGACTTGGA CGACTTCGAC CCGCTGGAAG CAGAGCCGCC GGCGTGCGAG 
CTGAAGCCGC CCTTCCACTC CCTGGACGGC GGTCTGGAGC GCGTCCCCGC CGCGCCCGAC 
GGCCCGGTCA AGGAGGCCTC AGGCGCGCTC CGGATGTCTC TGGCCGCGGG TGGCGGAGCT 
GCTCTGGACG AGGACCTGGA GAGGGCCCGG AGCTGTCTCC GCAGCGCGGC GGCCGGGCCG 
GAGCCACTGC CGGGCGCAGA GGGCGGCCCT CAGGTCTGCG AGGCCAAGCT GGGGTTTGTG 
CCGGCGGGGG CGTCGGCAGG CCTGGAGGCT AAGCCGCGCA TCTGGTCCCT GGCCCACACA 
GCCACCGCCG CCGCCGCCGC CGCCACCTCC CTGAGCCAGA CTGAGTTTCC GTCGTGCATG 
CTCAAGCGCC AAGGTCCCGC GGCCCCTGCG GCTGTGTCCT CCGCGCCCGC CACGTCCCCG 
TCTGTGGCCC TTCCCCACTC TGGCGCCCTG GACAGGCACC AGGACTCCCC GGTAACCAGT 
CTCAGAAACT GGGTGGACGG GGTCTTCCAC GACCCCATCC TCAGGCACAG CACTTTGAAC 
CAGGCCTGGG CCACCGCCAA GGGCGCCCTC CTGGACCCCG GGCCTCTGGG ACGCTCGCTG 
GGGGCGGGCG CGAACGTGCT GACTGCACCC CTGGCCCGCG CCTTTCCGCC TGCCGTGCCC 
CAGGACGCCC CAGCTGCAGG CGCCGCCAGG GAGCTGCTCG CCCTGCCCAA GGCCGGCGGC 
AAACCCTTCT GCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265562.1
CDS	219..1856
Translation	MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRIKRLGGHPHKGIGLDLSGLGRSPGSLYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA

Target ORF information:

RefSeq Version	NM_001278633.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 4 (IRX4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278633.1

ORF Insert Sequence:

ATGTCCTACC CGCAGTTTGG ATACCCCTAC TCCTCGGCTC CCCAGTTCTT GATGGCCACC 
AACTCCCTGA GCACGTGCTG CGAGTCCGGA GGCCGCACGC TGGCGGACTC CGGGCCCGCC 
GCCTCGGCCC AGGCGCCGGT CTACTGCCCG GTCTACGAGA GCCGGCTGCT GGCCACCGCG 
CGCCACGAGC TCAACTCGGC CGCGGCGCTG GGCGTCTATG GGGGTCCCTA TGGCGGATCG 
CAGGGCTATG GCAACTACGT GACCTACGGC TCGGAGGCGT CCGCCTTCTA CTCGCTGAAC 
AGCTTTGATT CCAAGGATGG TTCGGGATCT GCGCATGGGG GCCTGGCACC AGCCGCTGCC 
GCCTACTACC CTTACGAGCC AGCTCTGGGC CAGTACCCCT ATGACAGGAT CAAACGGCTA 
GGCGGTCATC CCCATAAAGG AATTGGCCTG GACCTCTCTG GCTTGGGAAG GAGCCCAGGC 
TCCCTGTATG GAACCATGGA CAGCGGCACG CGGCGCAAGA ACGCCACGCG CGAGACCACC 
AGCACGCTCA AGGCCTGGCT GCAGGAGCAC CGCAAGAACC CCTACCCCAC CAAGGGCGAG 
AAGATCATGC TGGCCATCAT CACCAAGATG ACCCTCACAC AGGTCTCCAC CTGGTTCGCC 
AACGCGCGCC GGCGCCTCAA GAAGGAGAAC AAGATGACGT GGCCGCCGCG GAACAAGTGC 
GCAGACGAGA AGCGGCCCTA CGCGGAGGGC GAGGAGGAGG AGGGGGGCGA GGAGGAGGCG 
CGGGAGGAGC CCCTCAAGAG CTCCAAGAAC GCAGAGCCCG TGGGCAAAGA GGAGAAGGAG 
CTGGAGCTTA GTGACTTGGA CGACTTCGAC CCGCTGGAAG CAGAGCCGCC GGCGTGCGAG 
CTGAAGCCGC CCTTCCACTC CCTGGACGGC GGTCTGGAGC GCGTCCCCGC CGCGCCCGAC 
GGCCCGGTCA AGGAGGCCTC AGGCGCGCTC CGGATGTCTC TGGCCGCGGG TGGCGGAGCT 
GCTCTGGACG AGGACCTGGA GAGGGCCCGG AGCTGTCTCC GCAGCGCGGC GGCCGGGCCG 
GAGCCACTGC CGGGCGCAGA GGGCGGCCCT CAGGTCTGCG AGGCCAAGCT GGGGTTTGTG 
CCGGCGGGGG CGTCGGCAGG CCTGGAGGCT AAGCCGCGCA TCTGGTCCCT GGCCCACACA 
GCCACCGCCG CCGCCGCCGC CGCCACCTCC CTGAGCCAGA CTGAGTTTCC GTCGTGCATG 
CTCAAGCGCC AAGGTCCCGC GGCCCCTGCG GCTGTGTCCT CCGCGCCCGC CACGTCCCCG 
TCTGTGGCCC TTCCCCACTC TGGCGCCCTG GACAGGCACC AGGACTCCCC GGTAACCAGT 
CTCAGAAACT GGGTGGACGG GGTCTTCCAC GACCCCATCC TCAGGCACAG CACTTTGAAC 
CAGGCCTGGG CCACCGCCAA GGGCGCCCTC CTGGACCCCG GGCCTCTGGG ACGCTCGCTG 
GGGGCGGGCG CGAACGTGCT GACTGCACCC CTGGCCCGCG CCTTTCCGCC TGCCGTGCCC 
CAGGACGCCC CAGCTGCAGG CGCCGCCAGG GAGCTGCTCG CCCTGCCCAA GGCCGGCGGC 
AAACCCTTCT GCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variants at IRX4 as prostate cancer expression quantitative trait loci.
European journal of human genetics : EJHG22(4)558-63(2014 Apr)
Xu X,Hussain WM,Vijai J,Offit K,Rubin MA,Demichelis F,Klein RJ

IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Human molecular genetics21(9)2076-85(2012 May)
Nguyen HH,Takata R,Akamatsu S,Shigemizu D,Tsunoda T,Furihata M,Takahashi A,Kubo M,Kamatani N,Ogawa O,Fujioka T,Nakamura Y,Nakagawa H

Two novel mutations of the IRX4 gene in patients with congenital heart disease.
Human genetics130(5)657-62(2011 Nov)
Cheng Z,Wang J,Su D,Pan H,Huang G,Li X,Li Z,Shen A,Xie X,Wang B,Ma X

Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
PloS one6(7)e22106(2011)
Sch?rks M,Buring JE,Ridker PM,Chasman DI,Kurth T

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

IRX4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報